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Medroxyprogesterone and Acne: What Users Say (Page 2)

Brand names: Provera, Depo Provera, depo-subQ provera 104

Reviews for Medroxyprogesterone

Commonly mentioned side effects
  • Sar...
  • May 7, 2015

Medroxyprogesterone for Birth Control "Honestly, everyone's bodies work differently, and I've heard horror stories about every type of birth control, but this one has been really excellent for me. I've been on the Depo shot for 5 years now (planning on switching soon). The shot does sting a bit, so be sure it's injected into your hip instead of your arm. The first month I spotted nonstop, but I haven't had a single period since. No pregnancy scares. Very gradual weight gain for me, 25 lbs over the past five years. Cleared up my acne, have plenty of libido. I give it 10/10."

10 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • June 24, 2022

Medroxyprogesterone for Birth Control "The absolute worst thing I have EVER tried in my life. It has made my life a living hell for the past 6.5 months, and I still live in hell. I have gotten 2 shots of Depo and refused to go for the 3rd shot, which was due a little over 2 weeks ago. I have gained 20 lbs so far, and it’s gotten even worse since I stopped the shot 2 weeks ago. Depression, acne, and mood swings are horrible, but the worst of all was the constant heavy bleeding for 5 months EVERY SINGLE DAY! I became severely anemic that I could barely walk for 10 minutes due to extreme fatigue and exhaustion. No sex drive and no desire to do anything at all! Just sleeping half of the day and feeling tired without doing anything. This shot has been the worst nightmare for me. I wish I had done my research before getting it. I now regret it 200%."

1 / 10
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  • Wor...
  • November 8, 2015

Medroxyprogesterone for Abnormal Uterine Bleeding "Depo stopped my period when I got my first shot. Almost a week later, I started spotting. I had been consistently spotting for about three weeks. Then I just started bleeding more. It wasn't bad, but it's progressively gotten heavier with large clots. Been over 8 days now. I've had headaches, acne, increased appetite, no sex drive, painful sex, fatigue, chills, abnormal bleeding. Worst decision I've ever made."

1 / 10
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Frequently asked questions

  • Lis...
  • July 10, 2019

Medroxyprogesterone for Birth Control "The Depo shot has ruined my life! I took the shot one time in February 2019. I was in school but had to drop classes because the side effects were so horrible! I suffered extreme anxiety and depression to the point of really dark thoughts. Before the shot, I would cry for my boyfriend because I missed him, and since the shot, I have doubted if I love him and feel indifferent. I was also very close to my family and had a very deep, tender love for them, and I also feel indifferent with them. I had very violent thoughts, a little paranoia, and weird dreams. I became physically ill due to the anxiety and loss of appetite. I lost 7 pounds in 3 days. It caused nasty back acne. I did not get another shot when I was due in May 2019, and it's been two months since I was due for the next shot, and I am still struggling. I don’t feel like myself, I feel like a ghost, and I just exist. I believe I am still suffering from depression."

1 / 10
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  • Amy...
  • Taken for less than 1 month
  • March 12, 2018

Medroxyprogesterone for Abnormal Uterine Bleeding "OMG! I was freaking out because after the 10 days of Provera 10 mg I took, I thought I would be okay, but after 2 days of taking the 10-day treatment, my period is like running water. Even when I was in my heavy days, I would never wake up to a stained bed, and this morning it was soaking. I don't have many clots, and the ones I have are small, but my period lasts for 7 days, and today is my 6th day and still going heavy. I hope it goes away by the 7th day. For sure, I'm going to stop taking any vitamins and any pills I take that could probably make my period even more heavy, just until this period goes away. Oh, it has many side effects, mine were pimples, headache, sleepiness, spotting, and shortness of breath. I really hope after this period my next ones are light, after all, it's like a period cleanser."

