Skip to main content

Semaglutide for Weight Loss (Obesity/Overweight) User Reviews (Page 4)

Brand names: Ozempic, Rybelsus, Wegovy

Reviews for Semaglutide

Commonly mentioned side effects
  • Drd...
  • August 26, 2021

"I have been on this medication for two doses (0.25 mg) only and will not be continuing. Was taking it to help lose the 20-30 lbs that I need to lose and have never been sicker. The first week it made me feel slightly nauseous after eating. No matter what I ate or how much. Hours after the second dose, I started with the worst and most violent diarrhea I’ve ever had. Up all night for the fourth night last night and cannot stay out of the bathroom. Horrible stomach cramps and I’m dehydrated from the constant bathroom use. Beware…if you’re not diabetic, this drug might wreck havoc on your life. The rest of my doses are going in the trash. Just hoping these side effects pass after this week is up. It’s awful."

1 / 10
Was this helpful?YesNo
13 Report
  • Fra...
  • Taken for less than 1 month
  • July 23, 2021

Semaglutide "This shot made me so sick for 3 days. I have never been so nauseous in my life. Threw up the 1st morning after taking it. Never use it again."

1 / 10
Was this helpful?YesNo
25 Report
  • Ang...
  • Taken for 1 to 6 months
  • July 22, 2024

Semaglutide "I started on 0.25 Wegovy. The injections are painless and easy to administer. For the 4 weeks, I took this dose, I felt fine with little side effects. I lost 3 lbs. I then moved onto 0.5 dose. I took the dose on a Friday and woke in the middle of the night with terrible sudden reflux and vomiting. This happened for 3 nights. I took my next 0.5 dose the following Friday and the same happened, along with dizziness, constant nausea, and very low mood. I have decided not to take the last 2 injections I have left as I just feel so poorly."

2 / 10
Was this helpful?YesNo
9 Report

Frequently asked questions

  • Anonymous
  • Taken for less than 1 month
  • January 5, 2024

"I was only able to use 1 injection of semaglutide, the side effects hit me so bad that I couldn’t continue the medication. I got the injection on a Friday, and 2 days later, I had a seizure, which I ended up in the hospital. I had no appetite at all, but the constant headaches and nausea were too much."

2 / 10
Was this helpful?YesNo
0 Report
  • Anonymous
  • Taken for 1 to 6 months
  • June 21, 2023

Semaglutide "I have lost 37 lbs in 3.5 months, but should be more due to the horrific side effects. Burping, belching, vomiting, diarrhea, chest pain, nausea, blurry vision, basically every side effect imaginable. I never had side effects from any medications before. I continued to increase the dose up to 1.7 mg and hope for the best with no success. I have three more weeks of misery, but due to the cost of $586, I refuse to trash this medication."

2 / 10
Was this helpful?YesNo
7 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Xim...
  • Taken for less than 1 month
  • June 19, 2023

Semaglutide "I started taking Wegovy one week ago. I have had 2 injections of 0.25 mg. It feels like I have never been this sick before. Terrible cramps and diarrhea since day 3. I have heard about side effects, but I was stubborn and wanted to try. I regret doing it. I learned my lesson. Needless to say, I will stop the treatment. I am sure I have lost some weight. I am not retaining any food. A few minutes after eating, I have to go to the bathroom. I am glad to hear it has worked for many people. This medicine is certainly not for me."

2 / 10
Was this helpful?YesNo
6 Report
  • lee...
  • Taken for less than 1 month
  • June 15, 2023

Semaglutide "This is my second week on Wegovy. During the first week, I felt fine, but this week, I am experiencing extreme fatigue, tachycardia, headache, and craving sweets. I find myself not eating anything other than meat and no sides. I think I might be done with it. I don't like feeling like this. It's just the second week, and I can't imagine what the third week would feel like."

2 / 10
Was this helpful?YesNo
2 Report

More FAQ

  • Anonymous
  • Taken for 1 to 6 months
  • June 2, 2023

Semaglutide "I started at 173 lbs and have taken the third injection of the second pack dosage. My weight today is 168 lbs. I have not had any of the side effects. It has not controlled my hunger. I hope I will see a difference when I start the third packet dosage next week."

