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Mercaptopurine and Nausea: What Users Say

Brand names: Purixan, Purinethol

Nausea: mentioned by 4 users (12.9%)

Based on user experiences from 31 Mercaptopurine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

fatigue 16.1%
nausea 12.9%
pain 9.7%
tiredness 9.7%
vomiting 9.7%

Reviews for Mercaptopurine

Commonly mentioned side effects
  • tin...
  • August 6, 2017

For Crohn's Disease, Maintenance "This drug is a nightmare!!! Total fatigue with breathlessness, arm weakness and numbness, nausea, light-headedness. Now have developed tinnitus, which is a constant pulsation through ears and head. My white blood cells have dropped dangerously low, and my red blood cells are really poor. I am naturally now off the drug but don't know how long till I get back to health. ONLY GO ON THIS DRUG AS A LAST RESORT>"

1 / 10
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15 Report
  • Amy...
  • Taken for 10 years or more
  • July 24, 2020

For Ulcerative Colitis, Maintenance "Started 6MP (mercaptopurine) after spending almost 2 years on prednisone for my chronic ulcerative colitis. The first year was the toughest, chronic nausea, but so worth it in the end. Been healthy and in remission for 14 years. Unfortunately, was taking 75 mg, but it’s now showing that my liver isn’t properly metabolizing the drug even though my liver enzymes are normal!!! It’s unreal that now I’m taking 50 mg and showing signs of slowly working toward a flare-up. Chronic belly pain. I would stay on this forever if I can. Petrified to try anything else. Would recommend this drug to anyone with moderate to severe UC!! I also have pancolitis, so that means my entire colon is bad. And this drug works!!"

10 / 10
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5 Report
  • Anonymous
  • Taken for less than 1 month
  • November 21, 2021

For Crohn's Disease, Maintenance "I'm using this medicine for 3 days now, and since 2 nights, I haven't been able to sleep properly. And I also have nausea till 11 a.m. the next day because I take my medication at dinner time. For now, this is my last resort before they put me on biomedicine. I hope I feel better and less tired soon."

3 / 10
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4 Report
  • Anonymous
  • July 21, 2011

For Crohn's Disease, Active "This medication was very effective for all my Crohn's symptoms (including lack of energy, nausea, bleeding, etc.). It is like night vs. day being on this medication and being off of it."

10 / 10
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18 Report

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