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Colchicine User Reviews & Ratings (Page 2)

Brand names: Colcrys, Mitigare, Lodoco, Gloperba, Colcigel Gel

Colchicine has an average rating of 7.3 out of 10 from a total of 102 reviews on Drugs.com. 64% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Colchicine

Commonly mentioned side effects
  • Pat...
  • August 23, 2016

For Gout, Acute "This only works at the onset of an attack. I used it on my third attack, when I felt the tingle in my big toe. I took 2 immediately and 4 more for every hour after. It controlled it overnight and I am almost pain-free the next day. What causes the pain is the crystals; so colchicine is not a pain reliever. What it does is reduce the amount of white blood cells attacking the site, thus lowering the swelling and associated pain from it. Used in conjunction with Naproxen, I avoided my 3rd attack."

10 / 10
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17 Report
  • Cod...
  • Taken for 1 to 2 years
  • October 4, 2013

Colchicine for Gout, Acute "I get about 2-3 flare-ups per year, always on the side of my big toe(s). Dr. prescribed Colcrys 0.6 mg - I honestly don't get any relief that I can tell from this medication. I take 1 every hour for a max of 3 pills over 3 hours... Seems like the ONLY relief I can get is by flushing my body with tons of water - which can take 3-4 days."

2 / 10
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24 Report
  • Fre...
  • Taken for 1 to 6 months
  • June 5, 2013

Colchicine for Gout, Acute "Have been on Uloric for 4 months. Getting flare-ups in knee (which Doc says will go away in another month or so). Colcrys has terrible side effects but gets the job done on the pain immediately. Is a trade-off I have to make for a while."

10 / 10
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19 Report

Frequently asked questions

  • Mem...
  • April 23, 2016

For Gout, Acute "Excellent saved my life and sanity. Had gout for 5 weeks in severe pain between 7-11 on a scale of 10. Kept improving slightly then flaring up. Couldn't wear shoes! Have used it now for 5 days and almost all gone! Best with Voltaren. This is my first gout attack. Also, having it with meals stops the sickly feeling. Only slight loose stools."

10 / 10
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14 Report
  • nig...
  • March 5, 2013

For Gout, Prophylaxis "Had 2 bouts in left big toe. Second one was so bad couldn't use the clutch in the car or change gears on the bike. On a bad day, I considered a chisel and mallet, but about a week after starting colchicine, I woke to find pain reduced by 50%, and within about 3 weeks, 95%, so well pleased and no apparent symptoms."

7 / 10
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17 Report

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  • MAR...
  • Taken for less than 1 month
  • May 7, 2016

For Gout, Acute "Have had gout attacks since 1986, back the heavy beer drinker. Quit drinking in 1997 and gout attacks down 80%. Now 60 years old, I occasionally get gout attacks, but I take allopurinol 325 daily. Has been great, but recently had some medium pain in joints, so I'm back on colchicine .06 daily, feeling better. Gotta stay away from greasy meats, shellfish, but medication works great."

9 / 10
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15 Report
  • Gou...
  • Taken for less than 1 month
  • October 25, 2022

For Gout, Acute "I take 2 pills at the start of a big gout attack and the last pill of the day one hour later. It took 13 hours for relief of severe pain to reduce by 50%. But for 13 hours, I couldn’t walk even with a cane. At 19 hours, I could walk with no cane. 24 hours after the start, slight diarrhea, but I could walk with no limp."

8 / 10
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5 Report
  • CHa...
  • Taken for 1 to 6 months
  • September 19, 2015

Colchicine for Gout, Acute "After 60 days, I saw ZERO improvement. My big right toe is as enlarged as ever. I am grateful, from what I read, that I never had any pain. For this price for a generic, no less, I have to seriously consider having my doctor move me on to another treatment."

1 / 10
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16 Report
  • Pai...
  • Taken for 1 to 6 months
  • November 22, 2019

Colchicine "This medication saved me from a lot of pain from Behcet disease (blood vessel inflammation throughout your body). I used to hurt so bad daily, and now it's just off and on, and I can have good days! I had no side effects from this medication."

