Semaglutide and Vomiting: What Users Say (Page 3)

• Bis...
• April 7, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "I am going on week 11 with Ozempic, and have lost 24 pounds. I have had all 5 of the main side effects, nausea, stomach pain, vomiting, diarrhea, and constipation. I am happy with the weight loss, so am learning to manage these. By trial and error, I've found that I can't eat much at one time (don't really want to), need to avoid fatty foods, drink lots of fluids, and take Senna laxative every night for the constipation, and keep Zofran around to help with nausea. Yes, these first few weeks have been difficult, but the weight loss is worth it to me. Plus, the side effects get less the longer I'm on Ozempic. I am currently on 1.0 mg and think that's quite enough. I am rarely hungry and often have to make myself eat. I hope to lose 65 pounds total."

• Thi...
• June 27, 2018

Semaglutide for Type 2 Diabetes "I've been taking this for 2.5 months. I've lost a solid 10 pounds. I take it right before bed so I can sleep off the initial side effects, if any. There is a little bit of diarrhea, nothing too crazy. I have major loss of appetite, I can eat half meals or half kids' meals and I'm always full after a few bites. Sugars are low. The major side effect is nausea, but it isn't every day. I've thrown up 3 times within the past 3 months, which is something I never did prior. It comes out of nowhere, and honestly, I'm unsure if it is this injectable or just from taking an iron supplement and vitamin. Could be the vitamin. I feel tired also, not sure if it's just work or a side effect. Overall, I'm happy with the injectable, plus it beats taking a pill every day."

• nau...
• December 30, 2020

Semaglutide for Type 2 Diabetes "I started Ozempic .25 mg subcut 8 days ago. I took my second dose yesterday. My first week, I ended up in the ED. I thought I had a bowel blockage or ileus. The ED visit was preceded by 6 hours of constant, sickening, odiferous belching, constant flatus, eruptive vomiting, cramping, and pain. A CT scan revealed gastric paresis. The event was precipitated by a fatty meal. I have since learned that the decreased gastric motility demands drastic changes in the volume of food intake, fat content, and most importantly, patience with what I consider to be major side effects. Now, I have no appetite. I am nauseated all the time, taking Zofran 4 mg before any meal. The belching is greatly reduced, same with flatus. I feel constipated, but that is easing off. I am avoiding high-fat foods and eating smaller portions. I am profoundly fatigued. Tomorrow, I am getting on the treadmill for 30 minutes each day to stimulate endorphin release to feel better. I have read the symptoms are reduced after 4-6 weeks."

• Com...
• Taken for less than 1 month
• June 10, 2023

For Weight Loss (Obesity/Overweight) "Started on May 23 at a 0.125 mg dose and spent the entire Memorial Day weekend sicker than I've ever been. I didn't put two and two together until after I took my second dose on May 30. Two nights later, I woke up with my body uncontrollably shaking, and I had my hand on my phone, ready to call 911. I didn't take my third dose on June 6 and don't plan to ever again, despite my doctor telling me to take a two-week break and retry it. He says the side effects are typically more tolerable after a two-week break, but I'm not willing to chance it. Since day one, my symptoms have been extreme fatigue, making it impossible for me to function in daily life. I can't do my job and I'm hardly able to be there for my kids without pushing myself as if my life depended on it. I've been missing out on everything for over three weeks because all I can do is go from bed to couch. Additionally, I've experienced severe confusion, heaviness in my head, nausea, and vomiting, and I've lost 16 pounds."

• Anonymous
• Taken for less than 1 month
• March 25, 2022

Semaglutide for Type 2 Diabetes "After 2 injections of .25, I started having watery diarrhea. On day 3, I woke up and the diarrhea had leaked out and was in my underwear. I started violently vomiting that same evening. This was day 4 of diarrhea, now with vomiting. My blood sugar levels kept crashing. I rushed to the ER, I had an X-ray, every lab work/panel you can think of, and a CT scan - nothing. Ozempic is the only culprit. I am texting this review from my hospital bed. I was admitted and put on fluids and a liquid diet. They are trying to keep the nausea under control and stop these symptoms before it affects my kidneys from being dehydrated. The Ozempic has been thrown in the garbage, but I don't know how long the nightmare from that so-called medicine will last."

