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Semaglutide for Weight Loss (Obesity/Overweight) User Reviews (Page 3)

Brand names: Ozempic, Rybelsus, Wegovy

Reviews for Semaglutide

Commonly mentioned side effects
  • Gma...
  • Taken for less than 1 month
  • August 17, 2022

Semaglutide "I was given the max dose first, which was a huge mistake. It’s been 7 days of vomiting, weakness, headaches. Still can’t eat anything. This medication is very scary."

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  • KCI...
  • Taken for 1 to 6 months
  • August 11, 2022

Semaglutide "The auto injector is awful. It would seem easy, push firmly down, wait for the clicks, count to 10. When I’ve tried pushing into my abdomen and keeping a firm surface, I damn near feel like I’ve pushed 3 inches into my abdomen and the device never engages. When it does, the medication spills down my stomach. When I switched to my thigh, again, you have to push so damn hard to get it to work. It is awful. I asked my doc to take me off Wegovy and try another product."

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  • Bec...
  • Taken for less than 1 month
  • August 10, 2022

"Taking for weight loss. After first injection (0.5) had horrible migraine. Which I’m prone to, but I also had severe nausea and acid reflux. Took my second dose yesterday (1) and ended up throwing up anything I tried to eat, been extremely nauseous today. My goal is 40 lbs, but I’m not sure I’m going to continue, I can’t function with all the nausea. I’ve lost 3 lbs, but I’m not sure it’s worth it."

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Frequently asked questions

  • Anonymous
  • Taken for less than 1 month
  • July 29, 2022

"I took 2 injections. First injection, nausea by day 2-4, diarrhea day 3-5. It does curb appetite. I also had my anxiety increase (not sure if because my system was upset, but it increased). Second injection - severe nausea day 1-3, vomiting day 1-2, diarrhea day 3-5, crying/anxious day 3-5. Once again, curbed appetite. I will be discontinuing the drug. Not for me at all. I tried it, and that’s all. But I do have Hashimoto’s, and my body is always sensitive to new meds."

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  • Bob...
  • Taken for less than 1 month
  • July 23, 2022

Semaglutide "Horrible experience after taking just the first dose. I’m going on my third week of being out of work. I have never been this sick. Violently vomiting one hour after my first and only dose. Heartburn, no energy, brain fog, couldn’t even speak coherently for the first 48 hours after taking. This stuff is like poison. Do not take it."

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  • Gab...
  • Taken for 1 to 6 months
  • July 9, 2022

Semaglutide "Horrible, I had smelly sulfur burps and nausea at 1.7 mg. After the 2.4 mg limit, I became violently ill for two days. It was projectile from both ends. Very embarrassing. After that, just constant diarrhea for days. Throw it in the garbage."

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  • LAD...
  • Taken for 1 to 6 months
  • July 4, 2022

Semaglutide "I took Wegovy for a few months and did, in fact, lose some weight. The side effects are terrible, as so many others have noted here. One thing that they don’t tell you is that the drug slows down the stomach's ability to empty. This is why people feel full and experience reflux, nausea, etc. In my case, the drug not only slowed down my stomach's ability to empty, it permanently paralyzed my stomach muscles, a condition called gastroparesis. The only remedy was to have a neurotransmitter implanted in my stomach, which forces the muscles to move. Do NOT take or first this medication. You could end up like me with a lifetime medical issue. No weight loss is worth that."

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More FAQ

  • OR ...
  • Taken for 1 to 6 months
  • July 3, 2022

Semaglutide "I lost 75 lbs on Wegovy. It wasn't worth it. People assume I have all this energy now. I feel like a shell of my former self. Run down, no appetite... and just got back from the hospital since I didn't have a bowel movement for almost 2 weeks once I was at the 2.4 dose. I can't recommend this drug. You will essentially give up your normal life to lose weight. To me, the benefits don't outweigh the risks."

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  • Pat...
  • Taken for less than 1 month
  • June 24, 2022

"This was the worst medication I have ever taken. I was sick, literally so sick to my stomach I could not concentrate. I lost 3 days of work and was not given anything by the weight loss center for the extreme nausea. I also had side effects of headaches, my BP rose to a point it has never been, I felt so weak and tired, looked like death, I had no color in my face. I literally have a cast iron stomach and nothing ever bothers me, this, however, was a pure nightmare. It is not worth taking for losing a few pounds, please stay away from this drug. I had to literally stay as still as I possibly could so I would not throw up. For whatever reason, I even lost my taste, and it has been 10 days. I just can't say enough bad things about this medication. I am just a regular mom trying to look my best and thought this would help, however, this is one of the biggest mistakes I have ever made and I still regret it. Please think twice before you inject this into your body, I wish I had done more research. Hopefully, I can help someone else."

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  • Sca...
  • Taken for 1 to 6 months
  • June 20, 2022

Semaglutide "Wegovy definitely works if you can tolerate being nauseated all the time; it takes away cravings for everything. I had to force myself to eat. Fast forward 4 weeks on meds, I ended up getting the sickest I have ever been in my life! Thought I had the stomach flu for 4 days, but it just kept getting worse. Ended up in the ER with an inflamed liver, kidneys, severe kidney infection, urinary tract infection, and dehydrated. I would do anything to lose weight because I need a knee replacement and the doctor wants me to lose 30 pounds before he will operate. This scared me, BAD. I still don’t feel 100%. Anyway, who doesn’t want to lose weight, right? Well, after my experience, this is just not worth it. By the way, I have never had any issues with kidney, liver, etc. It was from this drug."

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  • Sic...
  • Taken for less than 1 month
  • June 11, 2022

Semaglutide "Doctor skipped to 1.7, and I’ve been sick going on 4 days now. Severe nausea and vomiting, stomach pain, and headache, dehydration."

