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Semaglutide and Headaches: What Users Say (Page 4)

Brand names: Ozempic, Rybelsus, Wegovy

Reviews for Semaglutide

Commonly mentioned side effects
  • Jen...
  • Taken for 1 to 2 years
  • October 22, 2024

For Weight Loss (Obesity/Overweight) "I started taking semaglutide in April of 2023 and was at my highest weight ever (230 lb) and perimenopausal. I have never really struggled with weight gain until my 40s, and when I hit 230, I was seriously considering if I would be a candidate for bariatric surgery, but thankfully someone suggested semaglutide. I did experience side effects-nausea, headache, some constipation-but I have lost 70 lbs, and I think taking semaglutide was worth it."

9 / 10
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  • lee...
  • Taken for less than 1 month
  • May 4, 2023

For Type 2 Diabetes "On my second week of semaglutide for my diabetes and have had severe abdominal and back pain, waves of nausea, headaches, bloating, and heartburn, not really sure it's worth taking it, especially when I don't really understand why it's been released to the public due to the risk of cancers like pancreatic cancer, especially as I'm a diabetic and already at risk of it. But I am going to a diabetic educator and will be getting the latest and safest medicines and advice, so if I'm told to stop it, I will... but I am persevering with it at the moment. It's a pity though, as I have heard it does work to control diabetes, and as I'm older now and in need of ridding myself before it's too late. I feel I must, but it has been dreadful so far with these side effects and especially at work. Hopefully it all works out or I will have to stop taking it... it's also hard when I'm supposed to stay on it, but it's in limited supply."

4 / 10
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  • Mar...
  • Taken for 1 to 6 months
  • May 24, 2025

For Weight Loss (Obesity/Overweight) "I have had all of the less common side effects, primarily belching, excess gas, swollen stomach, headache, and nausea. I’m not sure yet if eating certain foods causes it. I ate Indian food, and it was awful for two days. But I feel okay generally, and it seems to be working, so I’m happy about that."

8 / 10
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Frequently asked questions

  • Vic...
  • Taken for less than 1 month
  • December 9, 2024

Semaglutide for Type 2 Diabetes "I have been taking .25, and I am suffering nausea, headache, and bloating. I thought it would be better after the first 2 weeks, but it's worse. I think I will have to stop taking it. I have not seen any benefits."

4 / 10
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  • Mom...
  • Taken for 1 to 2 years
  • June 24, 2023

For Type 2 Diabetes "The medication worked well. In the beginning, it definitely delivered great results. A1C was down, weight followed, however, the gallbladder problems began after about 9 months. Constipation, clay stool, nausea, headache, flu-like symptoms. I just stopped taking it. Because I have developed healthy eating habits, vegetarian, I am doing well. Just got diagnosed with Sjogren's disease, not sure if Ozempic had something to do with it?"

6 / 10
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  • 65...
  • Taken for 1 to 6 months
  • March 1, 2025

Semaglutide "I'm on week 5 in a few days. Started at 0.25 cc inj. Mild nausea and headaches. 5' 10'', 186 initial weight. I'm 40 lbs overweight. I tried to eat right and exercise, but the weight was not budging. Just going up, and I'm very active outside. Today I'm down 10 pounds, it's a slow process for me, it seems. Very little appetite, and you can't eat much at one time or you feel terrible, bloated, nauseated, headaches... but I'm determined to drop another 30 lbs. I'm just surprised at how little I eat for a portion and am completely full... and still the weight clings on. I could not do it without this drug."

7 / 10
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  • fis...
  • Taken for 1 to 6 months
  • February 20, 2025

For Weight Loss (Obesity/Overweight) "After 7 weeks, I've lost 10 lbs. Minimal side effects, nausea occasionally, some headache, probably because I don't drink enough water. Definite decrease in appetite and full after very small portions. One would think the weight would have fallen off, but it's been about 1+ lbs a week. My dose has been .25 ml, on week 8 it is .50 ml. We shall see. I'm committed to losing 40 lbs, 30 lbs to go. I eat nutritionally rich foods, no junk, period, protein-rich fish, venison, and seafood, any kind of salad, but the weight has been so hard to drop. I'm not really hungry and late-night snacking desires, just gone, a thing of the past, so it's a kind of painless waiting game on this medication."

7 / 10
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More FAQ

  • Wan...
  • Taken for 1 to 6 months
  • June 10, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "I've been taking Wegovy since September (2024). I initially did not like the way it made me feel. I was experiencing constipation, headaches, and nausea. My next dose was 0.50, which the pharmacy was out of until this past April 2025. I was determined to see if I could withstand the side effects. My appetite was suppressed immediately. I experienced constipation, which I counteracted with stool softeners every day. I took Zofran for the nausea. I had started riding my stationary bike around the same time that I started Wegovy. On April 17th, 2025, I started walking 30 minutes a day. I am now at a 1.7 dose. Side effects are minimal. I noticed that if I am constipated, I would get nauseous. Stay away from heavy grease. I consume a protein shake every morning and try to eat meat as much as I can as I do not really have a taste for meat or I no longer like alcohol. I am happy that I tried it again. I am 6'1" and was 283. I am 266. I want to be 240. Yay!"

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • January 5, 2024

For Weight Loss (Obesity/Overweight) "I was only able to use 1 injection of semaglutide, the side effects hit me so bad that I couldn’t continue the medication. I got the injection on a Friday, and 2 days later, I had a seizure, which I ended up in the hospital. I had no appetite at all, but the constant headaches and nausea were too much."

2 / 10
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  • Sic...
  • Taken for less than 1 month
  • June 11, 2022

Semaglutide for Weight Loss (Obesity/Overweight) "Doctor skipped to 1.7, and I’ve been sick going on 4 days now. Severe nausea and vomiting, stomach pain, and headache, dehydration."

1 / 10
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  • Jul...
  • Taken for 1 to 6 months
  • November 19, 2024

Semaglutide for Type 2 Diabetes "It is helping me lose weight, but very slowly. I am experiencing a lot of nausea and vomiting, and headaches, and my stomach is not feeling good. I am on a 0.5 dosage a week."

10 / 10
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  • Ser...
  • Taken for less than 1 month
  • July 25, 2024

For Weight Loss (Obesity/Overweight) "I had a headache for the first 4 days... I guess it's been okay since then. Lots of nausea, and I can't stand much food, but I guess that's the whole idea."

7 / 10
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  • Mar...
  • Taken for 1 to 2 years
  • June 5, 2024

For Weight Loss (Obesity/Overweight) "Terrible. Headaches, nausea. So bad I had to miss work. It was great initially, but now the side effects are terrible."

6 / 10
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  • Lin...
  • Taken for 1 to 6 months
  • October 12, 2021

Semaglutide for Type 2 Diabetes "I have been sick ever since I started taking Ozempic: diarrhea, headaches, weight loss, nausea, throwing up. It's a bad medication."

5 / 10
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  • Jul...
  • Taken for 1 to 6 months
  • May 11, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "Good with some mild nausea and headache hours after injecting. Lost 7 lb in first month. I do not have cravings and I am satisfied with small meals."

8 / 10
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  • Pam...
  • Taken for less than 1 month
  • December 19, 2024

Semaglutide for Type 2 Diabetes "So this week I started on .25 on my Ozempic. I'm pretty excited to see how I do. The second day I was really nauseated and had a headache, but now I feel better. But let's see with the next shot."

8 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.