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Wellbutrin User Reviews & Ratings (Page 5)

Wellbutrin has an average rating of 6.8 out of 10 from a total of 765 reviews on Drugs.com. 59% of reviewers reported a positive experience, while 22% reported a negative experience.

Reviews for Wellbutrin

Commonly mentioned side effects
  • Kri...
  • Taken for 6 months to 1 year
  • February 28, 2025

For Major Depressive Disorder "This is the most amazing medication I've ever taken. I've had issues with alcohol, and I'm on day 3 after increasing my dose, and I had zero cravings for alcohol today, which is crazy. I am also way more motivated and getting so much done at work. Before, I felt like I just wanted to sleep all day long. I was so negative every day, cried all the time, genuinely hated the idea of having to live another day. I can't even believe the change in myself in just a matter of days. I feel happy again and have a lot of energy. For anyone wanting to try this, I absolutely recommend it, it's life-changing!!"

10 / 10
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  • Lif...
  • Taken for less than 1 month
  • February 27, 2025

For Depression "Before I started taking Wellbutrin, I was very tired, stressed, had difficulty concentrating, sad, and unmotivated. Within a week of being on 150 mg a day, I felt such a tremendous positive change. I sleep better too. Now I am actually looking forward to the rest of my life instead of dreading it. I feel inspired, more disciplined, and my mood is stable. I hope this medication continues to support me as a method in my toolbox to improve the quality of my life."

10 / 10
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  • Mik...
  • January 22, 2020

For Major Depressive Disorder "Stopped taking Suboxone for opiate addiction and Wellbutrin saved my life. Only thing I use that I should’ve looked into years ago for my depression, anxiety, and slight ADHD! Highly recommend it to opiate users coming off blockers or meds. Side effects: insomnia for the first week, and dry mouth. Otherwise, I’m a big placebo guy but I noticed an instant change in mood (for the better)!"

10 / 10
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Frequently asked questions

  • Anonymous
  • Taken for 6 months to 1 year
  • July 1, 2017

For Depression "This drug has saved my life! I have struggled with methamphetamine addiction for about 4 years now. The hardest part about quitting was the extreme depression and suicidal thoughts. They always caused me to relapse. My physician prescribed Wellbutrin and it has worked like a miracle. I have been clean for over half a year and feel like I have my old life back! My relationships are healing and my family feels like they have their son/brother back. I am back in college and passing my classes! I don't attribute all that to the drug. Counseling and AA were extremely helpful but I know it was Wellbutrin that got me through the horrible depression to the other side. Only upfront side effects I had were jitteriness and dry mouth."

9 / 10
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  • hso...
  • April 24, 2016

For Depression "Probably saved my life. This is the first antidepressant I tried as I was scared of some of the nasty side effects of the SSRIs (sexual, weight gain, tiredness). I was on Wellbutrin XL 150 mg for 1-2 months and then have been on 300 mg XL for 3 months now. Getting on it was a little strange, as I had some side effects of anxiety at first, but actually have not had a panic attack since starting. Just know that it doesn't really help with anxiety/OCD symptoms (but I've been going to therapy for that). Really made me motivated to get work done (never been the case for me) without that craziness feeling from Adderall. Very consistently good mood and makes me want to be alive. Also increased sex drive + motivation for exercise is a plus."

8 / 10
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  • smw...
  • Taken for 5 to 10 years
  • July 20, 2012

For Depression "I'm 33 years old. I've been on this medication for 6 years. My mood, temper, and life in general are so much better. I went several years with depression that came on with postpartum. In a state of denial about my condition and not wanting to be labeled, I would not seek treatment. I wish I would have done so much sooner. I cannot say enough about Wellbutrin, it has changed my life. I deal with stress, death, and everyday life of raising two teenagers now, which I firmly believe I could not have done without it. I have found you can be happy and would encourage people to get the mental help they need because medications like this one are life-changing. I can also add side effects have not been an issue for me at all."

