Skip to main content

Pemoline User Reviews & Ratings

Pemoline has an average rating of 9.8 out of 10 from a total of 19 reviews on Drugs.com. 100% of reviewers reported a positive experience, while 0% reported a negative experience.

Condition Avg. Rating Reviews Compare
ADHD  
9.8
19 reviews for ADHD 43 medications
Add your review

Reviews for Pemoline

  • Mark
  • Taken for 10 years or more
  • January 28, 2019

Cylert (pemoline) for ADHD "Started taking it in 1987. It changed my life immediately for the better. Things are not the same since it was taken off the market in 2005. I have tried them all and nothing has worked for me. I wish Abbott Labs could mimic the compound without the side effects."

10 / 10
Was this helpful?YesNo
  • rocem...
  • July 6, 2017

Cylert (pemoline) for ADHD "No better ADHD drug on the planet and I have tried them all. I started with cylert and Wellbutrin in 1997. My life changed, I cannot even describe how much. I became the person I always knew I could be. 2005 the cure was taken off the market. After so many different drug attempts and extended periods without any medication. I'm now on Vyvanse. Let me tell you it does not hold a candle to cylert but I thought I was somewhat closer. I have done my research and the "cure" still exists. I was so happy to ready the above comments. I feel a little less alone."

10 / 10
Was this helpful?YesNo
  • Satur...
  • January 29, 2015

Cylert (pemoline) for ADHD "I took this medicine from the mid 70's until it was banned in the US in 2005. There is no other medicine like it that I have found. A very small dose each day kept me focused and improved my memory and mood. It never affected my appetite nor kept me awake at night and there was none of the emotional roller-coaster effect I find with every other medicine I have tried since."

10 / 10
Was this helpful?YesNo
  • ADHD...
  • May 5, 2015

Cylert (pemoline) for ADHD "Wish it was still available. I miss being able to function like a 'normal' adult. Dexedrine, Ritalin, Adderall, Concerta, Strattera, Wellbutrin - none of these worked. some lessened appetite, some turned me into a zombie. Cylert worked - yes some side effects, mainly tourettes-like, but in order to function normally? I'll gladly cluck like a chicken randomly to concentrate (that was my side effect). Life without is back to my reality - oh, look, a doorknob. I wonder how it works? I bet it's some sort of cam mechanism that operates via - oh, look, a wireless transceiver, I wonder if it is in the 2.4 Ghz spectrum or if it is - oh look, a wireless mouse, I wonder if it operates via bluetooth or is on the same 2.4 Ghz spectrum as the - oh look......."

10 / 10
Was this helpful?YesNo
  • Freak...
  • October 1, 2008

Cylert (pemoline) for ADHD "I took this for about a year, about 10 years ago, and I still think it was one of the best ADHD drugs I ever took. I remember many of my nervous behaviors were significantly decreased. For once, I had enough fingernails to actually need a nail clipper! I actually had less trouble falling asleep at night, and don't recall any problems with appetite. I did have some moodiness, but I'm not sure whether it was the drug, or pre-existing depression. Another plus is it's not schedule II, so you don't have to try and remember to get your prescription every single month. "

9 / 10
Was this helpful?YesNo

Are you taking this medicine?

  • Overt...
  • September 14, 2018

For ADHD "My Dr. Started prescribing me this medication in the early 90s. It was the perfect medication for me. I was able to focus. Get me from getting tired. And I was able to sleep at night. When the drug was discontinued. My new doctor tried me on Ritalin, Adderall, Wellbutrin Etc. None of them have seem to work as well. Although my Dr did keep me on Ritalin. Until I had heart surgery. Cylert, although it has alleged liver side effects. Does not seem to have cardiovascular issues the same as Ritalin or Adderall. I was fortunate to find an expired prescription for pemoline in my medicine cabinet. Which I have taken the last 2 days. Although the prescription is expired by almost 10 years it has not lost any of his effectiveness. And at least for the last few days I have felt great. I wish the drug would come back!"

10 / 10
Was this helpful?YesNo
  • Wjam
  • Taken for 2 to 5 years
  • May 19, 2013

Cylert (pemoline) for ADHD "I started on Cylert in 1990 and my brain activity took off. I was concentrating better, I wasn't as nervous as I used to be. I stopped taking it because my doctor moved from one location to out of state. I figured I'd give it a try without it. I went back on it in 1998 for a period of time and felt as I did back in the early 1990s. I now cannot get it because of hepatic problems, but I am willing to keep taking it because it is and was the best ADD medication I have ever had. I am very upset and sorry for all of us who do not use it anymore and there are no more alternatives closest to Cylert. Maybe one day there will be, but until then, with all of the medications I have tried, my mind will continue to spin and constantly be on run."

10 / 10
Was this helpful?YesNo
  • Jandji
  • Taken for 10 years or more
  • January 24, 2021

Cylert (pemoline) for ADHD "I loved Cylert! It saved my life in my opinion, it made me come to life and wake up. When it was taken off the market my world changed upside down and I have struggled with my health ever since. Best medicine ever"

10 / 10
Was this helpful?YesNo
  • 5yrol...
  • September 13, 2010

Cylert (pemoline) for ADHD "Doctors would often laugh when they heard which medication I was taking for ADHD: Cylert, I was on a "kid dosage": 37.5 mg, 1 in the morning. I was diagnosed with Attention Deficit as a young adult. I'd struggled my whole life with social anxiety, depression, impulsiveness, inability to remain in stable relationships. Maintained a good GPA through my Junior year in University and couldn't tolerate one more year. I'd always been creative and quickly learned what interested me. I was shocked when Cylert was blackboxed. My liver function was fine and I had a normal sex drive. After decades of demanding high-tech jobs, one day Cylert just quit working. Ritalin..finally Adderall. Both killed my sex drive. BUT I could focus! Switching to Dexedrine ER."

