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Prometrium and Headaches: What Users Say

Headaches: mentioned by 4 users (10.8%)

Based on user experiences from 37 Prometrium reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

sore breasts 21.6%
tiredness 21.6%
vivid dreams 13.5%
weight gain 13.5%
dizziness 10.8%
headaches 10.8%
irritability 8.1%
mood swings 8.1%
shortness of breath 8.1%

Reviews for Prometrium

Showing 4 reviews tagged with "headaches". Clear filters to view all 37 reviews.
Commonly mentioned side effects
  • Anonymous
  • Taken for less than 1 month
  • October 23, 2020

For Uterine Bleeding "I am on 200 mg Prometrium due to uterus bleeding and enlarged uterus wall. Other than the bleeding, I had no post-menopause issues (I am 57 with high estrogen levels). After 2 days of taking the medication, bleeding stopped - great! After a few more days, I started gaining weight, breast tenderness, breast enlarging, very strange dreams every night, very tired during the day although I sleep at least 8 hours now, and bad headaches. Too many side effects for me. I went to my naturopathic doctor to do detailed hormone tests. Result = extremely high progesterone level. Make sure you get your hormones tested before taking the medication!"

3 / 10
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59 Report
  • SL2...
  • Taken for less than 1 month
  • June 12, 2022

For Perimenopausal Symptoms "I tried taking 100 mg of Prometrium daily for 3 days after entering menopause at age 51. I have not had a period in almost 1 year. It is awful stuff. It immediately gave me a horrible dull headache, a sense of depression, and a feeling of malaise. I'll stick with natural remedies for hot flashes, which Prometrium also made worse, frankly. It is also worth noting that I have never taken birth control or any other hormone supplements."

1 / 10
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41 Report
  • swh...
  • Taken for less than 1 month
  • October 23, 2012

For Progesterone Insufficiency "I am 49 and have been on this medication for one cycle. The side effects have not been as bad as I had anticipated. I had a few mild headaches, a bit of bloating, tender breasts, and a mild acne breakout, and was a bit tired a few days. I am taking it for a proliferative endometrium, and after 4 days being off the medicine, I am getting a period, so it seems to be working as planned. I am taking 200 mg."

8 / 10
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50 Report

Frequently asked questions

  • She...
  • Taken for 1 to 6 months
  • December 12, 2016

For Premature Labor "Mild side effects such as fatigue and hunger, horrible headaches if not taken at all. Seems to work, however, for the price paid for the medication, seems like they could include an applicator like the ones they give with gels and OTC yeast meds, etc. It's not fun or very easy trying to shove pills in your VAGAY with your fingers every single time you must use this medication."

6 / 10
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13 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.