Dotti for Postmenopausal Symptoms User Reviews

• Pit...
• Taken for less than 1 month
• April 11, 2023

"This experience has been extremely unpleasant. All of my cardiac, vaginal, urinary, sleep, agitation, and hot flash symptoms have returned. I strongly believe that this medication should not have been approved by the FDA for use in the United States. The prescribing information says that 'No studies were conducted,' yet the medication uses a different adhesive to hold the micronized estrogen and has smaller dimensions than Vivelle Dot. As a retired pharmacist, I am angry that I am having to go through this situation again. It is frustrating that despite the ratio of surface area, mg's in the 'glue,' and dose being a 1:1 relationship, this medication was still allowed on the market with all of these differences. I have already made a formal complaint to the FDA, and I encourage others to do the same. Please call 1-800-FDA-1088 or report online at accessdata.fda.gov/scripts/medwatch/. The struggle is real, and action needs to be taken."

• KLS...
• Taken for less than 1 month
• May 24, 2023

"Dotti is horrible! Don’t let your pharmacy give you this junk. Rite Aid started substituting Dotti for my normal twice-a-week Sandoz patches, and within a couple of weeks, I was back to urinary urgency and incontinence - my main reason for starting HRT. Everything had been going wonderfully with Sandoz. For what it’s worth, I checked the labels on both Sandoz and Dotti 0.05, and they actually are NOT equivalent in the amount of estrogen (estradiol) they provide! Sandoz provides .78 mg of estradiol per patch, Dotti provides .627 mg per patch. How can they be classified as equivalent?! Total rip-off, and the FDA should do something about this."

• DOT...
• Taken for less than 1 month
• October 28, 2022

"My plan stopped paying for the brand Vivelle Dot, and I was switched to Dotti. The round patch seemed nice, but OMG, major vasomotor symptoms, which I hadn't experienced in years. Wish the FDA would have more oversight on the quality of these offshore generic products. All generics are not equal!!!"

• Mar...
• Taken for 6 months to 1 year
• April 7, 2025

"These comments just show you that all bodies are different! I was swapped from 0.025 mcg Dotti to Sandoz and do horrible on Sandoz. Rash, estrogen-type dumping symptoms. But more than this, whether you prefer Dotti or Sandoz, it's such BS that women have to constantly be given generics or swapped to different generics due to insurance BS and deal with all the new absorption issues with each new 'adhesive matrix.' After all, we pay for insurance ($869/month in my case), we should have better options or we should be able to CHOOSE our generic preference. Oh, right, wait, 'Women get to CHOOSE.' Forgot we live in America. Yeah, not going to happen."

• Iha...
• Taken for 1 to 6 months
• May 14, 2021

"At the start of this year, my pharmacy began sending me Dotti patches instead of the ones I had been using. Gradually, my symptoms reappeared: unprovoked bouts of anger and irritability, mood instability, hair loss, and extreme skin dryness. Then came bouts of darker depression. I wondered if it was the change in patch manufacturer, but brushed it off. Then came the hot flashes and the night sweats; these progressed to full-on night drenching. Finally, I knew this wasn’t normal, began researching, and that led me to this review site. I am so grateful other women are reporting this because I was starting to think I was crazy! Thank you to the women who took the time to post experiences here. I just picked up patches from my old manufacturer, thankfully, and slapped one on. For years, the other manufacturer gave me relief. I’m so happy to be back on that. Dotti was completely ineffective for me."

• Not...
• Taken for less than 1 month
• February 8, 2023

"I was given Dotti as I could not get my usual medication. Within a week, I was feeling depressed, was feeling hot all the time, and only getting 4 hours of sleep, and I have had issues with rage and have been isolating myself. This drug is horrible. Thank you, everyone, for having left reviews."

• Lul...
• October 1, 2020

"The worse estradiol patch is the Dotti and the Mylan brand. What is going on! Why the sudden shortages in Vivelle dot? I've been on for 20 years. Don't they understand their versions are not working for us? We are trying to tell the manufacturers, but no... no one is taking our advice. I really don't like being at the mercy of them and doctors."

• Cat...
• Taken for 1 to 6 months
• December 1, 2022

"I definitely can tell these patches are not working. I own a pharmacy and can tell you that the entire insurance market will now only pay for low-cost generics, and this is the result...you will get garbage medication. You need to insist that your insurance pay for the brand name."

