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User Reviews for Hydrochlorothiazide / triamterene

Also known as: Dyazide, Maxzide, Maxzide-25

Hydrochlorothiazide / triamterene has an average rating of 5.9 out of 10 from a total of 59 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 32% reported a negative effect.

Condition Avg. Rating Reviews Compare
High Blood Pressure  
5.7
44 reviews 266 medications
Edema  
6.5
15 reviews 53 medications
Summary of Hydrochlorothiazide / triamterene reviews 5.9 59 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Hydrochlorothiazide / triamterene

Kat7 June 4, 2015

For Edema: “I am on Day 3 of this medicine. I dropped 6.2 lbs. of water. I got leg cramps the first night and realized I did not drink enough water and that I needed low sodium V8 to increase my potassium levels so I don't cramp. My blood pressure is back to normal and it is great to see my ankles and legs stop swelling. On Day 2 and 3 no problems. Drink plenty of water and drink V8 or eat a banana to up your potassium.”

8 / 10
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Anonymous March 1, 2016

For High Blood Pressure: “On Day 15, of taking 1 tablet of Triamterene HCTZ 37.5 -25mg daily, here are my notes... Gradual reaction to Triamterene-HCTZ... Day 1: February 24 evening: Bad body cramps and aches that gradually started in the legs and then persisted through the entire body ended up laying down is staying in the bed the rest of the evening; very bad headaches; no fever temperature 99.0 Day 2: February 25 early evening: Felt better this day but very sore from the night before took medication then noticed an hour after taking medication and muscle aches aches came back this night it was even worse trembling with muscle aches most of the night severe headache and unable to pass bowels; cried in pain; very thirsty and dry mouth. Temperature 99.0; Day 3: February 26 did not take; started feeling better after about 12 to 14 hours into the next day body seems very weak and very itchy ; called doctors office to find out if it was OK to stop taking this medication because of reactions; did not receive a phone call back. Day 4: February 27: called the after hours number at cardiologist office around 7:30 pm Dr. Park returned call told me that the medicine probably wasn't the issue and that it sound like maybe I had some other issues going on so see my primary care physician; did not appreciate his tone and lack of concern, therefore took half of the medication and became ill very quickly this time. This time, it started with severe dizziness and lightheadedness, severe muscle cramps and aches, at times unable to walk or control my lambs; muscle cramps persisted ability to control arms and limbs came and went; new onset of stomach pain then finally vomiting while on toilet trying to pass bowels; drank grapefruit juice thinking it would counteract the med; muscle aches and cramps headache and stomach pain lasted through the night; pains lasted all night until I fell asleep; pains were subsiding; Day 5: February 28: no meds today body feels extremely sore yellowish skin and eyes leg cramps come and go and painful but not as bad as the night before; no appetite ate very little Day 6: February 29: no meds today feel a lot better although still feel very weak soreness in my right arm near the elbow lightheadedness twice during the day within three hours of each onset eating an apple seemed to help”

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duhbraz April 10, 2010

Maxzide (hydrochlorothiazide / triamterene) for High Blood Pressure: “I had tried numerous blood pressure medications. Almost all affected my sexual performance negatively, and I also experienced headaches in the morning ALL EXCEPT THIS MEDICATION! This was without a doubt the best I had used to date. Please comment if you have tried, I would like to hear from others who have. ”

8 / 10
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HowDoIHaveHTN · Taken for less than 1 month November 21, 2013

For High Blood Pressure: “I've been on this medication for two weeks and my blood pressure has definitely dropped from 150-180/96 to 118/68. My main side effect is severe nausea right after taking it in the morning. I've tried to take it with food, milk, and lots of water, but my stomach will hurt for an hour or more no matter what. Unfortunately, I just have to stick it out since I'm only 24, 5'5 and 115 lbs, exercise regularly, and eat really healthy. Also, if you're taking this medication make sure your doctor is checking your potassium and electrolyte levels. Should be done within the first month of starting the medication.”

7 / 10
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I work for yeah January 28, 2017

For High Blood Pressure: “This medicine nearly killed me, and I'm a healthy 33 year old woman who was on it for 4 days. I was prescribed 50mg of hydochlorothiazide to take instead of 50 mg atenolol which had been giving me side effects. By day 4, I was incredibly weak, mentally foggy/confused, and had severe body aches. Also started experiencing chest pains, so I went to the ER, and my EKG showed an abnormal arrhythmia. Turns out my potassium had dropped to below 2.5, which can be life threatening. I was given 2 IV bags of potassium, 2 more bags of fluids, and kept overnight. I was fine in the morning (normal EKG and electrolytes) but was told one more day on that med could have been fatal. Be careful on this drug.”

