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Semaglutide for Weight Loss (Obesity/Overweight) User Reviews (Page 5)

Brand names: Ozempic, Rybelsus, Wegovy

Reviews for Semaglutide

Commonly mentioned side effects
  • Hel...
  • March 17, 2022

Semaglutide "I can’t figure out how to live with this drug without feeling sick or vomiting. Zofran helps, as does not eating. Then I try to eat what seems like a small amount of food, and I’m sick. This sucks, but my last resort!"

2 / 10
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  • Shi...
  • Taken for 1 to 6 months
  • September 15, 2024

"Only lost 10 lbs in 5 months. Used once a week by injection from April through August 2024. Having hair loss!"

3 / 10
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  • Hel...
  • Taken for 1 to 6 months
  • July 2, 2024

Semaglutide "Started with 0.25mg, very easy, full instructions, separate pens for each dose increment, so foolproof. The nausea started within a couple of hours of the first injection, over the first month the nausea was pretty constant all day but eased off after around 5 days so 2 days with minimum nausea, however within 1 hour of 0.5mg dose nausea was worse and no let up, was actually sick on 1 day and felt like I would be sick in the second week. After 2 weeks on 0.5mg decided I could not continue to feel unwell ongoing. Weight loss was minimal, less than 1lb per week with 'careful' eating choices although not fully dieting but think you have to be very determined to tolerate the nausea."

3 / 10
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Frequently asked questions

  • Brf...
  • Taken for 1 to 6 months
  • July 17, 2023

Semaglutide "Taking for BMI over 32%, weight reduction. Started weighing 220 lbs. Currently at 1.7 mg dose, with 2 weeks remaining. Since starting, I have lost 20 lbs. However, I will be discontinuing Wegovy due to the intolerable side effects. Ended up in the ER for vomiting, diarrhea, and flu-like symptoms. They gave me fluids, anti-nausea and cramping meds. That was around 24 hours ago and while I can keep liquids and soup down initially, I end up vomiting then uncontrollably retching hours later. It's been near impossible to eat healthy or at all, with a lack of appetite and a sudden aversion to the smell and taste of certain foods. I regret not giving my energy to a healthier lifestyle and am wondering how long it will take for the Wegovy to leave my system. Please take all side effects into consideration before taking."

3 / 10
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  • Mim...
  • Taken for 1 to 6 months
  • July 7, 2023

Semaglutide "Since my first injection, I have felt utterly dreadful. The nausea is one thing, but I have constant fatigue that prevents me from leading my normal life. I know it suppresses appetite, but I don’t have ANY appetite at all and cannot face food. I know if I eat, I will feel a bit better, but it’s impossible. I actually feel like I’ve been drugged. Yes, the ‘food noise’ has gone, and I no longer overeat or binge, but I feel like everything is suppressed - like I’m on a strong drug. I did 4 weeks at 0.25 and have just done one week at 0.5, but I can’t do this anymore. I feel utterly dreadful. I am so pleased it’s helping so many people, but more research is needed into why some people just can’t tolerate it."

3 / 10
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  • Kar...
  • Taken for 1 to 6 months
  • June 29, 2023

Semaglutide "Been on Ozempic for 6 weeks and haven't lost any weight. I have been dieting along with Ozempic, but can't seem to lose this weight. I will stick with it another 4 weeks and see what happens."

3 / 10
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  • Arc...
  • Taken for less than 1 month
  • May 31, 2023

Semaglutide "I just started on May 1st at 0.25 mg, and so far, there has been no change in my weight. I'm still in the same range I was before starting (i.e., 245-250 lbs). I still feel hungry during certain periods of the day. I try to eat fruit, etc. It may be early, so I am hoping the next dosage or the one after will help with the hunger. I have changed my diet and eat a plant-based diet with a lot of fiber."

3 / 10
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More FAQ

  • Joe...
  • Taken for 1 to 6 months
  • May 30, 2023

Semaglutide "Side effects of nausea and vomiting. 0.5 mg doses are on serious back order, so went to 1 mg dose. No longer taking due to side effects."

