Elagolix User Reviews & Ratings (Page 5)

• Eynlyn
• Taken for 1 to 6 months
• October 27, 2020

Orilissa (elagolix) for Endometriosis "I've only been taking Orilissa for a little over a month. I haven't noticed any side effects other than mild hot flashes and weight gain, but I also haven't noticed any difference to my pain. The only difference is that my nausea is a bit better than before. I still get it consistently, but not as bad. My doctor prescribed this to help with inflammation before my surgery. Was supposed to get Lupron, but it's constantly on backorder. Also, my insurance said they wouldn't cover it, but somehow my pharmacist got authorization, so make sure to check if your pharmacy has tried to get authorization."

• Scion...
• Taken for 6 months to 1 year
• July 10, 2022

Orilissa (elagolix) for Endometriosis "I first took Orilissa after having a laparoscopy to verify I had Endometriosis. I do not recommend this. Prior to taking Orilissa I was prescribed birth control pills, the implant, and the depo shot. I had bad side effects with all those other treatments. Now I have to say for me, Orilissa was NOT worth the trouble. I gained 50lbs in 6 months, got acne, was constantly hot even in 40° F weather with no jacket and sleeveless top, irritable beyond belief, and had had what I can only describe as "fly like" symptoms the entire time 6 months I was taking the medication. My whole body ached terribly, I was nauseous and I had a headache that would not go away . I tried taking to my doctor about all my symptoms and she made me feel like she just didn't care. She told me that if my pain came back (it never fully went away) that she would put me back on it. So, I haven't been back to that doctor. I'm now searching for a doctor that will give me a hysterectomy."

• Giselle
• Taken for 1 to 6 months
• June 23, 2022

Orilissa (elagolix) for Endometriosis "I was prescribed Orilissa 200mg as an alternative to a hysterectomy due to uterine fibroids. My periods became much lighter and less painful right away but the headaches are almost everyday and then back pain and blurry vision started. I also started experiencing weird facial twitching which I have never had before or after Orilissa. I've always been the all natural, non hormonal girl so I don't know if this is why my body is so sensitive to this medication but I've decided to tough out the painful, heavy periods and anemia a little longer and hope for another option to surgery. Also, I forgot to mention the feelings of depression and mood swings that just are overwhelming."

• Sarah
• August 16, 2022

Orilissa (elagolix) for Endometriosis "I have Stage IV endo with heavy bowel and organ involvement. I took Orilissa 200mg for 6 months that was allowed by my insurance. After a few weeks taking the medicine I could tell a significant decrease in my endometriosis pain, but I started developing bladder spasms which I’d never had before. After 6 months of treatment on the high dose I was put on 150mg low dose for up to 18 months. Unfortunately I didn’t make it much longer on this medicine as I attributed the new interstitial cystitis pain to this medicine. I’m still not fully back to normal but the IC symptoms are improving since stopping this med a week ago. It was nice that my endo pain was nearly gone while taking Orilissa but felt I traded one pain for another which is so frustrating. If I hadn’t developed I.C. I would’ve gave this med 10/10 rating."

• Alexis
• Taken for 1 to 6 months
• December 15, 2021

Orilissa (elagolix) for Endometriosis "I started out with the 150mg tablets but they didn't work so my Gyno up the dose to 200mg a day. At first, I didn't really think I experience any help but by the 2nd to 3rd month, I felt a difference and my menstrual cycle stopped completely. I did experience some pretty nasty hot flashes and night sweats but that was the most, I thought, had occurred. I was told by my Gyno, that the loss of my cycle was normal and so were the other side effects, so I figured they knew what they were talking about with the drug. Until she told me about the bone loss side effects on my follow-up appointment by month 5 to see how the medication was working and then she dropped the bomb on me. She told me that I can only be on this medication for 6 months only because it is NOT FDA approved for longer than 6 months. I did experience bone loss in my teeth and I found this out just recently after having a tooth extraction and my dentist showed me. BE CAREFUL with the drug!! THEY DON'T KNOW ENOUGH ABOUT IT!"