1 / 10
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failing slowly in aberdeen January 7, 2016

For High Blood Pressure: “Drink a lot of water I've been on triamterene/hctz for ten plus years and wasn't really explained in detail how serious it would be if I didn't keep hydrated , at one point they increased my milligrams and not my potassium amount and now my kidneys are affected , I'm very dehydrated , I have leg cramps that are painful and I feel like this is it for me.”

2 / 10
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4Peace August 24, 2008

Maxzide (hydrochlorothiazide / triamterene) for High Blood Pressure: “I've been on and off maxzide. When I moved to Texas they took me off it for four years. My blood pressure has been out of control until finally one doctor listened to me when I told them maxzide was the only thing will work - blood pressure is now under control.”

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Facial/Body water retension · Taken for less than 1 month December 17, 2014

Maxzide (hydrochlorothiazide / triamterene) for Edema: “I used to take just hydrochlorothiazide alone, and Maxzide is night and day difference... I take it for first time, and 2 hours later, I lost possibly 5 - 6 pounds of water... I can see my abs again. WOW! I suffer from fluid retension from uncontrolled Hashimoto's.”

10 / 10
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Anonymous November 15, 2010

Dyazide (hydrochlorothiazide / triamterene) for High Blood Pressure: “I had a very bad reaction to Dyazide for high blood pressure. After 3 days, I was overwhelmed by disorientation, heart palpitations, muscle cramps in my feet and legs, dizziness, and nausea. Although I was drinking a great deal of water, I was found to be severely dehydrated with electrolyte imbalance.”

4 / 10
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Pamepie · Taken for 10 years or more July 24, 2014

Dyazide (hydrochlorothiazide / triamterene) for Edema: “I break a 50 mg tablet in half and take the half every other day. It really works and I find I need to increase my liquid intake particularly on the days I take the 1/2 tablet otherwise I tend to have some muscular cramping. This is especially true in leg muscles.”

9 / 10
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maxiybby1 May 26, 2016

For High Blood Pressure: “I was put on Triamterene HTCZ 37.5-25 mg. as a replacement for Lisinopril (coughing and throat closing up after 2 yrs. on med) I was put onTriamterene in January , blood pressure was good but felt nervouse at times, mood swings, constipated. March had blood work , my uric acid level was 10.1 High, my Bun was 10.1 High, had blood in my urine and fowel smelling urine. Was not feeling well. My blood work also stated " Moderately Reduced Kidney Function" This med is poison to the kidneys! March stopped Triamterene was put on Verapamil ER 120MG. Seems to be working o.k..i am very relaxed on this med which helps my pb as I am a nervouse anxiouse person which brings up my BP. New Lab reports are now good.”

1 / 10
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Anonymous September 12, 2009

Dyazide (hydrochlorothiazide / triamterene) for High Blood Pressure: “I am a 52 year female and have been on Dyazide for 10 days. I have had no side effects from the medication and edema in my leg has cleared up completely. I have also lost 12 pounds of water weight. Blood Pressure has improved, but still higher than it should be.”

9 / 10
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gsf March 27, 2011

For High Blood Pressure: “I have been using this medication successfully for several years. Lowered blood pressure and no side effects. This last month my prescription company switched manufacturer and I had a severe reaction to the drug. Please be careful if the pharmacy switches brands. The manufacturers are not all the same.”

7 / 10
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Tdepay · Taken for 5 to 10 years April 12, 2021

For High Blood Pressure: “This pill is great at first, but after taking the drug for six years, I began to develop one side effect and then I looked at all the other problems I had been experiencing and identified at least 20. All reported to my Dr who only offered other treatments or specialist that only addressed the symptoms and not the side effect. I experienced, severe nerve pain, nose bleeds, bloating, bad headaches, knee joint inflammation, limited mobility, vision loss, hair loss, rash, loss of thoughts, fatigue, irritability, constipation, etc and not all at the same time but over time. In conclusion this pill is a really no good for me and slowly works you into to pop a pill culture. Do not recommend, completely switched to homeopathic solutions and doing much better.”

1 / 10
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Ken B July 12, 2013

Maxzide (hydrochlorothiazide / triamterene) for High Blood Pressure: “I started using Maxzide 15 years ago and it reduced my blood pressure which was between 135 and 160 to less than 130. I am now 71 and another medicine has been added. But 15 years on side effects and all was well.”

