Dulaglutide and Headaches: What Users Say (Page 2)

• Tam...
• Taken for 1 to 6 months
• July 24, 2019

For Type 2 Diabetes "I have uncontrolled type 2 diabetes. I have taken Trulicity for 4 weeks because my Dr. said the symptoms would subside. I have stomach cramps, nausea all day, a headache, and just sorta malaise. I will not inject another shot. I gotta figure something else out."

• beb...
• March 9, 2016

For Type 2 Diabetes "This is my second week on Trulicity. Nausea (comes and goes), abdominal cramping, constant full feeling. Guess that's what helps you lose weight. Who wants to eat when they feel like they just ate? UUUUGH!!! Headaches all day, muscle at base of neck on left side hurts. No diarrhea, thank God (yet anyway). Just an overall not-so-good feeling. Not sure if I will stay on this med, but trying it out to see if it lowers my sugar. I can deal with nausea, but stomach pain and diarrhea, no way."

• Swe...
• January 26, 2016

For Type 2 Diabetes "First 6 weeks was on 0.5, had a little cramping, headaches, mild reflux, nausea, this usually happens on the 2nd day after the injection. My blood sugars were so excellent that my insulin pump would have low readings at night. My appetite was no longer, and I was losing weight. Then on the 7th week, the dosage went up to 1.5. Well, let's just say I ended up in the ER. My cramping was horrible, didn't get any sleep because I was projectile vomiting, diarrhea, heartburn, muscle tightening, and severe headaches. I became extremely dehydrated, so for 3 days, I was a mess. But in all, my sugars stayed regulated and would only recommend staying on the 0.5. I don't know what my A1C is yet, but blood sugar numbers are excellent. Side effects not worth it."

• Swe...
• January 26, 2016

For Type 2 Diabetes "First 6 weeks was on 0.5, had a little cramping, headaches, mild reflux, nausea, this usually happens on the 2nd day after the injection. My blood sugars were so excellent that my insulin pump would have low readings at night. My appetite was no longer, and I was losing weight. Then on the 7th week, the dosage went up to 1.5. Well, let's just say I ended up in the ER. My cramping was horrible, didn't get any sleep because I was projectile vomiting, diarrhea, heartburn, muscle tightening, and severe headaches. I became extremely dehydrated, so for 3 days, I was a mess. But in all, my sugars stayed regulated and would only recommend staying on the 0.5. I don't know what my A1C is yet, but blood sugar numbers are excellent. Side effects not worth it."

• Lun...
• Taken for less than 1 month
• February 17, 2020

For Type 2 Diabetes "Took my first Trulicity injection this past Friday. Felt horrible ALL weekend and not able to do anything; barely got off the couch! Have terrible nausea, vomiting, and diarrhea. Lost my appetite and not keeping food down. I have also had a terrible headache since Saturday. Taking this is worse than the actual condition. Will no longer take it. I cannot work like this!"

• Deb...
• April 18, 2017

For Type 2 Diabetes "Well, I am 24 hours into the shot and so far (knock on wood) the only side effect is headaches (which I never have), but I can deal with that. My morning blood reading would normally be about 169, and I got up this morning, and it was 75. Just wondering how many days into it the side effects (nausea & vomiting) started with people that did experience these effects? Will keep you posted after the week is up....."

• der...
• Taken for 1 to 6 months
• July 6, 2017

For Type 2 Diabetes "Addendum to June 13th post: My A1c is 7.2, down from 9.2 in May. That's 2 points in 2 months. Yay!!!! My Endo was very pleased. He started me on Trulicity 0.75 in May because I was having GI issues with Janumet. I've had no nausea or diarrhea with Trulicity. Only mild headache, decreased appetite, some abdominal soreness/achiness, and low blood sugars during the day. Now, I take 5-10 units of Novolog prior to meals and at times none at all depending on my blood sugar reading. My Levemir has decreased as well-I take 42 units at night vs. the previous dosage of 50 units twice daily. My weight is down 6 lbs. I recently filled a prescription for a 90-day supply of Trulicity and did not have a co-pay. Overall, I am pleased."

• abe...
• Taken for less than 1 month
• October 27, 2016

For Type 2 Diabetes "Took 2 doses of 0.75 Trulicity a couple of months ago (over 2 weeks) and got severe flu-like symptoms. Nausea, loss of appetite (which was expected), headaches, lethargy. Symptoms didn't start for a few days, so it's hard to tell if it is definitely a cause. Stopped taking it and gave my body time to feel normal again to rule out actual flu. Took another shot this Sunday evening and felt fine until Thursday when I woke with all the same flu symptoms again. Now I'm pretty sure it's the Trulicity and will not be taking it again."

