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Safyral and Acne: What Users Say

Acne: mentioned by 16 users (23.9%)

Based on user experiences from 67 Safyral reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

cramps 31.3%
mood swings 29.9%
acne 23.9%
depression 20.9%
bloating 19.4%
weight gain 19.4%
bleeding 16.4%
nausea 16.4%
sore breasts 16.4%
moody 11.9%

Reviews for Safyral

Commonly mentioned side effects
  • Koj...
  • May 2, 2013

For Birth Control "Been on Safyral for 6 weeks. I have no complaints. I've never been on birth control but had to go on it due to bleeding for 2 months straight, really heavily. My bleeding stopped, I've not had any mood changes, weight gain, acne, or anything. It's regulated my periods, and now I'm back to normal. It's been a great first experience with birth control."

10 / 10
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  • Bet...
  • September 21, 2014

For Birth Control "I was concerned about starting Safyral after reading some of the reviews here, but have been pleasantly surprised by how easy my transition onto it has been. I was not on any contraceptive previously, and when I started my Safyral regimen my only side effect was very light spotting for the first month. Not only did I escape mood swings, weight gain, acne, nausea, etc., but my usual menstrual symptoms (bloating, cramps, breakouts) have become almost nonexistent. I am not yet sexually active, so I can't speak to Safyral's effectiveness as a contraceptive, but I've been very happy with it in the meantime."

10 / 10
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4 Report
  • Bet...
  • September 21, 2014

For Birth Control "I was concerned about starting Safyral after reading some of the reviews here, but have been pleasantly surprised by how easy my transition onto it has been. I was not on any contraceptive previously, and when I started my Safyral regimen my only side effect was very light spotting for the first month. Not only did I escape mood swings, weight gain, acne, nausea, etc., but my usual menstrual symptoms (bloating, cramps, breakouts) have become almost nonexistent. I am not yet sexually active, so I can't speak to Safyral's effectiveness as a contraceptive, but I've been very happy with it in the meantime."

10 / 10
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  • Ang...
  • March 24, 2015

For Birth Control "I just finished a package of Safyral yesterday, and so far I've had no weight gain, my acne has cleared up some, and my period came when it was supposed to. However, I have had spotting all through the first month, which the doctor said was normal, so I have no complaints other than one really big one. While being on this pill, I have had serious depression. I'm always moody, crying, and sad. I am so sad that I have no appetite, no desire to go out, I'm never happy. In fact, I get raging angry sometimes, and I cannot control any of this. I am hoping that this side effect goes away soon."

5 / 10
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  • Anonymous
  • January 10, 2012

For Birth Control "Been on this birth control now for 4 months. It works well as it prevents pregnancy, but so far, I've had very heavy periods and severe cramps and tons of chin acne. Yaz never gave me these issues. I want to switch, but the doctor told me to give it another 3 months to see what happens. If I still don't like it, then she said I can switch. I must stick it out until then."

4 / 10
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6 Report

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  • Anonymous
  • Taken for 6 months to 1 year
  • May 12, 2012

For Birth Control "I have been on this for about 6 months now and started on it to help with my irregular and heavy periods, as well as a contraceptive. Let me just say all women's hormones are different, but for me, this works. Don't have acne (never really had a problem with it before). I start my pills on a Friday, and when I finish my active pills, I have my period on a Tuesday/Wednesday. It's prevented pregnancy (I'm only 21, don't want a baby) and keeps my periods in check. I love it!"

10 / 10
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  • Can...
  • June 28, 2015

For Birth Control "I started Safyral in April for irregular menstrual cycle and severe PMS. My only complaint was that for about a week or two, I was spotting off and on, but my periods are very light. I'm used to a very heavy flow, no backaches, cramps. I still will get an occasional pimple, literally 1 or 2, a few days before my cycle, but no acne, mood swings, or depression. My only regret is not starting this sooner."