9 / 10
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Emerald_86 · Taken for less than 1 month February 29, 2020

Dyazide (hydrochlorothiazide / triamterene) for High Blood Pressure: “I am a 47-year-old female who was recently diagnosed with high BP. My NP started me out on Losartan and I experienced terrible side effects. My mom suggested I take what she's taken for 23 years--Dyazide. I got that from Dr and have been taking Dyazide for 3 weeks and it is great! It has lowered my BP from around 140/90 to 115/65. Also NO side effects. It is a small, light green, oblong pill.”

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ElisabethC · Taken for 6 months to 1 year January 22, 2016

For Edema: “I have been on this medication for a few months now, for the second time. Both times I have developed severe headaches, dizziness, confusion, and nauseous. It takes off some water weight but I'm still fairly swollen and this time my blood pressure has increased. Just learned that it can affect blood sugar levels. I don't think I will be taking this medication again.”

1 / 10
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SoupBowl June 15, 2013

For High Blood Pressure: “It works, but I am constantly urinating and constipated. I lost five lbs within two days after starting this medication, but I feel that I am losing too much water. I am thirsty, but I avoid drinking water because of the constant urination. My mother has been on it for decades and was diagnosed with gout last year. Her specialist told her the hydrochlorothiazide/triamterene caused the gout. She is no longer on the medication, but still having gout flare-ups. I haven't taken it for about a week, and I decided to reduce my salt and reduced the amount of food I am eating since I am overweight. It has been working, but I am monitoring my blood pressure by taking readings every morning and evening. I'll see what the doctor says.”

5 / 10
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Lord Byron September 16, 2009

For High Blood Pressure: “My doctor prescribed Triamterene/HCTZ 37.5 once a day about 6 months ago. In the meantime I experienced severe silent migraine type symptoms (light-sensitivity, motion sensitivity, brain fog, irritability, not able to read or think clearly) which I have never had before. My doctor even did a brain MRI to try to find the cause but never thought of my medicines side effects. I quit this medicine on my own and immediately noticed no more headache symptoms! Have been off for 2 months now and no silent migraine instances have occurred.”

1 / 10
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Vertigo Girl · Taken for 5 to 10 years July 9, 2019

For Edema: “I’ve been taking this hydrochlorothiazide with triamterene for years as a diuretic with no issues until last month. The manufacturer changed and at my pharmacy and I do not believe it works the same. My Meniere’s symptoms haven’t been this bad since I started taking the different brand. I hoping another pharmacy has the prior manufacturers medicine because it worked well.”

7 / 10
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Anonymous December 16, 2008

For High Blood Pressure: “Have been taking this for about 2 months now. The first few weeks I was tired and kept getting back and leg cramps at night. My feet are cold a lot now, but my blood pressure is great, I'm no longer tired and I haven't had any cramps. It definitely took a few weeks to get used to, but it's worth it now.”

9 / 10
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Anonymous September 10, 2009

Dyazide (hydrochlorothiazide / triamterene) for High Blood Pressure: “I am 39 years old, my doctor prescribed this medicine to help lower my blood pressure. From the first day, it made me very nauseous to the point of vomiting. It also made me feel dizzy, lightheaded and short of breath. I stopped taking it after 4 days and felt better. My doctor is switching me to an ACE inhibitor instead....hoping it will be better than this one.”

2 / 10
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Worrysome December 11, 2015

For High Blood Pressure: “I was prescribed this back in March of this year for high BP. My doc told me to take 1/2 of the pill. I kept taking myself on and off it until finally my bp started doing waves from 107/86-135/96 making me sick. So then my doc said start taking the full pill. I guess it works ok keeping my bp at a reasonable level. I just haven't really given it a chance because, I'm afraid it will raise my blood sugar. I'm not a diabetic but, my mom and sister have it. I just don't want this drug triggering that in me, if I have the diabetic gene. Has anyone here had that side effect? It raising your blood sugar levels?”

4 / 10
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Daryl28 December 14, 2015

For High Blood Pressure: “So far so good, been taking it three days now.....been thirsty than usual, drinking lots of water, I've started exercising regularly daily. Some slight headaches, stomach cramp my second day on it. Some effect on sex moods, but not that bad. More energy for me, no drowsiness, some dizziness but not so much where its noticed. B/p good, feel laid back and calm.”

10 / 10
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Anonymous September 30, 2011

For High Blood Pressure: “This medicine was added because Atenolol alone was not controlling the borderline high blood pressure. I didn't have much side effects at first, but now I can't walk a block with getting very painful leg cramps. My doctor told me to quit taking it until he can run blood tests. I have been drinking lots of water, which was supposed to help with the cramping, but has not relieved it.”

5 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.