5 / 10
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  • HOP...
  • Taken for 5 to 10 years
  • June 2, 2017

Medroxyprogesterone for Abnormal Uterine Bleeding "My experience with this medication started when I was 14 years old. I knew nothing about this medication, and I wish someone would have sat down and told me what exactly this medication does! I decided for the third time to try to get off this medication, I finally decided this time it was enough, so my last shot was October 2016. The beginning was great, I was happy-go-lucky, outgoing, had my life back after having a breast reduction. No period, no cramps, gained a few pounds, but it was worth it at the time for freedom. Now, at 23, I've been in the hospital and given three pills at once. I've soaked through over 10 pads a day and blood clots after blood clots: depression, weight gain, acne, severe cramps, dizziness, tiredness, and withdrawals from this medication."

3 / 10
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  • TLC...
  • Taken for 2 to 5 years
  • February 26, 2020

Medroxyprogesterone for Birth Control "I started out using this medication for birth control reasons. I never had an issue with acne or anything like that before or after starting this medication. I didn’t notice excess weight gain or any of the so-called 'common' side effects. The only thing that happened was I stopped having my period completely after a month or so. And I was okay with that since I’ve always had painful menstrual cycles. I was on this medication for 5 years but was told that I had to change birth control methods due to bone density issues that others have had. I cannot wait to get back on it when I can."

10 / 10
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  • Cyn...
  • Taken for 5 to 10 years
  • June 2, 2016

Medroxyprogesterone for Birth Control "I started taking the Depo shot in 2012 after my son was born. I absolutely have no problems up to date. Within the first shot, I stopped getting periods. I spot a teeny tiny bit when it's close to getting the shot again. But such as hair loss, weight gain, and acne, and all the other side effects, I have none. I'm satisfied with the shot."

10 / 10
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  • idk...
  • Taken for 1 to 6 months
  • July 21, 2021

Medroxyprogesterone for Birth Control "I was on Depo Provera for 6 months. Prior to taking it, I was 130 pounds with a flat stomach and DDDs. I am a power lifter who exercises at least 3-4 times a week for about 2 1/2 hours. I am now 175 pounds with H cup breasts, covered in acne in places I’ve never had it before, exponentially more tired and depressed, constantly nauseous, the gastrointestinal issues I had prior were made 100 times worse, and now that I just passed the date I was supposed to get my 3rd injection, I’m on day 31 of my period. I was never warned about any of this except 'you may gain about 3 pounds in a year of taking this!' I’ve been on two other brands of birth control pills and never have I experienced this or anything similar. The Depo injection has ruined my body and my mental health. If I could negatively rate, I would."

1 / 10
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  • Sad...
  • Taken for 1 to 6 months
  • September 7, 2015

Medroxyprogesterone for Abnormal Uterine Bleeding "My doctor recommended this shot to me to help with cramps due to having endometriosis. I have received 2 shots and have been on my period for a total of 5 months now! The shot helped with pain the first 3 months, and now it doesn't help at all. I will not be going back for another shot. It is awful! I've gained weight, I'm moody, and fatigued. And in case you missed it the first time, I've been bleeding for 5 months! Just think of the pads, tampons, laundry, ibuprofen, chocolate, ice cream, occasional apologies to your boyfriend, and acne you'll get to look forward to... just say no to this joke of a drug!"

1 / 10
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  • MsT...
  • December 5, 2014

Medroxyprogesterone for Birth Control "I've been on the shot for 7 years, no cycle, no other children, and no weight gain. The only side effect that I think I'm having now is a low sex drive because I can't get into sex like I used to. I don't like taking pills and forget to with vitamins, so I know they wouldn't be a good idea. But I do think being on the shot for so long actually messed with the hormones because my face tends to break out every other week, but other than that I love it, but it's time to get off!"

9 / 10
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  • Dev...
  • September 20, 2016

Medroxyprogesterone for Birth Control "I am writing this review because most people don't bother writing reviews when they have a positive experience, and it can sway others not to use Depo when many women don't have issues. I have been on Depo consistently for 5 years now, with zero complaints. In the first year, I had irregular periods and stopped having them completely after that. I get about one period per year now, if that. I did not get any acne, but I've never had acne problems anyway. I do believe Depo causes weight gain, although it could just be because I started taking it at 18 years old (about 120 lbs) and now I'm 23 (145 lbs). I can't say for sure if it's the Depo, but I have to work out just to stay the same. All around though, I would recommend Depo 100%!"

