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User Reviews for Dalfampridine

Also known as: Ampyra

Condition Avg. Rating Reviews Compare
Multiple Sclerosis  
8.0
71 reviews 98 medications

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Dalfampridine

Andr · Taken for 5 to 10 years September 26, 2020

For Multiple Sclerosis: “I wanted to know if other people were experiencing the same as me. And then I found these reviews, with one person saying that the Mylan version is like the original, and the Ascend version is garbage. I looked at what Kroger provided me and was not surprised to see that they gave me the Ascend version. If I'm unable to convince Kroger to provide me with a different manufacturer return to the compounded version although it's almost twice as expensive.”

2 / 10
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Bea June 13, 2020

For Multiple Sclerosis: “I’ve been on it since April 14th has not helped walking feels worse more of a limp then before ”

2 / 10
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Stephanie · Taken for 6 months to 1 year June 3, 2020

Ampyra (dalfampridine) for Multiple Sclerosis: “I was excited to start Amprya..was hopeful..but it did not help me whatsoever.;(”

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glen0218 March 30, 2010

Ampyra (dalfampridine) for Multiple Sclerosis: “For eight years now, I've been on 4-aminopyridine ER, the chemical name for dalfampridine, and am now on Ampyra. I was able to obtain 4-AP from a compounding pharmacy by prescription. I have been astounded by the change this chemical has made in me, and, through physical therapy and exercise, by what I have been able to gain because of it. The primary improvement for me has been leg strength, but I've also noticed some improvement in breathing, eyesight, balance and cognition, though I find no documentation to support my observations on these latter four. When I go off of the drug, these improvements vanish until I start up again. I've gone from power chair to forearm crutches to hiking again! Wow!!”

10 / 10
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Anonymous June 1, 2010

Ampyra (dalfampridine) for Multiple Sclerosis: “I have used almost every medication known to man for primary progressive MS. Understanding that this is not a cure but, the improvement in my mobility is amazing. I still lack a large range of motion. But, going to the gym now (which I could not do before) hoping to rebuild and retrain muscle that I have not used in years. I'm not 100% but, I am way better than I was before and I'll take back what I can get back. A little before the time to take my second dose I tend to start return to the state I was at before I started taking it. Second dose and I'm back up ready to face the world feet first. This has given me so much hope after I have been disappointed numerous times before.”

9 / 10
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national champs · Taken for 1 to 6 months September 10, 2013

Ampyra (dalfampridine) for Multiple Sclerosis: “Ampyra has been a Godsend for me! Before I started taking it, I was a "wall-walker". I always had to hold onto a wall before I took a step. Now I am walking without assistance. I saw improvement after my second dose. Now I am exercising again which makes me feel so much better-mentally and physically. I was 51 before I was diagnosed and not being able to walk made my life miserable. Now, I feel like I am more of a "normal" person than I have been in 20 years! Thanks Ampyra!”

10 / 10
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Anonymous · Taken for 1 to 2 years December 22, 2012

Ampyra (dalfampridine) for Multiple Sclerosis: “I have been taking this medicine for a year now, and it works great for me. I have relapsing-remitting MS, and I experience balance and coordination issues while walking (among other things). The FIRST time I took this (10mg extended release tablet) I noticed an immediate improvement in my ability to walk. All of a sudden, I was dashing up the stairs, which normally gave me trouble. I'm able to walk most of the time without my cane now! I have also noticed better bladder control. I know it is not a cure, but it greatly helps my MS symptoms. Ampyra has been a great blessing.”

10 / 10
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MonsterSlayer · Taken for 1 to 2 years February 20, 2014

Ampyra (dalfampridine) for Multiple Sclerosis: “Doctor said I was headed for a wheelchair but now I hardly get asked 'what happened to your foot?' . If I concentrate while I'm walking, I can almost look like nothing is even wrong. Plus, I haven't fallen in over 6 months.”

