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User Reviews for Exalgo

The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.

Condition Avg. Rating Reviews Compare
Chronic Pain 8.0
26 reviews 109 medications
Pain 7.0
7 reviews 1117 medications

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Exalgo

TMV · Taken for 1 to 2 years September 26, 2019

For Chronic Pain: “Was on exalgo for chronic pain. Got zero pain relief from 32 mg daily dose. After taking it for a year, I went off it cold turkey with ZERO withdrawal symptoms and ZERO change in severe chronic pain.”

1 / 10
Anonymous · Taken for less than 1 month September 1, 2017

For Chronic Pain: “I was on 30mgs Opana ER dailu and it was discontinued. My doc moved me to 8mg Exalgo/day. It's not working well, doesn't last 24 hours and every 2-4 hours I start getting chills and runny nose. I think I just might be on too low of a dose. Too bad I can't get in to my doc sooner.”

4 / 10
Hepzibah1 · Taken for 2 to 5 years May 19, 2017

For Chronic Pain: “I was on Exalgo for several years. It gave better pain relief than Morphine but still constipating . During that time I kept having episodes of waking in the middle of the night with a fast heart rate and cold sweats which no one could explain . Then I developed severe abdominal pain and stopped eating with a thirty pound weight loss . While doing a bowel prep. for a colonoscopy I passed five Exalgo " Ghost" tablets in my BMs . ( Ghost tablets are the left over shell of controlled release pills ) . I realized that they were accumulating in my bowels because of my severe constipation. When I changed pain meds the Night Sweats and Tachycardia stopped .”

6 / 10
Mojo72 · Taken for 1 to 6 months May 14, 2017

For Chronic Pain: “Ineffective. Hydrocodone works better for me.”

7 / 10
Tomlin_rex April 15, 2017

For Chronic Pain: “Take 12mg Exalgo after being on Methodone, Tramadol, and Fentanyl. It is a miracle drug! The pain is so reduced I hardly ever need my breakthrough painkillers. Side effects have been negligible for me. I will never come off of this medication willingly, because I don't believe a better treatment for currently exists.”

9 / 10
LORIDCOCHRAN · Taken for less than 1 month May 1, 2016

For Chronic Pain: “I started taking Exalgo about 3 weeks ago after 20+ years of trying every other opiate and non-opiate pain med with little to no relief, especially once I became immune to them. I've been on disability since 2010 and been seeing a PM doc since about 2009 and in March he talked to me about trying an IR. I researched my insurance and when I saw him in April we decided on Exalgo 24mg per day with 15mg roxi backer. They seem to be working ok, but doc told me to take both 12mg caps in the am together which I did for about a week until I read here that others were taking them at 12 HR intervals so I tried that and it seems as tho they are causing me to not sleep. I have been waking up about 4/4:30am every day since. Anyone else having issues?”

7 / 10
tonyplake · Taken for 6 months to 1 year April 28, 2016

For Chronic Pain: “I was taking 80 mg. day of oxycodone (percocet 10 mg. + 325 acetaminophen per pill ) and finally found a pain doctor who is a psychiatrist and a neurologist as well as a pain mgmt. specialist and an addiction treatment specialist. He asked how long the percocet worked for me. I said 2 to 2 ½ hours. He said based on the number of years I had taken it (4) and the increases of dosages over those years (beginning of 4 mg. 4 x day to 8 mg. 6 x day over 4 years) that I had become tolerant to oxycodone. He put me on exalgo 32 mg. extended release once/day which is hydromorphone which is dilaudid and 4 mg. dilaudid/hydromorphone (the same drug but not timed release) for break through pain 4xday. It was pretty amazing. My pain just stopped.”

10 / 10
Ps91 September 21, 2015

For Chronic Pain: “The pain management Dr prescribed morphine sulfate ( due to cost) rather than OxyContin . It was horrible. I felt loopy and sick with pain in my side . So a different Dr switched me to Exalgo SR .. What a relief! Ian finally thinking clearer . I take dilaudid for breakthrough pain and between the two , I am functioning much better. I think it is much better than OxyContin as well , because OxyContin always made me feel flushed and a bit dopey in a different kind of way. ( not as bad as morphine though) I am so glad I am getting pain relief without feel sick and doped up . I think Exalgo is a perfect match for me .”