10 / 10
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  • Ale...
  • Taken for less than 1 month
  • December 30, 2023

"I have GAD and ADHD, as well as going through postpartum depression which is presenting mainly as rage. I haven't taken any sort of medication for 10 years to treat the anxiety, and I've only now just accepted the fact that I needed to try some medication for my ADHD. I'm nervous about stimulants so my doctor prescribed 150mg Wellbutrin XL. I must say - I am pleasantly surprised. No medication (I have tried about 5 different antidepressants in my life) has made this much of a difference for me. I've only been taking it for 3 days and I'm already noticing a huge shift in my mood, and I randomly got up and scrubbed down all the surfaces in my kitchen (which haven't been done for god knows how long). I feel the urge to be productive and I'm less irritable with my kids. I'm hoping this continues and so far I have no negative side effects whatsoever, which shocks me. Give it a try!"

10 / 10
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More FAQ

  • Sar...
  • Taken for less than 1 month
  • October 20, 2024

"Female, 27, 150 mg XL for overeating disorder, ADHD, depression, and anxiety. After 10 days, insomnia improved by switching to taking it at night right as I'm falling asleep. It increased focus, energy, and contentment while reducing hunger. Initial agitation subsided quickly. Previous meds like Adderall, Vyvanse, and SSRIs had unwanted side effects, but Wellbutrin combines the best of both, allowing creativity and emotional connection. It's improved disordered eating, social interactions, and focus on work and creativity. Lost 3 lbs, feel more accountable, and have a better schedule. Glad I gave it a chance after being hesitant due to online reviews. It's nice to have my life back and feel like myself. I will update if anything changes, but for now I'm so grateful for this medicine."

10 / 10
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  • Los...
  • May 3, 2009

For Depression "It has helped me a lot with my depression and anger problems. For the first time in 9 years, I don't wake up mad at the world with homicidal thoughts. The side effects that I experienced are dizziness when I stand up too fast and my loss of appetite (not a bad thing). I was overweight anyway. I've only been on it for 2 weeks and have lost 13 pounds, but it makes me feel so much better about myself."

10 / 10
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  • McL...
  • Taken for 1 to 6 months
  • May 20, 2014

For Depression "I tried a couple of different SSRIs and found that most of them gave me bad side effects and made me feel empty, so when I heard about Wellbutrin, I asked my doctor if I could try it. It's one of the few that also doesn't give you a decreased sex drive. I was a bit scared after hearing some of the negative reviews, but this medication works wonders for me. I have had no side effects at all, and within a day, I started feeling better. I would recommend this to anyone who hasn't had luck with SSRIs."

10 / 10
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  • JIC...
  • Taken for 1 to 6 months
  • November 19, 2016

For Depression "I tried for 2 years after a major life change to get my life back. All the SNRIs and SSRIs gave me the worst side effects, and I became more depressed, dizzy, had migraines, and felt suicidal. This wasn't me, and every doctor wrote me off as being a bad patient. I was ready to throw in the towel and tried a low dose of Wellbutrin, and OMG. 2 months later, I was completely myself, and 6 months later, I'm medication-free. Don't give up, keep trying. I thought my life was over, and I was a difficult patient. Don't let message boards or doctors rule your life. If something isn't working, don't stay on it!"

9 / 10
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  • mom...
  • Taken for less than 1 month
  • November 15, 2012

For Depression "This is the most amazing medication for depression! I have used it in the past, and I am so glad to start back on it again. I have had so many bad things happen, that it is time for some good. I am grateful for the way it helps me see the bright side of life, instead of living so unhappily and feeling hopeless. If you have ever thought of suicide, please don't do it. I know this medicine helped me from doing it in my past, it's wonderful. Problems are temporary."

10 / 10
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  • Ddd...
  • Taken for 1 to 6 months
  • February 29, 2020

"Aside from the minor headaches and nausea, my experience has been better than most of the recent reviews. I started on Lexapro several years ago, but the sexual side effects were just too much for me compared to the minor effect it had on my well-being. I've had none of that with Wellbutrin, and I feel much better. I've lost approximately 35 lbs since starting, though I've also changed my diet and exercise patterns. My brain is no longer a swirl of indistinguishable thoughts, and I'm able to focus for more than a second at a time."

