Semaglutide and Headaches: What Users Say (Page 2)

• Liz...
• Taken for less than 1 month
• December 16, 2019

Semaglutide for Type 2 Diabetes "On the fence. Took my first shot of Ozempic .25 last Wed at the doc's office. I was nervous as I couldn't tolerate Metformin's side effects. But she reassured me this was gonna be the answer to my prayers, so I agreed to try it. First day I was fine, then they hit. Woke up feeling dizzy, nauseous, and shaky. My fasting blood sugar was 157. Lower than it's been in quite some time. Ozempic does its job. My BS has been managed quite well. I definitely don't have an appetite. Have to make myself eat and drink. Have very low energy. Tired all the time. Aside from that, it's the other side effects I'm having trouble living with. Waking up in the wee hours of the morning clammy with severe nausea, mild headache, and dizzy. But it's only been 6 days. The constant nausea, dizziness, and headaches are almost unbearable. Not sure if I'm gonna continue. If the effects are like this now, what are they gonna be with the increased dose? There's gotta be a better way!"

• Hat...
• Taken for less than 1 month
• July 19, 2022

Semaglutide for Cardiovascular Risk Reduction "This is the worst medication I have ever had. Side effects of egg burps, vomiting, bloating so bad. DO NOT TAKE THIS. 30% of people that try this drug end up having problems with it. DO NOT TAKE. You can't eat, everything that goes into you makes you want to throw up. DON'T TAKE! Never-ending nausea and weakness. DON'T USE, SAVE YOURSELF. Headaches....."

• Dck...
• January 13, 2021

Semaglutide for Type 2 Diabetes "I’ve been on Ozempic for 8 weeks, .25 starter dose for the first 4 weeks; it suppressed my appetite, a couple of mild headaches, and intermittent nausea. Moved to .5 at week 5 and have no desire to eat at all. It’s almost a problem as I feel so weak and have all-day nausea. Hard to tell if the nausea is from not eating, Ozempic, or both. At week 6, I also started taking Humira for spondyloarthritis; the combined side effects are brutal. Sick nearly 24 hours a day, constant nausea, vomiting with any exertion. Backed off the Ozempic to .25; the side effects are better, but still troubling. As a positive, I’ve lost 30 lbs in 8 weeks, all from not eating as I feel too sick and weak to walk or work out. The docs prescribed Zofran 8 mg po every 8 hours as needed. It helps, and I do manage to eat a couple of small meals. Weigh the benefits and downsides, but it does work. A1C dropped from 8.7 to 7.4 in the first 8 weeks and should continue downward with prolonged use and accompanied weight loss."

• Lad...
• Taken for less than 1 month
• February 19, 2022

Semaglutide for Cardiovascular Risk Reduction "Went to my endo, desperate from dealing with both hypothyroidism and menopause. Have regularly put on 30 kg over the past 5 years up to 114 kg, have extreme fatigue, spine issues, and severe leg pain/body aches. Was prescribed Ozempic to assist with weight loss as nothing else worked. I was very worried about side effects and it not working after reading reviews. Started my 0.25 mg dose 3 days ago, injecting in the upper thigh just before bed, but didn't get the full dose as I pulled it out a tad early. Had some mild nausea the next morning that only lasted a few minutes and developed a headache, but panadol took care of that. I didn't notice much the first day and was worried that it wasn't going to work. However, on day 2, I was only able to eat about 1/3 of my dinner and felt full. Have already lost 0.5 kg in just 3 days. No other side effects that I can tell. Though I do feel more thirsty and am a bit tired; however, that's normal for me, so can't say it's a side effect. Happy so far!"

• IBN...
• July 4, 2021

Semaglutide for Type 2 Diabetes "I have been on Ozempic for 3 weeks. Yes, it is making me lose weight, obviously because I'm so nauseated all the time that I can't eat. I have stomach cramps, constipation, headaches, body aches, and nausea so severe that sometimes I can't even lift my head up. I'm really trying to give it a chance since a once-a-week injection seems better than taking a bunch of pills. I just don't know how much longer I can suffer with the terrible nausea and stabbing stomach pains."

• Jus...
• Taken for less than 1 month
• April 7, 2022

Semaglutide for Cardiovascular Risk Reduction "My daughter was given Ozempic to help with weight. She has lupus, and with the steroids, she had gained around 30 pounds, which is horrible since she has always been in prime condition with her dance. She has struggled ever since with the weight, even after cutting all carbs, white processed flour, gluten, and anything with corn syrup. We went to no processed foods, fresh fruits and vegetables, as well as exercise. Gave her the first injection (0.25) around 6 p.m. All was good until 11 p.m. that night. She woke us up so very sick. Extreme nausea, then the worst headache ever set in. She thought her head was going to explode. She was shaking all over, extremely lightheaded, and then said she was 'on fire' inside her body. She then totally passed out. Had to go to the ER, we were so afraid. Never again!!!!"

