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User Reviews for Glimepiride

Also known as: Amaryl

Condition Avg. Rating Reviews Compare
Diabetes, Type 2  
6.6
64 reviews 151 medications

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Glimepiride

Simonizr · Taken for 1 to 6 months April 9, 2021

For Diabetes, Type 2: “Gained 5 lbs after two months of use. Will not continue this medication. Getting fat and the other 100 side effects are not worth it.”

1 / 10
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mikeandmary20 · Taken for 1 to 2 years March 31, 2020

For Diabetes, Type 2: “I take two- 6.25 in the morning for the last year and am also on alogliptin 1 time a day and still can't get my blood sugars down below 160-180. I can't exercise except walking with walker because of neck surgery and bad back (three disc missing in lower back. L-1 to L- 4 is bone on bone) so the typical exercise I can't do i can't bend over. I watch my diet. (I used to weigh 300 now. I lost down to 180 ) I just can't understand I use to be on insulin when I was heavy but since I quit taking metformin and switch to alogliptin and gliapride my sugars can't get to 100 -130 anymore. Any ideas? I would have gave it a 10 if it would lower my sugars a little more. No interactions no side effects no problems at all with the other 12 medications so I have just that slight problem”

6 / 10
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Big B · Taken for less than 1 month January 28, 2020

For Diabetes, Type 2: “I went to the ER with an infected finger and found out I was type 2 diabetic. Blood glucose at 640 when tested. Spent 3 days in the hospital. Used insulin shots to bring it down then glimepride to maintain it. I've been home 2 days. Ist day morning test 119. 2nd day 88. The doctor told me if it drops under 70 to cut the pill in half. So far so good.”

10 / 10
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Almost Jake March 16, 2011

Amaryl (glimepiride) for Diabetes, Type 2: “Bif's comments are true. This medicine will drop your sugar levels quickly, but it works too well. Thirty minutes after taking 2mg, I can feel my sugar levels getting low. I don't have the shakes (meaning my sugar levels are in the low 60's), but I probably would in a matter of minutes. After eating breakfast, I must eat again about 2 hours later or I'll get the shakes. I must be conscious of my sugar levels for the first 4 hours after taking a dose. Overall, my fasting sugar level has dropped from 140 to 110, simply by taking 2mg each morning. However, I find I am gaining weight and overeating too.”

9 / 10
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Anonymous September 1, 2008

Amaryl (glimepiride) for Diabetes, Type 2: “After a year and a half of working hard at exercise and diet while taking Metformin and Actos I was not able to get my blood sugar down below 140 and it was more often between 170 and 200. I was changed to metformin and Amyril just this last weekend and after just two doses my sugars have been between 80 and 108, something I had started to lose hope could happen for me. I am so thrilled.”

10 / 10
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Skullkeeper June 27, 2013

Amaryl (glimepiride) for Diabetes, Type 2: “I have been taking it for 2 years now . It will drop your blood sugar levels quickly so you need to eat within 10 minutes of taking it . If I exercise alot that will further drop my blood sugar levels . Be careful at first . I take a soda in the car with me just in case or carry glucose tablets until you see how it affects you . You may need to eat more than you are use to .I have not had any side effects”

8 / 10
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JLauren1 · Taken for 1 to 6 months October 22, 2019

For Diabetes, Type 2: “I just began taking Glimepiride 2mg, recently (with Metformin) and I LOVE it. I have never seen my numbers so nice, in the normal range. It's working great. I woke up this morning and my BG was 97. This inspires me to really watch everything I eat; I watch every morsel. And now I gently exercise. So fun to see normalcy.”

10 / 10
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Anonymous · Taken for 10 years or more May 4, 2019

Amaryl (glimepiride) for Diabetes, Type 2: “My physician prescribed Amaryl 4 mg 19+ years ago. We went to 4mg twice daily after 8 1/2 years. Results have always been very good. Fasting blood glucose has averaged in the 90’s with a seldom reading over 110 or below 80. Eat right, exercise, rest and drink LOTS of water. About 2 hours after morning dose I usually need a snack. I always keep soft peppermint if needed. Very happy with Amaryl and the generic Glimepiride.”

10 / 10
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Ubermodele February 25, 2016

Amaryl (glimepiride) for Diabetes, Type 2: “I was on Lantus Solostar and Metformin twice daily max dosage. Sugar counts were still 300 and 200. I was so frustrated because the insulin and supplies are extremely expensive with my HSA plan. Basically, my problem did not improve and I was broke. I ran out of insulin and did not have the money to refill. My dr's apt was three weeks later. I explained my low funds situation and promised to fill the Rx as soon as I received my next pay check. She said "Let's try a cheaper option for you". I said "Woo hoo! Let's!". She prescribed Glimeperide. I took a half pill for days 1 and 2. No change. I took the entire pill days 3 & 4...better...but not much. I take two pills daily now, and I see IMPROVEMENT! WOO HOO!”

