Skip to main content

Niacin and Joint Pain: What Users Say

Brand names: Niaspan, Vitamin B3, Slo-Niacin, Heliocare Advanced, Niacor, B-3-50, B3-500-Gr Niacin SR NiaVasc Endur-acin HDL Benefit …show all brand names

Joint pain: mentioned by 3 users (2.6%)

Based on user experiences from 117 Niacin reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

flushing 31.6%
itching 7.7%
burning 6.0%
rash 6.0%
anxiety 4.3%
depression 3.4%
acid reflux 2.6%
headaches 2.6%
joint pain 2.6%

Reviews for Niacin

Commonly mentioned side effects
  • pri...
  • Taken for 2 to 5 years
  • April 23, 2013

Niacin for High Cholesterol "I take 1000 mg two times a day. Taking 325 mg of aspirin before I take the Niaspan helps with the flushing. I have been on Niaspan for about 3 years now, my numbers are down 10%. The little bit of flushing I do get is a lot better than the severe joint pain I had with the statin medications. I recommend taking Niaspan. It is working for me."

9 / 10
Was this helpful?YesNo
40 Report
  • Jan...
  • Taken for 5 to 10 years
  • February 27, 2019

Niacin for High Cholesterol "I have been taking Niaspan 2000 for the last 8 years with okay results. But the last time I went to the doctor, my cholesterol was 220. The doctor put me on Zetia since I cannot take statins. Unfortunately, Zetia had the same reaction on my body as statins: terrible joint pain. After only 10 days, I had to stop. I was hoping it would be the answer, but it wasn't. I went back on Niaspan. I watch what I eat and have been a vegetarian for 45 years. The doctor said it was hereditary that my liver makes too much cholesterol and it was not my diet. I am at the end of my rope now if the Niaspan stops working. Suggestions?"

7 / 10
Was this helpful?YesNo
6 Report
  • COM...
  • Taken for less than 1 month
  • October 8, 2017

For High Cholesterol "I have been taking niacin ER for about 2 weeks and have many headaches at night and waking up all times of the night due to pain. I am on CPAP also, which I think does not help. Plus, joint pain during the day. I just don't like the feeling with this drug."

2 / 10
Was this helpful?YesNo
2 Report

See also:

Frequently asked questions

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.