Denosumab and Back Pain: What Users Say (Page 2)

• AW ...
• December 17, 2016

Denosumab for Hypercalcemia of Malignancy "I have lung cancer with mets to bone. Two hours after the injection, I experienced the worst pain ever in my life! I walked into the infusion area without any body pain, just a very slight backache which Advil was helping, and 2 hours later I was crippled. It's 2 weeks now, and I'm either in a wheelchair or walking around the house with a cane. Horrible, horrible medication. I now take oxycontin every 12 hours and oxycodone every 3 hours. Refuse this drug if you are smart. Even my oncologist is 'surprised' with the side effects I have. I refuse to have a second injection of Xgeva."

• mar...
• Taken for 6 months to 1 year
• April 4, 2018

Denosumab for Osteoporosis "I received my first Prolia injection in June 2017 and the second injection on December 19, 2017. I did experience back, hip, and jaw pain with the first; however, it has been much worse after the second. I’m taking six Advil per day with little relief. The pain is interfering with activity at work, home, etc. I will have to talk to my nurse practitioner. My bone density has improved; however, due to the pain, I wish I had not taken the medication."

• Umm...
• Taken for less than 1 month
• July 9, 2021

Denosumab for Osteoporosis "After my first dose of Prolia, I've had horrible back pain. I tried calling my doctor's office to ask about how long this side effect usually lasts. Of course, I haven't received a call back. I'm worried about reading that a person has to stay on this forever. I can't imagine taking this again. In my opinion, this medication should come with a consent form showing the side effects. I honestly believe this drug has poisoned my body."

• Chi...
• Taken for less than 1 month
• January 17, 2021

Denosumab for Osteoporosis "I had the worst experience ever. I had angioedema of the face, and almost 2 years later I am still having bouts of adverse events. Stomach issues, the right side of my face and ear seem to develop similar symptoms of angioedema but very light, severe back pain, my asthma has issues since the drug. These are just a few."

• Pam...
• Taken for 6 months to 1 year
• December 30, 2021

Denosumab for Osteoporosis "I had the Prolia injection once, and within a few days, my hair started falling out until I was nearly bald and needed wigs. Rashes came out all over my body, restless leg syndrome, backache, indigestion, which I had never suffered from, lumps all over my skin, and psoriasis, of which I had small patches that took off like mad. I would recommend anyone about to take this drug to seriously consider the side effects before having it. It is too late afterwards, as many side effects never go away. I referred to it as a poison."

• San...
• Taken for 1 to 6 months
• March 6, 2022

Denosumab for Osteoporosis "I received the Prolia shot 12/29/22. Eight days later, I started having all the side effects, my arms, legs, back, muscles, and joints hurt. 3/4/22, I had an appointment at the hair salon. I was told that I was losing hair. After shampooing, I was given the hair that fell out. I was told by the hair salon not to take any more Prolia shots and to call my doctor regarding all the side effects that I had endured. Prolia should be taken off the market."

• Gin...
• Taken for 1 to 6 months
• January 25, 2022

Denosumab for Osteoporosis "Wow, wish I had looked at reviews before taking this Prolia injection for osteoporosis! I have taken Fosamax years ago, but was tired of staying upright for 1 hour, and then I began thyroid meds. Fosamax did help, but the femur fxs were happening with prolonged use. My scan showed better in lumbar spine, worse in hips. So in Nov. 2021, I took the Prolia shot. The nurse said people have said they can experience lower back pain. Well, do tell, I can relate to these reviews with central low back pains and understand other issues from your reviews. Thank you for convincing me not to continue the shots. I certainly wish all of you can regain your peaceful selves again."

• Deb...
• July 1, 2021

Denosumab for Osteoporosis "I’ve had 4 Prolia injections. I have constant pain in my hips and lower back. My bones ache, some days I struggle to walk. Told my oncologist I won’t be having another injection. Said to talk to my GP. GP said talk to your cancer doctor. Still don’t know what happens once I stop taking this drug. Time will tell."

• Jan...
• Taken for 1 to 6 months
• November 18, 2021

Denosumab for Osteoporosis "Back, arm, and shoulder pain started within two days of getting the Prolia injection. Six months later, and the pain is still there. Working with a physical therapist and doctor has been putting pain med injections in my shoulder. This is all after only one injection. None of this pain was present at all before the injection. This has been a miserable experience!"