3 / 10
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  • ACD...
  • Taken for 1 to 6 months
  • May 27, 2023

Semaglutide "I have experienced severe gas, belching, flatulence, moderate nausea all night, not heartburn but feels like seasickness, and moderate constipation. Have had about a 7-pound weight loss in a month. Simple to use with no problems injecting or at the injection site."

3 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • May 24, 2023

Semaglutide "Easy to administer, but during the first few weeks, had zero weight loss. Dose was increased. Woke in the middle of the night after the last dose with severe heartburn. Vomited every four hours for two days. Missed a day of work. Not able to keep anything down, including water. Put on anti-nausea medication. Have to sleep in a sitting position and take antacids and prescription meds to control heartburn enough to sleep. Cannot wait for the medication to get out of my system so I can function without vomiting or constant heartburn."

3 / 10
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  • Pat...
  • Taken for 1 to 6 months
  • May 22, 2023

"No weight loss, the pen leaks most of the medication out, so I don't get the full effect of the med. This is the third injection, and all three have leaked out."

3 / 10
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  • Jus...
  • Taken for less than 1 month
  • May 13, 2023

Semaglutide "I started Ozempic .5 mg once a week. I have taken it for 3 weeks. I have had to stop it because I have been so sick. I have had massively bad headaches, nausea, vomiting, and stomach pain. After the first injection, I ended up in the ER because of my stomach pain, and then again 5 days later. I haven't been able to keep anything down. I can barely keep 2 sips of water down. I can't even take any of my prescription medications because I am constantly throwing them back up. My doctor told me to stop taking it. My husband says I've lost weight, but that's only because I'm constantly throwing everything up."

3 / 10
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  • Lyn...
  • Taken for less than 1 month
  • May 10, 2023

Semaglutide "I haven't noticed much weight loss with this medication. I have experienced extreme nausea to almost vomiting. I have also suffered from daily headaches from this medication. I have also noticed my blood pressure fluctuates higher than my normal high. I am only on the 1.0 mg dosage right now, and my doctor will increase it next week. I do have to say the pens are very easy to use, and the needle injections don't hurt."

3 / 10
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  • Anonymous
  • Taken for less than 1 month
  • May 1, 2023

"A horrendous coughing fit led to a pulled neck and intense pain. 10 days of reflux meds, painkillers, antibiotics, and steroids to resolve it, but had to miss work. It was an effective appetite suppressant. Unfortunately, when I requested a half-injection, I was told it would not work."

3 / 10
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  • Dee...
  • Taken for 1 to 6 months
  • April 10, 2023

Semaglutide "I wish I did more research before starting this. I started on Saxenda and worked up to 3.0 mg, the max dose. I had a few bouts of severe diarrhea and vomiting. I lost a total of 15 pounds and then started getting ravenous. Then I got switched to Wegovy 2.0 mg and then moved up to 2.4 mg. I only had a couple of incidents of terrible nausea, usually when I ate greasy, heavy, or fried foods. But generally, I feel like crap every day. Once on the Wegovy, the weight literally fell off. Mostly because I just didn't think about eating anything, or my appetite would be satisfied with a very small portion of food. The biggest side effect is skin irritation; like a constant sunburn. Clothes touching my skin bother me. Or riding in a car and bouncing. It became intolerable. And chills make my skin ache. I easily surpassed my goal weight and now trying to decide if I want to quit it altogether or reduce the dosage and hope the skin irritation goes away."