• Anonymous
• Taken for 1 to 6 months
• February 20, 2022

Orilissa (elagolix) for Endometriosis "I was on Orilissa for a month. I have been off for two weeks and it ha completely screwed up my cycle. While on Orilissa my period was more painful and lasted 2 weeks. 1 week of extremely heavy bleeding and 1 week of spotting. I was very moody and depressed while on the medication as well. Due to the side effects and just not feeling quite right I stopped the Orilissa. However, I have only been off about 2 weeks and my cycle is still "off" My period returned a week after stopping Orilissa and I now have spotting after sex and cramping. I don't like this medication and wish I never took it. My cycles have never included spotting or been irregular prior to Orilissa."

• ENDOS...
• Taken for 1 to 6 months
• January 23, 2022

Orilissa (elagolix) for Endometriosis "I've been on Orilissa for almost 4 months. Reading the reviews I was a bit terrified I had tried everything else short of surgery. I had one period after taking it for less than a week and it was painful but I haven't had one since then. It has taken almost all my abdominal pain away including my bowel troubles and most of my urinary pain. It's so much more bearable. I have hot flashes here and there and have experienced lots of headaches my dr. Prescribed a very low dose of estrogen to help counter act the headaches hopefully. And says it shouldn't be enough to cause pain in my abdomen to increase. I would say that I'm more irritable than normal but I'll deal with it for now."

• bmfl
• Taken for 6 months to 1 year
• March 26, 2022

Orilissa (elagolix) for Endometriosis "I have been on Orilissa for almost a year. I went on the 200 mg dose originally and it helped a lot with symptoms of endometriosis but I was getting hot flashes and night sweats, and it has caused my mood to change a lot. I switched to the lower dose after about 3 months and have been on it since, but I feel like it is slowly becoming less effective. I don’t get hot flashes as often on the lower dose but I almost feel as though my emotions are dampened or very extreme so beware of this if you have a history of depression/anxiety. I love the company though they had a nurse who checked in on me to make sure I was doing ok and was able to get my prescription filled, and their program to pay for it is great if your insurance doesn’t cover."

• Half...
• Taken for less than 1 month
• October 11, 2021

Orilissa (elagolix) for Endometriosis "Has anyone else tried cutting the dosage much smaller? I was on the 150 dosage for less than one week and had side effects that were worse than the condition being treated. I experienced night sweats, but the mood issues were the red flag for me. Have not had panic attacks and depression like that in over 20 years. I tried stopping and re-starting with same result. But at the same time I experienced pain relief that I definitely need. So I am now taking less than half a dose. I am not sure if this is recommended, but I need the pain relief. I was surprised that it is not even period related for me. I have been having bad back pain that is likely a disc injury and it has totally disappeared on this medication. I also have less abdominal pressure and pain than normally, which was a major symptom for me. This is after taking a half pill every other day, that I am seeing these positive changes. I am going to keep this small dosage and see if the mood issues are not too bad."

• Jexxa
• Taken for 1 to 6 months
• August 14, 2021

Orilissa (elagolix) for Endometriosis "I've been doing trial and error of medications and OT and pain clinic for my endo for over a year. This was kinda a final thing for me to try before discussing a hysterectomy. I was extremely skeptical since I already have mood issues from mental illness but I was desperate. Immediately upon taking it I was extremely nauseous and I had the worst migraines, that persisted daily for two weeks. I would have stopped it Immediately just from that but unfortunately if I stop I'll end up in the hospital from pain if I'm left unmedicated. So I've been on it three weeks now mixed with max dose of norethindrone. I bled for the first two weeks, my daily cramps are still horrible, and the nausea and headaches are still there though not as bad. I also have HORRIBLE insomnia during the night yet I'm completely exhausted during the day and just want to sleep. This is the most side effects I've ever had from a medication. I absolutely don't like this med but I can't even discuss getting off of it until sept 1st."