10 / 10
Who was that? · Taken for 1 to 6 months September 1, 2015

For Chronic Pain: “Very good and fast working”

7 / 10
German automotive technician · Taken for 1 to 2 years July 18, 2015

For Chronic Pain: “I am a 30y/o German automotive technician, when I was 18 I was hit by a drunk driver. Broke my lower back in 2 places,my hip and knee. I was taking 40mg OC and breakthru meds every 3 hrs , I was doing decent until in 2008 I was involved in a head on collision which broke my neck in 6 places. The pain form that was worse than anything I had experienced before. My dr increased my pain med doses, we tried everything from MS Contin to Opana ER, nothing was able to keep my pain under control for long. Being an automotive tech just added to the misery. Finally Exalgo came out and now 16mg/day with 2mg instant release dilaudid for breakthrough, my pain is finally controlled and I have my life back and don't have to take pills every few hours!”

10 / 10
Shitty · Taken for less than 1 month July 12, 2015

For Chronic Pain: “This medication has improved my quality of life!!! I feel so much better when I take this medication. My pain is down to a 3 from being a 10. Now if I can find a doctor to prescribe it for me, my life would be so much happier. Not having to suffer everyday....I wish.”

9 / 10
New York Gal April 28, 2015

For Chronic Pain: “I am 5'. 105 lbs and was a carpenter for 6 years . I have a bad back 2 disc replaced in neck with a plate & 6 screws which gets cold and the pain goes right down my back . Have had 15 operations . Fibromyalgia and arthritis. Tried morphine and butane patches which made me sick. I take hydrocodone 10 mg 5 X day . Which only lasts 2 to 3 hrs. Grit my teeth the rest of the time (broken a few). I started Exalgo 12 mg yesterday and I started feeling better in about 2 hrs. This is a miracle, I don't hurt! There were times I didn't think I could go on and now I have a new lease on life . I hope it continues to keep working ! Happy gal!”

10 / 10
DrDPC · Taken for 1 to 6 months September 28, 2014

For Chronic Pain: “Works great, does last 24hrs at the right dose. Give the medication time if you are switching from another pain medicine to Exalgo, for myself I was on morphine sulfate 90 mg and Oxycontin 40mg. It took almost 2 months to work @100%. I was just about to give the Exalgo up and go back to my morphine and Oxycontin but now I'm glad I waited it was worth the painful wait since I have such great pain relief. I take 48 mg of Exalgo now and 60mg of Oxycontin.”

10 / 10
catten · Taken for less than 1 month July 27, 2014

For Chronic Pain: “Too strong”

DOC USMC · Taken for less than 1 month May 19, 2014

For Chronic Pain: “I was a Corpsman with a 2nd Marine infantry battalion, and I was wounded in Iraq by an IED, I broke 2 vertebrae in neck, 2 in back, 5 herniated disc's, a lot of nerve damage and shrapnel. I was wounded January 8,2008 and have been on Percocet 10mg for 6 years and have had over 60 surgeries and 200 injections and physical therapy. I have had no relief from pain. I had thought about suicide because I hurt so bad. So I quit my pain dr and went to another. He looked at all my documentation of injuries and treatments. He said simply on my first day "you have paid your dues, I'm going to give you 30 12mg Exalgo ER a month with 120 oxycodone 10mg for breakthrough pain. I have only taken for 4 days the Exalgo and I feel no pain. ”

10 / 10
Knightflyer57 · Taken for less than 1 month May 5, 2014

For Chronic Pain: “I just started on Exalgo ER 12mg's. After fooling around with Lortab AND morphine CR for years, which would only dull my pain( Shot out of the sky in Nam) as well as a major car accident, I have found or rather my fantastic neurologist decided to go with this. I have been able to sleep a full evening(8Hrs) and not wake up with a hang-over effect. I am after 26 years narcotic tolerant so I was quite skeptical about this expensive medicine. Well, I am a believer. I just pray that it will last a year or two before it becomes useless to me. An operation to repair my back only has a 80/20 chance of even helping me. 80% being the negative. If you are tired of the pill counting or a few days withdrawal which I have been through. Ask your Doc.”