10 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • May 4, 2012

For Birth Control "I have been on this birth control for about a month and a half now. This is my first time on birth control, so I did not understand all the changes that were going on. BUT I started craving so many things, and also nausea will come! Also, many mood swings, especially when my period is near, all I want to do is cry, and acne was HORRIBLE. I did not gain weight or anything like that, though."

6 / 10
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  • Anonymous
  • August 9, 2011

For Birth Control "I have been on this pill for five months now, going on 6. I was on Ortho Tri-Cyclen Lo for years, almost 10, then my body started to reject it. But I loved it. Perfectly timed periods and no side effects whatsoever. My doctor switched me to Natazia. Terrible. I had terrible acne and ridiculous bloating and weight gain all in my stomach area. I work out regularly and eat healthy. My only vice is alcohol. So after three months on that pill, I was switched to Safyral. I get very bloated one week before my period. My period is very heavy. I get bad cramps, although this month they seem to have subsided, as today is the first of my placebo pills and no cramps this month. But I am very bloated. Acne minimum."

6 / 10
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  • Lap...
  • October 23, 2014

For Birth Control "I've been on this for about a month, and the first week was great. But then I started to bleed heavily, and it hasn't stopped for two weeks. I've got bad back aches and terrible acne, as well as bloating. I'm looking forward to switching off this and onto Lo Loestrin Fe."

5 / 10
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  • Anonymous
  • Taken for 2 to 5 years
  • August 8, 2013

For Birth Control "I have been on this pill for two years. I switched to this from Ortho Tri-Cyclen because I was having breakthrough bleeding. One month into it, I was having terrible cystic acne, two months into it, I had a severe panic attack. Two years later, I am incredibly depressed and bloated before my period, along with crazy migraines for 3-4 days straight. I am unable to lose weight even with running 4 miles a day. I am switching to Lo Loestrin 24 Fe and will try a lower-dosed pill. I have also experienced terrible leg cramps and fatigue like never before."

2 / 10
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  • Anonymous
  • March 18, 2012

For Birth Control "I have been on Safyral for two months, no babies. I used to have heavy periods, but they are lighter now. But I did gain weight, breasts got bigger and very tender. My skin is very broken out, I have a lot of headaches and nausea."

3 / 10
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  • Anonymous
  • September 20, 2011

For Birth Control "I was on Safyral for 4 months. I had breakthrough bleeding the first month, then it stopped (which was very fast for me! It was great). However, my acne increased, and I was tired all the time. Also, I had terribly sore breasts and white vaginal discharge every last week of active pills. My periods became much lighter with fewer cramps. When I stopped taking the pill, my acne was 90% gone the next day! I couldn't believe it! My face looked cleaner than before I started this pill. I was off the pill for a month, and my acne still is very small (which is good because I used to have bad breakouts). A couple of days ago, I started taking LoEstrin 24, we'll see what it does."

5 / 10
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  • Tis...
  • January 19, 2012

For Birth Control "I'm 29 and have been on Safyral for 3 months now for irregular bleeding. I have breast tenderness, bad cramps, acne, and I am also very moody! My anxiety level has raised a little, and the bleeding is heavier than normal. This is also my first time ever taking the pill. This is my last pack I'm taking."

7 / 10
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  • Lex...
  • Taken for 6 months to 1 year
  • January 13, 2017

For Birth Control "This is the only birth control pill that's been effective for me; I tried around 4 other pills before I discovered this one. No breakthrough bleeding (one of the biggest problems I had with the other pills), and it's made my periods so much lighter (I used to bleed through tampons and pads, and now my period is way lighter). I haven't gotten pregnant, so I guess it's also doing what it's supposed to do, lol. Another bonus: I used to get painful cystic acne on my chin whenever it was my time of the month, and since beginning this pill, I haven't had to deal with any acne whatsoever! The only problem I have with it is that I cry a bit more than I used to, but I don't really mind."

8 / 10
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  • Anonymous
  • July 8, 2011

For Birth Control "Was on this pill for 2 months and had extreme mood swings, heavier periods, cramping, and acne. I did not experience any weight gain. This is the 3rd pill I have tried but did not like."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.