8 / 10
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  • Wei...
  • September 11, 2014

For Major Depressive Disorder "I feel great and it has been only 3 days. I have battled with Major Depressive Disorder and Post-Traumatic Stress Disorder, starting treatment in 2006. When I came back to the States, I was in 4 hospitals for months, treated by the best on 7-10 different medications at different times. I had ECT, etc. For me, all the medications did not do a thing for me but get suicidal thoughts and gained 60 pounds. One antidepressant medicine I was on for a few years was Lexapro. I was in Aruba and wanted to die. Through much thought and discussion, I weaned off of all the antidepressants. After 8 years, just last week a doctor said I never have been on Wellbutrin and put me on it. I have, for the last few months, been really down and out. Immediately, I feel better. It took only 8 years and wasted time in the hospital & ECT."

9 / 10
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  • ber...
  • Taken for 1 to 6 months
  • January 11, 2020

For Depression "I started Wellbutrin 4 months ago at age 40. It was my first time using medication, although I've battled depression (and a subsequent eating disorder) since I was a child. A few years ago, anxiety started tormenting me. I couldn't live like this anymore. My GP started me on 150 mg, but after 6 weeks with no difference, upped it to 450. Finally, I realized the change: I was calmer, no longer judgmental towards myself, my unsatisfactory life situation, and my body. The anxiety and depression were gone. I treated myself with self-compassion and acceptance - all firsts for me! However, I also didn't care about exercising, and I've been an athlete and hiker all my life, so my energy level had evidently decreased. These past 4 months have been a lovely, gentle reprieve from the perfectionism and pressure I've put on myself my whole life. I've learned CBT and DBT therapies and am in recovery from my eating disorder. But now I want to feel energetic again and to wean myself off of Wellbutrin. I'm very grateful for it though!"

8 / 10
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  • pea...
  • July 31, 2008

For Depression "I've been taking this medication for a couple of years. I no longer obsess over things and am no longer as depressed as I used to be. They seem to keep me in balance with my emotions. I would recommend this to anyone with depression and also compulsive behavior."

9 / 10
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  • Bec...
  • January 13, 2015

For Major Depressive Disorder "Wellbutrin has saved my life. It's a miracle. About 6 months ago, I was diagnosed with major depressive disorder and localized anxiety disorder. I was put on Lexapro, which didn't help much, and the side effects were awful: total loss of sex drive, bad headaches, and nightmares every night. Then, about 3 months ago, they put me on 200mg of Wellbutrin daily, and I started feeling better within a week. It was incredible! I am now happier than I have ever been. I feel like a new, improved version of myself. My sex drive has drastically improved, but my appetite has not returned. In fact, I have lost weight despite not changing my eating or exercising habits. Other than those, I have no side effects."

10 / 10
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  • sun...
  • Taken for 1 to 2 years
  • January 19, 2020

For Major Depressive Disorder "I have suffered from MDD for the majority of my life. I struggled for 5 years and through 16 different meds till we landed on Wellbutrin. One of the selling points for me is that this particular antidepressant is well known for not causing weight gain. And I can attest to that! On top of it not causing ANY side effects whatsoever, I started to feel better emotionally/physically within 2 weeks of being on Wellbutrin (Bupropion). I take two 150mg a day in the morning with my breakfast. I will say it did NOT help my anxiety even one single ounce, however with how much it has done for my depression, I will happily take a second medication for my anxiety. I have more energy, it gives me a huge boost in my mood, and that hasn’t changed! I haven’t had to switch or change meds and I have been on it for just over a year now. Thank goodness for this medication, seriously, a drastic difference, I finally get to be finally me!"

10 / 10
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  • gra...
  • Taken for 1 to 6 months
  • June 16, 2015

For Depression "I've been on Prozac for about 20 years, and it's been a lot of help, but at age 68, I found myself wanting to nap a lot more and my motivation decreasing. I switched to Wellbutrin, and once the therapeutic dose was established, I began to feel better within a week or two. I feel more energetic and yet more composed and at ease. I'm very pleased with this drug, not the least because my sex life has returned. I think my life would have been different if I'd started it 20 years ago."