• jma...
• Taken for 1 to 6 months
• January 27, 2023

Semaglutide for Cardiovascular Risk Reduction "I started on the lowest dose of Ozempic in October 2022. One injection, in my thigh, once a week. I didn't make it past the first 4 weeks or the lowest dose. My physician hoped that since I do not have a gallbladder, many of the reported side effects of nausea and vomiting would not affect me. Wrong. First week and all things went well. I experienced no real side effects and had decreased appetite and energy. I slept well and was active. Second, third and fourth weeks, not so good. Modified my entire diet, but could barely eat or drink anything but a little chicken. Constant and severe nausea, vomiting, sleep deprivation, headaches, body aches, and zero energy for the next three weeks. It was like having a severe case of stomach flu for 4 weeks. Oh, I lost weight, between 18-20 lbs. Unfortunately, this is not a sustainable way of life. I couldn't function; I didn't leave my house for a month. I pulled myself off of it, and it took another 3 months to recover fully."

• Hop...
• Taken for 1 to 6 months
• January 7, 2022

Semaglutide "I've been on Rybelsus for about 6 weeks now and am up to the 7 mg dose. I was placed on it to help lose PCOS-induced weight gain. It took about a month to get used to (minor vomiting, nausea, constipation, and diarrhea during the adjustment). I've lost almost 15 lbs, my anxiety levels have plummeted, and my skin is the clearest it's been in ages. I no longer have sugar or processed carb cravings, which I think is helping all of this. I'm lucky that my insurance is fully covering the medication since it is pricey."

• Dia...
• Taken for 6 months to 1 year
• June 2, 2019

Semaglutide for Type 2 Diabetes "I’ve been on Ozempic about 8 months. I went to the 1 mg dose pretty quickly. My sugars became normal. I was losing about 5 lbs every two weeks. My A1C went from 6.8 to 5.6. No side effects at all. I’ve lost about 30 pounds overall. About 6 weeks ago, I got sulfur burps, then nausea, then vomiting. I vomited 9 times over maybe 6 hrs. Thought it was food poisoning. Yesterday, I again got sulfur burps followed by nausea and then vomiting. This morning again, burps, vomiting, and watery diarrhea. Thought it odd it would again be food poisoning. I never get sick. Then thought maybe it was E. coli or gastroparesis. Then I happened upon this site and started reading the reviews of Ozempic. I don’t know why it would take so many months for any side effects to show, but it sounds like this is most likely the cause of my vomiting and diarrhea. I took my last dose two days ago. I take it every two weeks. I think I’ll cut back to 0.50 next time and see what happens."

• blh...
• Taken for less than 1 month
• May 31, 2024

Semaglutide for Weight Loss (Obesity/Overweight) "First dose 0.25mg, had slight stomach pain/discomfort. Later that same night, my appetite disappeared. Just seeing a fast-food commercial on TV made me feel nauseous. I thought if that's the worst of the side effects that affect me, then I'll be very happy with that. By the next day, stomach pain and nausea increased. By 4:00 am, BAM! Diarrhea, severe stomach pain, projectile vomiting, headache, chest pain, severe itching mainly on the palms of my hands and arms. I truly thought 'this must be what it feels like to be poisoned!' I was scared. It is now the next day and I feel fine. A little tired from lack of sleep from feeling so sick. I think I will do my second dose next week...but I'm quite nervous of a repeat of feeling like I was dying from the stomach pains and vomiting. Will I continue with this drug?...jury is still out! On the positive side, I've already lost 5 pounds; but of course, I can't & don't want to eat, too much nausea and vomiting."

• No ...
• March 1, 2020

Semaglutide for Type 2 Diabetes "Victoza was no longer working to lower my A1C, so my doctor prescribed Ozempic. It’s been 4 weeks. Since I’d been on the maximum dosage of Victoza, she assumed it would be a smooth transition to the maximum dose of Ozempic. While it did reduce my blood sugar, I’ve had every side effect: nausea, vomiting, explosive diarrhea, heart palpitations, heartburn, and disgusting burping. Some days, I can’t leave the house. I didn’t immediately realize that these symptoms were related to the medication, so I continued to inject the maximum dosage. I thought I had a horrible bug. After the second week, I made the connection. So I went down to a half dose, but that wasn’t enough. Now I’m down to .25. I’m still having side effects, so for now, I am on 2 Prilosec, 2 Zofran, and 4 Imodium per day. My blood sugars are down, sometimes dangerously low. I lost weight, but of course, I would with the nausea, vomiting, and diarrhea. I’m going to try to stick it out."

• she...
• Taken for 1 to 6 months
• May 21, 2019

Semaglutide for Type 2 Diabetes "I started at a dose of 0.25 mg Ozempic, advancing to 1 mg weekly. The first week, I experienced reduced appetite and some nausea. Within 3 months, I have lost 35 pounds, and my HgA1C went from 9 down to 6. I have, on several occasions, experienced nausea and vomiting if I overate or had very greasy food. It does reduce your appetite substantially. I found eating my main meal at lunch and soup for supper has reduced nausea."