• abigail
• Taken for 1 to 2 years
• November 19, 2020

Orilissa (elagolix) for Endometriosis "I start take this medicine Orilissa from April 2019, not much side effects on me, only feel joint pain. The most important thing I want to mention is that after keep taking the meidicine everyday at the same time for 1.5 year, I get my period again."

• Dani
• Taken for 1 to 6 months
• March 8, 2023

Orilissa (elagolix) for Endometriosis "I’ve been on it for about 2 months now and if it wasn’t for the debilitating pain in my left hip - to the point that I can’t lay on that side at night- I would be so happy with it. The pain just keeps getting worse and I’m afraid I’m going to have to stop taking it. It didn’t start hurting until I had been on it for about 2 weeks. I’m going back to my OB on Friday to see what she recommends."

• itsho...
• Taken for 1 to 6 months
• September 1, 2022

Orilissa (elagolix) for Endometriosis "I started Orilissa a couple months ago. It stopped my bleeding immediately and it was good for a decent minute. I had some hot flashes here and there but not too bad. After a month and a half or so, I started having frequent hot flashes, many times a day. I’d wake up sweating so badly. I felt like I was in an oven every time. I have been off of Orilissa for a week now and I am seeing some improvement in the flashes but wish it’d go away faster."

• phile...
• Taken for less than 1 month
• April 4, 2023

Orilissa (elagolix) "I have to say I agree with all the other reviews to not take this drug. I only took this drug for seven days and it was enough to make me think I was going to die. I took Lupron before I was prescribed this medication before starting my second IVF cycle for my Adenomyosis. Lupron was way better in regard to the side effects. I asked my doctor from Genesis Fertility which one was better and he said they work the same way, boy was he wrong. On the second day on this medication, I started spotting, hot flashes, night sweats, horrible dry patches on my face, joint pain, migraines, blurry eyes, insomnia, and terrible mood swings. These symptoms got worst with each passing day, especially the bleeding. By day 5 it was as if I was on my period again I was no longer spotting. On the morning of day 7, I decided that if I continued to take this drug it was going to kill me. I still wanted to tough it out and take the drug because I paid $1200 but ultimately I decided not to continue."

• Luano
• Taken for 1 to 6 months
• November 1, 2020

For Endometriosis "My experience with elagolix was not good at all. I continued with the pain, pain during sex, and painful periods. I had hot flashes, which compared to the other effects were ok. I also developed depression to the point I had to seek professional help. It is the just awful. If for other women it worked, I’m happy for them. But for me it is a big NO."

• Anonymous
• September 10, 2021

Orilissa (elagolix) for Endometriosis "I have to share this. I started Orlissa for endometriosis pain 5 months ago. I did try to stop it this month due to feeling very depressed. I have gotten my period every month routinely and that is when I stopped it. However the pain was surreal once I went off of it. I was chalking it up to period pains but by the end of the first week I was curled over. My stomach felt on fire, inflammed, sharp pains in front, back, and right side. I gave it 2 weeks and just couldn't take the pain anymore and started back on the Orilissa. After 2 doses the pain subsided and now I am on day 4 and its almost gone. I can still feel where all the pain was but I can definitely tolerate it. I guess my mental health is the price I gotta pay for my physical well being. None the less it definitely helps with my endometriosis pain. Going to call my Dr. to see where I go from here."

• dapha...
• Taken for 1 to 6 months
• August 25, 2022

Orilissa (elagolix) for Endometriosis "I really enjoyed the benefits of Orilissa the first few weeks. I immediately stopped bleeding and felt great about it. A few weeks in I started to have horrible hot flashes, many times a day and they’ve only increased if frequency. I also have a modd disorder and anxiety, which has been greatly affected by Orilissa in the past couple weeks (I’ve been on it 2 months). I cannot stand the way I feel and I will be discontinuing the medication as soon as I speak with my OBGYN."

