Tirosint for Hypothyroidism, After Thyroid Removal User Reviews

• Bos...
• Taken for 5 to 10 years
• August 31, 2019

"Been on Tirosint for 7 years after switching from other forms of levothyroxine. Been doing great on it, with small dose changes when needed. 4 months ago, was feeling unwell, endo tested me & my TSH was highest it's been since before I started Tirosint. We increased my dose, I'm now worse with full hypo symptoms that are affecting all areas of my life & functioning (intense pain, fatigue, brain fog, menstrual issues, etc.). Just had my thyroid panel & my TSH has climbed HIGHER on a Tirosint dose increase - opposite of what should be happening. Hasn't been this high since my thyroid was removed. I contacted the Tirosint manufacturer to see if the formulation has changed - NO RESPONSE. Will contact all the necessary channels to find out what's going on. It seems obvious that it must be the meds, since my issues coincide with their packaging & capsule sizes changing. I'm livid that they haven't responded. People's lives are at stake. Those without thyroids NEED effective hormone replacement to LIVE."

• DCG...
• Taken for 5 to 10 years
• June 28, 2020

"I went on Tirosint when Levoxyl stopped working after they changed the formulary. It worked great until March or so of this year. Now my hair is falling out, I’ve gained 8 lbs., my temp is 96, I’m exhausted, etc. Because of the pandemic, I didn’t figure it out right away. Obviously hypothyroidism and I’m so bummed. Awaiting test results and a consult with my doctor. What did they do to Tirosint? Synthroid or Levoxyl don’t work for me. What do I do next? What a nightmare."

• KAa...
• Taken for 1 to 6 months
• September 19, 2019

"Thyroid removed in 2014 due to cancer. Have been on every medicine out there. I was happy on Nature-Throid until a change in 2018, and it quit working. Not happy with NP or Synthroid. Just tried Tirosint 6 weeks ago. Noticed a lot of aches and pains have disappeared. Although this med is absorbed much easier for me, and I had to start skipping a day every 5th day on 125. If I didn't - I experienced pains in lower legs and other signs of overtreatment. I just got my blood work, and TSH was 1.19. So it's working very well. Could probably go on 100, but Dr. is happy with what I am doing. I had a small amount of Hashimoto in my removed thyroid. This med is stronger than levo, so be careful when switching. I was on 135 levo before the switch and started on 125 of this med, and I could tell it was still too much. I even eat breakfast with mine. It doesn't even bother it. So those with gastro issues, try eating with your dose. I'm happy and hope it stays this way for a while. I'm tired of switching meds."

• Lov...
• Taken for less than 1 month
• November 23, 2016

"I was on levothyroxine for a year after my cancer surgery/thyroid removal. It was the worst year of my life. I was seriously hating life because I hurt every single day. Muscle aches, swelling, every symptom you can imagine. Weight gain was the worst. I fired my endo and waited two months to see the new one. If I wasn't married, I'd propose to the man. In three weeks, my life has changed. I can go to the gym and not feel like I have been hit by a truck. No muscle aches. I have lost 9 lbs. Brain fog is lifting. I sleep better, and I don't feel like a 47-year-old stuck in a 90-year-old body. I will pay ANY amount of money, and I will NEVER go back."

• thy...
• Taken for 2 to 5 years
• February 7, 2024

"Tirosint is the lesser of all the evils for me. When my levels are good (below a 2), then I feel wonderful and am functioning well. If they dip, I feel like everything goes haywire. If I'm too suppressed, my period goes crazy. Serious anxiety in the form of obsessive worrying. If my dose is too low, my period just stops, my face puffs up. I can't sleep. Neurological issues. Acne. I do better having my levels checked every 3 months. I skip my dose on lab day and take it immediately afterwards. This has kept me pretty close to the 2 range. I'm a woman, so healthcare professionals disregard me and my symptoms, so I'm just writing this hoping it will help another woman."

• Kat...
• Taken for 1 to 2 years
• June 12, 2019

"I have been on Tirosint for 21 months along with a T3 only med. But for the past month, I have been exhibiting hypo symptoms when nothing else has changed. This is for the 100 mcg dosage. I called the number on the box and reported my symptoms. The woman said she has been getting other complaints recently, too. What's important to note is that in December 2018, Tirosint changed distributors. I think there is a batch consistency issue. I am sleeping 12 hours a night, having depression (nothing changed in my life), increased joint pain, and severe fatigue. The only reason I rated it an 8 is because for the first year and a half, with the old distributor, I had no issues. I REALLY don't want to change thyroid meds again. That would be devastating."

• 24a...
• August 19, 2013

"I started Tirosint after Levoxyl was taken from the market. It is the best. I take this in combination with Liothyronine. Aside from insomnia, which I have experienced with every other medicine as well, and I've taken them all, this is the best I've felt in years."

