Estradiol topical and Pain: What Users Say (Page 2)

• Mum...
• Taken for less than 1 month
• March 15, 2025

For Atrophic Vaginitis "I was prescribed Vagifem after a failed smear test. The nurse couldn’t perform the smear test because she said I was very inflamed. It did hurt, so I wanted her to stop. I had no symptoms of VA until she tried to insert the speculum. I was prescribed 2 weeks of Vagifem and told to return on the 3rd week. The first week was grand, all went to plan. Insertion was fine until the first day of week 2, and oh my God, I just couldn’t get the applicator to insert fully. It was like it was hitting a brick wall, the pain was horrible. So I phoned the nurse who said that was normal and not to force it, just insert as far as possible and release the tablet. But the pain when I click the button was like I was letting off a bullet into my vagina. I could feel the tablet fire out and a sharp pain, but then the pain goes away fast. But I have lots of blood. The thought of having to do it puts me off using Vagifem. I’m not sure what’s causing the applicator to not fully insert until I see the nurse again."

• Anonymous
• March 11, 2010

For Atrophic Vaginitis "I am 59, and it got to the point that I was avoiding sex. I had pain with intercourse and had to use lubricant all the time. I use 4mg once a week and am enjoying sex for the first time in years."

• Joy...
• February 19, 2016

For Atrophic Urethritis "Awful leg pain, vaginal burning like on fire, back pain, pounding heart, dry cough, stomach pain, and diarrhea"

• Anonymous
• Taken for less than 1 month
• August 15, 2022

For Atrophic Vaginitis "Blurred vision and floaters after a month on this drug. I have stopped taking it, eyesight is improving, and I was having pain when putting contacts in. Will never use this medicine again."

• mir...
• Taken for 1 to 2 years
• September 15, 2017

For Atrophic Vaginitis "I had a hysterectomy at 22, so my doctor prescribed this over a year ago. I'm not as dry, but still pain from the thinning of the walls. Hopefully, after a longer time, this will get better."

• Pen...
• Taken for 2 to 5 years
• May 19, 2022

For Atrophic Vaginitis "I'm 54 years old and have noticed that the Estring's effectiveness has plummeted in the last year. Used to work like magic, now sex is so painful I cry. Deal breaker when they're $400!"