Pentasa and Nausea: What Users Say

• Anonymous
• September 29, 2011

For Ulcerative Colitis, Active "I took Pentasa for ulcerative colitis after Asacol started failing. Asacol had worked for me for seven years, but when P&G started having manufacturers make it in Europe, it no longer worked. The Pentasa worked for my ulcerative colitis at a 3-gram per day dosage. The side effects are much worse for Pentasa. I experienced nausea, mild headaches, and severe hair loss."

• red...
• December 26, 2009

For Crohn's Disease, Maintenance "My husband has only been taking Pentasa for a few days, but he has had terrible side effects since day one. His Crohn's had become progressively worse over the years, so his GI doctor prescribed Pentasa. He has chest pains, headaches, severe nausea and vomiting, as well as loss of appetite. I saw that one person had to lower his dose after 3 weeks, and I wonder if that was due to his experience of these effects also. I know Pentasa has great potential, but how long will these effects last?"

• Gig...
• February 25, 2010

For Crohn's Disease, Maintenance "I was diagnosed with Crohn's in 2005 after having years of severe diarrhea, stomach pain/cramping, and nausea. After a few weeks of taking the Pentasa (4 grams daily), I felt unbelievably better. Within the last year, I have had lots of breakthrough flares and have had to add other meds (6-MP and Humira shots). I have had an active flare since mid-December with no relief. I have reduced my Pentasa to 2 grams a day because I had noticed that my nausea and other symptoms were more severe on the 4 grams. Even though I feel better, my symptoms have not improved enough, and I have to now add Remicade infusion therapy to my long list of meds. I think that these meds are helpful as long as they are adjusted depending on your symptoms."