9 / 10
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Bif May 1, 2010

Amaryl (glimepiride) for Diabetes, Type 2: “This medication works almost too well. When you start this medicine be aware of what low blood sugar symptoms are. I have experienced several episodes of blood sugar down to 52. Heed the warning to carry glucose tablets with you at all times.”

9 / 10
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Type 2_fr_Fla · Taken for 1 to 6 months August 12, 2013

For Diabetes, Type 2: “After being on Janumet 50/1000 twice daily my sugar never seemed to drop at all, running very high 200 , A1c got over 12%, my GP added glimepride 4mg twice daily with meals and wow, what a difference. I've never had to worry about low blood sugar until now. My A1c after 2 months is now 7%, sugar runs around 90 in the mornings now. I couldn't be happier with this medication. Some have commented on eating right after you take this and I agree. It will drop your sugar fast, be careful. I also keep glucose tabs in my car now just in case.”

10 / 10
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Cinful May 31, 2014

For Diabetes, Type 2: “I've was taking Glimepiride for almost a year then a new Doctor changed me to Metformin. I see a difference between the two medications in my blood sugar level. I was doing better with the Glimepiride. My sugar levels were lower and my sugar level with Metformin are much higher. I'm going to ask to be put back on Glimepiride.”

10 / 10
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Titration worker · Taken for 1 to 6 months August 16, 2013

Amaryl (glimepiride) for Diabetes, Type 2: “After 3 months of 2mg four times a day, with no change in glucose levels my doctor and I sat down for a talk. When asked if there was a ceiling for the dosages he said we have plenty of room to adjust (there actually is no recorded max dose I could find in the literature). The typical patient uses about 4 mg four times a day. I have found that I have had to increase as much as 16mg four times a day to see adequate glucose changes. It's ease of use and small size makes it easier to take than some, but I have yet to find it's stable dosage for ME.”

7 / 10
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DonRondel · Taken for 1 to 6 months December 4, 2019

For Diabetes, Type 2: “Walgreens filled my Rx renewal with a different glimepiride. The pill was nothing like previous glimepiride pills so I looked it up on line. I found the new pill is made off shore. Walgreens never advised this change so I'm going back to the pharmacy tomorrow to request they take these back and give me one made in the USA Also read the manufacturer of this pill had a problem getting its Indian factory approved by the FDA in 2017. Why is Walgreens selling such suspect drugs? I know ... they're cheaper for them. PLUS the Rx was for 180 but they only gave me 80 pills. I'm not enamored with Walgreens any longer.”

3 / 10
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cs6338 · Taken for 10 years or more April 28, 2016

For Diabetes, Type 2: “This drug was perfect for me. Was on it for 15 years and A1C was down to 5.8. Never had any problems. New doctor comes into the group and puts me on januvia which I cannot tolerate and has driven A1C and fasting levels up higher than ever. Trying to get back on glimepiride.”

10 / 10
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Bob T March 28, 2011

Amaryl (glimepiride) for Diabetes, Type 2: “This is a preliminary assessment after one month on Amaryl. I have always had an active lifestyle, but over the last two years have been disappointed not to be able to maintain an average morning blood sugar reading much below 140 since being diagnosed with Type 2 diabetes. Unlike most reviewers, I did not see an immediate reduction in blood sugar level until the last week, when my average dropped from the high 130s to five straight days between 101 and 108. This drop also corresponded to an extremely active week, tennis six straight days, bowling once and jogging a three-mile course twice. Appetite is great, so must watch weight. No adverse effects so far, even with almost daily use of Aleve as well. Will report back after longer usage.”

10 / 10
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Askpastor1 · Taken for less than 1 month July 20, 2016

For Diabetes, Type 2: “I take glimepiride with metformin. The morning I took my fist dose, my blood sugar was 169. Two hours later, it was down to 141, and two hours after that it was down to 107. The next morning, my blood was 120 or so. I reasoned that if I took it again, and it brought my blood sugar down 60 points, it would be too low. So I didn't take it. For the next five days, I took only my metformin because my levels were in a very reasonable range. On the fifth or sixth day, my level went above 150. I took Glimeperide and for the next 5 days, my sugar levels were low enough not only to not take the Glimeperide, but also to cut back on my metformin.”

10 / 10
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Kandaygurl November 26, 2016

For Diabetes, Type 2: “I have been on several non insulin drugs and nothing lowered my blood sugar untiI started glimipiride. At first I took one pill in the morning and one at dinner. I was still eating a large dinner and eating junk food. My sugar levels would go down but were,all over the place. When my A1C increased significantly in three months I knew I had to make a change. I now take Double the dose of glimipiride in the evening. However when I got serious about my diabetes, I changed the way I eat. Smaller meals more often is best on this medication in order to not have dips and spikes. A good breakfast and a mid morning snack works well. A moderate lunch with an afternoon snack makes good sense. A low carb-high lean protein dinner. The med works well”

7 / 10
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CCinTN · Taken for less than 1 month May 11, 2019

For Diabetes, Type 2: “My doctor switched me to glimepiride because Metformin was causing me problems. I've been taking two per day for about 3 weeks and it isn't lowering my blood sugar at all. It hasn't been below 224 since I started taking glimepiride. This morning my fasting count was 255, I ate an omelette with lots of vegetables and cubes of ham, then 2 hours after taking my meds, my blood sugar level was 268. I had nothing to drink but water.”