• Kee
• Taken for less than 1 month
• May 5, 2023

Orilissa (elagolix) for Endometriosis "I just started Orilissa on Wednesday of this week and before that I was on Medroxyprogesterone to control my bleeding from endometriosis, and it was helping fine. But three weeks ago, I started back spotting with dry old blood. Then it turned bright red, then dark to spotting again. I dealt with it for like a week, then I reached out to my obgyn and was like I need something to stop this breakthrough bleeding! It's horrible. Now I'm on 150 mg Orilissa, and I have no side effects as of yet, outside of migraines and heavy bleeding. But did anyone experience bleeding in the beginning of taking this medication? I'm hoping it will help me to stop the bleeding and endo pain and symptoms. I'm also stage 4 ednometriosis"

• Macke...
• Taken for 2 to 5 years
• June 27, 2023

Orilissa (elagolix) "After my authorization ran out on my Lupron, my insurance sent my doctor information about this medication and he was all for it. I've never heard of any trans women taking it. I prefer taking pills to shots, so I tried it and it's wonderful. My testosterone levels are lower than they were on Lupron (30-40s on the shot vs. 10-13ish on Orilissa). The peach fuzz above my lips disappeared completely, and I no longer have to wax. When my pharmacy can't get my estrogen patches, hot flashes start after a few days and get intense if I'm without E for more than a week. I'm no stranger to hot flashes, but wow. I don't ever recall them ever being this intense when I was only on Lupron. The blister pack is annoying to deal with, but otherwise, I have no actual complaints against this medication. I feel awful for the endo women who have to take this and can't have any estrogen."

• Ash
• Taken for 1 to 2 years
• May 14, 2022

Orilissa (elagolix) for Endometriosis "I have been using Orilissa for about 2 years now. It has worked tremendously at managing my endometriosis pain and has somewhat given me back normal way of life. However, the past 6 months I have been noticing a difference. I have been experiencing joint pains and increased back and abdomen pain. I also had a suicide attempt a few months ago and since then I have been prescribed zoloft. I would recommend short term. But I haven't been able to find an alternative long term solution for endometriosis."

• tired...
• Taken for 1 to 6 months
• December 10, 2022

Orilissa (elagolix) for Endometriosis "I've only taken it for 5 weeks and I've literally had a headache everyday since I started I would trade the abdominal pain for the headaches. My vision seems a little off also, I am not sure if it is due to the headaches or another side effect. I've had more abdominal/pelvic pain since starting also. My dose is 200 mg 2x a day."

• Rebel
• Taken for 1 to 6 months
• December 20, 2022

Orilissa (elagolix) for Endometriosis "I was on it in 2019 for approx. 3 months. I’m also on some really strong Epilepsy meds; and this was one of 2 medicine approved by my Neurologist & Gynecologist for my endo. I had some severe joint pain; an increase in my migraines, and an inability to sleep. And while it did get rid of my period; the side effects were not worth staying on the drug."

• Lynn
• Taken for 1 to 2 years
• September 23, 2020

Orilissa (elagolix) for Endometriosis "DO NOT TAKE THIS MEDICATION!!! I took Orilissa for 1.5 years and just found out today I have osteoporosis! I'm only 37 years old. I'm in so much pain all the time!"

• halbal
• Taken for 1 to 6 months
• April 4, 2022

Orilissa (elagolix) for Endometriosis "I take 200mg twice daily. I’ve had no side effects and my pain is almost non existent. Before Orilissa, I was in pain almost daily."

• Van
• Taken for 6 months to 1 year
• April 10, 2023

Orilissa (elagolix) for Endometriosis "I suffered some side effects for the first 6 months but after that little to none. Has dramatically decreased my endometriosis pain and has largely given me my life back."