Seroquel and Drowsiness: What Users Say (Page 5)

• lyn...
• Taken for 10 years or more
• April 3, 2025

For Bipolar Disorder "This drug literally saved my life. At first, it is hard to get used to the fogginess and feeling sleepy, but most of the side effects went away after 6 months. I did gain about 30 lbs, but that was over the course of 10 years and I have recently been able to get it off. I have had to keep track of calories and eat well to not gain weight on this med. However, that is a better lifestyle anyway. This med helped so much with my OCD/intrusive thoughts and depression. I don't know if I will ever go off this med. At this time, 50-100 mg is all I need. However, when I have a major depression episode, it is increased to 200-300, but that has only happened 2x in 18 years. I felt I needed to write this for someone on the fence about trying this medicine or not. I am glad I did."

• Jul...
• Taken for 6 months to 1 year
• September 20, 2024

"My psychiatrist suspects I have cyclothymia, as my mood can shift at the drop of a dime, and I absolutely do not respond in any meaningful way whatsoever to typical antidepressants like SSRIs, SNRIs, etc. I felt hopeless after searching for ~7 years for something that worked. I typically react horribly to antipsychotics, experiencing a severe dystonic effect. However, I haven't gotten that with Seroquel. And, lo and behold, it actually works for my depression. No, it hasn't 'fixed' or 'cured' it, but no one should expect a cure. I actually have the motivation to do things and no longer am held back by constant suicidality and depressive moods. It really helped pave the way to getting my life back. The only side effect, which can double as a benefit to some, I've gotten is sleepiness. Just take it at night/before bed and that's hardly an issue. I take 200 mg daily, but it may functionally be closer to 250 mg due to another medication (Luvox) I take."

• xfr...
• Taken for less than 1 month
• February 18, 2022

"Was given Seroquel 25 mg for anxiety, and it completely knocked me out, totally unconscious. I could not function at all. Day 3 on the Seroquel, I was so unconscious that I wet the bed and didn't even know until the next morning. I have injuries and bruising that I have no explanation for. Also raised my resting heart rate from 64 to around 100. Quit after one week. Googled it, and there are lawsuits against this med. Please research it."

• rab...
• Taken for less than 1 month
• January 22, 2025

For Bipolar Disorder "Far and away, the worst medication I have ever taken. It made me feel like a walking zombie, constantly agitated and hungry. It did induce significant drowsiness, but in the worst way."

• Sco...
• Taken for 1 to 2 years
• October 1, 2014

For Bipolar Disorder "This medicine turned me into a zombified eating machine. I put on 30 pounds in one month. It was also extremely sedating."

• Anonymous
• Taken for 1 to 6 months
• November 7, 2019

For Schizophrenia "Seroquel makes the psychosis easier to deal with but makes me very tired. Experienced side effect drowsiness every time I took it."

• Anonymous
• February 23, 2011

For Generalized Anxiety Disorder "Withdrawal is nasty in spite of doctors saying there are no withdrawal effects. It is sedative and can be impairing, so drivers, be careful."

• Anonymous
• March 10, 2008

For Bipolar Disorder "It took me down from a manic episode relatively quickly, but after the mania stopped, I just felt sedated all the time. I don't love Seroquel, but it has its benefits."

• Sar...
• February 27, 2009

For Borderline Personality Disorder "Made me a zombie. I could sleep for 24 hours after one pill. I have things to do, I can't sleep that long."

• Anonymous
• May 29, 2008

For Bipolar Disorder "It worked very well, but it caused excessive drowsiness and also made me gain a lot of weight in a short period of time. I took it for almost a year before I switched to something else."

• Bip...
• Taken for 6 months to 1 year
• February 21, 2016

For Schizoaffective Disorder "Works kind of well, but you will sleep like nonstop, and you will gain weight. I gained at least 30 pounds on this med and was sleeping like 14 hours a day."

• Sch...
• December 16, 2008

For Schizophrenia "It worked really well for a little while, but I've started having delusions again. It still helps, though. It also puts you to sleep."

• Anonymous
• June 30, 2011

For Insomnia "Causes too much daytime drowsiness. Works well as a sleep aid, but there is too much carry-over sleepiness during the day."

• Anonymous
• August 19, 2008

For Bipolar Disorder "I have been on 400 mg of Seroquel for 6 months. It helped me sleep and also took away my voices that I was hearing. It works great, but I feel drowsy."

• Els...
• Taken for 2 to 5 years
• May 25, 2018

For Bipolar Disorder "I give Seroquel 7 out of 10. It works like a charm for my crazy head, but that doesn't seem to change the fact that it has sedative side effects."

• Doe...
• Taken for 6 months to 1 year
• February 25, 2016

For Bipolar Disorder "I spent months on this medication, and all it ever did for me was make me drowsy. All I ever did was sleep, not worth the toxicity to your liver."

• Out...
• September 22, 2009

For Bipolar Disorder "Expensive if you buy the extended release ($160 for 50 mg twice daily a month). Not to mention very sedating and weight gain."