2 / 10
Was this helpful?YesNo
2 Report
  • BJB...
  • Taken for 1 to 6 months
  • May 20, 2023

"I started using semaglutide for weight loss at the lowest dose, and each 4 weeks raised the dosage. I did not lose a single pound in all that time. I am a yoga instructor and practice 4 times per week. I became so severely constipated that I ended up in the ER. I battled with very severe fatigue, weakness, at times overly hungry, blurry vision, and a feeling of just being 'out of it.' I feel like I lost 3 months of my life. After taking my last dose 9 days ago, I’m still having bouts of diarrhea, stomach pain, and headaches. It was not worth it at all for me."

2 / 10
Was this helpful?YesNo
1 Report
  • All...
  • Taken for less than 1 month
  • May 19, 2023

"I have lost 25 pounds on my own in the last 3 months and decided to give compounded semaglutide injections by my doctor a try to give me a helping hand. On 5/16/23 at 9 a.m., I had my first injection in my arm, and I instantly got a slight headache. By 2 p.m., I was severely nauseated and had to leave work early. Stayed that way all night, and my mouth was watering so bad I was standing over my sink for hours. My stomach was bloated and stayed that way for the next day. On days 2-4, food smelled so bad it made me nauseated. I didn't eat anything but toast. Nothing carbonated could be tolerated at all, or sweet, or cooked for that matter. But the worst part was the nonstop diarrhea and severe stomach cramps. I won't be taking this again. Ex-Lax is a lot cheaper! I hope this wears off soon. Not for me. Kudos to those who have no side effects or could stick it out. I can see why this has been so effective for weight loss (food looks and smells disgusting), but the sickness is unbearable to continue and I can't miss any more work."

2 / 10
Was this helpful?YesNo
1 Report
  • Kay...
  • Taken for 1 to 6 months
  • May 18, 2023

Semaglutide "I’ve been on Wegovy for 3 months and have gained 2 lbs. I have had side effects such as severe constipation, fatigue, and issues with my menstrual cycle. I am glad other people have had positive experiences with this drug, but it’s definitely no miracle. I decided I can make healthy changes without this medication. I stopped using it."

2 / 10
Was this helpful?YesNo
5 Report
  • JDF...
  • Taken for 1 to 6 months
  • May 13, 2023

Semaglutide "I started on the 0.25 mg, then increased to 0.5 mg and now on 1.7 mg. So far, I have not lost any weight and have been queasy almost the entire time. I have been using the relief band to help with the queasiness. I do not eat as much as I did before I started, plus I don’t drink alcohol hardly at all now. Besides that, I am not sure of the benefits yet. I will try it for another dose increase to see if it works. If it doesn’t, I am going to stop taking it."

2 / 10
Was this helpful?YesNo
4 Report
  • Sum...
  • Taken for less than 1 month
  • May 11, 2023

Semaglutide "Never again! I have been taking this for 4 weeks now along with 3 family members, and we all say the same thing. We feel exhausted. I’ve never felt so tired in my life. My son, who’s so fit but has always struggled with his weight, runs several miles a day and is struggling with tiredness too. If I take it on a Sunday, by Wednesday I could sleep standing up. Be warned."

2 / 10
Was this helpful?YesNo
29 Report
  • Anonymous
  • May 6, 2023

"I am on my second day, and I feel like I'm going to meet my maker. I'm extremely nauseous and tired! I haven't eaten these last two days. I'm hoping it will get better. Will keep you posted."

2 / 10
Was this helpful?YesNo
2 Report
  • Bpm...
  • Taken for less than 1 month
  • April 22, 2023

Semaglutide "After being on another weight loss drug for 6 months and losing 35 lbs, my PCP and I decided to try Wegovy. I am currently on 0.25 mg and on my fifth day. After the third day, I have been experiencing gas and diarrhea. Nothing that can’t be handled, in fact, it has started to subside. My only concern is that it doesn’t seem to curb my appetite. I had bariatric surgery in 2015, so I don’t have a huge appetite, but am worried that the current dose of 0.25 mg of Wegovy that I am currently on is not working. I am hoping it will take a few days to kick in."

