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Misoprostol and Vomiting: What Users Say (Page 2)

Brand names: Cytotec

Reviews for Misoprostol

Commonly mentioned side effects
  • jrs...
  • Taken for less than 1 month
  • May 20, 2021

For Abortion "6 weeks pregnant. I was terrified and had worked myself up about this all week, but it wasn’t as bad as I thought. 9:30 am: Took 60 mg codeine, 500 mg paracetamol, and 200 mg ibuprofen. 10:15am: Took misoprostol 37 hours after the first pill. Threw up straight away. 10:45am - 11:30am: Intense, painful cramping and more throwing up. I have had very bad periods which were similar to this pain, though. 11:45am: Cramps completely stopped (so just 1 hour of pain). 1:45pm: Went to the toilet to check for bleeding... nothing. Was thinking it hadn’t worked. 1:50pm: Sat on the toilet again and I had started bleeding, felt something come out down there (weird sensation but not painful). I looked in the toilet and saw a small grey sac. It was done. 3:15pm: It’s been 1.5 hours since I passed the pregnancy and have felt completely fine. Overall, although not pleasant, at least I could be in my own home and it was just 1 hour of pain, and it was all over faster than I thought."

8 / 10
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  • Cca...
  • Taken for less than 1 month
  • December 15, 2020

For Abortion "I was 7 weeks and 1 day. First, I took the mifepristone in the office and got a little nauseated, but that’s all. The doctor then told me to insert 8 misoprostol vaginally by the time I went to bed that evening. I ate, and I took Tylenol with codeine 30 minutes before I inserted them. An hour went by, and I was in pain, but definitely tolerable, but it intensified along with shivering really bad, so I got in the bath. I then threw up all the food I ate, but felt tons better, but was still shivering and started to bleed. I finally went to lay down, and my boyfriend got me a heating pad and helped me a lot. I fell asleep due to medication, then woke up an hour later with pretty bad cramping. Passed some clots and tissue and felt much better. It’ll be okay, ladies, promise."

10 / 10
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  • Swe...
  • Taken for less than 1 month
  • August 17, 2019

For Abortion "I was about 5-6 weeks pregnant, and it was just not the right time for us to have a child. On Thursday, I took the first pill at the clinic, and Friday night I started to bleed very lightly. On Saturday morning, I took the Tylenol and the anti-nausea pills 30 minutes before the second pill, about 10 a.m. At 10:50 a.m., I started not feeling well and went to get up to go to the bathroom. The second I got up, I was in agonizing pain! I then spent the next hour and a half in the bathroom with diarrhea and extreme pain that had me howling. Tylenol with codeine did not help. I ended up throwing up a few times from the pain. I tried to get up to go lay down in the bed and couldn’t even stand up straight, and the cramps came every minute to minute in agony. This continued until about 1 p.m. when I had a painful contraction and felt oozing come out. Now it’s 1:22 p.m., and I don’t have the excruciating pain and just feel as if I have a normal period. Hope to never go through this again."

9 / 10
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Frequently asked questions

  • Maj...
  • August 11, 2019

For Abortion "I was 7w3d when I took the 4 pills. I took 800 mg ibuprofen 1 hr before taking the pills. They began dissolving in my cheeks, and I got mild cramps, but after the 30 min when you swallow the remainder with water, the pain escalated DRASTICALLY, and all I could do was moan, cry, and rock in pain. I have never in life felt pain like that before, and I have tattoos on my ribs on both sides! I was shaking and felt myself trying to vomit, but I didn't let it happen because I was afraid I would vomit the meds. After about 30 min of agony, I felt the urge to sit on the toilet. I passed 3 large clots and lots of blood, that is when the pain minimized to normal period cramps. I fell asleep for a couple of hours, and the bleeding continued along with the passing of smaller clots. I gave it a 10 because it works, and it's super convenient to be at home, but beg your doctor to prescribe you something stronger than ibuprofen for the beginning cramps because it's unbearable!"