• Ree...
• August 11, 2019

"Graves disease/RAI diagnosed 2004. Today is day 19 on Tirosint. I have rapid heart heartbeat, shortness of breath, waking up gasping for air, body sore in the weirdest places, hips, calves, under both armpits, as if they are bruised. Major anxiety, I feel like I am vibrating throughout my entire body, shaking so bad I sliced my finger open cutting veggies earlier. Zero history of any sort of anxiety issues. Have experienced a few episodes of leg cramping, but the seized muscle from my neck down into my shoulder on the left side is very painful. Maybe the dose is too high because it is a concentrated, more natural version, which I understand, not chancing anything more serious. I have read wonderful reviews about this medication, and we are all different, this is simply my experience."

• Anonymous
• Taken for 1 to 6 months
• April 26, 2017

"I have felt horrible for ten years since they removed my thyroid. I was told I didn't metabolize Synthroid properly. My doctor tried everything with negative results. I recently came across a published paper on the NIH website, and it mentioned Tirosint. My doctor had never heard of it, but she was willing to give it a try. That was two months ago, and I have never felt better. I know the drug is expensive, but there is a manufacturer's coupon online. I ended up paying $35.00, but I would gladly pay full price. That's how good it is!!!!"

• sor...
• Taken for 1 to 6 months
• May 4, 2019

"I loved it for the first month. Then, I developed agonizing headaches and chest pains. Had to go to the ER four times in pain. They could not do anything. Seven months later, I am still in pain and have to go to a gastro specialist to find out what is wrong in my stomach. It is really scary. I think it gave me some kind of ulcers in my stomach."

• Mis...
• August 29, 2020

"I was on name brand Synthroid from 2008 until 2019, my doctor switched me to Tirosint thinking that I would have less heart palpitations and better absorption. I was on 200 mcg of Synthroid, TSH was 0.01, I am now on 112 mcg of Tirosint with a TSH of 0.1. I gained a significant amount of weight, so my endo doctor added 5 mcg of T3, I have not lost any of the weight. Since starting Tirosint, my weight has increased from 116 lbs to 130-131. I exercise and move a lot and do watch what I eat, although I do allow sweets in moderation as I always have. I have also noticed an increase in hair loss, a lot of hair loss, and very dry hair, thankfully, I have thick hair, but the dryness is awful. Long story short, I don't believe Tirosint is the right medication for me as I have gained so much weight and lost a large amount of hair, even with the added T3, which didn't help to change the weight issues. I will be requesting to go back to name brand Synthroid with the added T3 to see if this helps."

• Anonymous
• August 6, 2012

"I could not get my T3 or TSH regulated before this medicine, and now it is stable. I take this and wait about 1 hour before I eat, so I haven't had any stomach problems. It is easier for the system to absorb since it is a gel cap. If your doctor is reluctant to try one of the desiccated thyroid medicines, this may be an alternative for you."

• Jen...
• Taken for 10 years or more
• April 13, 2019

"Same as the comments below. Tirosint is the only thing that has worked for me, and I’ve been on it for 10 years... but I just went to pick up my first prescription in 2019 and found that even after jumping through the hurdles of getting my insurance to entertain covering it, they will only cover $30 of the $150 per month. It’s too unaffordable, so I have no idea what I’m going to do now. Shame on this company for increasing prices when healthcare and insurance are already a joke."

• Gen...
• Taken for 1 to 2 years
• September 1, 2022

"Tirosint has changed my life. I have been sick and tired for more than a decade. I had both Hashimoto’s and Graves. Along with hyperparathyroidism that caused me to have constant kidney stones. All of this made life so miserable, I almost gave up. Eventually, I had a TT with parathyroidectomy. For 2 years, I fought with generic Levo and other thyroid replacement meds. I was so exhausted that I would fall asleep everywhere. My muscles ached like I had the flu, my breasts hurt like I was pregnant. I had migraines, constipation, my hair fell out, and I eventually filed for disability. I couldn’t take the correct dose because the meds made me feel worse. Then my PA suggested Tirosint. Within 2 weeks, I felt 15 years younger. The symptoms were all gone. I slept normally, could do things I hadn’t done in 15 years, and I got a job! I haven’t felt this good in so long that I want to tell everyone about Tirosint. If you feel even slightly icky on something else, try it! It is worth every penny!"

• M77...
• Taken for less than 1 month
• January 10, 2013

"Within 30 seconds after taking this medicine, my stomach becomes a volcano. I think it is something in the coating rather than the medicine itself. Discontinued use and am now on Armour 45 mg and Synthroid (not generic) 50 mcg. Am still working on blood levels, but after stopping Tirosint, my stomach problems ceased. Too bad, I was really excited by this new medicine."

• Luv...
• Taken for 1 to 6 months
• September 2, 2020

"22 yrs since my cancer. Finally, I am doing well on Tirosint. Been on it for 8 weeks and 1 dosage change since my 6 wk TSH blood test. Feel better so far. I have been on many different dosages of Synthroid and levothyroxine, and there was never the same dosage for longer than 6 months. I am hopeful in finding the correct Tirosint dosage. Too many fillers in Synthroid/levothyroxine. My new endocrinologist and last endocrinologist suggested Tirosint."

