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Misoprostol and Cramps: What Users Say (Page 5)

Brand names: Cytotec

Reviews for Misoprostol

Commonly mentioned side effects
  • Des...
  • May 3, 2020

For Abortion "7 weeks and 2 days. Took the 1st pill at the office and had no side effects, and then the next 24 hours I was given promethazine for nausea and ibuprofen for pain. I also had heating wraps on standby. Took my pain meds and nausea meds 30 minutes before, and then I did my 4 pills by mouth and swallowed. After 30 minutes, probably about 10 minutes after, I felt mild cramps, lighter than my usual period cramps. I automatically got sleepy from the promethazine and felt really relaxed. My cramps were so light I didn't have to take any more pain meds, but I still take ibuprofen to help with the bleeding. My 1st trip to the bathroom, I passed a blood clot the size of a half dollar and came back to bed. I went on and changed my pad to stay fresh, and during me laying down, I felt like I had to have a bowel movement. I went to the bathroom again, and this time I could feel something trying to come out of my vagina, so I pushed a little bit, and a blood clot as big as a lemon came out."

10 / 10
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  • Hol...
  • January 10, 2020

For Labor Induction "At 8 weeks, we went in for our scan and unfortunately, there was no heartbeat. My doctor told me to take this medicine or a D&C. I picked this drug because I wanted to be at home when the tissue passed. I took tramadol 50 mg and ibuprofen 600 1 hour before starting the misoprostol pills. Within 30 minutes, I started bleeding lots of clots. Was fine until maybe 2.5 hours after taking the medicine. It was honestly the worst pain I have ever had. I had vomiting, sweats, shakiness, and extremely painful cramps. I was in so much pain I started making so much noise that the lady in the condo beside me came to see what was happening. If I knew I would have had so much pain, I would have had a D&C. However, after about 6 hours after taking the pills, the pain started to calm down. I found that once all the clots and placenta came out, the pain started to go away and just turned into a heavy period. If you are taking it for the same reason I did, I pray you don’t have the same experience I did. I am very sorry for your loss :( ❤️"

5 / 10
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  • Tif...
  • January 26, 2020

For Abortion "Most people talk about bad experiences, but very few y’all about positive or neutral ones. This morning at 8 a.m., I took 2 ibuprofens, 1 Panadeine (codeine and acetaminophen), and an anti-nausea pill. Then at 9 a.m., I put the two pills in my cheeks for 30 minutes before swallowing the remainder. My throat was sore immediately after. I lay in with my heat pack, and about 30 minutes in, I started to get cramps - they were unpleasant but nothing intolerable - then started to bleed lightly. The bleeding stayed light until around 11 a.m. when I went to the bathroom and passed a smallish clot. After that, my cramps got a little worse, the bleeding got heavier, and I continued to pass clots. At around 1-2 p.m., I passed the largest clot, and after that, my cramping reduced significantly. The bleeding continued to be heavier than anything I’ve ever experienced before, but I guess that’s to be expected - a normal period is like three weeks of lining, whereas I’m around seven weeks. Stay strong, rest up, and it will be over before you know it."

9 / 10
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Frequently asked questions

  • Max...
  • Taken for less than 1 month
  • July 3, 2016

For Abortion "I used this in conjunction with mifepristone, and 48 hours later took misoprostol by dissolving 4 pills on the inside of my cheeks. I started at 4 p.m., waited for the pills to dissolve in my mouth for 30 min, and swallowed the rest. I experienced nothing and fell asleep on my couch. I woke up drenched in a cold sweat and mild cramps at 6:15. I got up and immediately threw up. My nausea continued throughout my whole ordeal. By 8 p.m., the pain was excruciating, I felt all my lower torso contorting from my belly button to my upper thighs. The best way I can describe this is full-term labor contractions. I got dizzy, and my husband gave me a hot shower. I lost consciousness for a min or 2. By 10 p.m., I passed the baby, and it was smooth sailing again."

9 / 10
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  • Ayo...
  • Taken for less than 1 month
  • November 20, 2021

For Abortion "Guys, I was 3 months gone. I used this drug for abortion, and after 2 hours, I started feeling pain, just like normal cramps, and I started bleeding heavily, though it wasn't painful as expected. Like 30 minutes later, heavy blood clots started coming, and later, the product itself came out. After a week, I did another test, though I'm still bleeding, it says it is positive. What do I do?"

