Mercaptopurine and Fatigue: What Users Say

• Anonymous
• October 4, 2011

For Ulcerative Colitis, Maintenance "I tried it for two days and was so sick I could not function. Symptoms included severe dizziness, feeling of faintness, fatigue, unfocused, could not see straight, bloated upset stomach, diarrhea. Now they want me to try a lower dose and see if I get used to it."

• tin...
• August 6, 2017

For Crohn's Disease, Maintenance "This drug is a nightmare!!! Total fatigue with breathlessness, arm weakness and numbness, nausea, light-headedness. Now have developed tinnitus, which is a constant pulsation through ears and head. My white blood cells have dropped dangerously low, and my red blood cells are really poor. I am naturally now off the drug but don't know how long till I get back to health. ONLY GO ON THIS DRUG AS A LAST RESORT>"

• Jnd...
• Taken for 1 to 6 months
• October 29, 2016

For Crohn's Disease, Maintenance "I've been using this drug for just over a month, and everything seems like it's going downhill. This drug will make me extremely tired but also keep me awake. It's too inconsistent for my body. It should be helping with bodily functions and minimizing pain, but it does quite the opposite. Some days my body can't move very fast because of the pain. And if it's not the pain, it's fatigue all day. I've had the same problem with other drugs like this. There has to be a way to help without all of the drugs or surgeries."

• Anonymous
• July 21, 2011

For Crohn's Disease, Active "This medication was very effective for all my Crohn's symptoms (including lack of energy, nausea, bleeding, etc.). It is like night vs. day being on this medication and being off of it."

• Ber...
• Taken for 1 to 2 years
• March 15, 2020

For Crohn's Disease, Maintenance "I have side effects of fatigue, so now I take the pill at 8-9 pm. I do feel the side effects while I am asleep."