• Anonymous
• Taken for less than 1 month
• June 11, 2022

Semaglutide for Cardiovascular Risk Reduction "I started Ozempic for weight loss. I took dose 1 of 0.25 week 1 and had a little nausea. I took dose 2 on Saturday morning when I was supposed to. On Sunday, I felt terrible with nausea. Sunday night, I was vomiting and had diarrhea with major stomach pains. These symptoms have now lasted 6 days. My body is in so much pain and discomfort from vomiting and diarrhea and unable to eat or drink. I would never recommend this drug to anyone. The side effects are so terrible that I would not want to take the chance. I’m hoping these symptoms will go away soon."

• Jan...
• Taken for 1 to 6 months
• October 11, 2021

Semaglutide for Cardiovascular Risk Reduction "This was prescribed by a weight loss nurse, second time use. First time on .25 mg was okay, but as soon as I go up to .5 mg I am so sick. Diarrhea, nausea, vomiting, sulfur burps, it's horrendous!! I do not having tried twice now, with the same effects each time I can say 100% do not try this for weight loss. It is not worth it. It takes 5 weeks to clear the body too!"

• Dee...
• Taken for 1 to 6 months
• April 10, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "I wish I did more research before starting this. I started on Saxenda and worked up to 3.0 mg, the max dose. I had a few bouts of severe diarrhea and vomiting. I lost a total of 15 pounds and then started getting ravenous. Then I got switched to Wegovy 2.0 mg and then moved up to 2.4 mg. I only had a couple of incidents of terrible nausea, usually when I ate greasy, heavy, or fried foods. But generally, I feel like crap every day. Once on the Wegovy, the weight literally fell off. Mostly because I just didn't think about eating anything, or my appetite would be satisfied with a very small portion of food. The biggest side effect is skin irritation; like a constant sunburn. Clothes touching my skin bother me. Or riding in a car and bouncing. It became intolerable. And chills make my skin ache. I easily surpassed my goal weight and now trying to decide if I want to quit it altogether or reduce the dosage and hope the skin irritation goes away."

• JRo...
• Taken for 1 to 6 months
• October 29, 2019

Semaglutide for Type 2 Diabetes "Within 2 weeks after moving from the starter dose of Ozempic to 0.25 to 0.5, I began having vomiting in the wee hours of the morning, with increasing intensity, nearly every night for the last 2+ weeks. The last 4-5 have been really rough. I also take metformin 500 and glimepiride 2, both AM and PM. This weekend, I went down to the Ozempic 0.25 dose, but Sunday and Monday nights were both awful bouts of vomiting. (No diarrhea at any stage with Ozempic; occasional nausea during the day, very decreased appetite.) Is anyone else having this bad and persistent vomiting? Thanks and good luck."

• Pea...
• October 25, 2018

Semaglutide for Type 2 Diabetes "I started taking Ozempic 3 months ago. I found that after I take my injection on Wednesday night, I get nausea before the day is over and vomit. It feels like my food gets stuck and won’t move. I get sick at least once a week, then I’m better. My appetite has decreased. I also notice I can’t overeat, or I get sick. I have told my doctor, he thinks it will get better. I know one thing for sure: you can’t cheat with fried food, or you will be sick for sure. I’m going to try one more month."

• Anonymous
• Taken for 1 to 6 months
• June 21, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "I have lost 37 lbs in 3.5 months, but should be more due to the horrific side effects. Burping, belching, vomiting, diarrhea, chest pain, nausea, blurry vision, basically every side effect imaginable. I never had side effects from any medications before. I continued to increase the dose up to 1.7 mg and hope for the best with no success. I have three more weeks of misery, but due to the cost of $586, I refuse to trash this medication."

• Dro...
• Taken for 6 months to 1 year
• April 2, 2025

Semaglutide for Type 2 Diabetes "I've lost about 40 lbs since starting Ozempic 11 months ago. My A1C is now within normal limits, but I still take Metformin. My non-alcohol fatty liver disease has resolved as well. I experienced nausea and vomiting early on in treatment, but that has mostly resolved. I feel hunger less and feel full longer. Constipation is a big problem, so I use an occasional stool softener or eat some prunes to keep things moving. The medication decreases the pleasure I get from food, which is weird sometimes. When I go out of town, I used to look forward to trying a new restaurant, but now it's just 'meh' no matter what I eat. I found that I have more nausea if I inject in the abdomen, so I do it in my arm or thigh instead."

