Ozempic and Diarrhea: What Users Say (Page 5)

• Pum...
• Taken for less than 1 month
• August 21, 2019

For Type 2 Diabetes "Endo gave me a 1-month sample for type II. Just into my second week at 0.25. Initially, upset stomach and diarrhea. Wouldn't say nausea per se, more like a stomach ache. Diarrhea wasn't crampy and prolonged like metformin. Appetite really decreased. Sugars started going down about 3-4 days in, and symptoms lessened by day 6. But.... weight gain of 3 lbs! What the...? Just on day 2 of the 2nd week, no nausea, but still eating less. Not peeing as much and waking up earlier and easier, and morning sugars down from 11-12ish to 8-9ish. I will be disappointed if I am the rare one that gains weight though."

• cra...
• Taken for 1 to 6 months
• June 24, 2019

For Type 2 Diabetes "I was okay on the 0.25 mg and 0.5 mg doses of this drug, Ozempic. Then, five weeks ago, I upped to 1 mg as planned. About four weeks ago, my mood changed, and I started to get pain in my joints and bones. Achy all over and no energy. Two weeks ago, the abdominal pains, gas, diarrhea, and those awful sulfur burps arrived. I feel absolutely awful, and the doctor is convinced it is this drug increasing. No appetite either and feeling sick. Was loving the drug in the beginning, but now I feel like I've got permanent flu!"

• MJa...
• Taken for 6 months to 1 year
• January 18, 2021

For Type 2 Diabetes "I was on Ozempic (0.5) for 11 months. I had all of the worst gastric symptoms the entire time. Constant diarrhea, constipation, sulfur burps, constant rumbling stomach, VERY loud and odoriferous flatulence, and no real control over bowel movements. I was wearing diapers so I could sleep because I was afraid I would not have time to get to the bathroom. My A1c went from 16+ to 6.6 in 3 months, so I stuck with it. However, I had lost 70 lb. before I started it - and gained back 40! I eat right and did exercise (until the gastric situation was too bad). It has taken 6 weeks, and I finally feel normal, but my A1c has shot up to 13 in that time (which means it's probably higher than that). I don't have any other chronic illness besides diabetes - no gastric issues before that."

• Bea...
• October 14, 2019

For Type 2 Diabetes "I started Ozempic at the end of July 2019. After 10 years of Metformin 1000 mg a.m. and p.m. & Januvia, the result turned into explosive diarrhea. Tried Jardiance, which resulted in yeast infections. Then Janumet, all of these with Metformin. Constipation. Started Ozempic in July, 0.5 mg with Metformin. Lost weight and appetite suppressed, but diarrhea continued. Changed to 1000 mg Metformin in a.m. & Januvia in p.m. Constipation again. Changed to 1 mg Ozempic after several months and 1000 mg Metformin in a.m. and 500 mg p.m., no Januvia. Constipation. Finally taking 1 mg Ozempic and 750 mg Metformin a.m. and p.m. works great. Bowel movements normal. My daily readings went down using Ozempic. No side effects. Lost 19 lbs. Not due for A1C until December. Love it. Went from 200 lbs to 181. Sugar cravings decreased. Feel positive. I am an active 70-year-old female. I don’t plan on taking Ozempic forever because the possible long-term thyroid side effects scare me."

• Ann...
• Taken for less than 1 month
• May 28, 2019

For Type 2 Diabetes "I took my first dose of Ozempic on May 23rd. Two days later, side effects began. My stomach started burning, frequent diarrhea, and profuse vomiting. I cannot hold anything on my stomach, and I have lost over 13 lb in 3 days. The side effects are horrible. I have contacted my doctor with hopes to get relief from the side effects! The pain is horrible. I do not recommend Ozempic!"

• Swi...
• Taken for 1 to 6 months
• May 13, 2019

For Type 2 Diabetes "Started on Ozempic 5 months ago for diabetes 2. Started at 0.25, then 0.50, now at 1.00, and so far I lost weight - 35 lbs. But I’m feeling really fatigued, dizzy, and occasional stomach ache, diarrhea, and my eyesight has changed. Great drug for lowering A1C and losing weight, but the side effects are horrible. I think I’m done taking this drug. Side effects are getting worse."

• ERM...
• Taken for less than 1 month
• February 25, 2019

For Type 2 Diabetes "This drug should be taken off the market. Side effects are severe. Belching, uncontrollable diarrhea, dehydration, nausea, vomiting. Be prepared to not leave your bathroom for 3 days every week. Not to mention, the ads are by far the most annoying on TV."

