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Loestrin 21 1/20 and Irritability: What Users Say

Irritability: mentioned by 5 users (13.2%)

Based on user experiences from 38 Loestrin 21 1/20 reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

acne 36.8%
mood swings 26.3%
cramps 21.1%
bleeding 18.4%
dizziness 18.4%
headaches 15.8%
irritability 13.2%
weight gain 13.2%
depression 10.5%
anxiety 7.9%

Reviews for Loestrin 21 1/20

  • Loe...
  • September 14, 2015

For Birth Control "After only taking this pill for 14 days, I made the decision to discontinue it. For me, this medication makes me miserable. The problems I experienced were: major anxiety, irritability and agitation; nausea; one episode of extreme dizziness and headache to the point I wondered if I was having a stroke; breast tenderness; fluid retention; fatigue; strange dryness around my gums; abdominal cramps; and a noticeable change in my bowel movements; an absolute loss of libido. It is hard to believe that a little BC pill can wreck your physical and emotional well-being in less than 14 days. I will never take this pill again!"

2 / 10
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  • Loe...
  • September 14, 2015

For Birth Control "After only taking this pill for 14 days, I made the decision to discontinue it. For me, this medication makes me miserable. The problems I experienced were: major anxiety, irritability and agitation; nausea; one episode of extreme dizziness and headache to the point I wondered if I was having a stroke; breast tenderness; fluid retention; fatigue; strange dryness around my gums; abdominal cramps; and a noticeable change in my bowel movements; an absolute loss of libido. It is hard to believe that a little BC pill can wreck your physical and emotional well-being in less than 14 days. I will never take this pill again!"

2 / 10
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  • Syd...
  • Taken for 1 to 6 months
  • March 21, 2021

For Birth Control "Worst BC I’ve ever taken. I had previously been on Tri-Sprintec for years, so long I lost count. Started having breakthrough bleeding on that, so I was switched to this. About two weeks in, I started becoming irritable. Didn’t really click with me initially, but over the past two months, I’ve continued to be on it, my mood has become unbearable. I’m usually a chill, happy person. This makes me feel psychotic. I am raging constantly. For absolutely no reason. The thought of sex annoys me. Everything does. It’s made my migraine headaches worse. I have one at least every other day. I’ve decided to come off of it and go back to my previous BC. I’d rather deal with the bleeding."

1 / 10
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2 Report
  • Ell...
  • January 13, 2020

For Birth Control "The devil in disguise. I never experienced anxiety problems before taking this joke of a pill, and soon I found myself taking sick days because of extreme panic attacks. It caused very unpredictable mood swings, made me very irritable and irrational. My boyfriend even compared my behavior to the Joker's - had the highest highs and the lowest lows. The way it made me act was scary to me and those around me. I felt possessed, and I had no control over my emotions. I'm usually a chill person, and this pill made me angry and upset at things which I wouldn't typically bat an eyelid at. The first month was actually okay, and I thought it would stay that way. It got much worse after a month. I was led to believe symptoms would improve after 3 months, but they only continued to get more and more severe. Worst 4 months of my life taking this pill. Writing this to prevent another woman from experiencing what I did - I wouldn't wish this experience on my worst enemy. AVOID AT ALL COSTS."

1 / 10
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  • Anonymous
  • November 1, 2010

For Birth Control "On for one month, my typically high-patience and calm mood changed to constant irrational mood swings, irritability, and mild depression."

1 / 10
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2 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.