Insulin degludec for Diabetes, Type 1 User Reviews (Page 2)

• Izz...
• Taken for less than 1 month
• November 4, 2018

"I’ve been on Tresiba for just under a week (made the switch from Levemir) and have mixed feelings. Although it’s still early days in terms of fine-tuning the dose, I feel like it would probably be a great option in terms of enabling more consistent and lower blood glucose levels. HOWEVER, since day 3, I have felt absolutely dreadful. I have had chronic diarrhea that just doesn’t seem to go away. Awful, agony stomach pains. I’ve felt exhausted, far beyond what I’ve ever felt before. To the point where I feel like I could sleep 24/7. And I’ve felt breathless for no reason also. I really want Tresiba to be a viable option for me, but unfortunately, it looks like it’s the most likely cause of these symptoms. So I’ll be on the phone to my diabetes team tomorrow, it looks like another switch will be necessary. Just hoping I’ll start to feel remotely normal soon!!"

• Tpa...
• Taken for 6 months to 1 year
• February 28, 2020

"It's an ok insulin for sugar control, and to each their own. I had a problem with higher morning numbers than when on Levemir, but it did work more through the daytime hours than Levemir. My main problem was not being able to sleep throughout the night due to CONSTANTLY URINATING (more than 4-5 times a night!!) even though my numbers were well within range. My doctor said it couldn't be Tresiba causing this, but literally the first night I switched back to Levemir, I only used the bathroom once through the night, and that was even with waking up to a bg of 192! I also had the usual stuff like major weight gain and brain fog. I would honestly never use it again."

• Hal...
• January 12, 2017

"I've been on insulin since 1985, most recently Humalog and Lantus. I've been taking Tresiba for 6 weeks now, 30 units at bedtime, and I almost never use the Humalog unless I eat something high in carbs. It is almost like being off the multiple shots I was on at every meal. I recently got a Dexcom CGM and can monitor my sugars constantly."

• Gol...
• Taken for 1 to 6 months
• July 25, 2019

"Right before the 4th of July, my endo had me try the Tresiba insulin. I had been on fast-acting prior because of the pumps, so I had nothing to compare this with in terms of results. Tresiba worked very well on getting my sugars in range, and I even had several nights of perfect 117 sugars throughout. This insulin is a poor man's pump - however!... However, I experienced all the worst symptoms like headaches, foggy brain, flu/cold-like symptoms (honestly, I attributed it to my running around like a 20-year-old at age 30), but then the swollen ankles came. Swollen, tender, and my skin started feeling on fire. After I realized this was all from my insulin, I called my doctor's office and told them to switch me off immediately. Which they did, and I switched to Levemir. Here's to hoping it works well. With my review and reading others, I am convinced the Tresiba needs to be assigned to type 2's only because they seem to have better luck than type 1's are on this brand."

• Vol...
• Taken for less than 1 month
• August 15, 2016

"I have been a diabetic for 51 years. I used Lantus as my bedtime insulin and Novolog on a sliding scale for meals. I was taken off Lantus by my endo and replaced it with Tresiba. The first day, I noticed dizziness, the second day it was worse. On the third day, I can't walk across a room, for I am going sideways. I am so sick, for I feel like I am on a merry-go-round nonstop. My blood sugar dropped to 25 this morning, and with the dizziness and this, I was in bad shape! Back to my Lantus I go, and Tresiba is in the trash where it belongs!"

• Joh...
• Taken for 2 to 5 years
• June 26, 2017

"I have been on Tresiba since June of 2015. After a couple of weeks, I adjusted fine to Tresiba and love it. However, in September of 2015, I began to develop stomach problems. At first, I didn't think anything of it, however, it has only become worse over time. I had a colonoscopy done in June of 2016. The doctor found nothing wrong. I also had an MRI done later last summer in which I had to drink a dye. Once again, nothing was found wrong. In June of this year, I had an upper endoscopy, and once again, nothing was found. I feel like my stomach is going to explode. I feel nauseous, however, I have never thrown up. Just wondering if anyone else has had these problems."

• Sky...
• Taken for 1 to 6 months
• September 10, 2019

"I was diagnosed with Type 1 diabetes two years ago at 36 years old. Recently I switched from Levemir to Tresiba, as recommended by my endo, to see if my lows would minimize during physical activity and keep me level. Unfortunately, my sugars stayed somewhat high, 200-250 mg/dL, for the two months I was on Tresiba, and I developed a rash in my lower back that was gradually getting worse. My endo said she never encountered anyone with a rash not at the injection site, but if I felt more comfortable, then to switch back to Levemir. I also developed these dry, white patches on my skin. Again, my endo wouldn't say it was related to Tresiba but advised me to go to a dermatologist. I was then told it was lichen sclerosis. I also gained weight on Tresiba. Doctors should be more aware of perhaps lesser-known side effects. It seems as though they are completely clueless. Good luck, everyone, on managing your disease."

