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Fexofenadine / pseudoephedrine and Depression: What Users Say

Brand names: Allegra-D 12 Hour, Allegra-D 24 Hour, Allegra-D 12 Hour Allergy & Congestion, Allegra-D 24 Hour Allergy & Congestion

Depression: mentioned by 4 users (6.3%)

Based on user experiences from 64 Fexofenadine / pseudoephedrine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

insomnia 26.6%
dry mouth 15.6%
anxiety 9.4%
dizziness 9.4%
nausea 9.4%
headaches 7.8%
cough 6.3%
depression 6.3%
loss of appetite 4.7%

Reviews for Fexofenadine / pseudoephedrine

Showing 4 reviews tagged with "depression". Clear filters to view all 64 reviews.
Commonly mentioned side effects
  • Che...
  • Taken for less than 1 month
  • March 7, 2018

Fexofenadine / pseudoephedrine for Allergic Rhinitis "This medicine works great for allergies. However, day five into taking it, I’m experiencing major depression/personality changes. I don’t feel like myself at all, and there’s nothing else in my life that would contribute to this. My personality feels extremely subdued, I’m withdrawn, don’t care about anything or anyone, and negative self-talk has significantly increased... this is not who I am! I’ll be stopping this medication tomorrow."

2 / 10
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12 Report
  • Ano...
  • Taken for less than 1 month
  • November 7, 2019

Fexofenadine / pseudoephedrine for Allergic Rhinitis "Do NOT take this medicine. It should be illegal. I took it for 3 days, and all 3 days I felt nauseous, dizzy, unmotivated, and depressed. The worst part is I haven’t slept more than 2-3 hours a night. This medication will disrupt your life. I usually take Zyrtec D but decided to try Allegra out - my allergies have gotten exponentially worse on it. I have had severe sinus pressure, a cough, and headaches in addition to all the other symptoms."

1 / 10
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10 Report
  • Dan...
  • Taken for less than 1 month
  • September 4, 2021

Fexofenadine / pseudoephedrine for Allergic Rhinitis "Lately, I have been so confused and unable to focus in school. This began shortly after I started attending my university. I've been more irritable, I don't like anybody anymore. I've been less motivated, more depressed, socially withdrawn, have had more problems in my family/friend relationships, and I don't do things that I used to enjoy. This all began after I started taking this medication—I was doing fine in school and was motivated to succeed until I began taking Allegra-D. I wouldn't recommend this drug to anybody."

1 / 10
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4 Report
  • Not...
  • Taken for less than 1 month
  • November 28, 2019

For Allergic Rhinitis "I've been taking Fexet D for the past two days, and I've been absolutely miserable. I have acute sinusitis, and this medicine does help with the congestion, however, it also makes me extremely nauseous, irritable, and depressed. It also makes me sneeze excessively and makes me extremely light-headed. Will not be taking it again anytime soon unless I absolutely HAVE to."

2 / 10
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2 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.