2 / 10
Was this helpful?YesNo
0 Report
  • Not...
  • Taken for 1 to 6 months
  • April 4, 2023

Semaglutide "I've been on Ozempic for 4 months. Recently raised my dose to 0.75 mg, but I am stopping this medication. Yes, I lost 15 lbs, but suffered with the worst sulfur gas, was sick in bed at times, missing appointments because I felt that way. Yes, it makes you eat way less, I was never hungry but made myself eat because I had to. It gave me constipation, so I had to take stool softeners and increase fiber. Now that I stopped, I get diarrhea two days later. This medication sucks for me anyway... and from the sounds of it, many other people also. Beware!"

2 / 10
Was this helpful?YesNo
5 Report
  • Ell...
  • Taken for 1 to 6 months
  • March 30, 2023

Semaglutide "No weight loss, no appetite loss after 5 weeks. Disappointed."

2 / 10
Was this helpful?YesNo
3 Report
  • FMC...
  • Taken for less than 1 month
  • March 27, 2023

Semaglutide "I'll be taking my third injection in a moment. I honestly feel like it's not doing anything for me, but I don't know if it takes time, so I'm trying to at least allow it to produce results through the four-pack of shots I have. Halfway through, though, not impressed at all. Very disappointed."

2 / 10
Was this helpful?YesNo
2 Report
  • Anonymous
  • Taken for less than 1 month
  • March 18, 2023

Semaglutide "The prescription was $1,600.00. My insurance covered $200.00. I couldn’t pick it up. $1,400.00 every 30 days was cost prohibitive."

2 / 10
Was this helpful?YesNo
5 Report
  • Don...
  • Taken for 1 to 6 months
  • March 13, 2023

Semaglutide "I have had severe nausea and stomach pains, constipation, and back pain. Have had to stop taking it."

2 / 10
Was this helpful?YesNo
4 Report
  • Vel...
  • Taken for 1 to 6 months
  • February 23, 2023

"Started in December 2022 and on a compounded version, and to date have lost maybe 5 lbs. It's hard to tell as I am constantly bloated, constipated, and have gas pains, terrible heartburn, nausea, and feel really tired. I have experienced these side effects from the first 0.05 dose up to the 2.4 that I am on now. I am weaning myself off of it as it is not beneficial to me."

2 / 10
Was this helpful?YesNo
4 Report
  • car...
  • Taken for 6 months to 1 year
  • February 16, 2023

"I got shots for almost a year and barely lost 2 lbs. My system must be different because after knee replacement surgery, none of the pain meds worked at all. They told me I had hyperalgesia (feel pain twice as much as others). So I'm not sure if that has anything to do with it, but I was very frustrated. It often made me pretty sick too. They want me to continue, but it's pretty expensive, and for 2 lbs, not sure it's worth it."

2 / 10
Was this helpful?YesNo
1 Report
  • Ton...
  • Taken for 1 to 6 months
  • December 22, 2022

"I am on week 9, which is the 1.0 unit dosage. I'm disappointed for multiple reasons. I've been EXTREMELY constipated, which is a horrible feeling. I've taken apple cider vinegar, Mag 07, and Miralax, but afterwards constipation returns. I've been gassy, bloated, and have not lost a single pound, keeping in mind I work out 1-3 times a week. I have also experienced backaches, headaches, and a little nausea. I don't think the side effects are worth it since results can clearly vary, since I haven't had any success. I'm not going to continue with the medication anymore."

2 / 10
Was this helpful?YesNo
2 Report
  • Sar...
  • Taken for less than 1 month
  • April 10, 2022

Semaglutide "Made me terribly sick. Took only 0.25 dosage one time, had terrible diarrhea, extreme exhaustion, and some nausea. Definitely not taking the second dose. Not worth the pain. Did not lose any weight either. It stops you from eating because it makes you feel so bad if you do. I also think this drug is meant for someone who doesn’t live an active lifestyle. I work out all the time, I eat healthy, and really just wanted to drop 15 lbs. This drug was very disappointing."

2 / 10
Was this helpful?YesNo
18 Report
  • Anonymous
  • March 26, 2022

Semaglutide "I have been on Wegovy for a little more than 3 months. I have lost only about 6 lbs. I exercise almost every day and have cut out a lot of unhealthier foods. I am so frustrated."

2 / 10
Was this helpful?YesNo
8 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.