10 / 10
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  • Ano...
  • Taken for less than 1 month
  • October 16, 2021

For Cervical Ripening "I inserted two 200 mg tablets vaginally 8 hrs before surgical hysteroscopy for an endometrial polyp. This turned into one of the most traumatic experiences of my life. Pain started abruptly within 45 minutes, and it was agony. I tried taking pain meds but vomited them up almost immediately and then vomited continuously for 4 hours (mostly dry heaving as I was empty). Badly dehydrated. Severe shivering/chills. When I arrived at the surgical center, I collapsed on the floor of the lobby. It took a LOT of preoperative medication to get my pain/symptoms under control enough to do the surgery, and they had to switch from sedation to general anesthesia. When I woke up, the same terrible pain was still there, and I was maxed on narcotics before I was stable enough for discharge. Now, 12 hours later, the pain is manageable but not gone, and I’m incapacitated by pain, meds, exhaustion. The good news is the surgery was a success (a previous attempt w/out failed and created a false passage)."

3 / 10
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  • Gon...
  • November 23, 2019

For Abortion "Okay, so the thing is, EVERY WOMAN'S BODY IS TRULY DIFFERENT! Please do not watch these reviews and expect all of these things to occur or not occur through your experience. I will speak on my personal experience. So, I was 8 weeks pregnant when I took the pill, and after dissolving it in my cheeks, I immediately felt cramps. I’m talking about like the minute I actually swallowed. I had period-like cramps that were bearable for like 5 minutes, and then they started to intensify, so I went to the restroom to try and poop, and literally nothing helped how vicious the cramps quickly began to get to the point I was literally yelling, hitting, crying for it to just stop! Also, I threw up like 10 minutes after taking the pill, and IT STILL WORKED! So if you throw up after swallowing, it will still be effective. That extreme pain lasted for no longer than 20 minutes tops, then it began to slow down and become bearable again."

10 / 10
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  • CC0...
  • Taken for less than 1 month
  • September 25, 2023

For Cervical Ripening "The reviews here are unsettling, but after a horrific, barbaric, excruciating endometrial biopsy a couple of years ago, I was willing to take a chance. So glad I did - very minor reaction with a much less painful experience. I have not been pregnant before and am 52. No dilator needed. Here’s how I prepared: 1. Ask for a prescription for 1 or 2 Zofran or similar to stop vomiting, just in case. 2. Clean the toilet, just in case. 3. 1-2 hours before taking the misoprostol, take ibuprofen or whatever the doctor recommended. I took 800 mg and a leftover tramadol. I wanted the meds to get in my system in case I started vomiting. 4. Get your area comfy and ready for the worst: trash can, towel, clear way to the toilet, etc. 5. Take the misoprostol. I was prescribed 2 and inserted them vaginally the night before. 6. After an hour, I felt mild cramping, but that was it. Woke up and took more ibuprofen and a tramadol. An hour before the biopsy, I took Valium the doctor prescribed."

10 / 10
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  • Cyt...
  • July 23, 2021

For Cervical Ripening "My Dr. recommended this prior to an IUD insertion. Within 30 mins of vaginally inserting the 4 pills, I was throwing up on the side of the freeway. I had cold sweats, non-stop vomiting, diarrhea, and the worst cramping I’ve ever had in my life. I ended up at the ER to get pain medication and an IV as I quickly got dehydrated and couldn’t hold down any liquids. (Heads up - this medication is also used to terminate pregnancies, so the ER staff kept on asking me if I was trying to have an abortion.)"

3 / 10
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  • Iri...
  • Taken for less than 1 month
  • March 31, 2023

For Abortion "I am 33, and this was my first time using the abortion pills. I want to give an honest account for ladies to prepare for the same scenario. I took the first tablet at 3 pm on Thursday. I had zero side effects and was able to carry on with my usual routine. I inserted the 4 Misoprostol exactly 24 hours later at 3 pm on Friday (I took pain relief 10 minutes before this). I lay down on the bed and waited for them to take effect. At 3:30 pm, I started to feel mild cramps. At 4 pm, these turned to moderate cramps. At 4:30 pm, I vomited 4 times and had diarrhea, then the cramps suddenly became very painful. I sat on the toilet for 90 minutes in a lot of pain, with very heavy breathing, before I felt a sudden woosh, which was the sac passing at 6 pm. I ate a banana at 6:20 pm and took the final two oral tablets with mild cramps for the rest of the day. The entire process was over within 3 hours, with only 90 minutes of bad pain, so it was absolutely doable and worth it."