• SAL...
• Taken for 1 to 6 months
• June 26, 2019

For Type 2 Diabetes "Been on Ozempic since March 2019, started off with 0.25, then 0.50, then to 1 mg. Side effects: nauseous, constipated, with fever. One month into taking Ozempic, started to have blood in my urine, no infection, CT, blood clots, bladder scope, bladder okay. CT with contrast upcoming to check kidneys, and my urine tests are concerning the PA. When giving the shot, medicine would make a bubble under the skin, then welt up 1 inch wide, 3 inches in length, and at least a .5 inch depth, 36 hours later with high fever, diarrhea, stomach cramps, large amounts of blood clots in urine, 3 times. Called Ozempic, which requested the medication back and sent a voucher for a new script. I have been taking this for 4 months, note I am not a doctor, just concerned, so I believe this could be a drug that has not been fully evaluated and may not have full understanding, or it's an odd situation for myself. However, these symptoms did not show up until on Ozempic. So for my own health, I have opted not to continue this drug."

• Tja...
• Taken for 1 to 6 months
• June 9, 2018

For Type 2 Diabetes "My Dr. prescribed Ozempic for weight loss after I lost 50 lbs using Trulicity. I had few side effects from Trulicity. My side effects from Ozempic are awful. Two to three days after a weekly dose, I experienced severe diarrhea, gas, belching, nausea, lasting about 24 hours. I stopped injecting it for a couple of weeks, then tried it again to confirm Ozempic was the cause. It is. I learned my lesson."

• mnd...
• Taken for less than 1 month
• March 14, 2019

For Type 2 Diabetes "Has anyone been irritable on Ozempic? I've been on it for 5 days. I've had the nausea, headache, and diarrhea, but I also feel very irritable (could be hormonal, LOL). Just curious if anyone else experienced that."

• Eda...
• Taken for 1 to 6 months
• February 6, 2020

For Type 2 Diabetes "So I have been on Ozempic for 5 weeks. I am tired a lot. Not sure if this is the drug or my poor sleep, but now that I see others are tired a lot, it makes me wonder. I have nasty burps a lot. I started on a dose of 0.25 for 4 weeks. I had a lot of low-level nausea, but not too bad except for one day. Then last Sunday, I took the higher dose of 0.5, and I was okay on Sunday and Monday, but Tuesday the nausea was horrible, and I had explosive diarrhea all day to the point I had to take Imodium, and I got my doctor's office to prescribe an anti-nausea med, Zofran, which helped a little. The next day, less nausea, and today is Thursday of that week, and I still have the burps and more BMs than I would like, as well as a lot of gas. I know I have lost weight just by how my clothes fit. I have very little appetite. Not sure if the pluses outweigh the minuses yet. I am probably going to try one more week and see how I feel. It has had a modest impact on blood sugars. I have been using less insulin."

• Bai...
• Taken for less than 1 month
• July 3, 2019

For Type 2 Diabetes "At first, I had a brief overwhelming bout of nausea that passed. Decreased appetite definitely had me losing weight, but after the second injection, the nausea got much worse! Plus, I had diarrhea/vomiting, and it just got worse daily. I had to discontinue. Now it's been a month later, and I'm still having nausea and diarrhea. Horrible experience for me."

• Tes...
• Taken for 1 to 6 months
• May 14, 2023

For Type 2 Diabetes "So I began Ozempic just a few months ago. Just took my first 1 mg dose last week, and I have to say, I am sick all the time. Anything I eat is for sure going to end up in the toilet one way or another. The diarrhea is out of control and constant. When I was only on the 0.25 mg dose, I had a window of the day where I was actually able to eat and not vomit it up later, but since going all the way up to the 1 unit, I cannot keep anything down. I have two small children, and I feel exhausted all the time from the vomiting and the nausea. I have decided today that I will discontinue this medicine as I cannot deal with the severe side effects. Even Zofran isn’t working."

• PDH...
• Taken for 1 to 6 months
• June 21, 2019

For Type 2 Diabetes "I started Ozempic about 3 months ago at .25 mg. My doctor made me start my 1st dose on a Monday in her office because I would tell her I would try and then never do it. Tuesday morning I was good, then by Tuesday night, stomach cramps, nausea, vomiting, and diarrhea, till the wee hours of the morning. The symptoms slowed down throughout the week. Even though I was losing at least 3-4 pounds a week, a total of 35 pounds within a 2 1/2 month period. My A1C did go down, the side effects are deadly. I like the fact that I am losing weight, but I hope I don't have permanent damage from this medication."

• Nom...
• Taken for 1 to 6 months
• April 23, 2021

For Cardiovascular Risk Reduction "Sulfur burps, sulfur farts, abdominal pain, diarrhea, bloated, pancreas pain, sore breasts, feeling as if I am going to faint, pressure behind eyes. I have never been to the hospital so many times in my life. They told me I had a 'stomach bug', turns out that it was Ozempic. I had such high hopes, I've heard many great things. User beware!"

• Kom...
• Taken for less than 1 month
• November 27, 2019

"Oh boy. I just started Ozempic for weight loss at .25. After my first injection, I was fine for two days, and then was constipated for two days—and since then I’ve been pretty darn sick. Violent diarrhea, headaches, some nausea, and very low energy. I’ve taken several days off from work as I’ve felt so bad. I’ve lost weight since I have no appetite, and nausea follows whenever I eat—even broth and crackers. I have international travel planned in 10 days, and I hope that I’m recovered by then. I may try again after my travels, but this has been rough. The worst side effects I’ve had from a new medication."