• JLa...
• Taken for 1 to 6 months
• May 3, 2019

Semaglutide for Type 2 Diabetes "I've been on Ozempic 0.25 for five weeks, it's great for losing weight, but the side effects are not worth it. Let me review what Ozempic has been like. The first three weeks were okay, and then I started noticing nausea, stomach burning, headache, dizziness, upper back pain, severe constipation, and feeling very tired and depressed. I ended up in the ER with a mild pancreatic attack and high lipase levels. I've had no desire to eat or even drink water. It makes me gag, and I used to drink a lot of water. I'm done with these injections. I will stay on my metformin, but I can do better on a healthy eating lifestyle than on Ozempic and all the negative side effects. Quality of life has gone from a 10 to a 1, and that is not me. I'm taking my life back. It's really just healthy eating, and we can all do that with willpower. Good luck to everyone else."

• Sam...
• Taken for less than 1 month
• October 2, 2019

Semaglutide for Type 2 Diabetes "I am a type 2 diabetic, but just took my first and last dose of Ozempic 25 mg. I had been taking Belviq and Phentermine, which actually helped me lose 20 lbs without side effects and dropped my A1c from 8 to 6.8. I wanted to try something different. Never again will I use this drug. Day 4 of the first week, and I am so dizzy, nauseous, headache, I can hardly walk. Also sweating, shaky, and my heart rate has dropped. Using Zofran and Dramamine to help the nausea. Trying to push lots of fluids. Praying this doesn’t take 5 weeks to go away. Beware."

• Dix...
• Taken for less than 1 month
• June 11, 2022

Semaglutide for Cardiovascular Risk Reduction "Two days after my first injection, I had horrible sulfur burps that were making me feel sick. By that evening, I had horrific stomach cramps; by 11:30 pm, I had uncontrollable diarrhea! My prescriber advised me to eat six small meals a day and that the symptoms would improve with each injection. I left it twelve days before my next one (as I had a couple of social things I didn’t want to miss if it happened again) and thought at first it was better. A headache day one, nausea on day two, but sulfur burps again by day three. I got indigestion medicine, but it didn’t even touch it. That night, same again; cramps, diarrhea, more burps, and this time intense nausea too. I decided at that point it might not be for me! I really hope it helps some people lose weight, but don’t expect a quick easy fix! I actually felt fatter the whole time I was on it as I was so bloated and tender."

• Mar...
• Taken for less than 1 month
• August 21, 2019

Semaglutide for Type 2 Diabetes "I took my first dose a week ago. I began to have a reaction the next day. It started with a mild headache, a little nausea. Then, as the week progressed, I began to be super lethargic, tired, taking day naps. Fast forward to Sunday, I am literally near passing out at a wedding. This is not for me. I will continue to watch my calories and stay on my regular regimen. I have been ill for 4 days and can't wait for this to be over."

• Avi...
• Taken for 1 to 6 months
• July 16, 2024

Semaglutide for Weight Loss (Obesity/Overweight) "I am 58, have IBS-D, no gallbladder, GERD, and am 60 lbs overweight. This is my second attempt at taking Wegovy. The first attempt was disastrous! I didn't make it through the first week before I was hit with diarrhea, nausea, acid reflux, dizziness, cramps, and had headaches. I missed four days of work and went to ER twice. The doctor did tell me to stop taking this, but I honestly did not think it was the Wegovy (I had not done any research on side effects). Once I got back to my normal state of digestive issues, I became proactive. I started back on Wegovy (.25 lowest dose) 6 weeks ago, but now I take a dose of Pepto-Bismol daily (twice a day the day of and day after the shot) and I take an OTC daily antacid. I still get mild side effects (nausea, headache, and fatigue) the day after the shot or if I overeat. I have not lost any weight at this dose so I am going up to the .5 dose next week. As others have said - everyone will react to this med differently."

• jma...
• Taken for 1 to 6 months
• January 27, 2023

Semaglutide for Cardiovascular Risk Reduction "I started on the lowest dose of Ozempic in October 2022. One injection, in my thigh, once a week. I didn't make it past the first 4 weeks or the lowest dose. My physician hoped that since I do not have a gallbladder, many of the reported side effects of nausea and vomiting would not affect me. Wrong. First week and all things went well. I experienced no real side effects and had decreased appetite and energy. I slept well and was active. Second, third and fourth weeks, not so good. Modified my entire diet, but could barely eat or drink anything but a little chicken. Constant and severe nausea, vomiting, sleep deprivation, headaches, body aches, and zero energy for the next three weeks. It was like having a severe case of stomach flu for 4 weeks. Oh, I lost weight, between 18-20 lbs. Unfortunately, this is not a sustainable way of life. I couldn't function; I didn't leave my house for a month. I pulled myself off of it, and it took another 3 months to recover fully."

