Mercaptopurine and Tiredness: What Users Say

• Jo2...
• February 17, 2017

For Crohn's Disease, Maintenance "This medicine will make you feel like you've been hit by a car every day, exhausted, plus your liver and pancreas take a massive hit. I had constant pain and all my Crohn's complaints returned. I was fine on prednisone and Entocort, but my doctor wanted to make it even better. Please pay EXTREME CAUTION using this medicine before ending up in the hospital. I'm not saying this medicine is bad, but for one person, it seems extremely well or extremely bad, in my case, the worst time I've ever been through. Pay attention!"

• Jnd...
• Taken for 1 to 6 months
• October 29, 2016

For Crohn's Disease, Maintenance "I've been using this drug for just over a month, and everything seems like it's going downhill. This drug will make me extremely tired but also keep me awake. It's too inconsistent for my body. It should be helping with bodily functions and minimizing pain, but it does quite the opposite. Some days my body can't move very fast because of the pain. And if it's not the pain, it's fatigue all day. I've had the same problem with other drugs like this. There has to be a way to help without all of the drugs or surgeries."

• mic...
• Taken for less than 1 month
• January 19, 2013

For Crohn's Disease, Maintenance "I have been on this medicine for a week. I have no energy, and I only sleep about 4 hours a night. I can fall asleep but can't stay asleep. I think I am going to ask my doctor to switch me to something else. I can't focus very well with this medicine."

• max...
• Taken for 1 to 6 months
• June 10, 2025

For Ulcerative Colitis, Maintenance "Tired all the time, can't sleep at night and sleep during the day. Works well besides that."