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User Reviews for Lamotrigine

Also known as: Lamictal, Lamictal CD, Lamictal ODT, Lamictal XR

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Learn more about Lamotrigine.

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User Ratings

10
   
44%(30)
9
   
24%(16)
8
   
11%(7)
7
   
2%(1)
6
   
3%(2)
5
   
3%(2)
4
   
2%(1)
3
   
5%(3)
2
   
2%(1)
1
   
9%(6)

Lamotrigine Rating Summary

8.0/10 Average Rating

69 Ratings with 67 User Reviews

What next?Compare all 217 medications used in the treatment of Depression.

Reviews for Lamotrigine to treat Depression

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"This drug is a live saver for my Major Depression. Has me back to feeling like myself."

   
10

bthomasdickinson (taken for 1 to 2 years) November 30, 2017

2 users found this comment helpful.
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"Absolutely saved my life. I've tried numerous drugs over 15 years and this is a miracle. No side effects whatsoever. I feel better than I ever have in my life"

   
10

MaryKathryn2018 (taken for 1 to 6 months) November 29, 2017

3 users found this comment helpful.
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"I've been on 100mg Lamotrigine for 9 years now. I started it after a major depressive episode. No side effects that I can tell, which is a huge boon compared to SSRIs (weight gain, feeling hungry all the time, and no libido) and Welbutrin made me feel like I was on speed. It is a mood stabilizer, not so much an AD. I went from having anxious and depressed episodes every few weeks to having them rarely. After a few years I tried upping my dosage to 200mg, but I felt too 'flat' emotionally and went back to 100. I still feel some depression, but the cycling is greatly reduced. Really a miracle drug for me. I recommend titrating up (and down) very slowly, to avoid getting the rash. It takes a while , but it was so worth it for me."

   
10

Jordancc (taken for 5 to 10 years) November 27, 2017

1 users found this comment helpful.
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"I have taken Sertraline, Paroxetin, Wellbutrin, Brintellix, Mirtazepine. But lamotrigine is perfect in combination with paroxetine. I am glad that this medication was created."

   
10

Anonymous October 16, 2017

8 users found this comment helpful.
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"I've always had depression as a struggle of mine. Fast forward at a low point my doc put me on numerous anti depressants throughout a period of 2 years that temporarily helped me to be functional before the extreme fatigue returned. We started lamictal. After 4 weeks I went up to 50mg. At first some tummy issues, wasn't prolonged. I'm currently on 50mg and it's been 6 weeks. I've felt huge difference that I can clearly see. I have ADHD too. I'm much more focused. My intense cravings for sweets is gone. I'm much more positive. I'm able to focus on the long term. I'm less tired & my anti-d & my concerta is working now! I've lost weight and not needed to sleep during the day. Mornings are easier. At night, I'm ready for bed :-) hope it stays"

   
9.0

KaraCmp (taken for 1 to 6 months) October 9, 2017

15 users found this comment helpful.
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"I stared on medication in the middle of my divorce and I stared to take Abilify then, I stopped since it was not covered by my insurance anymore. I took Risperdal which messed up with my hormones and I had my prolactin levels super high they found a pituitary tumor in my brain ( adenoma) well I had to go for another type of treatment for that. Then, I took quitapine for sleeping I was not able to sleep for very long time Quitapine helped me to sleep but make me gain weight , hallucinations, and bad drugs for eyes. I stared on Lamotrogine since I started to take this everything was fine but after a while passing a year I notice some changes like red rash on my skin they were over my butts and my arms. I gained some weight and loosing my hair."

   
5.0

E23Cli34se55 August 19, 2017

1 users found this comment helpful.
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"No more feeling frustrated, and no more outbursts. I take klonopin also. Only thing is orgasm is hard to achieve. Erections are fine, but orgasms are long to get to."

   
10

Easy123 August 18, 2017

3 users found this comment helpful.
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"Note - I take Lamictal for treatment resistant depression, but that wasn't offered as one of the condition choices. Lamictal has been a godsend. My p-doc prescribed it to augment the Effexor (300 mg/day) that I take. As others have noted, you have to titrate up gradually on Lamictal so it can take about six weeks (in my case) to start seeing improvement. At 75mg/day I definitely began to notice a change for the better and at 100mg/day (which I've been taking now for 2.5 weeks) the positive impact has been dramatic. I don't wake up every morning plagued by anxiety and negative, self-loathing rumination. I am actually happy which hasn't been the case for many years."