10 / 10
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8 Report
  • trv...
  • June 7, 2009

For Gout, Acute "This is a useful drug, but care must be taken not to take too much when trying to get relief. The maximum start-up dose is usually greater than that needed to create problems in sensitive individuals, or if taken with another (incompatible) drug. I took 6 x 0.5 mg tablets for 2 days recently for an attack of left toe gout while starting on Simvastatin (for blood lipid lowering) and ended up with severe diarrhea (without any stomach pain). This knocked back the gout attack also, but cessation of therapy allowed it back with a vengeance, and two very bad nights followed. I have cleared the statin after 2 days, so will start a low dose of colchicine again if needed tonight, but keeping to 1-2 mg max dose in the future."

7 / 10
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20 Report
  • Dob...
  • October 12, 2019

For Gout, Acute "Wish the doctor would have warned about the diarrhea. Taking this and indomethacin at the same time. I’ve had flare-ups for 20 years, about once a year. First time taking this. Instructions were to take two 0.6 mg tablets, then one hour later take another. Then, twelve hours later, another. Was thinking about getting a haircut today, but that might be out, lol."

7 / 10
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9 Report
  • iPe...
  • Taken for 5 to 10 years
  • February 15, 2025

Colchicine "I was diagnosed with Behçet’s in 2019, after years of becoming sicker and sicker; finally, lesions on/around my eyes got a diagnosis. I was put on Otezla & Colcrys immediately. Colcrys 0.6 mg 2 x a day. After taking both, I noticed I was feeling a different kind of unwell. Hard to explain, but after experimenting, I realized it was the 2nd Colcrys making me feel badly. I can’t explain the feeling - it just made my body feel wrong. So, I’ve been on 1 a day since 2019. A month ago, I was waking up in my sleep with gnarled hands. The pain was excruciating; my fingers were huge like sausage, and I could not straighten them. I was in the middle of moving and suffered through the horrible pain and numbness too. I was living on Tylenol; I finally did some research and found there are rare cases of Colcrys basically “poisoning” your body. I stopped 2 days ago and am SO much better. Just a heads up to anyone seeking answers - it works great - until it doesn’t."

5 / 10
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1 Report
  • Vam...
  • May 25, 2013

Colchicine for Gout, Acute "After two days of severe pain and a visit to the doctor, blood work and an x-ray came up with a problem. Never had any type of gout/arthritis related problem before. Crystals were found on my wrist. After two days of taking Colcrys, wrist is still stiff and hurting, but pain is bearable."

7 / 10
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15 Report
  • Dul...
  • July 13, 2017

For Gout, Acute "Extremely prolonged first attack of gout. Repeat visits to GP, prescribed various drugs, then colchicine. Only 4-day course. Worked within a day. Pure relief! Side effects: really sudden diarrhea which lasted 24 hours. Benefits definitely outweigh side effects."

8 / 10
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11 Report
  • Col...
  • Taken for 1 to 2 years
  • June 22, 2019

For Gout, Acute "This medicine works perfectly. I took one 0.6 mg at the first sign of an attack and another 0.6 mg 4 hours later. Then the 3rd one 12 hours later. Back to normal the next day. Make sure you take it with a meal at the very first sign of a gout flare-up. Also, stay away from tofu and tomatoes if you don’t want to feel the pain, and colchicine has side effects and is very dangerous if you overdose. I mean stomach upset and muscle weakness within 7 days from the last pill."

10 / 10
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10 Report
  • G R...
  • Taken for 1 to 2 years
  • February 16, 2018

For Gout, Acute "I first was prescribed colchicine about two years ago after a flare occurred following an 18-hour drive. I woke during the night in severe pain and with swelling and redness. I improved significantly about 24 hours later. So I believe it is safe to say that I responded well to the drug with no serious side effects."

8 / 10
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9 Report
  • dc ...
  • Taken for less than 1 month
  • January 3, 2018

For Gout, Acute "I tolerated great pain for days to avoid taking drugs. But, at some point, I take this because the pain becomes unbearable. When ibuprofen alone is not getting the job done, this stuff is awesome, and usually only a few doses over a few days are needed."