• Sue...
• Taken for less than 1 month
• August 27, 2017

For Type 2 Diabetes "I took Trulicity 1.5 for the first time Wednesday. Within hours, I felt sick, tired, and had the most awful headache. I slept most of the day, no food. Thursday, I woke feeling hungover. I made a coffee and was immediately sick. A lump appeared in the side of my neck, went after a few hours. Friday, I felt better, had some toast, but then the watery diarrhea kicked in. Saturday, I managed one Weetabix. By lunchtime, I fancied a Happy Meal (don't know why, as I've never wanted one before). Big regret, as I suffered bad diarrhea all day and slept all day and night. Sunday, still no appetite, not so tired, diarrhea subsided, slight headache, but I've lost 5 lb. My sugars are a consistent 5, and I've reduced NovoMix from 90 units to 40 units. Will I take it Wednesday? I'm not sure."

• ont...
• Taken for 1 to 6 months
• June 14, 2016

For Type 2 Diabetes "Started 1st shot 9 weeks ago .75. No nausea, but not hungry at all. Still also taking Metformin 1000 and Glipizide 20 mg at the time. Into the 7th week, stopped the Glipizide, but still on the Metformin, started feeling the nausea and constipation. I also experience fatigue and headaches. My A1C is down from 7.6 to 6.5 now and have lost 10 lbs so far. Anyone else not get the side effects until the 2nd month? I feel like my experience is different from the majority. Going to continue unless it becomes unbearable."

• Ran...
• Taken for 1 to 2 years
• May 23, 2017

For Type 2 Diabetes "I have been on Trulicity 0.75 for a little over a year. I seem to be nauseated and have headaches each week on the day after. When I first started taking Trulicity, it was more like 3-4 days of feeling sick, with horrible headaches. My A1C went from 13 to an 8 (also taking Tresebia daily), and I haven't noticed any side effects, with the exception that when I would take both shots first thing in the morning (on opposite sides). I find that when taking both of these medications, I take Tresebia first thing in the morning every day, and Trulicity around noon (once per week), making sure to shoot them on opposite sides. This has so far helped with the nausea and headaches, also sipping on lemon water with crushed ice. Hope this helps."

• nug...
• Taken for less than 1 month
• October 9, 2016

For Type 2 Diabetes "I did my first shot 10 days ago. Side effects were the worst I've ever experienced on a medicine: extreme nausea, headache, vomiting, and the diarrhea was extreme and very bad smelling with bad smelling sulfur-like burps. I thought maybe I caught a bug, but after reading others' side effects, I'm sure it was the shot. My husband is totally against me taking it again, and I'm now agreeing with him. Yeah, my sugars went down because I couldn't eat for almost 9 days, and nausea medicine didn't help at all. You lose weight because you can't eat. I was really hoping this would help because I don't want to go on insulin. I finally took something for the diarrhea and am feeling almost normal again."

• Kit...
• Taken for less than 1 month
• January 27, 2022

For Type 2 Diabetes "I've been on this medication for only a week, and yesterday I woke up with sulfur burps and nausea so bad that I couldn't function half the day. Then today I felt great half the day, I finally ate at 2:30 a peanut butter sandwich. Within an hour, I started getting a headache that turned into a migraine, sulfur burps returned, and nausea so bad I feel like I can puke up my whole stomach if I had any food in it. I'm feeling absolutely horrible."

• pra...
• Taken for less than 1 month
• September 11, 2019

For Type 2 Diabetes "I've had type 2 diabetes for 10 years - have always been on Janumet and Glicazide, and my A1C is between 6.5 to 7.5. I surge in A1C because of my diet (cravings after I started Keto). Had the first shot of .75 two days ago. Now on Trulicity, metformin, and Glicazide with advice to reduce Glicazide based on the outcome. Will be 1.5 from next week. My experience so far, Day 2: ------ - dull headache in the morning (never had a headache in my life before). - No diarrhea/nausea as reported by some."

• Ter...
• Taken for less than 1 month
• May 30, 2016

For Type 2 Diabetes "The PA in my endo office thought I would benefit from this even though I'm type 1 but showing signs of insulin resistance. Taking this injection was one of the biggest mistakes of my life! I've experienced extreme nausea, severe headaches, and heartburn from mild to severe. I've vomited one time, which made me think back to when I had food poisoning from eating crab, which was an awful experience. It's now 5 days after taking the first injection, and the above symptoms have lessened. No real appetite, and when I do eat, my stomach is queasy. I will not be continuing with this medication."

• bam...
• December 4, 2016

For Type 2 Diabetes "I have taken Trulicity for four weeks now. At first, I had bad side effects: headache, nausea, diarrhea with terrible cramping. But each week it lessened. Now into the fifth week. Doing much better. Still have no real appetite, have to remind myself to eat. But my blood sugars are down! That was my main objective. Haven't lost any weight, though. But still glad that I hung in there and got through the adjustment period."

