Prometrium and Mood Swings: What Users Say

• Anonymous
• Taken for less than 1 month
• July 13, 2019

"I am 21 years old and in about 2 months gained 30 pounds although I worked out consistently and kept a clean diet. In addition, I wasn’t sleeping, was retaining so much water I could not wear rings, and had horrific mood swings. However, my main problem was that I could no longer breathe, just speaking or walking felt like a marathon. For 8 months, I have had an endless nightmare of appointments and tests with different medical specialists with no answers. After loss of all hope, I finally decided to see a hormone specialist. Because of a mild progesterone deficiency, she recommended Prometrium for 6 weeks. I have been on 200 mg of Prometrium for two weeks now and after only 3 days, I started noticing my water retention lessening and I could breathe again! I can now work out better than I ever have been able to in my life, I sleep well, my stress levels are down, and my mood swings have subsided. This medication may have saved my life. Get your hormones checked!"

• Jac...
• Taken for 1 to 6 months
• May 8, 2022

For Progesterone Insufficiency "Side effects not worth the gain. Had been using bioidentical progesterone (via a troche) for the last 12 years with no side effects, until my doctor retired, leaving a 5-month wait for a new bio-id doctor willing to take on new patients. In the interim, I moved to an online service that prescribed Prometrium. It's awful. I wake each morning feeling like I've been hit by a bus: deeply tired, no energy, no libido, and a consistently flat mood bordering on mild depression with swings of moodiness. The worst symptom, though, is the extreme increase in asthma and struggle to breathe even after the lightest exertion (something I've not experienced before and is equally frightening for my family). The service advised me to double the estrogel, hoping to balance it, then to cut the Prometrium dosage in half, but that's causing noticeable weight gain and the side effects lessen on the day after I don't take it, but not significantly. It's been 3 months of struggle. This drug clearly doesn't suit me."

• Anonymous
• October 19, 2011

For Progesterone Insufficiency "I am on a 100 mg dose, days 14-28 of my period or the first 12 weeks of pregnancy. The first month was great, I felt level. The only side effects felt were extreme sugar cravings and vivid, bizarre dreams. However, in month two, no cravings, extreme mood swings, and ranging from a need for a lot of sleep, not wanting to get out of bed, to anxiety and very little sleep. No pregnancy yet."