• blh...
• Taken for less than 1 month
• May 31, 2024

Semaglutide for Weight Loss (Obesity/Overweight) "First dose 0.25mg, had slight stomach pain/discomfort. Later that same night, my appetite disappeared. Just seeing a fast-food commercial on TV made me feel nauseous. I thought if that's the worst of the side effects that affect me, then I'll be very happy with that. By the next day, stomach pain and nausea increased. By 4:00 am, BAM! Diarrhea, severe stomach pain, projectile vomiting, headache, chest pain, severe itching mainly on the palms of my hands and arms. I truly thought 'this must be what it feels like to be poisoned!' I was scared. It is now the next day and I feel fine. A little tired from lack of sleep from feeling so sick. I think I will do my second dose next week...but I'm quite nervous of a repeat of feeling like I was dying from the stomach pains and vomiting. Will I continue with this drug?...jury is still out! On the positive side, I've already lost 5 pounds; but of course, I can't & don't want to eat, too much nausea and vomiting."

• Ano...
• Taken for 1 to 6 months
• April 8, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "I am in week 10/injection 2 of 1 mg and taking Wegovy for weight loss. I started at 142 kg and am down to 132 kg, which is wonderful. My goal weight is 115 kg as I'm tall and solid build. The side effects, nausea, fatigue, headaches, and some bowel upsets tend to dissipate 3 days after the injection. Avoid big meals and heavy/fatty foods in particular to minimize side effects. Not enjoying food and the social side can be a bit tough, but the results far outweigh any downsides. You actually save money overall due to eating less. I intend to stay the course and highly recommend this life-changing experience."

• Bet...
• Taken for less than 1 month
• July 5, 2019

Semaglutide for Type 2 Diabetes "Only second week in on the lowest dose. Feel lighter, no hunger at all. Suffering from nausea, wind, and headaches. I would really like to go the distance with this medication. I have overeaten for years and am wanting this to work. Not thinking of eating is quite liberating."

• Pat...
• Taken for less than 1 month
• June 24, 2022

For Weight Loss (Obesity/Overweight) "This was the worst medication I have ever taken. I was sick, literally so sick to my stomach I could not concentrate. I lost 3 days of work and was not given anything by the weight loss center for the extreme nausea. I also had side effects of headaches, my BP rose to a point it has never been, I felt so weak and tired, looked like death, I had no color in my face. I literally have a cast iron stomach and nothing ever bothers me, this, however, was a pure nightmare. It is not worth taking for losing a few pounds, please stay away from this drug. I had to literally stay as still as I possibly could so I would not throw up. For whatever reason, I even lost my taste, and it has been 10 days. I just can't say enough bad things about this medication. I am just a regular mom trying to look my best and thought this would help, however, this is one of the biggest mistakes I have ever made and I still regret it. Please think twice before you inject this into your body, I wish I had done more research. Hopefully, I can help someone else."

• mnd...
• Taken for less than 1 month
• March 14, 2019

Semaglutide for Type 2 Diabetes "Has anyone been irritable on Ozempic? I've been on it for 5 days. I've had the nausea, headache, and diarrhea, but I also feel very irritable (could be hormonal, LOL). Just curious if anyone else experienced that."

• Kom...
• Taken for less than 1 month
• November 27, 2019

Semaglutide "Oh boy. I just started Ozempic for weight loss at .25. After my first injection, I was fine for two days, and then was constipated for two days—and since then I’ve been pretty darn sick. Violent diarrhea, headaches, some nausea, and very low energy. I’ve taken several days off from work as I’ve felt so bad. I’ve lost weight since I have no appetite, and nausea follows whenever I eat—even broth and crackers. I have international travel planned in 10 days, and I hope that I’m recovered by then. I may try again after my travels, but this has been rough. The worst side effects I’ve had from a new medication."

• Ley...
• Taken for 1 to 6 months
• June 3, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "From the initial starting dose until I went up to 1 mg, the whole 6 months was a roller coaster of nausea, headaches, and uncontrollable vomiting. The nausea was always followed by throwing up 5-7 times per day. If I ate or drank anything with too much sugar (including fresh orange juice), then I would throw it up within 30 mins. The sulfate mouth smell, along with the vomiting, was difficult and embarrassing. Exhausted and tired feeling, along with feeling depressed and hating/disgusted by food, is how I felt. I did lose about 8 kgs before moving on to Saxenda. Get ready for Ozempic to destroy your life for a few months if you want to lose weight with it."