• Mia...
• September 22, 2016

"This med is awful for me. I am more out of control than I was on Lantus. Terrible headaches in the afternoon and evening. My hypo awareness is worse. If it wasn't for my CGM, I would probably be in the hospital or dead. I think new meds are a great thing, but when your insurance renews in Oct-Nov, people can no longer afford it due to copays, so they have to change back to a more affordable med and start all over again. It's a terrible way to live."

• Joh...
• Taken for less than 1 month
• December 29, 2015

"Very, very happy. Only one shot a day, and this stuff is smooth. Don't have to take as much Apidra. Been taking it since 12/6/15. Already reduced my total insulin intake from 48-50 units to just 40. Only take 30 Tresiba in the morning, and if blood sugar is 70-100, hardly no need for Apidra with my normal breakfast. Probably will slowly come down on Tresiba. This is a breakthrough."

• Bet...
• Taken for less than 1 month
• January 9, 2017

"I've been a type 1 for 3 years now. My glucose levels haven't been well controlled. My last A1C was 12, the best was an 8. My work hours fluctuate, taking a shot or eating at the same time every day is near impossible. I've just switched from Lantus a few weeks ago, had to cut my dose from 30 to 26. Tresiba is more powerful, causing lows. Not complaining, just a little scary, especially at night. It's trial and error, as the whole 'my pancreas stopped making insulin, so I have to manage the 'mimic the natural production' thing. I haven't experienced any side effects, as I've been reading in the thread. Think I have a winner. I have an endo appointment soon. Luck!"

• PA-...
• Taken for less than 1 month
• June 21, 2018

"I've had Type 1 for nearly 40 years. My endocrinologist recommended Tresiba to replace Lantus. I took it for one month. After 2 days, I saw no changes or improvements in blood glucose levels. As the fourth day approached, I figured the flu was why I had been having blood sugar fluctuations. After a week, I seemed to have stomach issues and nausea for days, and then I had headaches and blurred vision and felt like a train wreck. After 2 weeks of symptoms, I began to wonder whether I even had the flu. After 3 weeks of symptoms, I decided to read the medical insert thoroughly, only to discover that these flu symptoms, blurred vision and dizziness, and stomach issues were all SIDE EFFECTS. I called the endo office and spoke with a doctor on call, who agreed that maybe I should just switch back to Lantus and see how I felt. I took Lantus that evening and felt better within 12-24 hours. My endo never called me back, so I won't see him again. Maybe he gets kickbacks to market this."

• Typ...
• Taken for 10 years or more
• August 22, 2020

"I have had several Tresiba pens that do not work at all, and I have to supplement with bolus shots every 1-2 hours and fast until a new pen takes effect 1-2 days later. I do not know if it is a lot issue or a refrigeration issue during shipping. I store it in a refrigerator within 5 minutes of picking up the chilled insulin from the pharmacy. I have NEVER had an issue similar to this with any other insulin, including Lente, NPH, Regular, Novolog, Levemir, Lantus, or Humalog over the last 44 years."

• Cat...
• Taken for less than 1 month
• September 14, 2020

"Awful, awful, awful. I have had diabetes for 35 years and have NEVER felt so unwell on any insulin before. Today is the last day I will take it. Roller coaster sugars, eating to keep up, weight gain, chills and sinus problems, soooo moody, going in the bin tonight, where it belongs."

• Chr...
• July 11, 2019

"I was changed to Tresiba from Lantus last October (2018). Within two months, I developed lichen sclerosis. My diabetic doctor denied that there could be any link and was adamant that I should remain on Tresiba. Six weeks ago, I stopped Tresiba and put myself back on Lantus. My symptoms immediately abated, and today, the dermatologist told me that I seem clear. I think health professionals should be aware of this as lichen sclerosis is a most unpleasant and potentially dangerous condition."

• cat...
• Taken for 1 to 6 months
• September 17, 2020

"I have been taking Tresiba for a little over a month and have had great results. It has kept my blood sugars between 100 and 120. I still have problems with waking highs in the 160s but am still titrating according to my NP instructions. I use Fiasp for short-acting and, these together, have been a godsend to me. I am very pleased with Tresiba. I do have a CGM which makes this so much better."

• Jul...
• August 26, 2016

"I've been a Type I diabetic for 14 years and just recently (within the past month) made the switch from Lantus to Tresiba. I have had constant headaches in the afternoons since switching, and today is the second time the pen has just stopped working. I will be partially through the injection when the pen stops dispersing the insulin - you can press on the plunger, but nothing comes out and the numbers do not go down. Not having insulin when your life depends on it is the scariest feeling in the world."

