Fremanezumab and Fatigue: What Users Say (Page 2)

• Ruk...
• Taken for 1 to 2 years
• December 31, 2024

Fremanezumab for Migraine Prevention "I’ve been taking Ajovy for 2 years now, and the migraines are 80% less. However, some of the side effects I have (even though they are not listed and medical professionals will probably not even acknowledge them) are dizziness, unexplained weight gain, high cholesterol, and fatigue."

• Ter...
• Taken for 1 to 6 months
• April 20, 2023

Fremanezumab for Migraine Prevention "I’ve had 2 full months on Ajovy now. My headaches have been reduced from 20 per month to 11 per month! While I still have some additional days with prodrome symptoms and no headache, this has also reduced significantly. I can concentrate (less brain fog) for longer periods now, have a little more energy, and want to take part in my own life for the first time in more than 2 decades!! I experienced slight site bruising from one injection, and fatigue and body pain for a couple of days after both. But having FM/CFS makes it hard to tell if those symptoms are side effects or not. I am cautiously optimistic that this will be a long-term solution for me and am very thankful for Ajovy’s effectiveness. Way to go, Teva!"

• Hea...
• Taken for 1 to 6 months
• September 5, 2021

Fremanezumab for Migraine Prevention "Ajovy worked okay for migraines, but took 3 months to kick in. Unfortunately, it also caused chest pain, shortness of breath, extreme fatigue, anxiety, and heartburn. It shouldn't be surprising that it causes so many issues, given all the things CGRP does in your body, but it's so new that most neurologists seem to believe it has only mild (or even no) side effects."

• See...
• Taken for 1 to 6 months
• October 2, 2021

Fremanezumab for Migraine Prevention "Oh, how I wish I could come here first before agreeing to try Ajovy! Started taking it in Feb. '21. First month, no migraines/no issues; however, in subsequent months, I started getting more migraines and more often than when I was on my previous preventative (Topamax). My doctor said to 'give it time,' citing very few known side effects. I definitely got the injection site redness, but what I didn't realize right away was that everything else I began to experience was also related to Ajovy (I just didn't realize it right away). It seemed as if I gained weight at a rapid pace overnight each month without changing a thing. Every bone and joint in my body ached, I had zero energy, and all I wanted to do was sleep all the time. I had no idea what was going on and thought, like many others here, that I was crazy. I took my last and final injection in August and am slowly (slowly) starting to see these awful side effects fade."

• Aja...
• Taken for 1 to 6 months
• February 16, 2021

Fremanezumab for Migraine Prevention "Absolutely brilliant, one migraine in a month compared to three a week for thirty years. I've tried everything, and nothing works except for sumatriptan, but that makes me very drowsy. But I'm getting very concerned about the side effects of Ajovy: swollen legs, constipation, lower back pain, anxiety, and fatigue - it's only been three months. I am hoping it will get better, as for me, this is a wonder drug."

• Nat...
• April 2, 2022

Fremanezumab for Migraine Prevention "My experience has not been the best. This is my first injection and I am having a rough time with fatigue and mental function. I am losing words, all of a sudden, my hunger has increased. This is like taking Topamax."

• Anonymous
• Taken for less than 1 month
• February 9, 2022

Fremanezumab for Migraine Prevention "I used this at the beginning of last year and did seem to help. My prescription was not refilled after 4 injections. I developed COVID in August 2021. I restarted the injections on February 1, 2022. After my first dose, I have felt chest pains, neck pain, severe fatigue, shaking of my hands severely, and throwing up blood. Needless to say, I will not be taking it again until more research has been done with reactions to COVID."

• JK1...
• Taken for 6 months to 1 year
• September 29, 2021

Fremanezumab for Migraine Prevention "I've been on Ajovy for about 6 months. It was like a miracle. I'm not burning all of my PTO on migraines anymore. Not sure if this is related, but a couple of weeks ago, I aggressively used a muscle roller over my Ajovy injection site (over my right quad) for a few days. Next thing I know, I am in so much pain for days and days. My quad starts to spasm constantly when I walk, this terrible gripping and twisting sensation every few seconds. My back hurt. I also got a very bad case of cutaneous allodynia just over my right quad and IT band, which I’d never had before. Then, 2 days ago, I got cutaneous allodynia from my neck down to my knees. I felt cold and fatigued, and everything hurt, but no other symptoms. It's mostly gone now, but it was completely debilitating. For the last 3-4 months, I also started having very brief bouts of dizziness that last between a few seconds and maybe 5 minutes. That part is manageable. It only happens once every few days."

• PMG...
• Taken for 1 to 6 months
• October 31, 2021

Fremanezumab for Migraine Prevention "I have been suffering from migraine for 30 years. Somehow, I was able to manage, but the last 3 years it got worse. I tried Topamax. Very bad experience. I was on a beta blocker. Bad experience. Nortriptyline actually worked well for me. It cut my headaches by a lot. I had maybe 1 headache a week. But some side effects I could not tolerate. Then I switched to Ajovy. My 5 injections were not bad, but my 6th I started experiencing very bad side effects like: heart palpitations, anxiety, muscle cramps, fatigue, dizziness, off-balance, and constant pressure on top of my head. I notified my doctor, but he said that he was not aware of symptoms like that, so it is only one way to find out. I decided to stop. My last injection was on October 16. Reading reviews here, I noticed that people have similar symptoms and I am not crazy. This is a new medication on the market and there is not enough data on possible side effects. I have to admit that it did help with migraines."

• pau...
• Taken for 6 months to 1 year
• October 1, 2021

For Migraine Prevention "I have been using fremanezumab for 7 months. I was getting 12 to 15 migraines a month, and they had a massive impact on my life. The first 4 months of using this injection, I only had 3 or 4 a month, however, now, a couple of months, I have found I have been getting more. I also found the injections used to sting like crazy, but the last couple I've hardly felt. Strangely, these are the months they haven't been as effective. When my consultant rang after the first month and asked if I had side effects, I said no, but now I wonder. I too have had weight gain, very restless, and not sleeping, also been getting mild chest pain and extreme exhaustion. I recently went for a heart scan because of my symptoms. I had never put any of this down to fremanezumab. I've been to doctors several times, but they have never said it could be related. I really don't know what to do now."

• Mig...
• Taken for less than 1 month
• December 26, 2019

Fremanezumab for Migraine Prevention "Intense body pain and fatigue. It lasts 1-5 months, apparently. Migraines are gone."