Estradiol topical and Pain: What Users Say (Page 2)

• Rel...
• Taken for 6 months to 1 year
• March 7, 2025

For Atrophic Vaginitis "Having entered full menopause 2 years ago, I’m now 61. I found my vagina/labia was completely dry a year into menopause (it had been getting worse starting the year before). Sex was dry and painful, and required a lubricant, otherwise, the skin was raw and sometimes bled. My gyno recommended the Estring. It started working noticeably by day 3, and 2 weeks in, I felt normal again. The ring looks large out of the package and requires some patience to insert. The first insertion, I could feel it riding on my cervix. I needed to push it further to the top of the uterus - that worked, and I could not feel it. I am now on my 2nd one (they are good for a 3-month window). It is a $60 co-pay, so it works out to $20 a month. I haven’t had any problems with it, and I am very happy so far. I would recommend anyone try it and see if it works as well for them as it has for me (it doesn’t have the hassle or mess of suppositories or creams). I recommended it to a friend of mine as well."

• Ano...
• Taken for less than 1 month
• June 25, 2025

For Atrophic Vaginitis "I also am having extreme burning after applying only a pea-sized amount of the Estrace cream. The burning feels like a urinary tract infection, even though it's not. I use it only twice a week. I don't understand how such a small amount of the cream can cause so much burning and pain and inflammation. Dr. tells me to keep using it and the issues should subside, but I don't know. I am 69 years old and had a complete hysterectomy 25 years ago."

• Anonymous
• March 11, 2010

For Atrophic Vaginitis "I am 59, and it got to the point that I was avoiding sex. I had pain with intercourse and had to use lubricant all the time. I use 4mg once a week and am enjoying sex for the first time in years."

• Joy...
• February 19, 2016

For Atrophic Urethritis "Awful leg pain, vaginal burning like on fire, back pain, pounding heart, dry cough, stomach pain, and diarrhea"

• Anonymous
• Taken for less than 1 month
• August 15, 2022

For Atrophic Vaginitis "Blurred vision and floaters after a month on this drug. I have stopped taking it, eyesight is improving, and I was having pain when putting contacts in. Will never use this medicine again."

• mir...
• Taken for 1 to 2 years
• September 15, 2017

For Atrophic Vaginitis "I had a hysterectomy at 22, so my doctor prescribed this over a year ago. I'm not as dry, but still pain from the thinning of the walls. Hopefully, after a longer time, this will get better."

• Pen...
• Taken for 2 to 5 years
• May 19, 2022

For Atrophic Vaginitis "I'm 54 years old and have noticed that the Estring's effectiveness has plummeted in the last year. Used to work like magic, now sex is so painful I cry. Deal breaker when they're $400!"