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Opana User Reviews & Ratings (Page 2)

Opana has an average rating of 7.8 out of 10 from a total of 84 reviews on Drugs.com. 75% of reviewers reported a positive experience, while 11% reported a negative experience.

Reviews for Opana

Commonly mentioned side effects
  • pyl...
  • August 25, 2009

For Pain "Love it! Nothing better, works wonders for chronic migraines and arthritis, plus it gets me back on my feet as if I were a teen again. Gives me the little boost needed to get me through my day with limited side effects. I would recommend doctors prescribe this medicine over any other narcotic painkillers. This pill has really saved my life. It's truly amazing."

10 / 10
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  • And...
  • Taken for less than 1 month
  • July 25, 2015

For Pain "I am a chronic pain patient and have tried dozens of medications for my pain. Opana works wonders through an IV when I'm in excruciating pain, but the oral pills just don't help as much. My pain doctor switched me from Oxycodone 4 times a day to Opana 3 times a day, and it didn't touch my pain. I did some research, and it only absorbs 10% orally. It's good as an IV or injection medication, but not as much as an oral pill."

5 / 10
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  • car...
  • August 30, 2009

For Pain "I have been on Opana 20 mg ER for almost a year now. I changed to Opana as my insurance would no longer cover the OxyContin. It took my doctor almost 6 months to figure out a dose that was acceptable to me. Aside from occasional head sweats, I like the Opana a lot. Every once in a while, I experience night terrors, but do not know if they are related to the Opana or not. As far as my pain is concerned, they seem to do the job well, and I do not get the side effects that I got with the OxyContin."

8 / 10
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Frequently asked questions

  • Bea...
  • Taken for less than 1 month
  • May 14, 2016

For Pain "3 back surgeries, 35 days since the latest fusion in the lower back. Been on pain meds for years, mainly Percocet 10 mg, which seemed to be the only thing that helped. Even when given stronger meds. I guess my body is so used to them now they stopped really working unless I took 2 at a time. My surgeon suggested Opana for me this past week, it's been only 4 days, but it doesn't seem to work at all. It does nothing for the pain. I have the 10 mg IR. I'm a very active 45-year-old who loves to fly fish, camp, hike, play basketball, play softball, and go on long hikes with my dogs, but I can't do anything anymore. The latest surgery they had to go through my stomach, and I just want some relief so I can start being active again... miserable."

2 / 10
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  • jvw...
  • November 2, 2010

For Pain "I have found Opana ER to be a lifesaver for me in that though the pain is not gone, at least it is tolerable. What works for me presently is a 30 mg dose 3x a day along with Neurontin. Taking the Opana 3x a day takes care of it possibly wearing off earlier than it should by giving me the medicinal coverage and avoiding the need for breakthrough medications. I initially was taking 40 mg 2x a day with the Neurontin, and between my doctor, pharmacist, and me, this protocol works much better, and Medicare will cover it. It was a long, difficult journey to get to this point of reasonable comfort, which is governed by activity levels and the weather. I do not cry so much anymore from the pain levels I have from a myriad of medical disabilities."

9 / 10
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  • Liv...
  • July 12, 2011

For Pain "Been on Opana now for roughly 1.5 years. Stool movement is difficult, and most of the time you feel bloated. With that being said, pain is not a problem with the current medication. 2x 20mg ER (morning, night) with 4 x 10mg IR for breakthrough pain. I have L5 S1 area problems. Sweats are also difficult at times in the heat."

8 / 10
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  • Guy...
  • January 20, 2011

For Pain "Good long-term analgesia with the extended-release formula, which seems to work for over 8 hours, though I don't think it has the full 12-hour benefit as advertised. Less 'fuzziness' than oxycodone (or even hydrocodone), which is a positive for me. I suppose it's not so good for 'recreational' users - the new ER formula is supposed to be highly abuse-proof - but for those in REAL chronic pain, Opana-ER works well, similar to OxyContin, and is very easy to use - one dose in the morning, another in the evening."

7 / 10
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  • Got...
  • May 18, 2010

For Pain "Have been taking 40 mg Opana 2 x's/day for about 10 months now for a compressed disc/pinched nerve in my neck, chronic migraines, and fibromyalgia. Opana SAVED MY LIFE! I was on 8 x 10 mg Norco daily, which was NOT working. We began Opana, and I was able to gradually function almost normally again as a busy photographer and mother of 5! HOWEVER, lately, I have noticed increased breakthrough pain EVERY DAY, but am scared to ask my doctor about increasing my dosage for fear he'll REDUCE my dosage, and thoughts of me curled up in bed in pain again terrify me! Does anyone have any thoughts on this dosage? I KNOW it would help me regain my normal activities that have decreased. I want my LIFE back, and Opana has TRULY enabled me to function productively up until now."