• Stu...
• Taken for less than 1 month
• May 22, 2018

For Type 2 Diabetes "I started Trulicity a week and a half ago. Side effects were a few minor headaches, one migraine-which may not be related as I've had them in the past. Heartburn on the second day. One low blood sugar event 24 hours after the shot. Some burping. Feeling of nausea which only lasts for about a minute but could be a few times a day. Less appetite-lost 3 lbs. General malaise after eating for an hour or so. BUT it is getting better, symptoms reducing. Blood sugar readings excellent. 87 after work. 130 after meals. (sensible meals) 90-100 in the AM. Pretty impressed."

• Ren...
• Taken for 1 to 6 months
• July 18, 2016

For Type 2 Diabetes "Had to switch to Trulicity when Ins. wouldn't cover Bydureon. T. shot is much easier to use. Lost a few lbs due to nausea. I have stomach pains, gas, constipation, headaches, bloating, and full feeling. My body just aches. I take water aerobics 4 nights a week. Consider myself very active & this has slowed me down in class. I'm more tired & really dread having to mow the yard. I did lose about 8-10 lbs. It didn't stop me from wanting sweets or eating. I have been able to back off Novolog completely & cut my Levemir down 10 units. I take Metformin & Glimepiride. My A1C down to 5.9. Had extremely low readings (40's-60's) & the doctor wants me to bring numbers up now! I will continue to use because it works for sugar, but it is rough on the rest of me."

• Kim...
• Taken for less than 1 month
• August 2, 2019

For Type 2 Diabetes "This is my second time trying Trulicity, and it’s still taking me down. Within 3-4 days of injection, I’m bedridden. Can’t keep food down, throwing up and stomach pain. I’ve lost seven pounds in two weeks. Nausea, vomiting, and complete lack of appetite will do that. Constant headaches too. Trulicity is terrible. Going to quit again."

• LAB...
• Taken for less than 1 month
• July 22, 2018

For Type 2 Diabetes "Had my first Trulicity dose Thursday, and I have NEVER felt this bad! Headache, nausea, vomiting, diarrhea, heartburn (and I can't keep anything down or in). Sugar keeps going low because I can't keep anything down. I'm sorry, but I will not take this again! I'd rather take insulin than feel like this."

• Reb...
• Taken for less than 1 month
• June 12, 2017

For Type 2 Diabetes "I am a pre-diabetic and overweight and was prescribed this to help lose some weight. In my opinion, this drug is horrible. Took my 1st and ONLY injection Thursday, come Friday night I could barely move. My stomach and sides were so sore. Saturday I slept all day, had a low-grade fever, severe stomach pains, nausea, loss of appetite, headache. Sunday I went to the ER because I got worse and couldn't take the stomach pain. The doctor said it was a reaction from this drug. He gave me fluids due to dehydration from explosive diarrhea and morphine for severe pain. Today I left work early because not only am I having horrible diarrhea, I am vomiting like crazy. Low-grade fever again. I feel so sick. I would not recommend this medication at all. Of course, you're going to drop weight from vomiting and diarrhea."

• Anonymous
• Taken for 1 to 6 months
• June 14, 2017

For Type 2 Diabetes "I have been on Trulicity for 10 weeks. The first month I lost 13 lb, but nothing more. I still get a headache the day after the shot and a little upset stomach. Still helps my cravings a lot. Just wondering if aggravation is a sign. Just started doing this about 2 weeks ago. My sugar has dropped low to where I start to shake and feel sick to my stomach. I feel like it has helped."

• Pat...
• Taken for 1 to 6 months
• July 25, 2019

For Type 2 Diabetes "This stuff felt like it was killing me. Had all side effects you can list except for tumors. The brain fog was the worst, along with slurred speech, headaches, not being able to eat, couldn’t drive till my head cleared. It was driving me crazy. I will never recommend this to anyone. It left me unable to think for myself. My sugars were all over the place, up and down in a matter of an hour. Took it for three weeks, and I promise never again."

• Hor...
• Taken for less than 1 month
• May 26, 2017

For Type 2 Diabetes "Type II for about three years. Has been somewhat uncontrolled for two years. On 2000 mg Metformin and started Trulicity two weeks ago. Both weeks, on day 3 after the shot, I've experienced severe nausea and headache for about 4 hours. Other side effects are minimal, but annoying. I'm optimistic that side effects will go away over time as they did with Metformin. The medication is working, though, my fasting AM blood sugars have been in the 170-200 range, and this morning it was 115."

• der...
• Taken for 1 to 6 months
• June 13, 2017

For Type 2 Diabetes "Addendum to May 31st post: I'm still taking Trulicity .75 mg/.5 mL dosage, approaching week 5. My blood sugars continue to improve; fasting blood sugars 110-130; 2-hour post-meal blood sugars"