8 / 10
David256 · Taken for 6 months to 1 year February 23, 2014

For Chronic Pain: “I have been taking narcotics for chronic pain for about 25 years now. I started with Tylenol with codeine and have progressed through just about everything (morphine, oxycodone, Dilaudid, Oxycontin, Fentanyl patches, etc.). My pain management doctor had me on 60 mg of Oxycontin 3 X daily and it worked (somewhat) for a while until I developed a tolerance and it too became ineffective. So the doctor switched me to 16 mg. Exalgo 2 X daily. I was resistant at first, mainly because of reducing the number of doses per day but after I took it for a few days I was amazed. I don't wake up in excruciating pain anymore and, even though the effects are subtle and come on slowly, it works better in controlling my pain than anything else I've used.”

8 / 10
suziem43 January 4, 2014

For Chronic Pain: “My pain management doctor switched me to this medicine 2 days ago. It's a miracle. I have been on everything. I was taking Oxycontin 80mg 2 x per day along with 30mg oxycodone every 4 hrs for breakthrough pain. I felt the difference within hrs. I suffer chronic pain due to my back. I've had 5 spinal fusion surgeries. ”

10 / 10
ROB24 · Taken for 1 to 2 years December 3, 2013

For Chronic Pain: “In chronic pain, since injury in 1999. Surgery did not help. Like many I was on different narcotics for years . Started Exalgo in 2012 and have found it does work. Some say it gives 24 hr relief, but I think it more of a 16-18 hr.”

7 / 10
lynikins · Taken for 2 to 5 years November 22, 2013

For Pain: “It took about 3 days for me to start feeling better but this works for me. My only issue is that I can feel it wearing off about 2 hours before my next dose (I take it twice daily), I suppose that is what the IR 's are for. But overall, it works. ”

9 / 10
lbp102 October 25, 2013

For Chronic Pain: “I have CRPS stage 3 in my left arm and left foot. I started on 16mg a day of exalgo, then up to 12 2xday, now 16 2xday for 32mg a day. I found the 2x a day was the key for this medicine since its takes a long time to start so the next dose 12 hours apart really helped. I'm just starting the 32mg a day since my crps spread to my entire left arm so I'm hoping I don't eventually get to the 32mg 2x/day.. has anyone else taken that much?”

10 / 10
RedDawn329 · Taken for 2 to 5 years August 25, 2013

For Chronic Pain: “I started taking Exalgo in June 2011 for chronic kidney/flank pain. I started with 8mg once/day. Increased to 12mg in March 2012. Then increased to 16mg in July 2013. I call Exalgo my miracle. I like taking the ER pill rather than popping pills all day long. I've tried so many different opiates, but I much prefer Dilaudid to all the others. I also take 4mg Dilaudid (hydromorphone) as needed for breakthrough pain. Best of luck to anyone suffering from chronic pain, it's a terrible way to live, but Exalgo definitely increased my quality of life, I hope it can do the same for you!”

10 / 10
Bubba 84 June 9, 2013

For Chronic Pain: “I have been in so much pain over the past 2 yrs. My neurologist has tried EVERYTHING! I have taken every medication there is. Every narcotic available. Nothing has helped except my oxycodone 15x5 a day and it just took the edge off. My doctor put my on Exalgo along with my oxycodone for breakthrough pain and I started to feel normal again. I was told I have small fiber neuropathy along with a list of other horrible things and I can say without a doubt that this medicine has been a miracle for me. I have gone from not being able to walk from time to time and being in so much pain to feeling normal again. Don't get me wrong. I still hurt but hey I can handle this hurt! What a blessing!”

9 / 10
HimmyCat · Taken for less than 1 month June 3, 2013

For Chronic Pain: “I've been on Exalgo for about 3 weeks now and the difference is amazing. I have chronic pancreatitis and the pain from that is just unbearable...the worst I've ever experienced. I had been taking 15 mg oxycodone on an every-8-hour regimen with 2 mg Dilaudid as needed for breakthrough pain. The oxycodone had lost it's effectiveness and I was having more and more pain that was becoming more and more difficult to control. When my doctor suggested Exalgo, I agreed to try it. Once my insurance authorized it, I got the prescription filled. I had to take 2 mg Dilaudid every 4-8 hours for a few days while the Exalgo build up but once it did, my pain went from a 7 to a 3 on the pain scale. Wow.”

8 / 10
Ankylosingpatient · Taken for 1 to 2 years April 11, 2013

For Pain: “Very good med! Not an instant result but starts working effectively second day of continued therapy! Surprised at result as have been on Opana ER, Demerol & everything else. Very expensive though!”

10 / 10