• 322...
• Taken for 6 months to 1 year
• October 3, 2021

Denosumab for Osteoporosis "I had the first injection in December and had increased back pain, but otherwise it seemed to be okay. I got my second injection in the middle of June, and by the middle of July, I couldn’t get out of bed because of SEVERE back pain. At the same time, I started having severe esophageal pain and nausea. My muscles in my chest hurt. I had and still have severe constipation. My hands hurt all the time and have no strength in them. I’m so tired all the time and becoming depressed. The endocrinologist said she has been giving this drug for 11 years and NONE of her patients have ever had a reaction. The way the procedure (injection, lab one week, see doctor two weeks) made me feel like I was just one more in the assembly line! I’m beginning to think the doctors must get a big kickback from the drug company to be pushing this drug so much. I will not take this drug again, and the endocrinologist said I didn’t need to return to see her! I’m just going to take calcium and D3 and hope for the best."

• 322...
• Taken for 6 months to 1 year
• October 3, 2021

Denosumab for Osteoporosis "I had the first injection in December and had increased back pain, but otherwise it seemed to be okay. I got my second injection in the middle of June, and by the middle of July, I couldn’t get out of bed because of SEVERE back pain. At the same time, I started having severe esophageal pain and nausea. My muscles in my chest hurt. I had and still have severe constipation. My hands hurt all the time and have no strength in them. I’m so tired all the time and becoming depressed. The endocrinologist said she has been giving this drug for 11 years and NONE of her patients have ever had a reaction. The way the procedure (injection, lab one week, see doctor two weeks) made me feel like I was just one more in the assembly line! I’m beginning to think the doctors must get a big kickback from the drug company to be pushing this drug so much. I will not take this drug again, and the endocrinologist said I didn’t need to return to see her! I’m just going to take calcium and D3 and hope for the best."

• Suf...
• Taken for 1 to 6 months
• August 1, 2021

Denosumab for Osteoporosis "The day after having the Prolia injection, I developed a 3-day headache, followed by chronic fatigue and vertigo. A week later, all my joints-neck, shoulders, elbows, wrists, hips, knees, and ankles-all started cracking. In the third week, I developed sciatica on my right side. I was unable to sit, I could only stand, walk, or lay flat. Sitting was unbearably painful. I have been medicated with Tramadol for pain. I have tried acupuncture, therapeutic massage, and hot mineral springs. Nothing has helped. I take natural vitamin supplements and calcium, nothing helps. I have read that Prolia weakens the immune system, so there is no way I would ever have the Covid vaccine in my situation. My body is very compromised. I would caution anyone considering Prolia. I had no ill health symptoms before I had this, and now I’m incapacitated."

• San...
• Taken for 5 to 10 years
• November 12, 2021

Denosumab for Osteoporosis "I have been having Prolia injections for the past 5 years. I suffer most of the common side effects related to this drug, particularly severe back pain and bone pain, which seems to get worse the longer I am on it. It is particularly bad at night, so it affects my sleep. On the plus side, a recent bone density scan showed my T score had gone down from -3.1 to -1.8, putting me from the osteoporosis diagnosis to osteopenia. Has it been worthwhile? I don't know. What frightens me is the warning that it should not be stopped, as the spine is likely to fracture within 7 months. None of this was explained to me before I started having the injections. It does work, but at a high price."

• Anonymous
• Taken for 6 months to 1 year
• June 12, 2012

For Osteolytic Bone Metastases of Solid Tumors "I have breast cancer with metastasis to the bone. Prior to taking denosumab, I was receiving Zometa, approximately 2 years on a monthly basis. One positive element is that this is being given subcutaneously, saving my veins, also, it is not so hard on my kidneys. I do experience itching and back pain, but this only lasts about 1 week after the subcut. I have been receiving the injections approximately 6 months, every month. I also take Aromasin and was diagnosed in April of 2007. My tumor marker is low at 22, remains at that number after making the switch from Zometa to denosumab."

• Lui...
• Taken for less than 1 month
• September 15, 2020

Denosumab for Osteoporosis "Prolia has given back pain so that it feels like it is going to break. Pains in my arms, legs, and hands."

• Nic...
• March 8, 2016

Denosumab for Osteoporosis "Headaches, lower back pain, visual problems, increased reflux, foot swelling, fatigue"

• 177...
• Taken for less than 1 month
• January 15, 2018

Denosumab for Osteoporosis "Great fatigue and back pain. I doubt I'll do the second shot. Sad as I thought this would help. I have osteopenia, so hopefully, there's something else."

• Ros...
• Taken for 6 months to 1 year
• August 21, 2022

Denosumab for Osteoporosis "This is my 2nd injection. I do have more fatigue, and my back and arm pain is terrible! I hope it gets better."

• Suz...
• Taken for less than 1 month
• November 17, 2021

Denosumab for Osteoporosis "How long does back pain last after getting the Prolia shot? Mom just got her 1st Prolia shot, and she has terrible back pain. Do you know how long she will have to deal with back pain side effects?"