Prochlorperazine and Restlessness: What Users Say (Page 3)

• Owe...
• Taken for less than 1 month
• March 12, 2022

Prochlorperazine for Nausea/Vomiting "Compazine, as listed by a lot of people, is an awful drug. I went into the ER with a headache and nausea and was given Benadryl and Compazine via IV in order to quell it. Immediately after the IV went in, I started to feel very anxious and have dark thoughts. All I wanted to do was jump out of the hospital bed and run out. Once I was discharged from the hospital, the side effects did not go away. I felt like I just wanted to be knocked out to help stop this feeling. I cannot even believe I was able to get sleep that night, but thankfully I did. Even though I got sleep, however, it is the next day, and I still feel restless and jittery. It is a lot better now, but I do not know how much longer it will last. DO NOT TAKE COMPAZINE!!!!"

• Nat...
• Taken for less than 1 month
• June 24, 2022

For Nausea/Vomiting "I got prochlorperazine in my IV as part of a migraine cocktail at the ER. I didn't understand why I was getting really anxious while waiting for the IV to finish up. I was driven home, and after a half-hour or so, there I was in full-blown akathisia. The mental anguish was harder to bear than the physical pain I'd had from kidney stones. (That's all I can think of to compare it to.) I drove myself back to the ER, the whole way talking myself out of finding a cliff to drive off of to end my suffering. Back at the ER, the MD diagnosed my akathisia and told me diphenhydramine ought to ameliorate my symptoms. He seemed to have been right. I can't imagine any future condition under which I would consent to receiving prochlorperazine again."

• Els...
• Taken for less than 1 month
• March 18, 2019

"I was given Compazine IV to treat a migraine. This made me feel more lousy than the migraine itself. I couldn't get comfortable, I was restless, I was pacing and anxious. My heart was racing, and I was trembling uncontrollably. I didn't know whether I wanted to lay down, stand up, or sit up. It is 24 hours later, and I still feel the same way. I am an RN, and I have witnessed others experiencing the same adverse reactions to this medication. I would not recommend this drug to anyone for any reason. The slight benefits do NOT outweigh the risks."

• mai...
• March 3, 2022

For Nausea/Vomiting "I went to the ER for a migraine, and they gave me this for nausea. Worst experience of my life! I immediately started feeling panicked and restless, and my heart rate shot up to 130 even though I was lying down. I ripped out my IV, got up, and paced around, convinced that I would feel like that forever. The nurse came in and told me it was normal and just wrapped me tight in warm blankets so I couldn't move. I couldn't stop shaking and crying until it went away a couple of hours later. Even the Benadryl they gave me as an antidote didn't work. I was wrong in thinking this was a rare side effect! Stay away if you can!"

• Cj1...
• December 27, 2015

Prochlorperazine for Nausea/Vomiting "Extreme agitation and anxiety... Never again... Very restless."

• Rid...
• Taken for less than 1 month
• January 2, 2021

For Psychosis "Restless, can't sleep, feeling not being myself. Focus disturbance. Feeling really."