Zofran ODT and Vomiting: What Users Say

• Wil...
• September 23, 2013

For Nausea/Vomiting "I suffer from chronic lower back pain due to scoliosis and arthritis (42 yrs old). I also suffer from irritable bowel syndrome. I take Zofran almost daily to deal with the miseries of both lower back pain and digestive issues. I still have regular bouts of vomiting, however, Zofran will stop the pain and nausea that would continue for days and land me in the hospital with an IV delivering morphine into my system to stop the cycle of vomiting, nausea, and severe pain. I love my Zofran! It makes life 'livable.'"

• Cat...
• Taken for less than 1 month
• February 22, 2021

For Nausea/Vomiting "Horrible drug for me. Actually makes me nauseous and throws up. Nothing tastes right on this medication. One dose had me throwing up and nauseous, not able to eat for a couple of days. One dose had me constipated for about 5 days before I was back to normal (with taking stool softeners Rx after surgery). May work for some, but for me, it’s a NO go."

• Mrs...
• January 11, 2013

For Nausea/Vomiting "I have severe nausea and vomiting due to an extreme case of endometriosis. I have to be hospitalized because of pain, weakness, and dehydration because of severe vomiting. I can't even hold down a tiny sip of water for 2 minutes. I have tried every medication possible, and Zofran ODT is the only thing that gives me relief! It is a prescription I always have on hand at all times."

• Anonymous
• April 5, 2010

For Nausea/Vomiting "I must say I don't have cancer, and I don't have a disease, I have a spasmodic colon, which in turn gives me a severe case of Irritable Bowel Syndrome with constipation. I usually have a bowel movement every 6-11 days, and when I do, I get extremely ill with uncontrollable vomiting due to the pain. I've tried several non-dissolving medications, and I've found that Zofran ODT (8 mg) is the best, and I will stick with it as long as it continues to work for me. I hope someone finds this helpful. If you have any form of illness that causes severe vomiting, I recommend Zofran ODT."

• sil...
• Taken for 1 to 6 months
• September 18, 2012

For Nausea/Vomiting "I am pregnant and have been suffering from severe nausea and vomiting. I have been taking Zofran for about 25 weeks. The dissolving tablet doesn't have an effect on me. I can't keep it down, even after half an hour, I will throw up the medication. The rare times I can hold it down, it has no effect on me."

• Oak...
• August 2, 2017

For Nausea/Vomiting "I take Zofran ODT to relieve the severe medication withdrawal symptoms I experience when I accidentally miss a dose of my prescribed daily medication. Severe medication withdrawal symptoms such as brain zaps, nausea, vomiting, headaches, and dizziness."

• Lit...
• Taken for less than 1 month
• December 12, 2016

For Nausea/Vomiting "I was rxed the ODT for extreme nausea and vomiting, due to a norovirus. The minty flavor really drove me over the edge and only made matters worse. Then my doc gave me the regular tablets that you swallow with a tiny bit of water, but it didn't help at all either. I remember being awed by the knowledge that they give this med to sick cancer patients when it is so horribly ineffective. Evidently, it does work like gangbusters for some people, but I'm not one of them."

• JUS...
• Taken for less than 1 month
• September 11, 2022

For Nausea/Vomiting "I've been traveling and taking Zofran. In the past, if I took Zofran once, it seemed to be okay. But after taking multiple doses these last few days of travel, I've been having nausea, vomiting, diarrhea, muscle spasms, and numbness/tingling in my limbs. When I would feel a little off, I would take Zofran, not realizing that it was making things worse for me! I also looked up any possible drug interactions, and it appears that it has a major negative interaction with Zoloft (which I take!). It's ruined the first part of my trip, and I'm praying that I can start feeling better so I can enjoy the trip that I have dreamed about for decades now!"

• wre...
• Taken for 2 to 5 years
• October 17, 2014

For Gastroenteritis "Oral dissolving tablets are the way to go. It is quite discouraging vomiting up your nausea medicines."

• Mad...
• March 12, 2023

For Nausea/Vomiting "I took this for a bad stomach bug, and it actually made me feel worse. I wish it had worked for me, but I got extremely nauseous to the point of vomiting. I’ll stick with Phenergan."