Zofran ODT User Reviews & Ratings (Page 2)
Zofran ODT has an average rating of 7.2 out of 10 from a total of 59 reviews on Drugs.com. 67% of reviewers reported a positive experience, while 26% reported a negative experience.
Reviews for Zofran ODT
- Renee
- Taken for 10 years or more
- March 9, 2022
For Nausea/Vomiting "I have been taking Ondansetron, 4 mg ODT for years to treat severe nausea after I eat too many carbs during a meal. When I feel the nausea starting, I put 2 tablets under my tongue followed by a Chewy Tum and a Prilosec ODT. I was given Promethazine before Zofran was available to me which worked fantastic cuz it puts you to sleep and you sleep thru the nausea episode which is not practical when you are working. Zofran saved me by allowing me to recover from nausea episodes taking 30 minutes out of my day vs 1/2 or entire day off work. Great drug!!!"
- lwano
- Taken for 5 to 10 years
- March 8, 2019
For Nausea/Vomiting, Chemotherapy Induced "The brand Zofran worked perfect. Generics (Mylan, Rising, Glenmark) began coming out 2 years later. These made sicker & caused headaches. Zofran contains .03 mg aspartame. Generics have .51 mg. Naturally insurance won't cover Zofran. I'm just glad I got it when I first started chemo when sickest."
Frequently asked questions
- Dmp
- April 11, 2017
For Nausea/Vomiting "This stuff works like a dream and quickly! I take over 20 meds a month, and sometimes I just get flat out nauseated from my "cocktail from hell". I have also had it administered in an IV, and it cant be beat. The only downfall is the cost...the last I heard it is $20 per pill, and Medicaid balks at paying for it."
- JUST...
- Taken for less than 1 month
- September 11, 2022
For Nausea/Vomiting "I've been traveling and taking Zofran. In the past if I took Zofran once, it seemed to be okay. But after taking multiple doses, these last few days of travel, I've been having nausea, vomiting, diarrhea, muscle spasms and numbness/tingling in my limbs. When I would feel a little off, I would take Zofran not realizing that it was making things worse for me!!! I also looked up any possible drug interactions and it appears that it has a major negative interaction with Zoloft (which I take!). It's ruined the first part of my trip and I'm praying that I can start feeling better so I can enjoy the trip that I have dreamed about for decades now!"
Are you taking this medicine?
- Abby
- Taken for 1 to 2 years
- December 26, 2021
For Nausea/Vomiting "I have been suffering with cyclic vomiting syndrome for around 5-6 years now and zofran is the only thing that works. My nausea and vomiting is so severe that I do need to take double the recommended dose, however it does work. I have never had a single side effect from Zofran. I understand this drug might not work for some people, but for me it is great!"
- Lila...
- April 27, 2017
For Nausea/Vomiting "First time I took it I felt better almost instantly- it was truly crazy! The second time was the same but the third time it didn't help as much. However, it helped some and has so far kept me a little less feeling like I'm gonna puke. Better than nothing."
- Anonymous
- April 20, 2012
For Nausea/Vomiting "I am/was taking this medicine to combat nausea from post chemo treatments and I found that it did give me a headache and I could not stand the taste it left in my mouth when the medicine disintegrated on my tongue. "
- Gastr...
- Taken for 1 to 2 years
- May 20, 2017
For Nausea/Vomiting "I use this when I am driving and have nausea and was under doctor's instructions to take it twice a day until I was prescribed the scolopamine patch for nausea. Now, I just take it on the times I feel nauseated with the patch, which is not much. I like the dissolvable tablets because they are quicker than the pills to absorb and I can just carry them with me in my purse, unlike the phenergan suppositories, which have to be refrigerated or kept in a cooler when going somewhere."
- Anonymous
- Taken for 6 months to 1 year
- November 30, 2021
For Nausea/Vomiting "Zofran is a miracle drug for me. I always have some on hand. I suffer from GERD, IBS, gastritis, malabsorption, endometriosis, and the list goes on. Nausea is a nagging symptom that I have often, and I vomit on a regular basis. Zofran has kept me out of the ER on many occasions due to severe vomiting. It also gets me through the occasional rounds of antibiotics as they really mess with my stomach. It does cause some pretty bad headaches when taken on a regular basis, but I will take a headache over vomiting any day. Could not recommend enough! It has been a total lifesaver!"
- Tori
- Taken for 2 to 5 years
- March 1, 2024
For Nausea/Vomiting "I take Zofran as part of my treatment for panic disorder that often causes nausea. This drug has never failed me. It always cures my nausea within an hour, and I've never thrown up while taking it. Only problem is it makes me constipated, and sometimes gives me a headache."