• Ang...
• December 11, 2019

For Type 2 Diabetes "It was good on low dosage 0.25, but after 2 months, it loses effect, and you need to increase the dose. Still fine, I lost 30 pounds, but then you have to increase the dosage, and that's when I got stomach aches and diarrhea, and I had to stop it."

• Nes...
• Taken for 1 to 6 months
• May 3, 2019

For Type 2 Diabetes "Was diagnosed with type 2 diabetes in March 2019. Doctor put me on Ozempic rather than insulin, although it's not recommended. He thought it was worth a try along with 500 mg metformin twice daily. The first 3 weeks of 0.25 mg Ozempic were just fine. Very minimal side effects - occasional diarrhea, some gas, and belching. Nothing I couldn't handle. The fourth week of 0.25 mg was worse. Constant diarrhea for four days, nausea, some vomiting. I went to a different doctor thinking I had a stomach virus, he prescribed me an anti-diarrheal, and I felt better. I took the Ozempic at 0.5 mg then, as prescribed. Two days later, nightmare. Diarrhea again, vomiting, nausea, and serious fatigue. I'm in the throes of it right now, and I'm going to be contacting my doctor to see what I can do to counteract this. Besides the side effects, though, it's working beautifully. My blood sugar is down from the high 300s to the low 100s in just a month."

• Nen...
• Taken for less than 1 month
• May 1, 2019

For Type 2 Diabetes "I have been taking Ozempic for 3 weeks. At .25. My hunger is gone! Before, all I ever thought of was food. Now I am full with about half of what I serve on my plate. I am not eating between meals. I get some nausea but not severe and some diarrhea often. No yucky burps! I am losing weight."

• Ric...
• Taken for 6 months to 1 year
• March 5, 2025

For Type 2 Diabetes "I've been on Ozempic for nearly a year. My doc eased me into it, and I plateaued at 1. Recently, I've gone to 1.5. I also discontinued Glicklazide. I've now lost enough weight that people are noticing. We'll see what the upcoming A1C test shows. But something is giving me bad diarrhea off and on. Sometimes a meal races right through me. It might be an interaction with other meds and supplements or even particular foods. I can't see a pattern."

• Nuk...
• Taken for 1 to 2 years
• December 13, 2019

For Type 2 Diabetes "I've been on Ozempic for a year. Taking 1.0 mg. Pros: Have lost 40 pounds. A1c went from over 8 to 6.2. Have stopped taking insulin and glyburide. All positive. Cons: Days of constipation followed by hours of diarrhea. No appetite. Cost is way out of control. But I'm satisfied enough that I'm still on it."

• JTa...
• Taken for 1 to 6 months
• June 14, 2019

For Type 2 Diabetes "Started out taking 0.25 for 4 weeks, then the 5th week went to 0.50. The next day I was vomiting, had diarrhea, and sulfur burps. Couldn't hold anything down, not even water. Went to the ER the 2nd day to get IV fluids. Called the manufacturer and put in a report. They sent me a mailer to return the pen for evaluation. I am keeping a record of the lot # before I mail the pen back. I am taking a nausea pill and experiencing severe cramps and diarrhea, but the vomiting has stopped. Haven't had any solid food for 4 days, trying to eat Jell-O and applesauce and can barely get it down. So wished I would have read these reviews before I bumped it to 0.5. My diabetes doctor said to decrease. I am going to stop taking it. I have no spleen, so it is difficult to manage all these side effects. Hoping and praying I can start to feel better soon."

• I...
• Taken for less than 1 month
• November 1, 2021

For Type 2 Diabetes "I rarely ever have side effects from any drugs that I have taken before. After my second dose, I began extreme side effects of stomach pain, bloating, sour belching, flatulence, diarrhea, zero appetite, and indigestion. These symptoms have not gone away after 10 days of discontinued use. It definitely lowered my daily sugar levels. You can use this medication if you are okay with feeling like death."

• Car...
• Taken for 1 to 6 months
• March 2, 2025

For Type 2 Diabetes "1st week stomach discomfort (not too bad). 2nd week flatulence (sudden, uncontrollable, embarrassing). 3rd week sore throat, lots of phlegm, hard to swallow! 4th week, no appetite at all! Sudden diarrhea, no control, running out of me like water! I’m experiencing back pain in between my shoulders! Headache! 8-9 in pain! 10 excruciating!"

• sil...
• Taken for 1 to 6 months
• March 24, 2019

For Type 2 Diabetes "I've been on 1 mg of Ozempic for about 8 weeks and lost 13 pounds. My appetite has decreased. Other people started out at .25 or .5, I've noticed from reading other reviews. Considering this, I'm shocked my doctor started me on 1 mg. I was really sick the first month. Lots of vomiting, gas, stomach ache, and diarrhea. Despite all that, I'm pleased that I lost weight and the side effects have gone away. I just hope it continues to work as an appetite suppressant. Other meds I've taken that were originally one for me stopped working on my appetite after a while."