10 / 10
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Djlillz January 16, 2013

Ampyra (dalfampridine) for Multiple Sclerosis: “I started Ampyra five weeks ago. The first full day I was miserable with nausea but over the next few days the nausea lessened. Three weeks into taking it I realized that I wasn't tripping anymore and my right leg footdrop was all but gone. Now I'm trying to strengthen my leg muscles and walking on the treadmill and riding the exercise bike everyday. I've had RRMS for 17 years. Four years ago I was easily walking three miles a day without any problems, but over those last few years I was weakening, tripping, falling. I couldn't even walk a half mile. I was in a leg brace and using a cane frequently. Just seeing a set of stairs I was going to have to climb put me "over the edge". Now I'm going up the stairs and starting to walk much better.”

10 / 10
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Anonymous April 25, 2010

Ampyra (dalfampridine) for Multiple Sclerosis: “Not a cure and I may have been expecting (hoping for) more, but it's working for me. I still use a cane to walk to the office (.33 mile), but I now get around the office without the cane, including going to the restroom, going for lunch, etc.”

8 / 10
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aCHILLD January 3, 2015

Ampyra (dalfampridine) for Multiple Sclerosis: “I was diagnosed with Multiple Sclerosis in 1988. Since I started taking AMPYRA (8/2013), I have experienced marked improvement in cognition, speech, diaphragm and core muscle strength. These gains were accomplished with the help of P.T. and O.T. professionals and continuous improvement efforts on my part (range of motion and exercise). Benchmarking and goal setting has helped me recognize the drastic changes taking place. Specifically, hand and finger dexterity, arm and shoulder range of motion, trunk stability, legs, feet and overall muscle regeneration after years of chronic deconditioning. The results are readily apparent to my Physicians, family, care team, friends.”

9 / 10
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Mommy April 4, 2020

Ampyra (dalfampridine) for Multiple Sclerosis: “I was diagnosed with RRMS in 2014 and the main sign that sent me to the doctor was my weakness in my legs. I recently found an amazing Neurologist who finally agreed that I did have loss of feeling and weakness in my legs. He put me on Ampyra for four weeks to see if it made a difference for me. Well, today it has been 30 hours since I have had my last dose and while trying to shop this morning I almost cried. The difference was amazing for me. While I has on it I didn't have to use the handrail and push on my legs to walk up the stairs. It was so much easier for me to get up from sitting, get in and out of my car and my balance improved so much. Hopefully I can get ahold of my doctor to get back on this soon! He told me to wait four weeks but I don't think I can wait that long. It's definitely worth trying if you have legs problems! The only side effect I had was constipation, but I changed my diet and eventually had no issues. ”

10 / 10
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Nikman April 20, 2013

Ampyra (dalfampridine) for Multiple Sclerosis: “RRMS for 3 years. Started Amphrya 1 week ago and saw results on first day! Truly amazing that I can feel all the way to my toes in my weaker left leg! I am so encouraged by this pill. I have had absolutely no side effects. Still only taking 1 pill per day since its been only 1 week. Please give this a try, I wish I would have and not waited 3 years.”

10 / 10
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JimDadTwo · Taken for less than 1 month June 10, 2013

Ampyra (dalfampridine) for Multiple Sclerosis: “Was having increasing difficulty with my left leg (drop foot, dragging, fatigue especially when on hills) and my left arm (typing characters out of order, weakness). Yes, I have Multiple Sclerosis. Took my first dose 3 days ago. Began to feel improvement within two doses, but thought it was a placebo effect. By the next day was I walking hills with ease, only muscle soreness (after) and a bit winded (during), but none of the neurological issues! I could also feel the medicine's effect begin to diminish about the 10th hour after a dose.”