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  • Elz...
  • Taken for 1 to 6 months
  • May 29, 2022

Semaglutide "Started this 2 months ago. Was supposed to start month 3, and now they are out of stock. I have wasted money for nothing, and who knows when it will be available. From what I have read, won’t be anytime soon. Not impressed."

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  • Sha...
  • Taken for 1 to 6 months
  • April 26, 2022

"Took this for 4 weeks, all I got was a migraine I couldn’t get rid of and nausea. No weight loss, complete waste of money."

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  • Mar...
  • Taken for 1 to 6 months
  • April 2, 2022

Semaglutide "No weight loss at all in 3 months. I’m at 1.5 dose now. I also have a sluggish thyroid, so not sure. Feel an upset stomach, acid reflux, and nausea. And very tired after the injection. Have lost about 3 lbs and gain it back by the next day. I eat low carb, and usually I’m not hungry. I have no idea why I'm not losing any weight."

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  • Jax...
  • Taken for 1 to 6 months
  • March 31, 2022

Semaglutide "I had to stop Wegovy after my 9th week. I have autoimmune issues, and 2 days after I increased to the 1.0 dose, my right side was hurting so much. I went to the doc and had an ultrasound. My gallbladder is inflamed. I now need surgery, and also my inflammation C Reactive Protein count is normally at .5, it was 12 yesterday. It is supposed to stay under .5. Beware if you have any autoimmune issues, because when I went up in dose, it made my immune system go crazy. I’m praying this drug leaves my system quickly. Took it 3 months and only lost 2 pounds. Never again."

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  • Mic...
  • March 6, 2022

Semaglutide "I started my first dose 1 day ago. I have been vomiting ever since. I can’t keep anything down. This is HORRIBLE…"

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  • Mer...
  • Taken for 1 to 6 months
  • February 25, 2022

Semaglutide "I am on 1.0 and am always sick. I have lost 22 pounds since 11/2. I haven’t lost in 3 weeks. I can’t live like this. I am not taking another injection."

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  • Mik...
  • Taken for 1 to 6 months
  • February 22, 2022

Semaglutide "6 weeks have lost nothing. No side effects, no nothing."

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  • tad...
  • Taken for less than 1 month
  • January 27, 2022

Semaglutide "Just started my 4th injection (1 month) and nothing. Barely noticeable side effects, but disappointed that it is not working, considering the cost. I am hoping it starts working with higher dosages (if I can afford it)."

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  • Anonymous
  • Taken for less than 1 month
  • January 22, 2022

Semaglutide "Worst experience of my life. After the second 0.25 dose, I was up all night vomiting and diarrhea. The next day, I had chest pain, shaking, brain fog, stomach pain, more diarrhea, and had to go to the ER. After they gave me Benadryl and morphine, I started to feel better. Still have burping, gas, and acid reflux terribly. WILL NEVER TRY THIS AGAIN! It is not worth it to me! Wish it would hurry up and get out of my system."

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  • fin...
  • Taken for 1 to 6 months
  • January 17, 2022

Semaglutide "Took it for 8 weeks, made it through the 2nd titrated dose and couldn't handle it anymore. Nausea, gas, bloat, constipation, diarrhea, and it was worse at night while lying down. Never improved, but actually got worse by week 8. Not sure how anyone makes it to the full dose. Also did not drop a single pound. There were days I only consumed 600 calories and still felt awful. I read another review very similar and agree that you absolutely cannot eat anything spicy. Bland food days were better but there are not enough antacids and constipation meds in the world to make me want to lose 20 pounds this badly. Took my last dose 10 days ago and am still dealing with residual GI upset. Hope physicians are more forthcoming about the side effects and do not tell patients they happen but subside in a couple of days - they do not."

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  • Kma...
  • Taken for 1 to 6 months
  • January 10, 2022

Semaglutide "First of all, this does work. I lost over ten pounds in 6 weeks. The weight just fell off. Second of all, this was the worst experience I have ever had with a prescribed medication. Well, I started at the lowest dose and took that for 4 weeks before moving to the next dose, which I believe was 0.5 mg. The maintenance dose is 2.4 mg, I believe. How anyone makes it to the 2.4 mg is beyond me. I made it to the second dose of 0.5 mg before I threw in the towel. This stuff is WICKED. I spent 6 weeks of my life with an upset stomach, the absolute worst reflux and heartburn I have ever had, and constant nausea. I had to literally force myself to eat. Would not recommend. The side effects and the price are not worth it. Easy to lose weight when you are starving yourself and feel too sick to eat. Once I stopped, it took a few days to feel better and the weight came back lightening quick plus a few. Not worth the misery in my opinion."

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  • AMa...
  • January 2, 2022

Semaglutide "I’m on Week 15 of treatment and have lost nothing. On the first dose of 0.75 mg, I experienced heartburn, fullness, and zero appetite for 5 days. I was hopeful that it had finally started to work. On subsequent doses of 0.75 mg and 1 mg, and now on 1.7 mg, I’ve felt no effects from Wegovy. I’ve tried switching injection sites from my abdomen to my arm with no effect."

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  • And...
  • Taken for 1 to 6 months
  • December 5, 2021

Semaglutide "Does not work for me. I am on 1 mg. Been on it a total of 2 months and 1 week and lost 5 pounds. Does not curb my appetite."

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  • Jan...
  • Taken for less than 1 month
  • December 2, 2021

"I only did two of the .25 injections. They didn’t do much to suppress my appetite, so I was looking forward to using the increased doses. However, both times, two days after each injection, I got swelling, redness, and a rash around the injection site. A week later, the reactions have barely improved. One was in my thigh, and one in my stomach. I discontinued use."

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.