Desvenlafaxine User Reviews & Ratings (Page 3)
Brand names: Pristiq
Desvenlafaxine has an average rating of 6.9 out of 10 from a total of 1,384 reviews on Drugs.com. 60% of reviewers reported a positive experience, while 22% reported a negative experience.
Reviews for Desvenlafaxine
- Ret...
- Taken for 1 to 6 months
- November 11, 2014
Desvenlafaxine for Depression "Started 12 weeks ago on 50mg, stuck it out for 7 weeks - not much change and decided to step up to 100mg. 5 weeks later, I can say a change has arrived in the last 10 days and I am over the moon. I have refused medication all my life - this was a massive decision for me. I wish now I'd done it years ago. Critical voice gone, anxiety close to gone, depression lifting, motivation returning - hope and dreams coming back. I now laugh, play jokes, and manage stress 'normally'. I have to take care to get enough sleep - some days I am still really exhausted, but that is lifting. The side effects were as expected: dry mouth, need to eat regularly, headaches, and perhaps a little sleep issues - but compared to life before, they are well worth it."
- Oil...
- Taken for 5 to 10 years
- July 17, 2019
For Anxiety "I've been on Pristiq for anxiety for over half a decade and honestly I think it's great. Sure, it's a bit of a crutch. But I've managed to achieve my university degree, meet, marry and bear children with the love of my life all while under the influence of Pristiq. I was actually prescribed Pristiq due to my anxiety and it has worked a treat. It's worth noting that I am on 200mg a day and every time I get my script filled, the doc has to call up poison control. But it's all good in the hood for me. Just have it with my coffee in the morning and try to get on with my life. I've achieved a lot while on Pristiq and I'm sure it has given me additional confidence and makes me more sexually active, lasting, and sensual. It's been win-win-win for me."
Frequently asked questions
- Gla...
- January 1, 2015
Desvenlafaxine for Depression "Was totally down in the dumps for some reason, even though my life was great. Finally, I could take no more as my mind was giving me nasty thoughts to end things. Immediately went to the doctor, and he prescribed me 50 mg of Pristiq which sent my mind out of control. Now my whole being was in trouble, refusing to go to work and be around my family. Immediately went back to the doctor to be put on 100 mg, and I can say I have never looked back. Totally changed my life as I am myself again. Yeah, a few sexual side effects but I can live with that. I'm just glad to be back."
- Mis...
- Taken for less than 1 month
- January 20, 2015
Desvenlafaxine for Depression "On my first day of Pristiq, I noticed an immediate surge of energy (coupled with a racing heart and a feeling of disorientation). I am somewhat sensitive to medications generally, so I was prepared to experience some of the side effects. What I have experienced in my first week is tiredness, irritability/difficult sleeping, grinding teeth, nausea (vomited 5 times on night 1, which settled on the second day), loss of appetite, and general stiffness around my neck and back. I trust these symptoms will settle in the coming weeks but thought it may be valuable to share my first week, for those who are a little sensitive to medication. In regards to my mental state, I can safely say my mood has been moderately chilled, unfazed, and without any anxiety."
Are you taking this medicine?
Your review helps others make informed decisions.- Jef...
- October 29, 2014
Desvenlafaxine for Depression "I've been on Pristiq for just over a month, and I don't have the desire to do anything. I have gone days without shaving or taking a bath. I feel like a zombie unable to make decisions or take care of myself and my home. I find myself sitting all day on my sofa, and sleeping most of the day. My appetite has increased and now my weight has gone up rapidly. After reading a recent post on this medication, I was shocked to learn that only one other person has had the same experience. I am quitting this medication today."
- meg...
- Taken for 6 months to 1 year
- February 10, 2023
Desvenlafaxine for Depression "Pristiq saved my life. I was suffering from suicidal thoughts, severe anxiety, and depression for 5 months after getting COVID. I tried Lexapro, which was awful for me. After that, I was against taking any other antidepressant, but my mental health continued to decline. I reached out to my provider, who ran a genome test to narrow in on which medications would be best for my body to metabolize. It showed Pristiq and Wellbutrin, so we picked one. Pristiq was the choice, and after bumping it up from 25mg to 50mg, I made a complete recovery with my mental health. I have been on it for 9 months and am now going to start to taper off. If my mental health starts to decline again, I will 100% be using Pristiq again. Hope this helps someone!"