10 / 10
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  • Poo...
  • Taken for less than 1 month
  • January 14, 2020

For Abortion "I took these tablets today at home as advised by the clinic. I was expecting very moderate pain akin to period pain - I was so wrong. I had about three hours of utter agony, shaking with pain, vomiting, and having to bite down on something to stop me from shouting every time the cramps came on (every two minutes). I think the clinics should really keep people in to monitor them, as I have never been in so much pain in my life. Had I known it would be so painful, I would have opted for surgical, as this method without the proper pain relief is just not acceptable."

5 / 10
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  • imo...
  • Taken for less than 1 month
  • September 2, 2021

For Abortion "I was about 8 weeks. I took the first oral pill on the Monday. This was absolutely fine, there was no pain or bleeding. Twenty-four hours after, on the Tuesday, I inserted the misoprostol vaginally, I then took two ibuprofen. I waited, lying down, and in about half an hour, I started to feel cramping. In the next half an hour, the cramping got extremely painful. I threw up once, and I then took 4 codeine and lay in bed. The pain eased about half an hour after taking the codeine. About half an hour later, I started bleeding very, very heavily. I went to the toilet, and I felt two clots pass, I was quite certain it was the pregnancy. Although I had already felt the pregnancy pass, 4 hours later, I inserted the two leftover misoprostol in my gum and let them dissolve. I swallowed what didn’t dissolve half an hour later. The pain was like normal period cramping for the rest of it. I am now not pregnant. You can do this, girls, I promise x."

10 / 10
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  • Pop...
  • Taken for less than 1 month
  • November 8, 2022

For Abortion "After reading so many horrendous stories about other people's experiences, I was really nervous and worried for this treatment, however, it was not as bad as I thought it was going to be. I took the treatment as I was 5 to 6 weeks pregnant. I bled within 45 minutes of inserting the 4 tablets, and I didn’t have any vomiting or diarrhea after I took them. I took 2 x codeine as instructed and had mild to severe cramping for a few hours. I have pretty heavy periods and usually pass blood clots, so it was similar to a heavy period for me. I felt I passed the pregnancy within 4 to 6 hours and continued to bleed light to moderately for 12 days. I then did a low HCG pregnancy test 3 weeks after taking the tablets, and it was negative. I was so relieved it worked and it wasn’t as horrific as some people said, however, everyone is different. A heating pad definitely helped."

10 / 10
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  • Nip...
  • Taken for less than 1 month
  • May 10, 2023

For Abortion "So I too was very scared and worried after reading some stories about vomiting, diarrhea, and terrible cramping. To prep, I took 2 Motrin (200 mg each) and 1 anti-nausea pill that my gynecologist gave me about 30 minutes before. I decided to insert the pills vaginally because I was hoping it would help me avoid stomach issues. The misoprostol started taking effect about 30 minutes after, to my surprise. My cramps started feeling like constipation pain, and so after a while, despite having a heating pad and the two Motrins in me, I decided to go to the toilet hoping to find relief. I ended up staying on the toilet for 1.5 hours but did not release anything other than blood and clots. Within that 1.5 hours, the cramps died down, and I actually felt pretty normal, like I was having a regular period. I was so happy and surprised that the worst was over that fast! I’m here writing this after leaving the toilet just to say, do not fear the second pills. You are stronger than you think!!"

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • June 25, 2019

For Abortion "The pills definitely worked, which is why I gave it a high rating, but my experience was horrible. I got really bad chills and started itching on my arms an hour after taking the 4 pills by mouth. Then came the diarrhea with extreme thirst and unbearable cramping. It was about 2 1/2 to 3 hours in by the time the vomiting started. My pain tolerance is very high, but this was too much pain at once. The pain pills did absolutely nothing. I started at 10 pm and didn’t completely finish until around 7:30 am. I don't recommend this method, although it’s very effective, it just wasn’t a good choice for me."

