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Fexofenadine / pseudoephedrine and Insomnia: What Users Say

Brand names: Allegra-D 12 Hour, Allegra-D 24 Hour, Allegra-D 12 Hour Allergy & Congestion, Allegra-D 24 Hour Allergy & Congestion

Insomnia: mentioned by 17 users (26.6%)

Based on user experiences from 64 Fexofenadine / pseudoephedrine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

insomnia 26.6%
dry mouth 15.6%
anxiety 9.4%
dizziness 9.4%
nausea 9.4%
headaches 7.8%
cough 6.3%
depression 6.3%
loss of appetite 4.7%

Reviews for Fexofenadine / pseudoephedrine

Showing 17 reviews tagged with "insomnia". Clear filters to view all 64 reviews.
Commonly mentioned side effects
  • Ste...
  • May 13, 2015

Fexofenadine / pseudoephedrine for Allergic Rhinitis "This medication is NOT recommended! I have severe allergies to the spring weather, and since nothing else was working for me, I decided to try this. At first, it was like magic, my allergies went away, no itchy eyes, no sore throat, I felt great! The side effects really hurt me, though. It was about two days after taking the medication that I suffered a 24-hour migraine along with flu-like symptoms, high fever, rashes, dizziness, confusion, racing heart, chills, anxiety, nausea, dry mouth, sleep problems, loss of appetite, and ringing in my ears. It has been the worst two days of my life thanks to this medication."

2 / 10
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  • C a...
  • October 13, 2009

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I have chronic rhinitis. I was very ill last year, and my immune system hasn't been the same since. My immune system now reacts to everything around me, i.e., I'm allergic to all of my surroundings: dust, pollen, etc. Instead of the typical runny nose and sneezing, the inner membrane of my nose would swell almost completely shut. I was miserable. Accompanied by a nasal spray, Allegra-D was the best thing that's ever been prescribed to me! Although at first, I suffered severe insomnia, the side effects became milder with time."

10 / 10
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28 Report
  • Anonymous
  • Taken for less than 1 month
  • September 15, 2013

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I've tried other allergy medications, but Allegra-D is the only one that works. I used to get constant post-nasal drip and have to clear my throat all the time. On this medication, I feel amazing. It does, however, cause insomnia and bad dry mouth. It also makes it so I don't get a full erection. So do I feel better and not have sex, or what?"

9 / 10
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27 Report
  • Ano...
  • May 26, 2015

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I was prescribed this medication several years ago for allergies. I was told to take it twice a day. It was effective; however, it did cause insomnia to the point the doctor instructed me to take it once a day. It also gave me headaches the first few days taking it. Other than that, it was highly effective."

7 / 10
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13 Report
  • gan...
  • April 5, 2009

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I have severe pollen allergies, and Allegra-D was the best medicine I ever took, until I could not sleep. It causes insomnia in me, so the trade-off is insomnia versus feeling miserable 24/7. It took 2-3 days before I first received relief. Then there was a huge difference."

9 / 10
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16 Report

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  • sle...
  • Taken for less than 1 month
  • August 29, 2014

For Allergic Rhinitis "Took it around 6:30 am before leaving for work. Experienced terrible insomnia even though I took it early in the morning. Couldn't stay asleep more than three or four hours. Awful stomach pain and loss of appetite. Some itching. Weakness and dizziness when standing too quickly. Dry mouth, so I'm constantly drinking water. Unfortunately, the other OTC medicines didn't work as well as this product. I'm in a lose-lose situation."

9 / 10
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11 Report
  • She...
  • July 10, 2009

Fexofenadine / pseudoephedrine for Allergic Rhinitis "Allegra D is the best medicine for my allergies, and I've taken just about every over-the-counter medicine. I have terrible hay fever, and I'm allergic to almost all grasses, trees, and pollen in my region (Midwest - Illinois). My allergist suggested that I move to Arizona. Unlike Allegra D 12-hour, I'm having trouble with side effects: insomnia, nausea, heartburn, cramping. The stomach-related effects are beginning to taper off, but the insomnia isn't."

9 / 10
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17 Report
  • Ano...
  • Taken for less than 1 month
  • April 13, 2019

Fexofenadine / pseudoephedrine "I'll never take this again. I took this twice. Decrease in allergies, but I would rather deal with allergies than the horrible side effects. This drug made me an emotional wreck both times, extreme insomnia, and had vivid dark, self-harming thoughts, even though I am a very happy person. Also, I was very nauseous. I can't believe this stuff is available over the counter."

2 / 10
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  • Wal...
  • Taken for 2 to 5 years
  • November 16, 2016

For Allergic Rhinitis "OMG, I have been on fexofenadine for over two years, and for at least as long, I thought my insomnia was perimenopausal, but since I have ceased taking it, my sleep has come back. Call it coincidence, but this has aged me, and I will never fully be able to repair the damage it has done to me through lack of sleep. I will just use loratadine in the future, no more bad nights for me."

5 / 10
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3 Report
  • NPF...
  • Taken for less than 1 month
  • April 26, 2016

For Allergic Rhinitis "I have what I'll deem 'allergy attacks,' primarily to tree pollen. I tried Allegra for the first time, and it worked on my allergies. I took it at 3 PM Sunday and was better that evening. I took another pill Monday at 7 AM and a third Monday at 7 PM (instructions read once every 12 hours). Monday night, I went to bed at 10 PM, woke up at 12 midnight, and was unable to fall back asleep again. I was exhausted, eyes gritty, but could not fall asleep no matter what. I will try a lower dose (once every 24 hours), but not sleeping isn't worth curing the allergy."

3 / 10
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  • Ill...
  • August 29, 2009

For Allergic Rhinitis "Allegra works really well for hay fever. I don't like the side effects, though. I haven't experienced insomnia, but I feel super hot (body temperature) when I take it. I also feel thirsty as well. I do suggest taking it on your day off to see how your body acts on it."

7 / 10
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1 Report
  • Anonymous
  • March 10, 2009

Fexofenadine / pseudoephedrine for Allergic Rhinitis "Efficient for allergies, but bad side effects. I experienced many of them: ringing in my ears, insomnia, unusual behavior, anxiety, unable to concentrate, itchy skin, and a couple more."

3 / 10
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24 Report
  • msd...
  • March 25, 2009

Fexofenadine / pseudoephedrine for Allergic Rhinitis "Good for hay fever symptoms, but caused insomnia."

4 / 10
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8 Report
  • Kan...
  • Taken for 1 to 6 months
  • July 9, 2018

Fexofenadine / pseudoephedrine for Allergic Rhinitis "I only take this in my extreme cases where my congestion gets so bad I can't breathe; I never take this daily. Within an hour, I feel better. It does do a bit of insomnia, but that's usual for me."

9 / 10
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3 Report
  • MoJ...
  • August 9, 2014

For Allergic Rhinitis "I took it for a cold. It completely eliminated nasal congestion. HOWEVER, it gave me terrible insomnia! Use only if absolutely necessary."

7 / 10
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4 Report
  • Anonymous
  • Taken for less than 1 month
  • September 10, 2012

Fexofenadine / pseudoephedrine for Allergic Rhinitis "This is the only medicine that works for my allergies. I get horrible allergies, so miserable I can't breathe. This medication helps me a lot, but I have trouble sleeping."

9 / 10
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5 Report
  • Swe...
  • July 14, 2009

For Allergic Rhinitis "I've tried many over-the-counter medicines for allergies. None come even close to working as well as Allegra-D. I also have suffered no side effects, including insomnia."

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.