Skip to main content

Loestrin 21 1/20 and Depression: What Users Say

Depression: mentioned by 4 users (10.5%)

Based on user experiences from 38 Loestrin 21 1/20 reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

acne 36.8%
mood swings 26.3%
cramps 21.1%
bleeding 18.4%
dizziness 18.4%
headaches 15.8%
irritability 13.2%
weight gain 13.2%
depression 10.5%
anxiety 7.9%

Reviews for Loestrin 21 1/20

  • Vic...
  • April 25, 2019

For Birth Control "This Loestrin pill is terrible! The first week of taking it caused me to have unbelievable dizziness and nausea to a point where I thought I was going to collapse! I became snappy, irritated, and depressed every single day, and I would have the odd spot that was very sore on my chin, forehead, and cheeks that took longer to heal than when I wasn’t on this pill. Strange pinprick spots that were very sore appeared on my fingers and toes. After visiting the doctor twice, they could only put it down to this pill. After another 6 months of taking this pill, I suddenly had migraines, which landed me in the doctor’s twice and a hospital visit, as I thought I was having a stroke! I have now discontinued this pill due to this, and I am now happy, head pain-free, and feel absolutely amazing! I should have stopped taking this pill a long time ago! Please be careful if you’re prescribed this pill and stop immediately if you have any sickness or dizziness, as that’s just the start of it all!"

1 / 10
Was this helpful?YesNo
4 Report
  • Not...
  • Taken for 1 to 6 months
  • August 1, 2019

For Birth Control "I was on this birth control pill for about 4 months, and it was just not for me. I had terrible mood swings, which were affecting my relationship, started having dark thoughts and was sinking into depression. I lost my appetite completely. It may work for some, but I guess just not for me."

2 / 10
Was this helpful?YesNo
2 Report
  • Can...
  • November 9, 2019

For Birth Control "I went on this pill after trying Reclipsen/Apri, which made me unbelievably sad and had awful mood swings. This pill, so far, has been great except that I have breakthrough bleeding all the time, even taking the pill on the DOT every day. I believe it is just my body getting used to the low dose, but it is awful. I have yet to notice any awful depression symptoms, though!"

5 / 10
Was this helpful?YesNo
1 Report
  • Anonymous
  • November 1, 2010

For Birth Control "On for one month, my typically high-patience and calm mood changed to constant irrational mood swings, irritability, and mild depression."

1 / 10
Was this helpful?YesNo
2 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.