• Kim...
• Taken for 1 to 2 years
• February 25, 2025

"I'm 56, been postmenopausal since I was 46. I'd suffered such terrible hot flashes since I was 42. I just figured it was par for the course...but the hot flashes were so bad that I'd never had a full night's sleep since they started. Lack of sleep snowballs into a myriad of bad symptoms, brain fog, crappy memory, mood swings, zero libido...etc. I even lost my job because my memory was that bad! This went on and on until I seriously couldn't live like that anymore. So almost 2 years ago, I gave in and talked to my gyno, who immediately started me on the lowest dose Estradiol patch along with a progesterone gel cap. I felt relief after the first week! Hot flashes went away, and I felt like I had my life back. My dosages had to be tweaked along the way. Now the patches aren't strong enough, and I'm starting on a 2 mg estrogen pill. HRT is NOT the horrible drug they assumed back in the 70s. It's a lifesaver! And it's covered 100% by Wellpoint Insurance (NJ Medicaid), so there's no excuse!"

• Not...
• Taken for 1 to 6 months
• October 5, 2021

"Dotti 0.05 patch claims to be equivalent, but the stated amount of estrogen is less than the estradiol 0.05 patch. Six weeks after I was switched to Dotti by a pharmacy, I had horrible symptoms. Went back on the estradiol patch, and I am better. Safeway, Humana, and Costco are all using the Dotti patch. This patch should be pulled from the market."

• mar...
• Taken for less than 1 month
• June 6, 2021

"My drug store replaced my Estradiol patch with Dotti. The first night, my restless sleep and dreaming. Daytime, I was cold and couldn't get warm. The second night, I experienced terrifying nightmares, woke up drenched in sweat two times. I was frightened, didn't know what was wrong with me. Figured it out! Another drug store was able to fill my regular prescription, and I was fine within a few hours. I question if this drug passed trials as a replacement for Estradiol."

• Suz...
• Taken for 1 to 6 months
• March 1, 2023

"My pharmacy changed to Dotti brand manufacturer at the end of November 2022. I loved how the estrogen patch was smaller and less visible. However, my postmenopausal symptoms started back within three weeks of beginning the Dotti patch. I had increasing hot flashes, dry skin, brain fog, and fatigue. I scheduled an appointment with my OB/GYN in February to have my hormone levels rechecked. She discovered I had almost NO estrogen in my system. NONE. She said my body was not absorbing the medication. However, I have not had problems absorbing any other brand over the last 4 1/2 years. The Dotti brand estrogen patch was useless for me. I had to switch pharmacies to use a different manufacturer."

• Rho...
• Taken for 1 to 6 months
• August 25, 2021

"I had been on another estradiol patch for about a year. My husband's employer requested we start using a mail prescription, and when we did, they switched me to Dotti patches. I started wondering why I was feeling crabby and irritable again, sort of like I did before taking the patches. Also, I’ve been gaining weight. Not sure if that is also from the patches. But I’ve requested switching back to my original patch. I still wasn’t sure if this was because of the Dotti patches, but after reading these reviews, I’m sure of it. Would not recommend."

• Lis...
• Taken for less than 1 month
• June 25, 2023

"I used this convenient little patch for a week, and I began to experience symptoms related to blood clots: ankles were so swollen, I couldn’t see my ankle bones, so my doctor prescribed compression socks. Other symptoms were dizziness, nausea, shortness of breath, and headaches. I removed the patch, and within 24 hours, all symptoms disappeared. I’d have ended up in the emergency room if I had kept using this patch."

• kda...
• May 2, 2021

"I switched pharmacy and was given the Dotti patch rather than the Sandoz patch like I had before. Immediately, my energy level dropped, chills, headache, and drenching night sweats. This is not for me!"

• Lov...
• Taken for 1 to 6 months
• February 17, 2023

"Immediately after being switched from Sandoz to Dotti, my body went into the same horrible rigid muscle pains and terrible foot aches scenario that I had experienced prior to getting on any HRT. I dealt with it for 5 months and then asked to be put back on Sandoz. Within a week back on Sandoz, the horrible foot pain eased. After 3 weeks back on Sandoz, all the muscle pain and foot pain, as well as the sleepless nights that had returned, went away. I feel full of energy again too. I kept my Dotti package because I thought maybe it was a recall situation and I had gotten a bad batch for a number of months, but I haven't seen any recalls for it. All I know is that it absolutely doesn't work for me."

