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Cytomel and Muscle Pain: What Users Say

Muscle pain: mentioned by 4 users (7.7%)

Based on user experiences from 52 Cytomel reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

heart palpitations 17.3%
anxiety 15.4%
depression 11.5%
hair loss 11.5%
fatigue 9.6%
weight gain 9.6%
brain fog 7.7%
insomnia 7.7%
muscle pain 7.7%
sweating 7.7%

Reviews for Cytomel

  • Sam...
  • Taken for 1 to 2 years
  • June 16, 2019

For Hypothyroidism, After Thyroid Removal "Cytomel is causing debilitating symptoms such as severe muscle cramps/spasms and muscle pain, insomnia, ravenous appetite, profuse sweating, and palpitations. When I stopped taking it, I got better. I tried to reintroduce it, and to my horror, the severe spasms returned. The prescribed muscle relaxers hardly work. The endocrinologist said my symptoms are not related to the prescribed medication or to my thyroid condition! I disagree. I've had problems with Armour in the distant past. For some reason, I can't take Cytomel or Armour long term."

2 / 10
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44 Report
  • Jou...
  • May 4, 2022

For Underactive Thyroid "Was on generic liothyronine for about 5 weeks because Cytomel wasn’t available. Felt like a windup toy whose spring had unwound-horrible muscle pain, weakness, couldn’t think, and constant background pain. Today, finally got my Rx of Cytomel. The difference is remarkable. Within 1 hr, my muscles started relaxing. Three hours later, and my mental acuity is back. There truly is a difference between generic and brand name. I would never have known that were it not for my shrewd doctor. This is like a miracle drug that restores my life. I take 5 MCG, 2x daily Cytomel and 50 MCG 1x daily of Synthroid."

10 / 10
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15 Report
  • Luc...
  • Taken for less than 1 month
  • July 22, 2022

For Underactive Thyroid "I have Hashimoto's disease and hypothyroidism with it. I was on Tirosint for a while and all the other T4 medications: Levothyroxine, Synthroid, Tirosint. This Cytomel makes me feel amazing and turns my brain back on immediately after taking it. Cytomel also seems to get rid of almost all the horrible joint pain and muscle aches from the other thyroid medications. It also helps to reduce my muscle stiffness and gets rid of those pesky muscle spasms. I think that all the T4 drugs actually cause more pain all over the body, but they are usually effective at getting rid of hypothyroid symptoms. I noticed this after I forgot to take my Synthroid for one day, less pain but more fatigue."

10 / 10
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13 Report

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Frequently asked questions

  • Jou...
  • Taken for 5 to 10 years
  • April 23, 2022

For Underactive Thyroid "Taking Synthroid for Hashimoto’s and continued to have fatigue, muscle aches, and cramps. Adding Doctor generic Liothyronine was like taking nothing. Switching to brand name Cytomel 5 mcg 2x daily, I felt normal for the first time in 10 years. Muscle aches/cramping gone, good energy and mental focus returned. I have my heart under control, and I’m still on Cytomel. Hair loss I've also had, and you need to have your selenium levels tested. I had some doctor-prescribed supplements I had to stop because they contained selenium and it built up. Right now the biggest problem is that I can’t get my Cytomel Rx filled because Pfizer has some backorder that’s gone on for two months with no explanation. I have to take generic liothyronine for now; fatigue and muscle cramps are back."

10 / 10
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11 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.