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Cytomel and Anxiety: What Users Say

Anxiety: mentioned by 8 users (15.4%)

Based on user experiences from 52 Cytomel reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

heart palpitations 17.3%
anxiety 15.4%
depression 11.5%
hair loss 11.5%
fatigue 9.6%
weight gain 9.6%
brain fog 7.7%
insomnia 7.7%
muscle pain 7.7%
sweating 7.7%

Reviews for Cytomel

Commonly mentioned side effects
  • Lit...
  • May 28, 2017

For Underactive Thyroid "Cytomel is making my brain work so much better again! I tried it several years ago and it made me jittery, I felt like I had a huge amount of caffeine in me... not this time! I'm in perimenopause and I understand the estrogen dominance can be a thyroid hormone antagonist, making it difficult to convert. Cytomel has helped me feel almost entirely back to normal and I have the energy to exercise again!"

10 / 10
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183 Report
  • Tin...
  • Taken for 1 to 6 months
  • June 10, 2019

For Hypothyroidism, After Thyroid Removal "An endocrinologist put me on the 50 mg per day post TT. I felt tremendous. Then my insurance changed, and I had to find a new doctor. The new doctor refused to prescribe Cytomel. So for several years, I’ve been on Synthroid 200 and 300, and then Nature-Throid 3 grains. The Nature-Throid won out over the Synthroid by far. But my total T3 and FT3 were still tanked. I began seeing a functional medicine doctor who suggested T3-only medication. WHAT A LIFE CHANGER! I take 25 mg per day. Gone is the anxiety, mood swings, depression, weight gain, brain fog, and insomnia. I feel like a brand new person at 62. My doctor follows my labs closely, and all thyroid levels are in range (FT3 upper range, FT4 mid-range). I highly recommend trying this monotherapy if you don’t have a thyroid gland and other medication regimens have failed."

10 / 10
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140 Report
  • Cou...
  • Taken for 6 months to 1 year
  • January 18, 2020

For Underactive Thyroid "Hashimoto's patient. Take 88 mcg of Synthroid and took 5 mcg of Cytomel for almost a year. Felt better at first and then felt completely insane. Mood swings, anxiety, depression, rage, tachycardia, and hand tremors. Sketchy stuff that. If you feel crazy, cut the Cytomel before you get on or up your antidepressants."

3 / 10
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103 Report

Frequently asked questions

  • jil...
  • February 25, 2015

For Underactive Thyroid "After being hypothyroid for many years and having good results on Synthroid and natural thyroid, it went on backorder for a few months and I had to switch to Cytomel. I felt immediate changes, more alert and a little more energy. However, after taking it for a few years, about 70% of my hair fell out (in clumps and I tried everything to stop the hair loss), and I've had chronic insomnia, huge appetite increase, higher blood pressure, anxiety attacks, hot flashes, etc."

2 / 10
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146 Report
  • Ale...
  • Taken for 6 months to 1 year
  • April 3, 2019

For Underactive Thyroid "My doctor recommended this since my symptoms weren't going away on levothyroxine alone. Worst year of my life. Mood swings and crippling anxiety. This drug made me completely irrational, and the anxiety got so bad that daily activities, like driving my car, would make my heart race and hands shake. Wish I could get that year of my life back."

1 / 10
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76 Report

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  • KS5...
  • August 17, 2018

For Underactive Thyroid "Glad this med has helped some, but for me, it was a four-year nightmare. The anxiety was horrendous, as in disabling. Sweating, temper was on a hair trigger, hot flushing on my back (TSH around 0). I even went into the hospital for two days to have my heart checked out, which was fine. I started noticing I would feel more normal each time the med dose was missed. I started coming down by 1/4 pill at a time, and each time it helped. Finally, I came down to 1/4 pill in addition to my 88 mcg Levo. I was exhausted by 11 am, and my TSH was 6, but at least I wasn't peeling myself off the ceiling, and I was calm. I finally went off it entirely, and the anxiety, although not completely gone, was vastly improved. I upped my Levo to 100 mcg and felt dramatically better. It's in process now, and I wish I had not wasted four years of my life on this med."

2 / 10
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  • Thy...
  • Taken for 1 to 2 years
  • January 6, 2023

For Underactive Thyroid "Cytomel is amazing. I was on Synthroid (levothyroxine) for a while, and I still felt terribly hypothyroid. Then got into Armour Thyroid and became a functioning human again. Then added Cytomel to my Armour, and now I can say that I have my life back. It’s a shame that doctors are hesitant to prescribe T3 medications like Cytomel and Natural Desiccated Thyroid (NDT) like Armour. Synthroid barely ever works for anyone, and they make it so hard to get the medicine that actually helps. Big Pharma wants to keep us all sick and on ineffective medicines. I had to go to three different endocrinologists before one allowed me to start taking Cytomel. Take control of your life, people! Pro tip: if you feel jittery and hyperthyroid on one dose of Cytomel, and then after decreasing it, you feel hypothyroid, you need to multi-dose the higher dose. That means you need to take more than one dose a day! It being spread out will keep you from being jittery and hyperthyroid."

10 / 10
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21 Report
  • Clc...
  • Taken for less than 1 month
  • December 27, 2020

For Underactive Thyroid "I gained 25 lbs on an antidepressant over 9 months. I have tapered off, but no weight loss. Have some fatigue, low temp. Doc said, although the rest of the blood panel of tests was okay, he would like to see my Free T3 around 3. It was 2.56. I took my second dose this a.m., 5 mcg. Same both days. Anxious, dizzy, feel like I'm weak in my legs. Tearful - almost foggy. Doc said it was a low dose and I might feel better, or notice zero change. No more for me... I don't like the way it makes me feel."

1 / 10
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18 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.