• Jac...
• Taken for less than 1 month
• February 27, 2020

"I took my first dose of Tirosint in the morning, and within a half hour, my ears started ringing, and I got a bad headache. By the time it was bedtime, I felt so nervous and shaky that I never fell asleep. It was an awful experience. The next day, I went back to my Synthroid."

• Sle...
• February 17, 2012

"This is the third medication I have been on since my thyroid removal. Tirosint seems smoother than Synthroid. However, I have had a lot of gastrointestinal issues and sleep issues while on Tirosint. My quality of life is now very poor. Since Tirosint is better than the other two medications I tried, I will remain on it."

• Jew...
• Taken for 1 to 6 months
• July 27, 2018

"Had started on Synthroid after thyroidectomy. Felt terrible for 2 years. Went on WP Thyroid & was doing fairly well on that for 2 years until the shortage. Started out on 112 dose. This was too high, but so far I'm feeling good on 100 dose. Better than when I was on any of the 3 desiccated thyroid meds I had tried (WP, NP, Naturethroid). So glad they make this! My only comment is 28 pills in a refill. I get mine every 90 days, so I'm shorted. It's not logical."

• Lad...
• Taken for 2 to 5 years
• July 11, 2023

"I've been on Tirosint for roughly 3 years. I was on NP before, and Synthroid before that. I had a TT 8 years ago. I've lost nearly 50 pounds. This is the most normal I've felt after my surgery. I still have some dislikes about Tirosint, but I choose this over the others. One of the things on Tirosint is if my levels are off, even just a smidge, my menstrual cycle will go haywire. Sometimes stopping altogether. I also feel I deal with more anxiety. This was something I noticed after my surgery but is more prominent on Tirosint. I try to counteract that by taking an omega supplement. Also, I started to develop hives just a few hours after taking it. The endo said Tirosint wasn't the cause, but I had literally fasted from everything but water for 48 hours to try to figure the hives out. After speaking with the pharmacist, they advised me to take it with coffee first thing in the morning. That did the trick. Tirosint is very potent, so have labs checked every 4-6 months."

• Jos...
• August 1, 2016

"After trying three different medicines and a countless number of dosage combinations, we found out that my body was not absorbing the tablets properly, and the gel capsules allow my body to absorb the proper amounts. After having thyroid cancer at 15 and not being able to find anything that really worked, I'm glad we tried this. The only downside is the cost since it is almost triple what I have been paying for every other medication."

• Dre...
• Taken for 5 to 10 years
• November 27, 2017

"I've had my thyroid removed for over ten years now. I've taken generic thyroid medicine, Synthroid, and now Tirosint. The dye in my Synthroid kept me from getting regulated. My body responded well to Tirosint for about 5 consecutive years. Due to insurance changes, I got off of it last year and got back on this year when my physician made a few calls to assist me. To my dismay, Tirosint is not working for me, even with me taking Cytomel to help me digest and absorb it. I'm tired, have thinning hair, levels are at 8.999, and I'm sweating with every movement. I'm quite disappointed that I can't get regulated."

• Dar...
• Taken for 1 to 6 months
• September 4, 2021

"I have Hashimoto's, and I've had half my thyroid removed (thanks to Midwest doctors who never even tested for Hashimoto's before assuming it was cancerous and removing it…). Anyway, I've had a horror story of a life with my thyroid. I went years after they removed half with no medication at all because they told me my other side would work on its own. It didn't. Lost babies, felt like rubbish for years. I read all the stories on the internet that said Armour was the best, and I was pregnant and didn't want to lose another baby, so that's what I did. I was on Armour from 2010-2021, and for some reason, Armour just stopped working for me in 2020 despite huge dose increases. Switched to Tirosint and Cytomel combo, and it's been 5 weeks, and I don't think my dose is perfect yet, but I'm becoming more regular and less constipated, my breasts aren't sore all the time, and it's day 28 of my cycle, and I don't feel like a run-down mess!!! Tirosint is awesome!!!!!"

• Car...
• Taken for 10 years or more
• July 18, 2021

"After other useless generics, name-brand Tirosint was most effective. Known as the hypoallergenic, it has no dyes and weird additives. Worth the name-brand money. My thyroid removed in 2001. Give it a couple of weeks to level out. Covered due to the failure of others, have the doc get a drug exception."

• Ret...
• July 5, 2021

"I was on generic levothyroxine for a couple of years and developed wheezing. When I received inhalers and even nebulizer treatment, it had adverse effects and worsened my asthma symptoms. I read about Tirosint and persuaded my PCP to prescribe it. I have to pay $80 every month out of pocket. My asthma is completely gone. It was drug-induced, probably some fillers in the generic levothyroxine caused it. I wish my insurance company would make it less expensive."