• Hot...
• September 2, 2020

"Been having major hot flashes, lack of sleep for 2 years. Just was given Dotti 0.25 mg patch. On my 7th day and I notice a difference. Not flashing as often, and I have actually slept the past couple of nights. I go see my doctor tomorrow for a follow-up. My only concern is the risk of cancer. I will discuss this tomorrow. My mood has also improved! So far, very happy with this."

• KPa...
• Taken for less than 1 month
• July 22, 2021

"I was so relieved to find these reviews. My doctor uses another pharmacy for 'ease' and, as a result, I got the Dotti Estradiol patch. I used it for four days. It does not work. I got hot flashes, red patches, mood swings -- the works. It felt like life was so bleak. Less than 10 hours back on Sandoz and things are looking up again. Red patches gone. No hot flashes... Why do they even make this patch?!"

• Lit...
• Taken for less than 1 month
• January 13, 2021

"One week using Dotti, experienced marked increase in vasomotor symptoms, mood swings only relieved by switching to another manufacturer. Amneal representative stated to me it's not in their policy to replace. Let the buyer beware!"

• Pat...
• Taken for less than 1 month
• August 24, 2021

"I had a terrible vasomotor reaction. First and last time I used it, after 18 hours, the patch bottomed out, and I started having hot flashes. I was shaking, had a brain-buster headache, and severe nausea. Fortunately, I still had some of my generic Noven patches left over. I ripped off the Dotti and put on the one I usually used, and within 30 minutes, I was fine. Dotti is garbage, yet pharmacies are pushing it right now. Must be getting paid to do so."

• Ann...
• August 21, 2020

"This patch was forced on me by my pharmacy, saying it worked the same as my other brand patches, but that was not true. After a week of using them, I started having horrible hot flashes and could not sleep. A waste of money. I went back to my regular ones and lost the money I paid for the Dotti."

• Mar...
• Taken for 1 to 6 months
• November 1, 2019

"This Dotti patch doesn’t work! Provided no relief. Went from a stable estrogen level on another brand to 43 by the time I quit it. It doesn’t work. Went back to the other brand and instantly got relief from hot flashes and mood instability."

• fru...
• Taken for 6 months to 1 year
• February 20, 2021

"I moved, which required changing pharmacies. I was on a different patch in my other state, and my new pharmacy offered Dotti. I had no idea why my hormone levels were dropping, why my moods went from happy and energetic to exhausted and depressed, with bouts of anger. I would not recommend this manufacturer. It started off okay, but I was still cycling through my old patches. A couple of weeks later, I lost all interest in anything and even had to make an appointment to see someone for major depression (never felt that before). Please beware. I have been using Dotti for 3 months and had to request pills on top of it to compensate for the drop in my levels."

• cva...
• Taken for 1 to 6 months
• June 3, 2023

"I'm horrified by what I'm reading, and now I think I know what's wrong with me. Menopause for 3 years. Dotti is what I'm using since insurance stopped paying for Estradiol. I've been having terrible symptoms and couldn't figure it out. Dry skin and hair, insomnia, night sweats, easily irritated, fatigue, and I've just had a period?!? Had all the old premenstrual symptoms such as breast tenderness, cramps, and a 4-day period, and MOODY. I do have an appt with my OB/GYN. If Dotti is the reason, I am not happy, as it seems NO ONE likes this patch!"

• Anonymous
• Taken for 1 to 6 months
• May 7, 2023

"This patch is horrible. I have scar marks from where the patch was placed on my inner thighs. My allergies are out of control. My irritability and hot flashes are back. I’m so angry that my pharmacy switched from Vivelle Dot to this patch when I found out I switched to another pharmacy, and they also sent me the Dotti patch. My insurance pays for name-brand medication, so this is completely unacceptable. I’ve asked the pharmacist in the past if this is the same medication, and they say they use the exact same quantities of the drug as the name-brand. I do not recommend this product."