10 / 10
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  • sun...
  • Taken for 1 to 6 months
  • September 17, 2015

Medroxyprogesterone for Abnormal Uterine Bleeding "I got the shot last month to help with my endometriosis, I was on my period at the time. After my period stopped, everything was fine, but once I got my period, things started to go downhill *not by much*. I started my period, and it wasn't so heavy at first, and my pain was gone, but now I'm stuck on my period. I have been bleeding for over two weeks now, and cramps come and go. My face broke out and hasn't stopped, which is weird for me because it doesn't ever last this long. I'm really starting to think it's not worth it if I'm still on my period all the time because now I feel like I can't do much, like swimming or being crazy active, because I feel weak and just drained."

3 / 10
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  • Lou...
  • November 6, 2018

Medroxyprogesterone for Birth Control "I recommend no one ever tries this. I had my first injection and felt fine for 3 months (at least I thought I did). After my second injection, I felt completely different. Since having my second injection, I don’t feel like the same person. I have had 4 panic attacks and am suffering with bad anxiety. I am constantly worrying about my health and diagnosing myself with all sorts of side effects of the injection. I feel like a severe hypochondriac at the moment. Not only has it messed with my mental health, making me constantly worried, anxious, and stressed, it has caused me to get cystic acne. 2 weeks into my second injection, I saw 3 spots appear on my face (I’ve never had spots in my life). How wrong was that, causing them to get bigger and painful? The more the injection wears off, the smaller they seem to get. I have not yet been to my GP about my problem yet, as I want to let it wear out of my body and pray I get back to my normal self and my skin gets better - do not get it."

1 / 10
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  • mar...
  • March 2, 2016

Medroxyprogesterone for Birth Control "If I wanted to be covered in acne, moody, and in pain, I would have just gone out and gotten pregnant! Several days after receiving the shot, I had strong-smelling, dark brown discharge for about a week, which was followed by 4 LONG MONTHS OF CONTINUAL BLEEDING. Haven't been able to test out its effectiveness because I haven't been able to stop discharging/bleeding, which defeats the purpose of this shot. Although this seems like a great option, these shots last for 3 months, so if you react to it like me, you'll be stuck until it flushes out of your system. Got the shot back in September, and my periods are still not back to normal."

1 / 10
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  • SWa...
  • Taken for less than 1 month
  • August 13, 2019

For Amenorrhea "After three months with no period, my doctor chose to put me on one pill a day for 10 days. (All bloodwork and an ultrasound were normal.) During the use of this medication, I experienced mood swings, irritability, cystic acne, and vaginal discharge. Five days after finishing the medicine, I started my period. It was heavy. My doctor warned me of the side effects and heavy period. However, it gave me a period, which is what I hoped for and is important to prevent uterine cancers. I recommend this medicine. But be aware of side effects. Ride them out, and hopefully you’ll get your period. I am 38, married, but have never been pregnant."

10 / 10
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  • Ste...
  • Taken for 1 to 6 months
  • June 22, 2013

Medroxyprogesterone for Birth Control "I've been on the Depo-Provera shot for about 6 months now, and I was absolutely terrified of gaining weight on it because of the multiple stories I've heard. But I actually lost weight, so I love it. I haven't noticed any change in mood. Perhaps a slight increase in acne, but hardly anything to complain about. I did have spotting for about 3 weeks in the beginning. Overall, I really like it. I don't have to take a pill every day, and there aren't really any noticeable side effects."

9 / 10
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  • Cha...
  • September 13, 2015

Medroxyprogesterone for Abnormal Uterine Bleeding "I absolutely hate this. I have been on Depo for 6 months, and I have bled the whole time. Nonstop. No breaks. It's not light either. It's like being on the second day of your period forever. It has also significantly worsened my depression. I had finally gotten a combo of meds and therapy that had me feeling relatively functional. I made the mistake of taking Depo. It ruined all my progress and has me debating suicide again. I've gained weight and developed acne. This sucks, don't ever take it. They'll tell you it can stop your periods. Don't be deceived!"