9 / 10
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10 Report
  • Vik...
  • Taken for 6 months to 1 year
  • September 22, 2016

For Gout, Acute "Have suffered gout attacks for 40 years. Taking the prescribed dosage resulted in diarrhea after three days. Now I take a single 500 mcg tablet for one or two days at the first sign of an attack. This proves effective with no side effects. It also means I need to keep a supply of colchicine at hand."

10 / 10
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16 Report
  • ros...
  • Taken for 1 to 2 years
  • June 13, 2024

For Pseudogout, Prophylaxis "Misdiagnosed with RA for years. Nothing worked. Drugs were more intense. Then tried this. Life restored in two weeks. Can cause severe diarrhea, so I have to cut down or discontinue for a few weeks. Worth it!"

8 / 10
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2 Report
  • Jim...
  • Taken for 10 years or more
  • November 26, 2018

For Familial Mediterranean Fever "I was diagnosed almost 50 years ago with FMF. Colcrys brand does not work the same as my other brand of colchicine, which I cannot get in the U.S. Colchicine is my choice for feeling better with my diagnosis."

9 / 10
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8 Report
  • dj...
  • Taken for 2 to 5 years
  • June 25, 2012

For Gout, Acute "I have had gout attacks in both knees, elbows, wrists, big toes, and thumbs. One of my doctors put me on 0.6 mg of colchicine daily, and that worked to control the gout. Now the doctor that took over for her said I can't be on it daily, and now I have had gout in my right thumb and then my left thumb in 3 weeks since I quit the daily dose."

7 / 10
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13 Report
  • The...
  • Taken for less than 1 month
  • January 14, 2016

For Gout, Acute "I have been having gout attacks for about 3 years now. My doctor prescribed allopurinol daily to help keep my uric acid levels down. I was prescribed Colcrys as an anti-inflammatory, and I have to say it does absolutely nothing for the pain. My wife, who has never had a gout flare in her entire life, believes Colcrys is a miracle drug. So I take it just to humble her. I wouldn't suggest this medication to anyone. I wish I could give it negative stars as a review."

1 / 10
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13 Report
  • il ...
  • November 4, 2009

For Gout, Acute "I am subject to relatively frequent gout flare-ups, every 2-3 months or so. At the first symptoms, I take one 0.5 mg of colchicine every three hours, and most of the time after 2-3 pills the pain is gone. I also take 1-2 pills of Imodium to avoid the diarrhea. It works fine for me."

8 / 10
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15 Report
  • NKa...
  • April 4, 2019

For Sarcoidosis "I'm 39 years old and was in a car accident when I was 16, resulting in 16 surgeries. I didn't have anything specific happen to my heart, but I had a lot of damage to that area (broken ribs, bleeding liver and kidneys, and collapsed lungs). Within a few months, I started having severe pain in my heart and after several trips to the ER, I was diagnosed with pericarditis. It's inflammation of the sac that holds the heart and feels like a heart attack 24/7. My treatment over the years has been 800 mg ibuprofen every 4 hours and colchicine. Within 12 hours, my flare-up begins to get a little better and by day three of taking the medication, I'm almost back to normal. I haven't had any upset stomach issues or weird side effects. My toes are a little tingly, but I can handle that... can't handle the feeling of having knives going into my neck and chest with an elephant sitting on my chest. I only take this medication when I have a flare-up every 6-12 months."

10 / 10
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9 Report
  • dbt...
  • Taken for 6 months to 1 year
  • November 19, 2015

For Gout, Acute "Colchicine really helped my gout flares when I took the 2 pills followed by 1 more pill, but I also had some side effects. My stomach hurt, and I felt dizzy. I am type II diabetic, and my blood sugar levels were higher on the day I took colchicine. My doctor prescribed a daily dose of colchicine, and I only took that for a short time. I really had a terrible reaction to the daily dose. I will continue to take it for sporadic gout attacks."

10 / 10
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10 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.