1 / 10
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  • yog...
  • May 19, 2021

For Abortion "I told myself that I would write a review about my experience so other women would know of one good experience with Misoprostol. I was 5 weeks pregnant at the time. I took the Mifepristone at 3:30 pm on the first day. I experienced some bleeding within 24 hours. I inserted the 4 tablets vaginally at 5 pm the next day after taking 800 mg of Ibuprofen. After about 3 hours, I began feeling some slight cramps, so I took one Tylenol 3 and used a hot water bottle to soothe the oncoming cramps. About 4.5 hours after inserting the pills, I began experiencing nausea and strong cramps. The cramps and nausea were uncomfortable but very manageable. After about 6 hours, nausea stopped, but I had some cramping, so I took pain relievers and went to sleep. I had some heavy bleeding for 7 days (it was heavier than a period with more clots than normal), but nothing horrifying. My bleeding stopped completely after 7 days. I get that everybody is different, but I hope this helps you if you are feeling very anxious."

10 / 10
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  • DHa...
  • Taken for less than 1 month
  • September 26, 2020

For Cervical Ripening "I've had this twice, vaginally, 20 years apart. First time I was 19, and it was to soften my cervix before a termination of pregnancy. I remember having very painful cramps, like contractions. Then I had it again today (I'm now 40) to soften my cervix before an 'evacuation' surgery (suction) to remove everything after a missed miscarriage. They put 2 tablets high in my vagina and left them in for 5 hours by the time I got to the theater, and I had some occasional short cramps, but they weren't bad at all, and I was able to breathe through them and didn't need painkillers. So I've had two quite different experiences (in two quite different situations). Good luck, ladies x"

9 / 10
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  • tay...
  • January 17, 2021

For Abortion "I’m 18 and got pregnant for the first time. I freaked out and knew right away I couldn't have it. On Day 1, the nurse gave me an antibiotic and then the Mifeprex. With this, I had no symptoms and felt normal. On Day 2, I took the misoprostol orally (4 tablets, 2 in each cheek), let it dissolve, and then swallowed the rest. After 15 minutes, I could feel light cramps. Then, after 30 minutes to an hour, I was having the most painful cramps I’ve ever had in my life. Most pain I’ve ever been through. This excruciating pain lasted for 4 hours until I felt a big gush and thought I’d peed myself, but it was just the first passing of blood and tissue. After it expelled, I instantly felt better. Little to no cramping at all, and I was able to move again. Still bleeding today (day 3). If you are thinking about doing the abortion pill, my advice to you is to know your pain limit. I took 800mg of ibuprofen, and it did absolutely nothing. Ask your doctor for stronger pain relievers because it feels like birth."

10 / 10
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  • tay...
  • January 17, 2021

For Abortion "I’m 18 and got pregnant for the first time. I freaked out and knew right away I couldn't have it. On Day 1, the nurse gave me an antibiotic and then the Mifeprex. With this, I had no symptoms and felt normal. On Day 2, I took the misoprostol orally (4 tablets, 2 in each cheek), let it dissolve, and then swallowed the rest. After 15 minutes, I could feel light cramps. Then, after 30 minutes to an hour, I was having the most painful cramps I’ve ever had in my life. Most pain I’ve ever been through. This excruciating pain lasted for 4 hours until I felt a big gush and thought I’d peed myself, but it was just the first passing of blood and tissue. After it expelled, I instantly felt better. Little to no cramping at all, and I was able to move again. Still bleeding today (day 3). If you are thinking about doing the abortion pill, my advice to you is to know your pain limit. I took 800mg of ibuprofen, and it did absolutely nothing. Ask your doctor for stronger pain relievers because it feels like birth."

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  • tay...
  • January 17, 2021

For Abortion "I’m 18 and got pregnant for the first time. I freaked out and knew right away I couldn't have it. On Day 1, the nurse gave me an antibiotic and then the Mifeprex. With this, I had no symptoms and felt normal. On Day 2, I took the misoprostol orally (4 tablets, 2 in each cheek), let it dissolve, and then swallowed the rest. After 15 minutes, I could feel light cramps. Then, after 30 minutes to an hour, I was having the most painful cramps I’ve ever had in my life. Most pain I’ve ever been through. This excruciating pain lasted for 4 hours until I felt a big gush and thought I’d peed myself, but it was just the first passing of blood and tissue. After it expelled, I instantly felt better. Little to no cramping at all, and I was able to move again. Still bleeding today (day 3). If you are thinking about doing the abortion pill, my advice to you is to know your pain limit. I took 800mg of ibuprofen, and it did absolutely nothing. Ask your doctor for stronger pain relievers because it feels like birth."

