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Chlorpheniramine / hydrocodone and Headaches: What Users Say

Brand names: Tussionex Pennkinetic, Hydrocodone GF, TussiCaps, HyTan

Headaches: mentioned by 8 users (6.1%)

Based on user experiences from 132 Chlorpheniramine / hydrocodone reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

drowsiness 11.4%
headaches 6.1%
tiredness 5.3%
cough 3.8%
itching 3.8%
brain fog 3.0%
anxiety 2.3%
lightheadedness 2.3%
pain 2.3%
sleepy 2.3%

Reviews for Chlorpheniramine / hydrocodone

Commonly mentioned side effects
  • TBa...
  • Taken for less than 1 month
  • February 28, 2016

Chlorpheniramine / hydrocodone for Cough "This is hands down the best cough medicine I've ever taken. I had a cough so severe that I wet myself or threw up during uncontrollable coughing fits. Needless to say, I couldn't sleep at night for more than the few hours when I just passed out from total exhaustion. My first dose of Tussionex didn't totally get rid of the cough, but it did cut it by about 50%. The second dose helped more. My third dose was last night, and it made it possible for me to get a good night's sleep for the first time in two weeks. I did wake up once with a bad headache, but I can't tell if it's a side effect of the medicine or just part of being sick. Anyway, I'll trade a headache for vomiting from coughing fits any day."

8 / 10
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33 Report
  • Wat...
  • Taken for less than 1 month
  • November 17, 2015

Chlorpheniramine / hydrocodone for Cough "This is my go-to cough medicine, it absolutely works the best for bronchitis cough or sinus infection. I have experienced headaches with this but found that if I drink a lot of water when I take it, that helps. We call it super syrup in our house."

10 / 10
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22 Report
  • jla...
  • August 26, 2013

Chlorpheniramine / hydrocodone for Cough "This medication will take a cough away, but I didn't like the side effects. I normally react great to pain meds, but not on this. Couldn't sleep the first night. Woke up with a severe headache. Had to take another dose for this cough and still bad headache. Can see this will turn to a migraine. Was so hopeful of this medication."

6 / 10
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24 Report
  • jla...
  • August 26, 2013

Chlorpheniramine / hydrocodone for Cough "This medication will take a cough away, but I didn't like the side effects. I normally react great to pain meds, but not on this. Couldn't sleep the first night. Woke up with a severe headache. Had to take another dose for this cough and still bad headache. Can see this will turn to a migraine. Was so hopeful of this medication."

6 / 10
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24 Report
  • Anonymous
  • February 23, 2009

Chlorpheniramine / hydrocodone for Cough "This stuff is amazing when you are really sick. A severe cough was making my head and neck hurt so bad. After about 20 minutes of taking Tussionex, my cough was much improved, and my neck/headache almost non-existent. I was prescribed this after codeine wasn't helping at all. Will definitely take it again if needed."

10 / 10
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10 Report

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  • Sev...
  • Taken for less than 1 month
  • January 27, 2013

For Cough "Had a cough so bad it was hurting my back and gave me terrible headaches. Was first prescribed another product, which did little. Have been taking this new prescription for a couple of days now (only need 1 tsp every 12 hrs)...amazing. Finally feeling like I'm getting better. Cough is much less, not nearly as tired as I was (was sleeping 16-20 hr days), been awake most of today. Thank you so much!"

10 / 10
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9 Report
  • Anonymous
  • October 2, 2009

Chlorpheniramine / hydrocodone for Cold Symptoms "Was given this medicine for upper respiratory tract infection. It helps the cough but makes you feel really out of it. With this prescription, I have had headaches. I'm on the 12-hour/1 tsp dosage. I would recommend this drug before you go to bed."

5 / 10
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4 Report
  • mam...
  • Taken for less than 1 month
  • December 29, 2012

Chlorpheniramine / hydrocodone for Cough "Helps with cough, however, experiencing severe headache with use of this medication. Almost bad enough to go to the emergency room."

5 / 10
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11 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.