10 / 10
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YLGram October 19, 2013

Ampyra (dalfampridine) for Multiple Sclerosis: “This med is a wonder drug for me. I saw a difference in my walking speed w/in 2 weeks with only the 10mg use. As I moved up to the full 20mg daily I found I had more energy, didn't need my daily nap and even have done some light gardening. Last night I walked down a 3 story spiral staircase when leaving a concert (holding on to the rail and holding hands with my husband). My ONY negative is with the "Speciality" pharma which we are forced to use. (No choice they are the only pharma for this med.) Accredo is enough of a hassle (even for my MS renowned DR), I may stop if I have to deal with them monthly. Don't be afraid of the seizures warning in the info. W/ the time release pill it seems not to be an issue if take correctly.”

10 / 10
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Junae · Taken for 2 to 5 years January 28, 2015

Ampyra (dalfampridine) for Multiple Sclerosis: “I have been diagnosed with Multiple Sclerosis for 17 years. I started Ampyra 3 years ago and since then I am more stable. I walk a little bit faster and get a lot more done in a day. Right after I started Ampyra I was able to snowboard with my kids, something I never thought would have been possible.”

9 / 10
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stella rondo · Taken for 2 to 5 years February 20, 2013

Ampyra (dalfampridine) for Multiple Sclerosis: “I have had some minor side effects but nothing serious. I used to use a foot brace and cane, but once the medicine kicked in I put them both away and haven't needed them since. This medicine is a God send, and I hope it will work for you too.”

10 / 10
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AnneKilleenTX September 16, 2016

Ampyra (dalfampridine) for Multiple Sclerosis: “MS since 2002- 58 year old with poor balance , weak right leg and foot drop, I use brace, rollator and wheelchair. Started Ampyra 6 days ago, the first 3 days or so I was mildly lightheaded and it seemed the neuropathy in my legs was increased, but I was also feeling sensations I haven't felt in long time! Day 4 I felt a surge of energy and was all over the house. Today day 6th I was able to walk more than I have in years without crying of exaustion or my legs giving out, legs so much stronger! I am beyond exited that this is all happening so fast and very happy I got brave enough to try Ampyra. And yes around the 11th hour you know when medication is wearing off, so if you start Ampyra carry pills with you :). Good luck!”

10 / 10
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SallyM August 1, 2010

Ampyra (dalfampridine) for Multiple Sclerosis: “I have been on Ampyra for 5 days and have been so happy with this new pill. The first 2 days were NOT good with the side effects, but each day just gets better. I am able to walk better (without dragging my left foot) and get up from a kneeling position without to much effort. This new medicine has given me a new outlook on my future. Thank you for this medical wonder!”

9 / 10
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megaw · Taken for 2 to 5 years May 9, 2015

Ampyra (dalfampridine) for Multiple Sclerosis: “I was diagnosed with MS 2006. I found myself with a loss of balance. I fell so much at my work I gave my co workers at the gym score card as to how I fell. I have a sense of humor which helps me get through this new found life. My dr told me about ampyra after I started taking this drug my falls decreased. We haven't had to score any of my falls in over a year.”

9 / 10
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pixietwin · Taken for 1 to 6 months January 4, 2017

Ampyra (dalfampridine) for Multiple Sclerosis: “Ampyra is a MIRACLE for me. I have been on one pill a day for exactly one month. I have had MS symptoms since 2005 but was not diagnosed and put on Copaxone until last year. I have experienced two years of extremely heavy legs while just standing for more than 15 minutes, expecially my left leg. My life had changed dramatically. Having to use a rollator when I left the house. My neuro finally prescribed Ampyra after asking for the last two years. After two weeks, I noticed that my stamina was much better. At one month, I could not believe it! No more heavy legs at all. I could stand and do housework for more than an hour. No side effects. I take one pill about 10 a.m. It runs $40 for a 30 day supply. Wonderful pill so far”

10 / 10
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Dort September 21, 2010

Ampyra (dalfampridine) for Multiple Sclerosis: “I have taken AMPYRA for 1 month. The second day I thought it was my imagination but I did things I couldn't do before, like stand at the sink without leaning, lifting my legs much higher. My left arm was weak and almost always had a closed fist, not anymore. I can actually use the key board again with both hands. So much more to say, it is a miracle medicine. To bad, my insurance denied another month. Just purchased 15 day supply on my own ($592.50) while I fight the denial. Everyone should give it a try. ”