10 / 10
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  • Wee...
  • September 6, 2019

For Abortion "I was 6 weeks and 1 day. I definitely worked myself up. The actual experience itself was very easy! I took the first pill at the doctor's office and was given the other pills to take at home. The first pill made me feel nauseous. I was also given antibiotics to take the night before in case of any infection. The next morning, I inserted the first 4 pills into my vagina, the bleeding started 1 hour later. After 2 hours, the bleeding picked up and I passed small clots. I could feel cramping, but it wasn't anything beyond what I'd usually feel during a heavy period. I then passed a massive clot. After that, the bleeding stopped - I called the helpline, and they advised me to insert the remaining 2 pills. I did that, and the bleeding commenced. I then went on to bleed heavily for the following 5 days. I've got a scan scheduled in a couple of weeks, which will make it one month after the medical pills, it's just to make sure there was no tissue left."

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  • JuJ...
  • Taken for less than 1 month
  • April 7, 2020

For Cervical Ripening "I was given misoprostol to widen my cervix for IUD insertion. Swallowed 4 in the morning with food, 3 hours before my IUD insertion. My first IUD wasn’t in properly, so it was removed. They wanted to complete this insertion guided by ultrasound while using this med. Mild cramping at first and no nausea. After the insertion, I cramped quite a bit, but it never reached the discomfort of my typical period cramps. It was odd that they would come in regular intervals, much like contractions, but that happened after my last insertion too. The weirdest thing is that when I’d burp, it tasted really weird. Almost like chemical fertilizer, but luckily the taste didn’t linger. I had a little bit of diarrhea several hours later. I bled a bit, but I was unable to tell if it was cycle-related, related to the IUD, or related to the meds. I didn’t read anything about it beforehand, and I’m glad I didn’t. I would have psyched myself out badly."

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • October 4, 2021

For Cervical Ripening "By far the worst experience of my life. Inserted 4 pills vaginally. About 15 min after, I already felt a little cramping. I thought, OK, I guess this is what happens. Little did I know I was about to go through the most horrific pain ever. As the 'cramping' intensified, I began to feel cold, I was shivering, teeth chattering, and all underneath a blanket. This lasted about over an hour, meanwhile, the cramps were becoming unbearable. I went to the bathroom, had streaming diarrhea, and a while later began projectile vomiting, barely making it to the bathroom in time. The intensity of the cramping was so severe that I cried out for God, hoping this pain would lessen or end. But it didn't. I called the doctor, and they said this happens sometimes and to take the pills out. Unfortunately, I was only able to get two out while urinating. The horrific pain continued as I writhed in agony and torture. 4 days later and still battling severe body aches, weakness, pain on my side, targeted cramping, fevers."

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  • Ano...
  • Taken for less than 1 month
  • April 12, 2021

For Abortion "So I was 5 weeks and 4 days pregnant, and I was so nervous to take this because of a lot of the stories and reviews I read. I also had to keep reminding myself that every person's body is different. But I took the first pill at 4 on a Wednesday, and by Thursday around 3, I was bleeding a little already, and I took my ibuprofen around 3 after eating something. Then I took 4 on Thursday. I took them by mouth, you just insert them in your cheek for 30 mins, and I was nervous I was going to swallow them before, but I didn't, and I washed them down with water after 30 mins. Within 30 mins of doing that, I passed my first clot, and I had a lot of pressure, but nothing crazy. And I didn't have a lot of bleeding. I did have cramps, but the heating pad was my best friend for a few days. I went back for my checkup a week later, and everything went great and worked. Just remember your body is different than the next person. So don't think way too much into it."

10 / 10
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  • Ash...
  • Taken for less than 1 month
  • November 16, 2019

For Abortion "I took a Gravol at 10 am, then at 11 am I took the first pill. Felt nothing, no nausea or anything. The following day I took Gravol at about 5 pm. I put the 4 pills in my cheeks at 6 pm, kept them in till 6:30 pm and swallowed. Shortly after, I had very mild cramps, no blood. At 9 pm, I started to bleed with heavier cramping (but tolerable). 20 minutes later, I had a serious urge to go to the loo. Went to the bathroom and out stuff came. Minutes later, the cramping started to chill out. I was so scared after reading the reviews, but it was seriously minor for me."