8 / 10
Was this helpful?YesNo
  • Tradon
  • June 5, 2018

For ADHD "Like some people above said it is too bad, that pemoline is not available anymore. The mechanism of action is unique! Pemoline changed my life. It was not a drugged up feeling, but a feeling with slight euphoria and a very good focus for about seven hours. There was no crash and bad comedown like with amphetamines and Ritalin. In Germany the drug was taken away in 2006. I had a prescription in my hand and the women in the pharmacy told me, that it is not sold anymore. Can you imagine how I felt? It was horrible... We are writing the year 2018 and it is twelve years after they removed it from the german market but I canĀ“t forget and I will not forget!! I invested hundreds of hours with research and here are the things I found out. The good news is, it is not cancelled in every country. There is one country where it is been prescribed. It is Japan! So if you have a doctor who will give you a prescription, I think there is a chance to obtain it from an international Pharmacy"

10 / 10
Was this helpful?YesNo
  • Anonymous
  • Taken for 10 years or more
  • July 20, 2022

Cylert (pemoline) for ADHD "I took Cylert since the 80's. It was the absolute BEST medicine on the market for ADHD. This medicine kept me in check with my attitude, drive, focus ability and provided me a huge amount of thinking creativity. I had excelled in my job and was on top. Until 2005 when my world crashed. I have tried everything on the market and NOTHING compares to Cylert. I struggle each day and wish we could turn back the date. Abbott Labs, there are a huge number of us who want there lives back. Please consider creating a similar compound to Cylert. Keep the faith everyone. The struggle is real and I'm there with you."

10 / 10
Was this helpful?YesNo
  • JS106
  • Taken for 10 years or more
  • August 31, 2022

Cylert (pemoline) for ADHD "I took this med for 14 years at low dose (37.5 mg) and (with it) completely turned my life around. I became focused, my creativity ceased being chaotic. I experienced no negative side-effects. During a period of *extreme* personal/work stress and trauma, the drug quit working. Psych Doc tried doubling the Cylert dose: this made me incredibly anxious, which was confusing and frightening. Ritalin next, which worked for a few months, then didn't. Next, Adderall (I took lowest dose possible) - both did strange things to me, emotionally. Finally Rxed low dose Dexedrine - worked much better than Ritalin or Adderall. Still, no drug has been as effective as Cylert was. Why it quit working? What I refused to do at time was give my brain and body a break. Even a great drug can only do so much."

10 / 10
Was this helpful?YesNo
  • Anony...
  • Taken for 6 months to 1 year
  • February 6, 2021

Cylert (pemoline) for ADHD "Well as helpful as it was at least this company, did the moral thing and discontinued it due to unhealthy components of it. I don't see that happening today. Medication today comes with too many side effects. Hopefully we can get the good ol days back, but doubtful."

10 / 10
Was this helpful?YesNo
  • LooLo...
  • Taken for 1 to 6 months
  • January 7, 2022

For ADHD "I was prescribed this when I was younger it was absolutely tremendous how quickly my ADHD symptoms went away and I was able to focus on what I needed to, unfortunately the FDA yanked approval away and I was switched from ADHD med to ADHD med none of which worked. And in the US I have found no equivalent to Pemoline aka Cylert and due to this my ADHD is always in full swing. I just wish they would bring it back here because none of the current FDA approved meds work they literally do nothing for me and one actually caused me health issues Cylert was the ONLY one that gave me normalcy."

10 / 10
Was this helpful?YesNo
  • Wesley
  • Taken for 2 to 5 years
  • December 27, 2021

For ADHD "Pemoline was by far the best med, a miracle for me I am ADHD, dyslexic and this drug improve them both. No replacement drug ever worked as well as Pemoline it gave me the confidence I needed to function as a speaker and to put words and sentences together."

10 / 10
Was this helpful?YesNo
  • Jenni...
  • Taken for 5 to 10 years
  • March 28, 2018

For ADHD "This drug was so amazing and it transformed my life. I was devastated when it was taken off the market."

10 / 10
Was this helpful?YesNo
  • Green...
  • Taken for 1 to 2 years
  • October 31, 2013

Cylert (pemoline) for ADHD "This was my best ADHD med by far. My doctor quit prescribing it when the liver problems emerged years ago. I didn't know it was still available. Hmmm."

10 / 10
Was this helpful?YesNo
  • Wesley
  • Taken for 2 to 5 years
  • July 4, 2022

Cylert (pemoline) for ADHD "For me it was a game changer and no other med worked like Cylert. My ability to function and become creative was remarkable."

10 / 10
Was this helpful?YesNo
  • jamie...
  • December 7, 2014

Cylert (pemoline) for ADHD "Its noz good as adderoll"

Was this helpful?YesNo

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.