- Anonymous
- March 1, 2009
Desvenlafaxine for Depression "I will start by saying that I suffer from major depression. I have tried just about everything in the book and was starting to just about feel like giving up hope (on medications, that is!) and was completely exhausted. My doctor just recently put me on Pristiq, and almost immediately I noticed a difference and have had no side effects whatsoever. I have been excited about life and happy to get out of bed every day now. It has been a drastic change, and I am so thankful. I'm not sure how this medicine might affect others, but for me, it has worked wonders."
- dva...
- December 10, 2009
Desvenlafaxine for Depression "For those coming off antidepressants such as Wellbutrin, Lexapro, and Zoloft. The venlafaxine formulation in Effexor and Pristiq work in entirely different ways than the medicine you used to take. If you cut cold from your old drug, you will also have withdrawal symptoms despite having started on a new antidepressant. If you are coming off something you've been taking longer than 5 months, ask your doctor to wean you off with smaller and smaller doses first. Lexapro, Zoloft, Celexa, and Prozac are SSRIs. Wellbutrin (bupropion also marketed as Zyban) is an NDRI. Effexor, Pristiq, like Cymbalta, are all SNRIs. They all go after different receptors in your brain, and some of them change how your brain works."
- amy...
- July 26, 2014
Desvenlafaxine for Depression "I've been taking 50 mg Pristiq in combination with 300 mg Wellbutrin for two weeks, and it's the best I've tried. This week I've been able to handle family and work issues with a sense of hope and able to focus rather than anxiety/worrying, and that's awesome. I had been taking Prozac and Wellbutrin for years but felt it wasn't working. I tried everything but other meds didn't work or had bad side effects. This made me queasy at first, but my Dr. had said that would get better, and it did. I take it at night because in the morning, it makes me tired. So don't give up! There is hope. Hang in there."
- Ga ...
- Taken for less than 1 month
- May 27, 2014
Desvenlafaxine for Depression "Been off and on antidepressants for 20 years. Been on 100 mg of Zoloft for about 5 years now and was having some adverse effects - gained a lot of weight for starters. Started Pristiq about 3 weeks ago. I feel a lot clearer in the mind - guess I didn't realize the fog I was in on the Zoloft. I'm not hungry - lost seven pounds in the first two weeks. Had some headaches while switching over. Sleep hasn't been a problem - but I have found that I need to take the meds at the same time in the mornings or I have headaches. So far, so good. Hopefully it will continue long term. I will probably be on meds the rest of my life - I've come to terms with that. Hoping this will be the last one I'm on!"
- Anonymous
- August 28, 2008
Desvenlafaxine for Depression "I have been on Pristiq for about 2 months. I've tried probably 10-12 other antidepressants with lots of side effects that made me want to quit them. I feel better emotionally today. I have no side effects and I am able to complete tasks in a reasonable amount of time, without feeling overwhelmed. I have no anxiety issues and I am finally enjoying my life. I only wish the insurance industry would cover this medication."
- Ros...
- Taken for 1 to 6 months
- June 12, 2024
Desvenlafaxine for Depression "I started on 25 mg of Pristiq in March and just upped my dose to 50 mg 2 weeks ago, so I’ve been on this medication about 3 months. After bad experiences with other antidepressants, I took the genesight test (100% recommend everyone do this) and Pristiq came back as the top match for me. I would say that my big fears (phobias, existentialism, etc.) have decreased significantly and I no longer have extremely dark thoughts about whether I’m meant to exist. In all, I’d say my anxiety, OCD, and depression have been improved about 30-40%. Side effects aren’t bad, but I do have fatigue and dropping elevator/dizzy sensations regularly. Nothing compared to side effects I had before though! Just make sure you eat enough and drink lots of water. Also, meditate! Generally happy with it overall and am hoping it gets better as I’m on it for longer. Hope the best for everyone out there! Keep your head up!"
