Palbociclib and Joint Pain: What Users Say

• Anonymous
• Taken for 1 to 2 years
• August 1, 2017

Palbociclib for Breast Cancer, Metastatic "Diagnosed with MBC in February 2014! In breast and sacrum. Started Femara only, no progression till October 2015! Spread to two ribs and spine. Started Ibrance with Femara and scans got better and better until 2 months ago, scan showed no hot spots!! As far as I'm concerned, in remission!!! Side effects: hair loss, no taste, tired all the time, severe hot flashes, shortness of breath, joint pain, but I can live with it all!! Thank you Pfizer and everyone involved in the studies who lived and died so I may live longer!"

• TCH...
• Taken for 1 to 2 years
• June 7, 2024

Palbociclib for Breast Cancer, Metastatic "Ibrance with Anastrozole has been very effective for me. I have had a lot of fatigue interfering with my ability to work and in keeping up with daily activities at home. I also have had severe joint pain-torn meniscus bilateral knees and torn tendon in my ankle, all requiring surgery. I have no current history of arthritis or damage to joints to get the cause of this joint damage. Also, constant low back pain (some arthritis noted in the low back). However, I was diagnosed with metastatic breast cancer with mets to the liver. After 3 months of treatment, all tumors in the breast and liver decreased in size and completely gone in 6 months! Currently, no sign of metastatic disease noted per PET scan after 2 years of treatment."

• Can...
• Taken for 1 to 6 months
• December 9, 2020

Palbociclib for Breast Cancer, Metastatic "Was on Ibrance and Letrozole for 3 months, possibly the worst of my life. Could not complete 1 single cycle (started 3 in total). White cells nosedived after 15 days. Side effects included mouth ulcers, diarrhea, skin peeling on my fingers and feet soles, extreme fatigue, joint pains. After 3 months, recurrence in axillary lymph nodes + bone lesions. Going back now to chemo. Almost happy about that since it means the end of Ibrance."

• Fis...
• Taken for less than 1 month
• April 27, 2023

For Breast Cancer, Metastatic "After two weeks on this medication, I have had limited side effects besides fatigue. Some days are better than others, but about once or twice a week I sleep from 16 to 24 hours instead of my regular 12. I had joint pain and headaches in the first few days, but they seem to have subsided after the first week. A rash I get on my face over a scar has flared up directly after starting this medication."