   
10

miracledrug (taken for 1 to 6 months) August 8, 2017

21 users found this comment helpful.
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"After falling ill with major depression this past Spring, my doctor prescribed Lamectil. I noticed a positive change at 50 mg , and am now up to 75 mgs. I'm looking forward to titration up to 100 and hope that will be the most effective dose, as with fibromyalgia, I am very sensitive to meds. This med has also changed my life as I became non functional, prior to taking it. I pray the positive effects last, as I was in a very dark place without it. I take my dose in the morning, as I was having difficulty sleeping at night ( and take melatonin and benzos) for that. My appetite has also not yet gotten back to normal, but I am taking in enough calories to maintain the weight I lost during the depression."

   
10

Cassidy Shane August 8, 2017

8 users found this comment helpful.
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"Looking back, I think I've had anxiety and depression most of my life. When I started to have mood swings and also feel like crying almost every day, I finally decided to seek treatment. This was about 5 years ago. The generics for Welbutrin and Lexapro helped, but I still had many times when I was depressed and somewhat suicidal. My psychiatrist tried prescribing several add-on meds, but either they weren't effective or caused side effects like weight gain. I am now on 100 mg of lamotrigine, and I don't think I've ever felt better! I am cheerful, motivated and feel like myself, without anxiety or depression. Only side effect is that I sometimes feel itchy on my scalp, arms or legs. No rash."

   
9.0

MomKath (taken for 1 to 6 months) July 26, 2017

15 users found this comment helpful.
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"It caused me worsening depression, facial acne and messed up my comprehension! I could barely come up with words to say. Be aware that depression is an adverse side effect and should be stopped immediately as it only gets worse. I am 21 years old and experienced induced mania because of SSRI's. I was prescribed Lamictal 25mg after a psychotic attack. I took it for only 10 days because the depression got significantly worse day by day, especially when I upped the dose, to the point where I didn't even know who I was . Plus it made me numb and nothing was exciting."

   
2.0

Lela3338 July 10, 2017

4 users found this comment helpful.
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"Have had major depressive disorder with borderline bipolar since I was 9, now with added anxiety. Antidepressants never worked for me. I am also sensitive to medication. As my episodes have gotten worse, my doctor thought to try me on Lamotrigine. I had to go very slowly up, and at first couldn't even tell if this was working, until I went up to 75mg, then I crashed. My dark thoughts took over me, I couldn't stand trying to wake up or get out of bed. My hydroxyzine that usually helps calm me a bit, was no help at all. I was told with being on the low dose that I could just stop it, but then I had bad withdrawal symptoms that took over 2 weeks to calm down. I cannot recommend this medicine."

   
1.0

catblue (taken for 1 to 6 months) July 7, 2017

3 users found this comment helpful.
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"Wow what a difference. I've tried 4 SSRIs, 1 SNRI, Wellbutrin (Made me irritable and couldn't sleep), Viibryd, different ADHD stimulants, and the list goes on. Currently, I'm on sertraline (Zoloft generic) 100mg and it was working out okay, but still struggled with my temper and depression. After 5 weeks, I'm finally on lamotrigine (Lamictal generic) IR 100mg once a day. It took 3 days after I started the 100mg to notice a big difference in my behavior. Side effects you might notice while starting it are Dizziness (minor), slight sedation or tiredness, and depression. My depression is now gone. I believe it was my brain adjusting to this miracle of a medication."

   
9.0

Vibro (taken for 1 to 6 months) June 25, 2017

18 users found this comment helpful.
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"I never write reviews but this time I had too. I am 24 years old and had depression since I was in fifth grade. It was manageable up until I graduated high school. When I started working in taking on more responsibilities I started getting depression really bad . To the point I cannot handle anything anymore. I tried Venlafaxine for 5 years. It worked good on the mood and the depression but as it went on the side effects kept getting worse and worse which made me stop taking it. Terrible withdrawal. I then took mirtazapine for 6 months didn't work. Now taking lamotrigine at 100 mg - (after upping slow) Took about two months, I have never felt this good in a long time! No more worrying no more depression! I highly recommend this!!!"

   
10

Patrick1969 June 6, 2017

24 users found this comment helpful.
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"So far, at a dosage of 200mg/day, this medication has turned my life around. Although I haven't been diagnosed bipolar, it has been enormously helpful and has destroyed my depression and anxiety. It took a while to increase the dose but it was 100% worth the wait!"

   
9.0

houdini95 June 5, 2017

18 users found this comment helpful.
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"The medicine seemed to work okay. However after two weeks of 25 mg I increased to 50 mg and after 6 days of 50mg I was admitted in the hospital with aseptic meningitis. I didn't know at time it was from medication. I came home restarted medication and then started with rash so stopped medication. When I called my psych to tell him about rash and about recent hospital stay he told me Lamcital causes meningitis. I was told to stop medication immediately."