• joh...
• Taken for 1 to 6 months
• June 16, 2025

Semaglutide for Type 2 Diabetes "Reduced blood sugar from 10 to 7.1. Killed my hunger completely, no more food cravings. Side effects became disabling, had to discontinue using. Became bloated, nausea was bad, 1st time I have vomited in 50 years, fatigue, constipation, going to the emergency room as no doctors available to help."

• ERM...
• Taken for less than 1 month
• February 25, 2019

Semaglutide for Type 2 Diabetes "This drug should be taken off the market. Side effects are severe. Belching, uncontrollable diarrhea, dehydration, nausea, vomiting. Be prepared to not leave your bathroom for 3 days every week. Not to mention, the ads are by far the most annoying on TV."

• AK4...
• Taken for 1 to 6 months
• April 11, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "I started Ozempic for weight loss. I paid cash since I wasn't approved by insurance. I was about 15-20 pounds overweight and pre-diabetic with a family history of type 2 diabetes. No matter what I did, nothing made me lose weight. The first month at .25 mg was a dream come true. I had no appetite and felt very few side effects. I lost 10-12 pounds in the first month. The 5th shot was .5 mg. I became so ill. It started with huge belches and nausea. That night I vomited and was so lethargic and nauseous that I didn't get out of bed for 3 days. I had weird sores on my tongue. The next day I vomited again. I had to get Zofran for the nausea, which helped a bit. Almost a week later, I am due for this week's shot, and I have decided not to continue. I still have the belches from hell, weakness, and lethargy, but I am at least able to function and work. Climbing the stairs feels like Mt. Everest. I hope I feel normal again soon."

• PDH...
• Taken for 1 to 6 months
• June 21, 2019

Semaglutide for Type 2 Diabetes "I started Ozempic about 3 months ago at .25 mg. My doctor made me start my 1st dose on a Monday in her office because I would tell her I would try and then never do it. Tuesday morning I was good, then by Tuesday night, stomach cramps, nausea, vomiting, and diarrhea, till the wee hours of the morning. The symptoms slowed down throughout the week. Even though I was losing at least 3-4 pounds a week, a total of 35 pounds within a 2 1/2 month period. My A1C did go down, the side effects are deadly. I like the fact that I am losing weight, but I hope I don't have permanent damage from this medication."

• Bai...
• Taken for less than 1 month
• July 3, 2019

Semaglutide for Type 2 Diabetes "At first, I had a brief overwhelming bout of nausea that passed. Decreased appetite definitely had me losing weight, but after the second injection, the nausea got much worse! Plus, I had diarrhea/vomiting, and it just got worse daily. I had to discontinue. Now it's been a month later, and I'm still having nausea and diarrhea. Horrible experience for me."

• Nes...
• Taken for 1 to 6 months
• May 3, 2019

Semaglutide for Type 2 Diabetes "Was diagnosed with type 2 diabetes in March 2019. Doctor put me on Ozempic rather than insulin, although it's not recommended. He thought it was worth a try along with 500 mg metformin twice daily. The first 3 weeks of 0.25 mg Ozempic were just fine. Very minimal side effects - occasional diarrhea, some gas, and belching. Nothing I couldn't handle. The fourth week of 0.25 mg was worse. Constant diarrhea for four days, nausea, some vomiting. I went to a different doctor thinking I had a stomach virus, he prescribed me an anti-diarrheal, and I felt better. I took the Ozempic at 0.5 mg then, as prescribed. Two days later, nightmare. Diarrhea again, vomiting, nausea, and serious fatigue. I'm in the throes of it right now, and I'm going to be contacting my doctor to see what I can do to counteract this. Besides the side effects, though, it's working beautifully. My blood sugar is down from the high 300s to the low 100s in just a month."

• Big...
• Taken for less than 1 month
• April 11, 2022

Semaglutide for Weight Loss (Obesity/Overweight) "Took my injection .25 mg Friday afternoon and had a very hard time eating dinner. By noon Saturday, I was violently ill with diarrhea, vomiting, and a fever. The symptoms subsided by Sunday, and I was left very achy and fatigued. On the upside, I guess I did go from 335 lbs to 318 lbs over the course of the weekend. This medication is not for the faint of heart. It is very depressing to see a full-course meal in front of you and only be able to eat a few bites. If you are serious about losing weight, this medication will get you there, but I wonder if it’ll work or if the side effects will at least subside with longer-term use. The nausea is horrible, but you do also have some beautiful dreams while taking it."