Glimepiride and Blood Sugar: What Users Say

• Bif...
• May 1, 2010

Glimepiride for Type 2 Diabetes "This medication works almost too well. When you start this medicine, be aware of what low blood sugar symptoms are. I have experienced several episodes of blood sugar down to 52. Heed the warning to carry glucose tablets with you at all times."

• Typ...
• Taken for 1 to 6 months
• August 12, 2013

For Type 2 Diabetes "After being on Janumet 50/1000 twice daily, my sugar never seemed to drop at all, running very high 200. A1c got over 12%. My GP added glimepiride 4mg twice daily with meals, and wow, what a difference. I've never had to worry about low blood sugar until now. My A1c after 2 months is now 7%, sugar runs around 90 in the mornings now. I couldn't be happier with this medication. Some have commented on eating right after you take this, and I agree. It will drop your sugar fast, be careful. I also keep glucose tabs in my car now just in case."

• Ins...
• Taken for 6 months to 1 year
• November 17, 2019

Glimepiride for Type 2 Diabetes "Amaryl was my second prescription, as Metformin had too many side effects for me. The medicine was alright, to be generous. I had a lot of trouble with low blood sugar when I was taking Amaryl. I couldn't go three hours without eating. I usually ended up binging on candy or fruit juice to try and drag it back up. I had a few really bad scares. My A1C wasn't that great, and any type of 'bad' food would completely destroy my sugar. It seemed like I couldn't find a middle ground. I was switched to another medicine when it became clear it wasn't working well enough."

• Ros...
• Taken for 6 months to 1 year
• July 19, 2022

For Type 2 Diabetes "Be very careful with this med! Took it for 6 months and it was working well, then started having seriously low blood sugars of 50-55. Reduced the dose, and it did not matter. Happened to me while on vacation, walking on the beach with no phone. I had a difficult time making it back to my family. For some reason, my body started reacting badly with super low sugars from it, even with a reduced dose. Scary drops from 190 to 50 in a few hours. I had to stop taking it. The doctor had no idea why it started happening. No change in my diet or exercise. These diabetic meds are all scary, except for Metformin."

• Mar...
• February 6, 2018

For Type 2 Diabetes "Medication makes my sugar go low below 70. I take it in the mid-afternoon because I don’t want it to do it at night. My sugar is spiking and dipping all day long. I feel like a zombie, and then the next day I feel like I have a hangover! I've been on it for 6 months, and I can’t do it anymore. I want my life back!"

• Joa...
• April 27, 2018

For Type 2 Diabetes "In taking this, my blood sugar went low and caused veins around my ankle to rupture, and this is the only med I take. Now my abdominal right side is hurting, which I assume is pancreas!"