Fremanezumab Side Effects
Applies to fremanezumab: subcutaneous solution.
Precautions
It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.
This medicine may cause serious allergic reactions, which can be life-threatening and require immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after using this medicine.
Serious side effects of fremanezumab
Along with its needed effects, fremanezumab may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking fremanezumab:
More common side effects
- fast heartbeat
- fever
- hives, itching, skin rash
- hoarseness
- irritation
- joint pain, stiffness, or swelling
- redness of the skin
- swelling of the eyelids, face, lips, hands, or feet
- tightness in the chest
- troubled breathing or swallowing
Other side effects of fremanezumab
Some side effects of fremanezumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common side effects
- bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
For healthcare professionals
Applies to fremanezumab: subcutaneous solution.
General adverse events
The most commonly reported adverse reaction during clinical trials was injection site reactions.[Ref]
Local
- Very common (10% or more): Injection site reactions (up to 45%)[Ref]
Injection site reactions included injection site pain, induration, erythema, and pruritus.[Ref]
Hypersensitivity
- Uncommon (0.1% to 1%): Hypersensitivity reactions
- Postmarketing reports: Anaphylaxis, angioedema
Immunologic
- Common (1% to 10%): Anti-Drug-Antibodies[Ref]
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References
1. EMEA. European Medicines Agency (2007) EPARs. European Union Public Assessment Reports. http://www.ema.europa.eu/ema/index.jsp?curl=pages/includes/medicines/medicines_landingpage.jsp&mid
2. (2018) "Product Information. Ajovy (fremanezumab)." Nephroceuticals
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Further information
Fremanezumab side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.