- Jay...
- Taken for less than 1 month
- July 11, 2019
For Anxiety "Before I began this medication, I had terrible anxiety. I was barely functioning. I am currently on day 13 and I really started to notice a difference on day 10. They say it takes months for symptoms of depression to improve but this works pretty quickly for anxiety. The side effects I am experiencing are constipation and brain fog. Hopefully, that lets up, but I am feeling much better without being constantly anxious. My anxiety has gone from a 10 down to a 2 on a 1-10 scale."
- WCa...
- Taken for 1 to 6 months
- February 25, 2013
Desvenlafaxine for Depression "Best medication EVER! After 2 years of feeling angry and upset and constantly fighting with my husband (over stupid things) and having suicidal and self-harm thoughts purely from severe depression, I am now feeling 100% absolutely fantastic ALL the time thanks to Pristiq! Before, I could barely get out of bed. Now I have heaps of energy to last all day and am constantly on the go. I LOVE how this medication makes me feel. I'd highly recommend trying this antidepressant."
- Ano...
- April 11, 2016
Desvenlafaxine for Depression "Absolutely no side effects. I lost weight on this medication, however, if you do not want to lose weight, talk to your psychiatrist, and they can prescribe medications that can help you gain weight if you are underweight. This medication worked perfectly on my depression, and I have not relapsed since I was weaned off it. No sexual side effects, it actually helped my sex life. I am so happy I tried it."
- Jo ...
- November 22, 2013
Desvenlafaxine for Depression "Have been taking Pristiq for just over a month -- relief from anxiety and depression after 3 days and able to concentrate and focus again to full capacity -- no side effects and sleeping well. I was on Effexor on and off for 10 years, with not a lot of relief from anxiety symptoms. Have lost some weight as well, and am starting to feel very positive."
- m21...
- Taken for 1 to 6 months
- September 4, 2024
Desvenlafaxine for Depression "This medication is positively incredible. I was in an absolutely terrible place a few months ago. I had a breakdown and was barely functioning. I started Pristiq 50 mg 7 1/2 weeks ago. I know it works immediately for some people, but it took some time to kick in, so please be patient if you're not feeling the effects right away. I started to feel a bit better at week 4, and by week 6, I felt like an entirely new person. I am happy, productive, and able to be sociable, exercising regularly and feeling very good. I was really scared to start taking this. I know that it's not easy to come off, and that worries me, but I knew I had to do something, and if I have to take this for the rest of my life, I'm okay with that. It's well worth it... I went from being practically unable to function to feeling almost 100% within 6 weeks. If you've tried other meds with no success, Pristiq is worth a shot."
- Bpa...
- Taken for 1 to 6 months
- November 16, 2023
Desvenlafaxine "Listen guys, it has been a serious battle dealing with depression and panic disorder. I almost lost everything over the course of 8 years. Struggling to go outside, keep friends, make friends, keep a job, work a job... everything... even going into stores. But this medicine at 50mg for only about 2 months now has completely changed that. I mean, seriously guys, it's no joke. First day I was on a cloud, felt at peace. Second day and over the next week it leveled out and I felt in control for the first time in years. The only side effects for me were dry mouth and insomnia, both went away during the first week. This medicine really does work, please don't be scared. We got this!"
- Eve...
- Taken for 1 to 6 months
- March 29, 2023
Desvenlafaxine for Anxiety "I started taking Pristiq for anxiety and agoraphobia, and it really helped me! However, it took a long time to kick in, but I’m so glad I stuck with it. I started on 50mg, and after 8 weeks, I honestly didn’t feel much different. I thought this wasn’t going to work, then we bumped up to 100mg, and that’s been the sweet spot for me! I just feel so, so much better in daily life. I’m able to attend social gatherings and visit restaurants without having full-on panic attacks and being absolutely consumed by anxiety. It’s been about 6 months now, and I just feel so much less scared of the world. My only side effect is being way more constipated than I used to be, but I’m working on this because I don’t want to go off Pristiq anytime soon. Give it a try and see if it works for you because it’s really changed my life!"