10 / 10
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  • Mee...
  • Taken for less than 1 month
  • April 19, 2021

For Cervical Ripening "Took misoprostol before an IUD insertion to soften my cervix since the first try didn't work. Was told that all my doctor's other patients had some nausea at worst, and most felt nothing. I was instructed to take it buccally (dissolved in my cheek) a few hours before the procedure. I was in a college class at the time and had to run out to the restroom within 5 to 10 minutes of taking it. At first, I was dizzy, then got every symptom on the bottle to the worst extreme. Nausea, vomiting, diarrhea, and the absolute WORST cramps of my entire life. I literally writhed on the bathroom floor at college. This was literally the most painful experience of my entire life, to the point where they listed it on my file as an allergy. I got my IUD inserted successfully afterwards and have had it for almost 5 years now."

2 / 10
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  • Nic...
  • Taken for less than 1 month
  • February 9, 2020

For Labor Induction "I took the pill 2/8/2020. I was 8 weeks pregnant, and the doctor didn’t find a heartbeat, so they confirmed my baby wasn't alive. They sent this pill to the pharmacy, so I read the reviews before I took the pill, and it made me so nervous. I kept pushing back to take it because the reviews made me think it’s a horrible pain you're going to feel (negative for me). They said it’s labor pains. DO NOT READ THE REVIEWS - JUST DO IT. Because once I took them, the pain was MINOR CRAMPS. I slept through it all. When I woke up, it was period cramps, that’s it. I had nothing to make you feel like you need heavy drugs. Remember, everyone is different. Once I took it, just fall asleep, you’ll be okay. The cramps lasted 20 minutes, the bleeding is still here, but no uncomfortable pain or anything. If you have to take this pill, you got this. Stay strong. I didn’t take any drugs, they prescribed me Vicodin, and I didn’t even need that medicine. When I woke up, I drank plenty of water and watched TV."

10 / 10
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  • Dar...
  • Taken for less than 1 month
  • July 10, 2019

For Abortion "I just wanted to write a review from my good experience because I worked myself up silly after reading awful reviews on here as I have a huge phobia of sickness, etc. The first tablet did make me sick, but this tablet was great. I did get cramps, and yes, they are more painful than periods, but that was about it. You will pass pretty big clots and bleed heavily, so stock up on extra thick pads, but from my experience, I am very happy. Don't believe everything you read on the internet, some of it is the placebo effect from working yourself up. Insert vaginally if you want. TRY and avoid the side effects (not saying it will eliminate as everyone is different), but yeah, the bad pains for me didn't last more than 5 hours. It's not pleasant (obviously), but not godawful either. Good luck!"

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  • Ale...
  • Taken for less than 1 month
  • November 19, 2019

For Abortion "Took 800 mg ibuprofen and Tylenol & Promethazine. Waited an hour, then I took the 4 Misoprostol pills buccally at around 2:00 am. 30 minutes later, I started bleeding, no cramps. An hour later, I started passing clots and almost no cramps. Fell asleep at around 4:30 am, didn’t wake up until 10 am when I got up, everything came out. Then had bleeding like a regular period and mild cramping all day. Was surprised I didn’t feel any pain, I had read reviews before taking them and was TERRIFIED. Now I just need to go to my follow-up and make sure I passed everything."

9 / 10
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  • Jum...
  • Taken for less than 1 month
  • November 17, 2019

For Abortion "I’m 7 weeks pregnant, and I started the second dose at home on Saturday at 12. I immediately started feeling cramps within that hour, and the cramps started heavily kicking in, but it felt like my normal period cramps, but 10x worse. I was given ibuprofen 800 mg every 4 hrs. The pain lasted 'til after midnight. I honestly thought it was supposed to past 4-6 hrs, so I was watching movies to pass time. It was painful but bearable. I bled the first 4-5 hrs, but I didn’t see any tissue come through, it felt like my normal heavy period. I’m honestly a little scared I might have to take it again, but the overall experience was painful but bearable. But like the doctor told me, every woman’s body is different. Just make sure you take pain meds and get rest... watch movies to keep your mind off of it. Go to the follow-up appointments. I didn’t get any of the other symptoms of vomiting or diarrhea. I hope this helps."