3 / 10
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  • Jji...
  • April 2, 2023

Semaglutide "Awful. I felt tired and like I had morning sickness the whole time. Was on one month of .25 mg and two months on .5 mg. It never got better. I was constipated and on the verge of throwing up constantly. Also started post-menopausal bleeding despite being on HRT. All of this, and I only lost a whopping 9 pounds despite barely being able to eat even cereal. Your diet turns to garbage because you just stick to stuff that won’t make you feel more nauseous. You will not learn how to eat properly; just how not to eat foods that make you throw up. I just switched to phentermine, and I’ve already lost two pounds in 5 days. My energy is back. Zero side effects and less than $15/month. Read the long-term reviews, people. Unless you are going to stay on this for life, which I would never do seeing how it messed with my hormones, you will 100% gain it all back and then some."

3 / 10
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  • Vee...
  • Taken for 1 to 6 months
  • March 25, 2023

"Totally took away my appetite. I no longer eat breakfast or crave certain foods/snacks. Gave some foods a 'metallic' taste. Makes me feel fuller. I had no side effects."

3 / 10
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  • Tou...
  • Taken for less than 1 month
  • March 14, 2023

Semaglutide "I am on my 3rd 0.25 dose of Wegovy. I feel terrible most of the time. I have lost 5 lbs and am definitely not hungry due to nausea. My prescriber will not prescribe Zofran with Wegovy because she feels nausea that severe should be considered a negative side effect and the medication stopped. That's reasonable. I read the reviews before I began the med and take Omeprazole daily, as well as Miralax. I am 57, menopausal, and used to feel really good most of the time. Sadly, this med is not worth the side effects for me. I really, really wanted to tough it out, but as a nurse, I feel it's creating problems that I did not have before taking this medication. The nausea is constant, the belching/burping is so frequent that it's embarrassing, stools are like a rock, and the worst feeling is chest tightness. I had so hoped I would be one of those without adverse side effects, but I am not."

3 / 10
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  • Ter...
  • Taken for 1 to 6 months
  • March 12, 2023

Semaglutide "After two doses of 0.05 mg, I started having shortness of breath. So bad that I wasn’t able to do anything with exertion involved. While grocery shopping, I almost passed out. Although I have lost 16 lbs, I am going to stop taking the medication."

3 / 10
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  • Mel...
  • Taken for less than 1 month
  • March 9, 2023

Semaglutide "Week 2: I have not had any appetite suppression, just very bad constipation. I've had to take stool softeners with every meal and use glycerin suppositories to unplug my colon. No weight loss yet."

3 / 10
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  • Mic...
  • Taken for less than 1 month
  • November 11, 2022

Semaglutide "Horrible! Spent 24 hours in the ER with severe nausea and vomiting! Needless to say, I have 3 doses left if anyone needs!"

3 / 10
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  • Ter...
  • Taken for 6 months to 1 year
  • August 23, 2022

Semaglutide "I've been taking Wegovy for about 8 months, and I've lost about 40 pounds. My problem is finding a pharmacy that has it in stock. I'm taking 2.4, and it has me throwing up and feeling nauseous all day. I would love to go back to 1.7, but I can't get my insurance to authorize it. I'm not going to take the 2.4 anymore because it's too strong. Now I have 2 boxes I can't use. This sucks."

3 / 10
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  • Van...
  • August 4, 2022

Semaglutide "Expensive and worthless. I got extremely nauseous for days, unable to eat, and felt like I’d collapse from weakness, but I had no appetite."

3 / 10
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  • Car...
  • Taken for less than 1 month
  • July 25, 2022

Semaglutide "I am on my second week. First week (day after shot) I got severe nausea and dry heaving. I was so exhausted and zero energy. My depression got way worse. Second week the same. I don’t think I will continue, but I signed a contract, and I was told I can cancel at any time, but it looks like this is going to be a problem. This has been a wake-up call, and the nausea has taught me a lesson to never eat bad foods again and really focus on portion control. The side effects aren’t worth any weight loss in my opinion!"

3 / 10
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  • Hai...
  • May 12, 2022

Semaglutide "Helped me lose weight. But the hair loss was extreme. I only needed to lose 15 pounds to get to my goal. But I had the extreme hair loss. I had tests done, and hormones and thyroid profile all normal, there was no other explanation. Hope it grows back."

3 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.