10 / 10
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  • Str...
  • Taken for less than 1 month
  • April 6, 2019

For Abortion "I am not sure if the drug worked yet. The side effects were not bad. The first hour and a half were usual period cramps. Then I started to have really intense cramps, vomiting, and chills. The one thing that helped me a lot was sitting in a warm bath. I’m not sure if it’s helpful at all, but I found it very relieving of the pain and much easier to pass the clots. I took gravel an hour afterward, and it helped with the nausea. Overall, I would definitely recommend the pill to someone who can handle pain and blood. I have been using a heating pad most of the time, and it helps so much. I don’t know how I would have handled everything without it. My best recommendation would be to sit on the toilet and let as many clots pass in the first hour, and then place a heating pad over your stomach until the pain subsides. The severe pain lasted one hour for me, and I’m feeling a lot better now. I took two T3s two and a half hours before I dissolved the pills in my mouth."

10 / 10
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  • Gha...
  • January 7, 2021

For Abortion "I was pregnant in the 8th week, and I had a really hard time. I had a medical abortion. I took Mifepristone at the clinic and Cytotec two days later intravaginally at home. I had no bleeding at all after Mifepristone, but I felt really sick two days after and I started to vomit. I took the Cytotec 40 hours after the Mifepristone. Before taking the Cytotec, I took 4 tablets of paracetamol and 2 tablets of 50 mg diclofenac based on the doctor's recommendation. I inserted the 4 Cytotec tablets deep in the vagina. Then I started to experience a very unpleasant moderate to severe pain. 40 minutes after taking the Cytotec, I took 5 mg oxycodone, but I threw up 20 minutes after. One hour after the Cytotec, I started to bleed. Two hours after the Cytotec, I felt like some clots and tissue were being expelled from my body (I was sitting on the toilet). I felt a lot of relief after that. The pulsating pain of Cytotec lasted for at least 10 hours. I used a hot bag to ease the pain."

10 / 10
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  • Sky...
  • June 7, 2019

For Abortion "I was 8 weeks and a couple of days. I’ve been reading different stories and was really scared. I took the first pill in the office. 48 hours later, I took the 4, maybe 40 minutes later the pain kicked in. I have a high pain tolerance, but this pain I was feeling was so horrible!! Nothing helped. I took pain pills before and everything, the heating pad didn’t work. I threw up and pooped at the same time. Blood started coming 2 hours sitting on the toilet, and clots started coming out."

8 / 10
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  • No ...
  • May 21, 2016

For Abortion "Had to take this medicine because I wasn't able to find a heartbeat. It was the worst pain I've experienced. My doctor had prescribed me some strong painkillers, and it did nothing. I was throwing up and had diarrhea. I was so weak, nauseous, and in such pain. I was freezing and shaking so much. I felt a bit better when I finally went into a hot bath. But then trying not to fall asleep and drown. I hated every second of it. If I had to choose again, I would probably do a D&C, but I guess it is different for everyone."

3 / 10
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  • Tya...
  • August 7, 2021

For Abortion "I was about 8 weeks. I’m still going through the process right now. I just want to tell anyone that’s doing this that you got this, and you’ll get through this. I took my pills around 2:30, about 2 hours ago. A few minutes after I took them, I experienced cramping that for me was very painful. I do believe that it depends on your pain tolerance. I hadn’t had a period in so long due to my IUD, so the cramps were strong. I threw up twice, no diarrhea yet. I also passed 2 blood clots, one which I believe was the pregnancy, but I was too scared to look. I’m still mildly cramping, and it is uncomfortable, but it’s almost over. I also did experience the shivers. I did all of this by myself on my bathroom floor with two pillows and a blanket to try to comfort myself as best as I could. Just remember why you’re doing this and that you’re making the best decision that you feel for your life. You’ll get through it."

6 / 10
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  • Adx...
  • Taken for less than 1 month
  • September 2, 2021

For Abortion "I took the mifepristone and went to bed. The next night I had light spotting, no cramping. Spotting continued lightly into the next day, and at 8:35 I took a Tylenol 2 with codeine. At 9:20 that night, I inserted 4 misoprostol vaginally and rested for an hour to allow the medication to dissolve. At 9:50, the cramping started. Mild period cramps, a 4/10. This progressed until 11 when the pain rose to about a 6/10. No bleeding. At 11:35, the pain is around an 8/10. I took another Tylenol 2. Chills and vomiting at 12. Pain is now 10/10 (after vomiting pain pills), cramps lasting 20 seconds, every 20 seconds until 2 am. Pain now 15/10, debating ER. At 2:30, horrible cramping. Passed several large clots quickly and a lot of blood. Pain and nausea gone, mild cramping and heavier bleeding continued. Pill effective, however, make sure you have pain medication that is working!!! Maybe your experience won't be as painful, but the medication worked. 5.5 hours until it passed. Mildly uncomfortable with light bleeding days after."