- Pri...
- March 21, 2009
Desvenlafaxine for Depression "I've been on Pristiq for 8 weeks and believe me, I have never felt better in my life. It works, no side effects. I'm a happy person now. The only thing I wouldn't do is to take Pristiq at night time. I take it at 8:00 am, so I don't have sleeping problems. Try it this way. This medicine is wonderful. GOOD LUCK EVERYBODY."
- Coo...
- June 7, 2015
Desvenlafaxine for Depression "My doctor put me on 100 mg once in the morning, and I could tell a huge difference in the way I felt. For the first time, I felt like I could breathe, I could see colors again, the trees, the flowers, everything changed from grey to vivid brightness, however, this effect was not immediate. I was taking 120 mg of Cymbalta, 2 60 mg caps a day, when this was the medicine I was on for years. I fought a good fight with doctors over years and years. They were telling me I was bipolar and I believed them. It took one great doctor 15 minutes to change my life. I have been on Pristiq 100 mg for going on 3 years now, and I love life again. I can't wait to wake up early in the morning and watch the sunrise, and I found out that I wasn't bipolar."
- Ama...
- December 3, 2014
Desvenlafaxine for Depression "Finally I see hope. After being diagnosed with severe depression (took me 4 years to seek treatment), I tried 5 different medications (plus therapy). They all failed miserably and I lost the hope I didn't even know I had, then tried suicide twice. Finally I was prescribed Pristiq and let me just say... what a difference! It got easier to wake up and get through the day, my self-esteem got better, my anxiety doesn't come as often, and I can even make plans for the future. For the first time I see change is possible. Just don't ever forget to take your pills, you can't really function without them. I got no side effects except for increased hunger/libido, and a bit of difficulty falling asleep. I'm taking 150mg now."
- Kev...
- January 23, 2014
Desvenlafaxine for Depression "Went to the doctor complaining of anxiety. Was waking up and not falling back asleep or even worse, could not fall asleep. Was also having anxiety attacks. The last time this happened, I was prescribed Effexor, which was a nightmare, and Celexa, which did nothing for me. Ended up quitting my job and with time off, I returned to normal. Quitting my job this time is not an option, so the doctor put me on Pristiq. Noticed a positive effect within 7 days, and I have been on it for a month now. This drug has worked absolute wonders for me. I have had no side effects at all (and no sexual impotency)."
- Kay...
- Taken for 1 to 6 months
- February 19, 2020
Desvenlafaxine for Depression "Had a DNA test to recommend what type of antidepressant I should be taking. I had been on Venlafaxine for years after refusing others. Pristiq was recommended by this test for me to take. I did notice a number of positive changes taking Pristiq. Generic 'Desvenlafax.' I am more alert, have somewhat more interest in life. No longer think about dying. It doesn't control my anxiety, so therefore I take a mild dose of Klonopin when needed. It did not give me energy but helps me get up and around. I take 50 mg a day. I do sleep 10 to 12 hours a day, sometimes not waking up during that time, but I know that's the depression. I do take Amitriptyline for pain from Spinal Disk Degeneration pain."
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Desvenlafaxine for Major Depressive Disorder "I had been on numerous meds that weren't helping. Horrible anxiety and depression. Extremely irritable. I decided to try Pristiq anyway, and within an hour, this sense of calm rushed over me. I felt so at peace. I'm more alert. I don't need constant naps. I'm positive, and life is great. At first, though, insomnia sucked, but every night it improved and didn't last long. I'm sleeping great now. It's been a few weeks, and I'm still struggling with constipation. I had headaches at first too, but not anymore. It has destroyed my appetite, though. I can miss my dose by hours and not experience the 'brain zaps' or feel any different at all, unlike others. I feel absolutely amazing, and it has by far boosted my marriage more than I could ever imagine. I can even see the spirits of my kids lifted immensely. I don't obsess over things like before, and I'm more relaxed. I've had no sexual side effects, I can still orgasm, and I've actually been more in the mood because I feel better."