8 / 10
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  • Man...
  • Taken for less than 1 month
  • December 31, 2020

For Abortion "I took 1 pill at the clinic, 4 pills the next day. The pain started within seconds once I swallowed the medicine. Worst cramps ever! I did take ibuprofen and anti-nausea medication. But I still suffered pain. I wasn’t able to sleep because the pain was so bad. 8 hours later, blood clots are still coming out, and I’m still getting cramps, but they aren’t as bad as they were in the very beginning. My opinion: if you do not have a good tolerance for pain, do not take these. I was very sad due to the circumstances, but I’m glad I’m almost over this pain already. Good luck, ladies."

10 / 10
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  • Ano...
  • Taken for less than 1 month
  • October 3, 2020

For Abortion "I took the normal single dose of misoprostol at the clinic. The next evening, I put the 4 pills in my cheeks. Roughly 15 minutes in, I had painful cramping. It was like severe period cramps, at first constant, then in waves of every few minutes or so over 45 minutes to an hour. Sitting on the toilet helped, and I had some initial bleeding. After, the cramps ceased for roughly 45 minutes. Then I had major cramping beginning in my stomach similar to gas pains. What happened next was the absolute most insane and explosive diarrhea I have ever had. Shocked that the toilet didn’t split in two. During the episode, I got chills and nearly lost my breath. If you feel gas pains, just sit in the bathroom or you WILL NOT make it to the toilet. I had major bleeding during this, but after, no more diarrhea and mild cramps continued into the night."

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  • Ano...
  • Taken for less than 1 month
  • February 21, 2025

For Abortion "I read a lot of the reviews on here… and they made me very nervous to take these pills… so I thought I’d jump on and tell my experience. I was about 6 weeks pregnant. Took the first pill as directed… no side effects from the first pill. Took the second step (4 pills in cheeks of mouth for 30 mins) 24 hours after. 30 minutes went by and started to cramp mildly, not painful at all. Another 30 minutes went and started to bleed a bit with still mild cramping. I did experience the chills and felt nauseous at this point. I laid down with mild cramping, bleeding, and chills. At about the 2nd hour into things, I passed a clot about the size of a grape. I felt instant relief. After, I did experience diarrhea and mild cramping for the next 6 hours, but the next day I felt completely better with mild bleeding like a period. I’m hoping this review will help others, as the pain was very temporary! You got this!!"

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  • Www...
  • Taken for less than 1 month
  • January 21, 2021

For Abortion "I had a miscarriage at about 9 weeks pregnant, but the fetus was about 7w5. This was a wanted pregnancy. I had a surgical abortion in the past and passed out because of the sedation and had nausea, so I decided to go with the medical abortion this time. The doctor inserted 4 pills at 9 am. I started bleeding around 12:30 pm. I had very mild cramps (like period cramps) between 12:30 and 5:30. At 5:30, I had one big cramp, and I knew the fetus was going to come out. I walked to the toilet and felt a 'bloup', I saw my fetus. After, I had mild cramps for 30 minutes. I stayed over the toilet and clots came out. I was bleeding for an hour, and then it started to be like period bleeding with still some little cramps but nothing painful. Overall, I had a very good experience, I was relaxing at home, and it took 30 minutes to get everything out with not a lot of pain. The next morning, I was feeling very good."

10 / 10
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  • Feb...
  • Taken for less than 1 month
  • February 20, 2022

For Abortion "I was around 4-5 weeks pregnant. I was prepared for the worst, but it was not that bad. I was instructed to take all 4 tablets vaginally. Cramping began within 15 minutes, but I didn’t start bleeding for about 5 hours. The pain was about a 5/10 in my opinion. I took the pain reliever dosage I was prescribed, but I did not take the Gravol I was given. I only needed two rounds of pain relievers overall. The real lifesaver was my heating pad. Bleeding was heavy, about twice as heavy as my period on its worst day (I used an overnight maxi pad for the first time in my life). But it subsided the next morning, and currently, I am on day two, and only very light bleeding at this point. I am so relieved this is done with and glad I did the medical route rather than surgery. Just be prepared with any supplies you need (pain relievers, heating pad, maxi pads) and a good TV show, and you will be okay."

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