7 / 10
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  • Lov...
  • Taken for less than 1 month
  • August 15, 2021

For Abortion "I decided to terminate my pregnancy at 8 weeks. I’m going to be completely and brutally honest with you ladies. I got to the clinic around 7:45 am and took the pill at 8:32 am. The doctor assured me that I wouldn’t experience any bleeding or cramping until I inserted the four pills that he gave to me around 2:32 pm. I went home and inserted the pills vaginally around 6:45 pm and was only experiencing light bleeding with no pain - but OMG after 2 hours passed, it kicked in. The pain was excruciating. I would also recommend not eating anything before inserting the pills vaginally because you will vomit violently! After going through it from 7:45 pm - 10:45 pm, I went to the restroom, and clots the size of lemons gushed out into my shorts, and I pushed what was left over into the toilet. This was a traumatic experience for me to say the least. I’d rate the pain 8/10. I gave 10 stars because it worked."

10 / 10
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  • Mad...
  • Taken for less than 1 month
  • March 4, 2021

For Abortion "I was 7 weeks and 5 days when I went to the clinic. I was so scared after reading all the reviews. I took the first pill at 12:45 in the afternoon in the clinic, and as soon as I got home, I dry heaved twice from it. The next day, I took my 800 mg of ibuprofen, nausea pills, and my 300 mg of Tylenol codeine 30 minutes before the 4 pills. Once it was time, I put the pills under my tongue to dissolve. I didn't feel any cramping or bleeding until an hour and a half later. I barely had any cramping. Within 30 minutes to an hour, I had passed the fetus and blood clots pain-free. Every woman is different. Don't believe all the negative reviews because they had me worrying during the night where I couldn't sleep. Just take the pain meds beforehand, have a support person with you, and a heating pad, and you will do great!!"

10 / 10
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  • Ali...
  • Taken for less than 1 month
  • November 12, 2020

For Abortion "I had a missed miscarriage, and needed to get rid of the product of the pregnancy. I would not recommend this drug, misoprostol, to anyone as it was very hard on my body. I had a missed miscarriage, and the doctor would not perform a D&C on me due to COVID. About 4 hours after insertion, I started bleeding uncontrollably, I was passing out and vomiting. The pain was unbearable. I was rushed to the hospital in an ambulance as the hemorrhaging worsened. I had to have an emergency D&C and a blood transfusion. I became anemic, and it took me weeks to recover."

1 / 10
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  • Meg...
  • Taken for less than 1 month
  • June 1, 2023

For Abortion "I was 6 weeks pregnant and decided to go with abortion pills. Yesterday, I took one pill at the doctor's office, and today I took 4 more pills in between my cheeks (and two Tylenol 30 minutes before). The whole process took 4 hours. After an hour, I started to have bad cramps and pain in my lower back. Then I had diarrhea 3 times. After about 2 hours of taking pills, I went to the washroom, and a large blood clot came out. It was the size of a bottle cap. Then the pain of the cramps increased, I felt nausea and did vomit one time only. After that, I felt relieved, the pain was gone and I felt much better. It is a painful procedure, but it only lasts 4 hours. Hope this helps!"

9 / 10
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  • HER...
  • April 1, 2023

For Abortion "I was 6 weeks and 2 days pregnant and took the first pill at the clinic at around 11 a.m. I threw up an hour later but was instructed by the doctor to take misoprostol anyway. The next day at noon, I took the pills orally (2 in each cheek). After about an hour, I started getting the cramps and along came the bleeding. After another hour is when I got diarrhea. Other than that, I would say the pill is not as bad as other people say. The cramps were tolerable enough. Don’t overthink this, you’ll be fine."

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.