8 / 10
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  • EDS...
  • Taken for 1 to 6 months
  • July 5, 2016

For Pain "I was switched to Opana from OxyContin because even 150 mg of Oxy a day wasn't managing my pain anymore. Opana was said to work just as effectively at lower doses, with fewer of the miserable side effects of Oxy (constipation, drowsiness, etc.). I have found that to be the case in general; my daily dosage is more like 50-80 mg per day on this med, and I can go to the bathroom again without using a suppository first. My pain control started out slightly better on this med, but since I'm a fast metabolizer of opiates, I've started developing a tolerance to this one too, and the pain is bothering me again to the point where I can't function. My major complaints about this med are that it is very hard to find, and it is costly."

7 / 10
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  • Anonymous
  • January 15, 2011

For Pain "I have to say, the IRs work much better than the ERs for me. I take 6 - 10 mgs per day. I used to be on many other things for pain, such as OC 80s and MS 100s, but the roller coaster leveled right out as soon as I started the Opana, and the pain leveled also. Everyone is different, and everyone's pain is different, so suggesting a certain pill is hard for me to do. Hope if you are given these, best of luck with your pain, as they worked for me."

10 / 10
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  • MBR...
  • Taken for 1 to 6 months
  • March 14, 2016

For Pain "Changed my life! I was on Norco for 10+ years, and it stopped working. I started the generic Opana, and it makes my pain tolerable. I'm not sure, but I am retaining a lot of fluid. This is the only thing I am concerned about."

9 / 10
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  • Anonymous
  • November 25, 2011

For Pain "I have injured my back several times over the course of about 12 years. I have tried everything under the sun. I am currently on the 5 mg ER 2 x daily and the 10 mg IR 3-4 x a day for breakthrough pain. Like many people have said, you have to take it on an empty stomach. This medicine works better than any other. As long as you take 2 x ER and 3-4 IRs for breakthrough per day, you will have the best results. I am due for my ERs to get increased, but other than that, this is the best pain management I have ever had."

10 / 10
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  • Nob...
  • July 1, 2014

For Pain "I have been on Opana IR for 4 months now. I have severe migraines due to a cyst on my brain, along with 2 bulging discs in my neck. It works okay, but I also have Stadol nasal spray if the Opana doesn't help. I'm on 5 mg 2x a day. I honestly need stronger, but since it's migraines, he won't increase it. I would recommend it for small pain."

6 / 10
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  • Ale...
  • January 14, 2016

For Pain "I have been on Opana ER 15 mg for 3 years now. Was diagnosed with a herniated disc with an annular fissure at L3, 4, and 5. Also have degenerative disc disorder, spinal stenosis, plus more back problems and diagnosed with fibromyalgia. All I can say is the Opana ER crush-resistant are junk. I was prescribed Oxymorphone Hydrochloride ER 15 mg, a green pill. The pill form was a miracle for me, I could get up and go to work 12-16 hours, and they last with hardly taking a Percocet for breakthrough pain. Had my life back with the generic. The name brand Opana ER is junk. I always have an empty stomach when I take it, and not even an hour later my stomach is upset and I always have diarrhea."

1 / 10
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  • Luc...
  • July 7, 2016

For Pain "I started Opana about 5 months ago. The withdrawals make you feel like you have the stomach bug and flu at the same time. Night sweats, every bone feels broken, stomach cramping, strange negative thoughts that aren't real. This medication didn't help at all with my disc herniation, gout, broken foot, sore tooth. First night, I wondered if I would make it through the night. I was on 40 mg twice a day, 12-hour ER. I wouldn't suggest this medication to anyone. It's hard to require medication assistance just to move, but it's even worse being on a medication that didn't help and caused the worst withdrawals of my life. It took 9 days to feel better! Good luck."

1 / 10
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  • Anonymous
  • July 12, 2010

For Pain "I fell over a year ago and have had chronic back pain ever since. I have bulging discs in L3, 4, and 5, degenerating discs, and spinal stenosis. I have tried Norco, which no longer works. I recently tried Nucynta (no pain relief and very tired side effects), so I am sticking with the Opana. Overall, it does a pretty good job with pain. I just feel like my tolerance is building up over the 9 or so months I have been taking it. I take 20 ER first thing in the morning, and 10 mg IR one or two more times during the day. I still take Norco for breakthrough pain, but even that doesn't seem to touch the pain anymore... I recommend Opana for pain relief, and I can still work with a clear head!"