• C01...
• Taken for 1 to 6 months
• July 6, 2021

Semaglutide for Cardiovascular Risk Reduction "3 weeks in... Initially prescribed for weight management. While my appetite's drastically reduced, I've experienced headaches, some brain fog, and felt a little under the weather. Nausea slightly though it reduced day by day. Fatigue's unbearable. I typically have an upbeat, positive attitude and noticed a not-so-good version of myself just recently. Contemplating discontinuing treatment as excited as I am for the weight loss aspect of it :("

• Hop...
• Taken for 1 to 6 months
• April 22, 2022

Semaglutide for Weight Loss (Obesity/Overweight) "I started on Ozempic 12 weeks ago in Jan 2022, which is the same as Wegovy in a lower dosage. I spent 4 weeks on the 0.25 dosage, losing 2 lbs. Moved up to the 0.5 dosage for 4 weeks, losing another 2 lbs, moved up to the 1 dosage for 4 weeks, and lost an additional 3 lbs. I just took my first dose of Wegovy at the 1.7 dosage, and wow can I tell a difference. I won’t lie, I have experienced a few side effects, such as constipation, some abdominal pain, nausea, headache, and diarrhea, but all have been mostly mild and very tolerable. Nothing that can’t be helped with eating a little less. The key to managing all of it is learning how to eat properly with the right portion sizes. Only eat until you are satisfied rather than full. For me, it is well worth dealing with mild side effects in order to achieve a healthy lifestyle!"

• Ano...
• Taken for 2 to 5 years
• May 20, 2025

Semaglutide for Type 2 Diabetes "Nausea on a regular basis over two years of having it. Severe weight loss, even when not needed, as unable to face food. Blurred vision and pain in the eye. I don’t recommend it just for weight loss. I started on 0.25, going up to 0.5. Constant headache because of eye pain. I came off insulin, but am now stopping Ozempic, can’t put up with eye and headache. I would rather have insulin four times a day."

• Bra...
• March 15, 2021

Semaglutide for Type 2 Diabetes "Ozempic lowers my blood sugar. I have found in the 4 weeks I have been taking it, I have lost weight (not sure how much, but it's noticeable for the first time since I was diagnosed with type 2 diabetes 6 months ago). I am struggling to decide if it's worth being sick 2 days a week. I have extreme nausea (like I have mild food poisoning), a terrible headache, and I'm exhausted. The rest of the week, I feel fine. It is the two days following the injection that I have these awful symptoms. The first three weeks I was at 0.25, I found by week 3 they were milder symptoms, but this week I have increased to 0.50, and I am extremely sick with nausea and headache. I've found the GI issues mild, but I am on other medication that constipates me. I feel this may have been worse otherwise. I am going to tough it out for the next few weeks until I get to 1, as I found a decrease in the nausea over the first three weeks until I increased the dosage. However, if this is a constant side effect, I will 100% be discontinuing this medication."

• Hoo...
• May 17, 2018

Semaglutide for Type 2 Diabetes "Initially began Ozempic 0.25mg for 4 weeks. Side effects were tiredness, constipation. My fasting blood sugar numbers were lower in the morning. When I began the 0.50mg dose at 5 weeks, I had nausea, dizziness, and lethargy the day following the first dose. The second day following that dose, I felt about 70% better. With the second dose of 0.50mg, side effects were less severe, some minor nausea, headaches, and the tiredness continued. I hope that these side effects disappear. I plan to take this medication until I get my 3-month labs, and I expect that my A1c will be down significantly. It was at 5.9 in July of 2017. Due to the stress of caring for a dying relative from September through December, it jumped to 9.3. At my next appointment, my doctor suggested I try Ozempic in combination with Metformin 500mg twice a day. I received a 3-month discount card and have not yet checked with my health insurance provider to see if it will be covered. I am an active 61-year-old female, but type 2 diabetes does run in my mother’s family."

• Kel...
• Taken for less than 1 month
• August 20, 2021

Semaglutide for Cardiovascular Risk Reduction "Was Ozempic for 4 weeks. Giving myself a weekly injection. Week 1 and 2, I was okay. The end of week 2, I was really nauseous. By the 3rd week, I couldn't eat or drink anything. My prescriber assured me I would be okay, so I went on with my 4th week. I spent 3 separate days in A&E, and I was diagnosed with a clot in the lung (PE). Now, maybe this wasn't directly caused by the injection, but due to the severe nausea and dehydration, that is how I got a clot. The nausea still continued for 4 weeks after my last injection. I would never recommend this at all. If my clot hadn't been picked up, goodness knows what may have happened. I also had bad dizziness and severe headaches."