1 / 10
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  • Don...
  • April 25, 2017

Medroxyprogesterone for Birth Control "I wish I would've listened to the reviews before getting this shot. It has caused me to have severe anxiety and panic attacks. I can only hope that I'm able to go back to normal after these hormones are out of my system. Additionally, my acne has worsened, and I'm hungry all the time. But none of that compares to the anxiety. I haven't felt like myself in weeks. Absolutely do not try this shot if you are able to get another method of birth control."

2 / 10
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  • Kle...
  • February 23, 2017

Medroxyprogesterone for Birth Control "Everyone is different! However, I do not suggest this medicine if it can be avoided. Due to an abnormality in my blood, my only BC option was the Depo shot. I have been miserable since day one, and it's not getting any better. I read all the reviews against it, but I was set that it would be different for me. Hard no! My acne tripled in severity. I experience shortness of breath and muscle fatigue on the daily. The mood swings have been out of control, and ultimately I no longer feel like myself. This has really impacted my life, and I strongly urge you to avoid."

1 / 10
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  • Mrs...
  • Taken for 2 to 5 years
  • January 9, 2020

Medroxyprogesterone for Abnormal Uterine Bleeding "I have been off Depo for 9 months, it did what it was supposed to, and I didn't get pregnant while on it, nor did I have a single period after the 2nd month. However, now that I am off the shot and trying to get pregnant, I am having a hard time. We have been trying for 4 months, and I am having irregular bleeding between periods, missing periods, even 2 in one month after I missed one, and am not even sure I am ovulating because we try almost every day... Not only that, but I still have cystic acne from it! My skin has not looked this bad since middle school. I do NOT recommend this stuff!"

2 / 10
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  • Coc...
  • September 1, 2013

Medroxyprogesterone for Birth Control "Depo-Provera worked very well. In fact, I really loved it. I only gained about 3 pounds (I do work out 4/5 times a week). Had my period 3 times a year, and it was so easy, just one shot every three months. The only downside was I got a bunch of acne and a bit of hair loss. Each month around my period, I still had the cravings but never got my period! Now that I am off, my acne cleared up a bit. I highly recommend this birth control! Very effective!"

9 / 10
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  • Cas...
  • Taken for 1 to 6 months
  • September 17, 2019

Medroxyprogesterone for Abnormal Uterine Bleeding "I got the shot in mid-June. On July 18th, I started getting the signs of a period. I went through all the symptoms for a week with no bleeding. I finally started bleeding, but it was dark brown and tar-like. It's September 18th, and with only a week break, I have been bleeding this whole time. My skin is breaking out horribly (never used to break out). Can't lose weight, increased appetite, period symptoms the whole entire time (moodiness, lethargic, etc.). No sex drive. Like 100% non-existent. Cannot tell people enough: DO NOT GET THIS SHOT."

1 / 10
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  • tir...
  • Taken for 5 to 10 years
  • May 24, 2015

Medroxyprogesterone for Abnormal Uterine Bleeding "I was on Depo from the ages of 17-21 with absolutely NO problems, NO bleeding, it stopped my periods completely, NO side effects. I went back on the Depo August 2013 (currently ages 25-27) and have been getting the shots every 3 months on the first date they are due. I have been spotting/bleeding almost the whole time. When I have sex, it seems to make me bleed more. Everything has been ruled out, and it's just been blamed as a side effect of the Depo from my doctor. I also managed to get pregnant and have a miscarriage while on the shot/on time with each due date. The longer I am on this, the more side effects I am starting to get (acne, SEVERE depression, anxiety, and mood swings). I recommend for younger only."

3 / 10
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  • Man...
  • February 27, 2013

Medroxyprogesterone for Birth Control "I've been on the Depo for about 4 months now. I got on it to stop my period, but I've had nonstop bleeding the whole time! I asked my doctor if there was anything she could do, and she said to wait it out. I searched about bleeding on the shot, and tons of people said they bleed continuously the whole time they were on, and some said once they stopped the shot, the bleeding didn't stop. I also am breaking out in places I normally don't, like in my neck line and forehead. I'm not getting the shot again if the bleeding doesn't stop."

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.