- MDDMom
- Taken for 10 years or more
- December 13, 2021
For Nausea/Vomiting "Frequent migraines and Cervicogenic headaches often make me extremely nauseous, which subsequently may cause me to vomit, not a good occurrence with massive headaches. I’ve also had intractable vomiting, and received zofran IV or suppository (effective but unpleasant). I’ve tried other anti nausea medications to little effect. 1 dissolving tablet at the onset of pain-related nausea works extremely well for me. In over a decade of taking it (including while pregnant) I’ve had no side effects despite being on a number of medications."
- LilMi...
- Taken for 10 years or more
- February 1, 2024
For Nausea/Vomiting "I have taken Zofran for migraines and cyclical vomiting syndrome for nearly 2 decades. The last 8 years, I have taken it daily. It worked wonders for several years, however, my health has rapidly declined from chronic illness and a couple of autoimmune disorders. Now, when I take it, I throw up in a matter of minutes. I'm wondering if I'm reacting badly because I've taken it for so long? I think I'll talk to my doctor about stopping it for a while to see if it's causing me more trouble than it's worth. Overall, it worked wonders for me for 10-15 years. I'm deducting points for taste and possible long-term side effects."
- Bre...
- Taken for less than 1 month
- April 23, 2022
For Nausea/Vomiting, Postoperative "I was prescribed this drug a few weeks back when I had an upper respiratory infection. The coughing fits got so bad they would make me throw up, and I had post nasal drip and the mucus made me feel sick to my stomach constantly. My Dr gave me this to try, because I couldn't really eat anything, and it works like a charm. 30 minutes after taking the ODT, I'm able to eat with no issues. I still have some left over from my URI, and I keep it on hand just in case. It's wonderful to have. I didn't have any side effects besides a slight headache, but it was completely worth it to finally be able to stomach some food and not have to get up 4 or 5 times a night feeling like I had to throw up."
- Disso...
- Taken for less than 1 month
- November 22, 2021
For Nausea/Vomiting "I took ondansetron swallow-pill at 4mg and it was starting to help. My physician increased the dose to 8mg but it was now a mouth dissolving-format and made my nausea FAR WORSE. Pharmacy says the can distribute 8mg in the swallow pill form, but the doctor has to prescribe it in that format."
- Stomach...
- Taken for less than 1 month
- January 8, 2022
For Nausea/Vomiting "Took for a few days after getting food poisoning which turned into a stomach virus. It worked for a hour or two, but the nausea came back worse. No vomiting surprisingly but didn’t really help my nausea."
- Bjcg
- Taken for 1 to 6 months
- December 27, 2016
For Nausea/Vomiting "The directions say to dissolve in the mouth but it's very bitter. Does anyone else have this problem?"
- Erynnj
- August 19, 2014
For Nausea/Vomiting "Only thing that works! I have MSK and vertigo and BOTH cause nausea with flare ups and this is my life saver!"
- Chantel
- August 18, 2016
For Nausea/Vomiting "This medicine did nothing except constipated me and give me a headache!"
- Googe
- July 10, 2016
For Nausea/Vomiting "Had kidneys stone. Took pain meds for it. Got super nauseous at night. Took zofran, and within 10 minutes I was not nauseated at all. Amazing medicine."
- Lithh
- Taken for 2 to 5 years
- April 19, 2016
For Nausea/Vomiting "Best nausea medication in my opinion. I use it for nausea associated with my migraine headaches and it works extremely fast and well."
- Wingnut
- July 29, 2019
For Nausea/Vomiting "I have nausea and vomiting from the flu and this medication either did nothing or made me more nauseous."
- wrecky
- Taken for 2 to 5 years
- October 17, 2014
For Gastroenteritis "Oral Dissolving Tablets are the way to go. It is quite discouraging vomiting up your nausea medicines."
- Hatchet
- Taken for less than 1 month
- August 21, 2018
For Nausea/Vomiting "Works well with me. Stopped my nausea and vomiting right away"
- Evilm...
- Taken for 6 months to 1 year
- October 9, 2018
For Nausea/Vomiting "This medication is amazing! The dissolving version is so convenient and I can carry 1 part of a blister pack in my wallet."
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
More about Zofran ODT (ondansetron)
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- During pregnancy
- Generic availability
- Drug class: 5HT3 receptor antagonists
- Breastfeeding
For Nausea/Vomiting "I get debilitating migraines that cause vomiting, and I have several GI issues, my doctor ordered zofran pills to begin with and they did nothing for me. Although I still feel a little nauseous at times I can stop the vomiting with the zofran ODT by putting it under my tongue."