9 / 10
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  • mel...
  • April 5, 2009

For Pain "This medicine has been very effective, however, it doesn't last the full 12 hours of pain relief as it is prescribed. For me, it lasts about 8 hours. I did get horrible constipation, so stay hydrated. Never flush unused drugs down the toilet. It can severely affect fish and other animals along the watershed. Water treatment plants do not treat for disposed drugs."

9 / 10
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  • car...
  • September 19, 2009

For Pain "Works much better than the oxy's for my arthritis. I don't get such wicked side effects, either. The Opana winds me up, but not nearly as much as the Oxycontins. Also, the hot flashes are nowhere close to what they were."

8 / 10
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  • Anonymous
  • October 21, 2010

For Pain "I have Behcet's, Castleman's, fibromyalgia, osteoporosis, degenerative disc disease. All equals severe pain. I tried everything. I now take Opana 30 ER 4 times a day and Norco 10/325 8 times a day for breakthrough pain. Before the Opana, I wanted to die to get away from the pain. I couldn't play with my 4 kids. All they heard was, 'Not right now, Mommy hurts.' Now I have my pain under control, and I can live my life and play with my kids."

10 / 10
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  • phi...
  • August 28, 2009

For Pain "I was on 200 mcg of Fentanyl patches, and 100 mg of MS Contin 3 times a day and 30 mg of MSIR (instant-release morphine) 3 times a day for almost 7 years for these horrible migraines I have constantly. These medicines were not helping anymore after being on them for so long. About 6 months ago, I changed doctors who switched me to Opana ER. I am taking 80 mg every 12 hours along with 600 mcg Fentora 3 times a day for breakthrough pain. I have not had any side effects from the Opana at all, which is wonderful, and I can function daily and not be laid up in bed constantly. I would definitely recommend Opana ER, but just think about something for breakthrough pain in case it is needed."

8 / 10
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  • Zba...
  • February 19, 2016

For Pain "I've been on oxymorphone for 10 years. My Dr. just put me on Opana 40 mg instead. It's been 3 days and I'm going through withdrawals. I have gastropathy, which slows down your digestive system. Seems my pain Dr. doesn't care. I had the test a couple of years ago that checks to see if you're on the right medications. It showed that the oxymorphone and Roxicodone were being processed and were the right medications for me. A couple of months ago, they wanted to put me on a morphine patch. And I said no. I think that he is being paid to write Opana scripts all of a sudden, which to me is BS! I hate the gel Opana, it doesn't digest properly. My insurance prefers generic because it's cheaper. I prefer it because it took care of my pain, whereas Opana doesn't."

1 / 10
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  • bur...
  • February 27, 2008

For Pain "Been on fentanyl patches for 3+ years now. Wear 2 50 mcg patches. Recently started on Opana ER 20 mg twice a day and only wearing 1 patch changed every 48 hours. Pain level has gone up slightly, but also side effects from the patch have decreased, which to me for now is an acceptable trade-off. Breakthrough pain occurs sooner, but have not tried the higher dosage yet. Have somewhat raised expectations to come off patches by the end of the year."

8 / 10
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  • ros...
  • June 10, 2014

For Pain "Too strong for me. If taking Opana 30s for the first time, I suggest starting off with smaller doses then increasing gradually. Took one the other night, nausea set in and I vomited. Great loss of appetite, like on Adderall, minor drowsiness."

9 / 10
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  • gol...
  • January 26, 2012

For Pain "I was currently taking Exalgo 12 mg once daily and 2 mg Dilaudid twice daily. It started not to work, so my doctor put me on Opana 40 mg twice daily and kept my Dilaudid. So far, taking Opana is great, it lasts long enough to take my second dose, and I couldn't be happier."

9 / 10
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  • mic...
  • June 11, 2009

For Pain "I am permanently disabled due to brain surgery, leaving me with a condition called occipital neuralgia (headaches 24/7). Opana is a wonder drug for me. I tried every single other treatment I could find, from physical cures, psychological cures, to every other narcotic available. It is now time for me to get off of the drug because my body has finally become used to this pain enough where I hope that I do not need drugs for the rest of my life. Right now, I am taking Opana 40 mg ER X 4 = 160 mg ER and Opana 10 mg X 4 = 40 mg per day. My total Opana consumption daily is 200 mg. I just finally got up enough guts to ask my doctor to cut my dosage back, so I am going to try to cut the Opana 40 mg ER down to Opana 30 mg ER X 4 = 120 mg ER."

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.