   
1.0

Renee12280 May 24, 2017

13 users found this comment helpful.
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"It only took 4 doses of the 25mg starter pack to cause major issues for me. I experienced sleep disturbances that exacerbated my depression and anxiety. It's been a few days since my last dose and I'm still struggling with insomnia, panic and frequent tearfulness."

   
1.0

sleepygrl May 17, 2017

6 users found this comment helpful.
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"Hello all: My daughter has had some form of depression since high school. Where she has had therapy it wasn't recommended that she take medication. She has a safety plan in place, food, exercise etc. She seemed to manage the depression pretty well until college. She had never been on any antidepressants before and her first trip the the pshyc. they put her on lamictal 25 mg. My fear as a mom is that she is depressed not bipolor. She's only been on it for a week and where she presents more snippy/angry in her depression she has cried everyday on this medication. We don't have a follow up for a few weeks does anyone have any advise?"

   
5.0

Mom seeking advise April 26, 2017

6 users found this comment helpful.
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"I have been seeing a counselor regarding some personal issues going on. She thought I was mildly autistic or had some sort of social disorder because she couldn't read my body language. I am in my mid 40s and work in PR. Nobody has ever brought it up. She said to go to a behavioral specialist anyway to see what they says. The Specialist diagnosed me with Cyclothemia, which seems to be bipolar light, or rather just moody. Certainly the latter is true. I'm not a fan of meds but this has really changed me, for the better I believe. If I forget to take it, boy can I tell. Not sure if it's withdrawals or how I used to feel. If I lose my insurance I can keep taking it. It's cheap thank goodness."

   
8.0

DJ_1970 April 26, 2017

13 users found this comment helpful.
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"I guess I can't say much about it just yet, I've tried almost every antidepressant out there with basically no luck, so my doc suggested we try lamotrigine. (and funny how my review starts out like any other). I'm up to 50mg now, and I don't know if I notice any difference at all, no side effects either thus far, so at least thats good. if I notice any difference, I will update."

   
3.0

mindmaze (taken for less than 1 month) April 22, 2017

7 users found this comment helpful.
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"Hi my Dr started me on this today. I have mood swings, low energy & depression. I am scared too death of medicine. I read the reviews & that has helped ease some anxiety...but I am still a little scared. Thank you"

   
7.0

Christinadawn April 3, 2017

11 users found this comment helpful.
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"I was very hesitant about adding any new medication to my relatively mild SSRI & Klonopin regimen, but despite this combo, my depressive symptoms not only persisted, but grew more intense during active phases. I say "active" meaning "severely more depressed than usual." I *alway* felt depressed, but every few months, I would fall into a debilitating state where I could barely function, couldn't leave the house, cried all the time, just hated myself, and it got to the point that getting up and showering felt overwhelming. I started Lamictal, felt nothing at first, but after 8 days, I literally *snapped* out of it. I felt normal & hopeful for the first time ever. I would definitely give this a chance if your doctor feels it is a good choice."

   
9.0

ShannyCat March 23, 2017

33 users found this comment helpful.
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"I have had depression my entire life, and Lamictal started working for me within a month, or so. This medication hasn't solved all my issues, but has made my depression manageable. I still have to make sure I'm getting regular exercise, eating well, getting enough sleep, spending time in the mountains and in the sun, and showering regularly; if I don't, I will cycle back into a depressive episode. I know this is probably common for the general population, but I wanted to make it clear that before, those activities wouldn't curb my depression in any way. I give this 9/10 as it has caused my eye sight to decline, have noticed some gum recession, some sexual side effects, as well as some hair loss (supplementing with selenium has helped)."

   
9.0

ClaireBear4 (taken for 2 to 5 years) March 19, 2017

27 users found this comment helpful.
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"This drug is a live saver. Has me back to feeling like myself."

   
10

bthomasdickinson (taken for 1 to 6 months) March 15, 2017

17 users found this comment helpful.
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"After reading so many positive reviews on this site, I decided to try Lamotrigine. I found it to be the most effective long-term drug for depression and mood stability. Having tried antidepressants and most mood stabilizers, this was the best drug for me. It does not make me tired or drugged up - just substantially reduces depression. Reduces overall depression, SI, obsessions and anxiety. Slowly went to 200mg/day as I couldn't feel much difference at 100. I had to switch to the brand name as generic was giving me stomach problems. Otherwise no side effects."

   
10

Canada345 (taken for 6 months to 1 year) February 19, 2017

29 users found this comment helpful.
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