1 / 10
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Ginny · Taken for 1 to 6 months August 24, 2019

For Diabetes, Type 2: “I was taking Januvia and Invokana but it wasn't quite enough so my doctor added glimepiride. I started taking it 3 months ago and it really worked! My A1C dropped to 6.7 and I average 120-130 blood sugar. My blood sugar bottomed out a few times since starting it but I just have to plan snacks and eat properly. My only complaint is I gained weight since starting it and I'm hungry more often.”

9 / 10
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lj · Taken for 1 to 2 years September 4, 2019

For Diabetes, Type 2: “I did not like the diarrhea I had with Metformin so Dr. put me a glimepiride. My A1C is around 7, but that is not the problem. The constant lows and weakness are getting unbearable. No matter what kind of breakfast I have or if I take a whole pill due to bigger breakfast or half a pill with a small breakfast, by 4:30 or later I have crashed to 70 and below. I have even had a 57. and once a 50 with a scary dizzy spell. Once I walk the dogs, do shopping or anything I drop like a rock and feel almost to weak to fix something to eat to bring my BS up. I can’t always be eating snacks, I’m out and about and overweight enough to not want eat just to keep from going too low. I hate this medication and next Dr. appointment guess I’ll have to try Metformin again. I feel this pill is dangerous because of my everyday low readings.”

3 / 10
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cathyr46 March 25, 2012

Amaryl (glimepiride) for Diabetes, Type 2: “I have been taking Amaryl for 3 weeks and it has lowered my blood sugars 70 points. I do have stomach problems since taking this medication, I do find that I have to watch my sugars as after about 2 hours my sugar level drops.”

7 / 10
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Insomniac Too · Taken for 6 months to 1 year November 17, 2019

Amaryl (glimepiride) for Diabetes, Type 2: “Amaryl was my second prescription, as Metformin had too many side effects for me. The medicine was alright, to be generous. I had a lot of trouble with low blood sugar when I was taking Amaryl. I couldn't go three hours without eating. I usually ended up binging on candy or fruit juice to try and drag it back up. I had a few really bad scares. My A1C wasn't that great and any type of "bad" food would completely destroy my sugar. It seemed like I couldn't find a middle ground. I was switched to another medicine when it became clear it wasn't working well enough.”

4 / 10
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Frustrated · Taken for 1 to 6 months May 4, 2019

For Diabetes, Type 2: “Just started this medicine after Junevia made me feel like I had Lyme disease. Have been on Glimepiride 1 mg once a day for a month. Works great on lowering sugar levels. My stomach and intestines blow out like a balloon after I eat no mater what it is. Make me weepy, moody, and have gained 7 lbs in one month. Not going to live like this!”

8 / 10
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rdh557 August 2, 2015

For Diabetes, Type 2: “I havae been on this drug for 6 months, still having problems maintaining sugar levels. My sugar has dropped to 44, 67,70, so I eat something before bed time. Some mornings it is at 130,160 or as high as 235. It seems as though the pill will bring levels down very quickly causing me to eat late to get them up again, only to have them rebound to high by morning.”

8 / 10
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Kate Lynn February 11, 2016

For Diabetes, Type 2: “My A1C hit 7.2, and my doctor put me on glimepiride, 1 mg at my largest meal (usually breakfast). My BS hit 73; fortunately, I now carry glucose tablets with me. It's working well for me and, so far, no side effects. In three weeks, A1C went from 7.2 to 6.2 (estimated). I will see doctor next week for professional evaluation. I like this medication.”

10 / 10
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cmin · Taken for 2 to 5 years August 6, 2014

For Diabetes, Type 2: “Diabetic for 7 years. Started with Metformin only. Then added Starlix with meals. Small improvement with post-prandials. Exchanged the Starlix with glimepiride. Have been on glimepiride for 2 and a half years with meals. Does not prevent my spikes but does pull them down within a short time. The sudden drop makes me feel low when I am just "dropping" FAST into the normal range. The problem is the time it remains in effect will cause me to be low (50;s) during the night while sleeping if I take with last meal of day. Without it, I skyrocket after eating and slowly come down. My doctor is taking me off of glimepiride because of the lows while sleeping and will put me on another med. My A1C's have been climbing over the past year.”

8 / 10
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blue jean queen · Taken for less than 1 month May 12, 2015

For Diabetes, Type 2: “I was on Glyburide and Januvia for a long time. Then my insurance company decided that I had to take Glimepiride instead of Glyburide because it works better. I have noticed a difference already after just a few weeks. My blood sugar readings are much lower than they were on Glyburide.”

10 / 10
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This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.