• Jrt...
• Taken for less than 1 month
• April 5, 2019

"Since I have been using Tresiba for my type 1 diabetes, my blood sugar levels have gone up from my usual low of 109 to a high of 199, to now well over 600. I was wondering how long it was supposed to start working. Then, when I checked, it can take 4 hours to get into your body but should last at least 24 hours, but my levels are too high."

• Sym...
• July 22, 2016

"I have been taking 14 units each morning for the past 3 weeks. Week one, not bad, I think because of the transition from Lantus to Tresiba. Week 2, started having highs in the morning with meals and then dropping low starting around 4 pm. Week three, highs still in the morning and having to take triple Novolog (1 unit per 15 carbs), and then by 4 pm, dropping to the 40s and 50s and having to drink up to 3 8 oz glasses of OJ to level back out. This week, I am trying to split the dosage to 7 units in the morning and 7 at night. That was a fail, I ran high all night. With all these challenges, Dr. switched me back to Lantus."

• Ver...
• Taken for 6 months to 1 year
• January 26, 2023

"I have Type 1 diabetes and found Tresiba did not work as effectively as Levemir. My glucose levels stayed in the 300 range even after a dosage change. I experienced sore muscles, weight gain, a general sick feeling, and extreme fatigue. I do not recommend this medication for Type 1 diabetes."

• Emm...
• Taken for less than 1 month
• May 23, 2016

"I've been a type 1 diabetic for 21 years. I switched from Toujeo to Tresiba to try and combat the low blood sugars I have while I'm asleep. My endo said this was the only type of LL insulin that had the compound breakdown to avoid the nighttime lows. Every review (there are hardly any patient reviews for this drug) has said it takes significantly lower doses on this than any other LL insulin. That has actually not been my experience. I've had to increase the LL dose, and oddly enough, I still have those nighttime lows. Then all day, my blood sugar is higher than it needs to be. Two weeks on it is plenty of time for my body to adjust, yet I'm still having the same issues. Not impressed with this insulin. Had much more stable BS on Toujeo."

• Typ...
• Taken for 1 to 6 months
• November 30, 2016

"Went from twice-daily Levemir to Tresiba. Controlled blood sugars equally well. Did like the convenience of once-daily injections. However, I gained 12 pounds over 4 months. Cannot attribute the weight gain to anything else (exact same diet, exercise, and lab work fine)."

• May...
• Taken for 1 to 6 months
• October 28, 2016

"Been taking Tresiba about 3 months. It is really good so far. Seems to keep my sugar under control. I especially notice it does really well at the 24-hour mark. When taking Humulin N, my sugar would rise at around the 18-hour mark and continue rising until it was time to dose again around 7 a.m. The rise would be up in the 300s or 400s. Now my blood sugar does not rise at that time at all. In fact, it goes crazy low. I'm completely hypoglycemic unaware with this insulin until I actually test my sugar, and it will be in the thirties and forties. Such a strange feeling being that low and not being aware of it. Haven't had my A1C tested on it yet, but overall it seems to be working well."

• DVR...
• Taken for less than 1 month
• May 7, 2023

"Tresiba is awful. I've been a type 1 diabetic since 1986. I'd been on Lantus for over 20 years, and my diabetes was really well-balanced. My CGM time in range was usually around 90% with very few hypos and almost no serious ones. However, in a diabetes review that sounded like a box-ticking exercise, my HbA1c was deemed too low (5.9%), even though nobody looked at my TIR or the incidence of hypos. I was told to ditch Lantus for Tresiba. Nobody told me that the pharmacokinetics were different and that I had to build a therapeutic accumulation over the first few days. As a result, I swapped Lantus for Tresiba like for like, and for the first two nights, it sounded like it didn't work at all (my blood glucose was shooting up dangerously in the middle of the night, to the point I had to do a correction with Humalog). As a result, I increased the Tresiba on the second night and the third. In the morning of the 4th day, I had a MASSIVE hypo coma. First time in 25 years, and I entirely blame it on Tresiba."

• nic...
• Taken for 6 months to 1 year
• October 28, 2020

"My son, who is Type 1 diabetic, has been on Tresiba for a year, and it is the best insulin. His A1C level dropped from 9 to 5, and his blood levels are always in range. It's actually affordable and perfect for him."

• Lis...
• Taken for 2 to 5 years
• April 21, 2018

"I'm 35 and have been a diabetic for 27 years. I have been using Tresiba for 3 years now, and everything was relatively fine. I had to split my dose because of low levels at night, and even though my endo said it was not necessary, it did wonders. A couple of weeks ago, I started with low levels at night or before lunch. Thought I should only reduce 2 units. But yesterday was scary... for the first time in my life, I woke up feeling the sugar levels too high. Ended up in the ER, where I was informed I nearly had 700. I thought the batch of pens could be faulty, so I bought another batch and started my day. I had 95 when I left the ER, and after a day at home sleeping, I'm already in 200. I'm looking online if there has been a recall or other cases similar to mine."