10 / 10
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  • eli...
  • June 3, 2016

For Depression "Shortly after my 20th birthday, I developed what I later found out was major depression. After starting counseling, I reluctantly started taking Wellbutrin, and within a few days, I was a noticeably different person than I had been the past 6 months. I began to act like my old self again, gaining confidence, and for the most part, being free from all of my depression episodes that had occurred daily. The biggest side effects that I experienced were weight loss/loss of appetite and trouble falling asleep at night, but after about two weeks, those both went away. I've now been taking 300mg daily for about six weeks and feel great! I'd encourage you to give this medication a try because it can potentially really change your life."

9 / 10
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  • Con...
  • January 5, 2014

For Depression "I've been taking bupropion 75mg twice a day for the past 6 weeks and I feel like I'm finally back to the real me. I'm 18 and have been dealing with depression, but this medication helped me tremendously. I was originally on Paxil, but due to sexual side effects, I switched to this and it restored my sex drive. I also have a little bit of anxiety, but this medication cleared that up as well. The first week was hard. I experienced heart palpitations, very anxious, ridiculous energy, and I was easily agitated. After the first week, those side effects slowly diminished and now I don't have them at all. That is the only reason I didn't give this medicine a 10. It saved my life. I HIGHLY recommend this to any who doesn't want sexual side effects."

9 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • January 4, 2017

For Depression "Started Wellbutrin XL at 150 mg once a day to treat depression and anxiety, although was more concerned about depression. The first week I was on it, I was absolutely miserable. I did not sleep or eat at all, and was crying constantly, and I think it definitely worsened my depression. However, I called my doctor and had my dose lowered to 75 mg and not extended release, and I immediately felt better. I have been on that dosage for about 6 months now, and I feel amazing. I am able to control my emotions so much better, and I rarely have meltdowns (I used to have a complete meltdown anytime anything negative happened to me). I definitely plan on staying on Wellbutrin. Would just recommend you make sure you are on the right dose."

8 / 10
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  • Kuf...
  • Taken for less than 1 month
  • November 9, 2015

For Depression "I'm a 24-year-old male. I started taking Wellbutrin a week ago. I did 150mg for 3 days, then 2x a day now. I noticed a change by the 3rd day. My coworkers said I was more energetic and a nicer person. I'm on day 7 now and I am thinking more clearly than I have in a long time. I don't get frustrated so easily, I can fall asleep a lot faster because I'm not worrying all the time, and I get up in the morning with ease. I really like this antidepressant. It's the first one that has actually worked for me."

9 / 10
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  • Pia...
  • Taken for 1 to 6 months
  • May 12, 2013

For Depression "I am a 53-year-old prostate cancer survivor (radical prostatectomy and adjuvant radiation treatment) with depression/anxiety. I started on 150mg of Wellbutrin 6 months ago. Recently, I started having major depression/anxiety feelings about work. I am now taking 150mg twice a day, and I feel great. I cannot believe the difference in my mood from dismal depression to optimism. I also quit smoking and drinking. I've been doing the South Beach diet with moderate exercise (30-40 minutes walking on a treadmill) and have lost 20 pounds, but I was about 100 pounds overweight so I have a long way to go. I am just a few days into the 150mg twice a day regimen, but the results with respect to mood change have been remarkable."

9 / 10
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  • Anonymous
  • June 30, 2010

For Depression "I was tired all the time. I have been to Iraq and back, and the way I felt was just the way I thought I should feel. I was lazy sometimes, would put things off, irritated, and got upset quickly. For years and years, I just thought that was me. I was a major drinker and smoker, couldn't ever get enough sleep, and had no motivation to get out of bed. Again, I thought that was me. I started to have anxiety after my wife had a miscarriage. Then we got pregnant again, and things really started to get out of control. Wellbutrin saved me. I quit drinking and smoking! I'm motivated, love being a dad, work is great! Slight sexual side effects."

8 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.