9 / 10
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Mo Lilac April 26, 2017

Ampyra (dalfampridine) for Multiple Sclerosis: “I was diagnosed with MS in August 2016. I am a dance instructor, and noticed that I was limping, especially after class. I had foot drop, numbness, Charlie horses and cramping at night. I have 2 small children who keep me active as well. MS totally changed my quality of life. I am taking Copaxone 3 times a week, but it doesn't help with the symptoms. I read about Ampyra, and because my main gripe about MS is the way I walk, I decided to ask my Neurologist if I could try it. I've been on it for a week and already notice a difference. I'm hoping with time that it'll do more for me. I chased my son around the park this weekend and noticed a huge difference when I taught class yesterday. Very glad I tried it!”

10 / 10
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MsOllie · Taken for less than 1 month January 2, 2016

Ampyra (dalfampridine) for Multiple Sclerosis: “Ampyra is the only drug that has been helpful to me with the exception of Tysabri which I was forced to quit. I have been diagnosed with MS for over 10 years and have gone from RRMS to SPMS over the past three years or so. I read about Ampyra a number of years ago but was afraid to try it because of all the side effects. I wish I had tried it along time ago! I used to walk hugging the wall for balance and sometimes used a cane. I have only been on it for two weeks now and my balance is hundred percent better. I do not use the wall at all. I also have a left arm that wants to contract up so that it I hold it in front of my abdomen. I have noticed in the last day or so that my arm no hangs almost straight. Don't be afraid, try it!”

10 / 10
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TheTurtle · Taken for less than 1 month December 15, 2019

Ampyra (dalfampridine) for Multiple Sclerosis: “THIS. DRUG. WORKS! Originally diagnosed with RRMS in 2016, then PPMS in 2019 my walking and balance had degraded to requiring a cane at all times. Further, my stamina became non-existent. During a drive to see family after my first two doses, I had to pull over to, ahem, answer the call of nature. I walked unaided down into and back out of a ditch. I thought only about watching my step. I didn't fall or falter. Later that evening, I walked nearly half a mile with out stumbling or bracing myself once. I carried my cane, but did not use it. I do not know if my improvement will continue or if this is as far as I can go. Either way, I tremendously happy with the efficacy of the drug and will keep taking it for as long as I can.”

9 / 10
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Anonymous November 11, 2011

Ampyra (dalfampridine) for Multiple Sclerosis: “I have had amazing results with Ampyra. I was relying on a walker more and more often because of leg weakness. Within two days of starting the medication; I was back to a cane and not even full time. After two weeks; I can now stand on my own for 4-5 minutes and can walk much faster without foot drop. The only reason I didn't give it a 10 out of 10 is because of mild side effects (nausea and headache).”

9 / 10
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Ezmerleda9 July 27, 2011

Ampyra (dalfampridine) for Multiple Sclerosis: “Ampyra has made my quality of life a more positive experience! I used to have problems with my gait, Ampyra makes it so I am able to walk straight again. Also, I have noticed a drastic change in my cognitive functions. My thought process, language barrier and my ability to remember things short term has improved. I can really tell a difference if I forget a dose! Not a cure, but a step in the right direction!”

10 / 10
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PositivelyMS · Taken for less than 1 month January 22, 2013

Ampyra (dalfampridine) for Multiple Sclerosis: “I have been on Ampyra for 4 days and I can't remember the last time I felt this good. Left leg is working better, can stand for longer periods of time, and I think that is just the beginning. Like others, I am going to start retraining my body to get back to normal as much as I can. Going back to Mayo tomorrow to have strength retested for before and after. I am part of a study going on. Drug company is contributing to keep my copay to a minimum.”

9 / 10
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This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.